MA37955A1 - Beta-secretase inhibitors - Google Patents
Beta-secretase inhibitorsInfo
- Publication number
- MA37955A1 MA37955A1 MA37955A MA37955A MA37955A1 MA 37955 A1 MA37955 A1 MA 37955A1 MA 37955 A MA37955 A MA 37955A MA 37955 A MA37955 A MA 37955A MA 37955 A1 MA37955 A1 MA 37955A1
- Authority
- MA
- Morocco
- Prior art keywords
- beta
- secretase inhibitors
- inhibitors
- disorders
- bace1
- Prior art date
Links
Abstract
La présente invention concerne des acylguanidines spirocycliques et leur utilisation en tant qu'inhibiteurs de l'activité enzymatique bêta-secrétase (bace1), des compositions pharmaceutiques contenant celles-ci, et des procédés d'utilisation de celles-ci comme agents thérapeutiques dans le traitement de troubles neurodégénératifs, de troubles caractérisés par un déclin cognitif, un déficit cognitif, la démence et des maladies caractérisées par la production d'agrégats de ß-amyloïdes.The present invention relates to spirocyclic acylguanidines and their use as inhibitors of enzymatic beta-secretase activity (bace1), pharmaceutical compositions containing them, and methods of using them as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by the production of β-amyloid aggregates.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261693512P | 2012-08-27 | 2012-08-27 | |
PCT/US2013/056566 WO2014035860A1 (en) | 2012-08-27 | 2013-08-26 | Inhibitors of beta-secretase |
Publications (1)
Publication Number | Publication Date |
---|---|
MA37955A1 true MA37955A1 (en) | 2017-10-31 |
Family
ID=60765487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37955A MA37955A1 (en) | 2012-08-27 | 2013-08-26 | Beta-secretase inhibitors |
Country Status (1)
Country | Link |
---|---|
MA (1) | MA37955A1 (en) |
-
2013
- 2013-08-26 MA MA37955A patent/MA37955A1/en unknown
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