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Application filed by Boehringer Ingelheim IntfiledCriticalBoehringer Ingelheim Int
Priority to MA39260ApriorityCriticalpatent/MA39260A1/en
Publication of MA39260A1publicationCriticalpatent/MA39260A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La présente invention concerne des (benzyl-cyano-méthyl)-amides de l'acide 2-aza-bicyclo[2.2.1]heptane-3-carboxylique de formule (1) et leur utilisation comme inhibiteurs de la cathépsine c, des compositions pharmaceutiques contenant ceux-ci, et des méthodes d'utilisation de ceux-ci comme agents pour le traitement et/ou la prévention de maladies associées à l'activité de la dipeptidyl peptidase i, par exemple des maladies respiratoires.The present invention relates to (benzyl-cyano-methyl) -amides of 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid of formula (1) and their use as cathepsin-c inhibitors, compositions pharmaceutical compositions containing these, and methods of use thereof as agents for the treatment and / or prevention of diseases associated with the activity of dipeptidyl peptidase i, for example respiratory diseases.
MA39260A2014-03-122014-03-12
(2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of
MA39260A1
(en)