MA38473B1 - (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of - Google Patents
(2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors ofInfo
- Publication number
- MA38473B1 MA38473B1 MA38473A MA38473A MA38473B1 MA 38473 B1 MA38473 B1 MA 38473B1 MA 38473 A MA38473 A MA 38473A MA 38473 A MA38473 A MA 38473A MA 38473 B1 MA38473 B1 MA 38473B1
- Authority
- MA
- Morocco
- Prior art keywords
- aza
- bicyclo
- heptane
- cyano
- inhibitors
- Prior art date
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La présente invention concerne des (benzyl-cyano-méthyl)-amides de l'acide 2-aza-bicyclo[2.2.1]heptane-3-carboxylique de formule (1) et leur utilisation comme inhibiteurs de la cathépsine c, des compositions pharmaceutiques contenant ceux-ci, et des méthodes d'utilisation de ceux-ci comme agents pour le traitement et/ou la prévention de maladies associées à l'activité de la dipeptidyl peptidase i, par exemple des maladies respiratoires.The present invention relates to (benzyl-cyano-methyl) -amides of 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid of formula (1) and their use as cathepsin-c inhibitors, compositions pharmaceutical compositions containing these, and methods of use thereof as agents for the treatment and / or prevention of diseases associated with the activity of dipeptidyl peptidase i, for example respiratory diseases.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13159240 | 2013-03-14 | ||
PCT/EP2014/054794 WO2014140075A1 (en) | 2013-03-14 | 2014-03-12 | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c |
Publications (2)
Publication Number | Publication Date |
---|---|
MA38473A1 MA38473A1 (en) | 2016-04-29 |
MA38473B1 true MA38473B1 (en) | 2016-11-30 |
Family
ID=47845866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA38473A MA38473B1 (en) | 2013-03-14 | 2015-10-09 | (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR095376A1 (en) |
MA (1) | MA38473B1 (en) |
-
2014
- 2014-03-12 AR ARP140100916A patent/AR095376A1/en unknown
-
2015
- 2015-10-09 MA MA38473A patent/MA38473B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AR095376A1 (en) | 2015-10-14 |
MA38473A1 (en) | 2016-04-29 |
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