MA31985B1 - (r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin - Google Patents

(r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin

Info

Publication number
MA31985B1
MA31985B1 MA32927A MA32927A MA31985B1 MA 31985 B1 MA31985 B1 MA 31985B1 MA 32927 A MA32927 A MA 32927A MA 32927 A MA32927 A MA 32927A MA 31985 B1 MA31985 B1 MA 31985B1
Authority
MA
Morocco
Prior art keywords
pyrazin
propionamide
tetrahydropyran
crystalline
phenyl
Prior art date
Application number
MA32927A
Other languages
Arabic (ar)
English (en)
Inventor
Jeanette Tower Dunlap
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40451065&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA31985(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA31985B1 publication Critical patent/MA31985B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

2-(4-cyclopropanesulphonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)-propionamide cristallin.
MA32927A 2008-01-15 2010-06-16 (r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin MA31985B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2113308P 2008-01-15 2008-01-15
PCT/US2009/030241 WO2009091634A1 (fr) 2008-01-15 2009-01-07 2-(4-cyclopropanesulphonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)-propionamide cristallin

Publications (1)

Publication Number Publication Date
MA31985B1 true MA31985B1 (fr) 2011-01-03

Family

ID=40451065

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32927A MA31985B1 (fr) 2008-01-15 2010-06-16 (r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin

Country Status (22)

Country Link
US (1) US20090181981A1 (fr)
EP (1) EP2265271A1 (fr)
JP (1) JP2011509934A (fr)
KR (1) KR20100092061A (fr)
CN (1) CN101909629A (fr)
AR (1) AR070107A1 (fr)
AU (1) AU2009205606A1 (fr)
BR (1) BRPI0907165A2 (fr)
CA (1) CA2712245A1 (fr)
CL (1) CL2009000004A1 (fr)
CO (1) CO6280489A2 (fr)
DO (1) DOP2010000216A (fr)
EA (1) EA201070853A1 (fr)
EC (1) ECSP10010347A (fr)
IL (1) IL206102A0 (fr)
MA (1) MA31985B1 (fr)
MX (1) MX2010007784A (fr)
PE (1) PE20091313A1 (fr)
TN (1) TN2010000299A1 (fr)
TW (1) TW200934772A (fr)
WO (1) WO2009091634A1 (fr)
ZA (1) ZA201003909B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI432422B (zh) 2007-08-22 2014-04-01 Astrazeneca Ab 環丙基醯胺衍生物
TW201039825A (en) 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
CA2789884A1 (fr) * 2010-02-18 2011-08-25 Astrazeneca Ab Formes solides comprenant un derive de cyclopropylamide
SG183274A1 (en) 2010-02-18 2012-09-27 Astrazeneca Ab Processes for making cyclopropyl amide derivatives and intermediates associated therewith
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
KR101220371B1 (ko) 2010-09-17 2013-01-09 현대자동차주식회사 베인펌프
EP2674517B1 (fr) * 2011-02-08 2018-10-03 Japan Agency for Marine-Earth Science and Technology Procédé de production d'un monocristal de calcite
JP2013014534A (ja) * 2011-07-04 2013-01-24 Daicel Corp ベンゾイルギ酸化合物、及びその製造方法
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr) 2011-09-27 2015-10-21 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046768A (en) * 1976-06-17 1977-09-06 Velsicol Chemical Corporation 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones
US6320050B1 (en) * 1999-03-29 2001-11-20 Hoffmann-La Roche Inc. Heteroaromatic glucokinase activators
US6610846B1 (en) * 1999-03-29 2003-08-26 Hoffman-La Roche Inc. Heteroaromatic glucokinase activators
US6353111B1 (en) * 1999-12-15 2002-03-05 Hoffmann-La Roche Inc. Trans olefinic glucokinase activators
KR100502033B1 (ko) * 2000-05-03 2005-07-25 에프. 호프만-라 로슈 아게 알키닐 페닐 헤테로방향족 글루코키나제 활성제
US6489485B2 (en) * 2000-05-08 2002-12-03 Hoffmann-La Roche Inc. Para-amine substituted phenylamide glucokinase activators
EP1282611B1 (fr) * 2000-05-08 2004-10-20 F. Hoffmann-La Roche Ag Phenylacetamides substitues et leur utilisation en tant qu'activateurs de la glucokinase
WO2002008209A1 (fr) * 2000-07-20 2002-01-31 F. Hoffmann-La Roche Ag Composes de benzene acetamide substitues par alpha-acyle et des alpha-heteroatomes en tant qu'activateurs de glucokinase
US6369232B1 (en) * 2000-08-15 2002-04-09 Hoffmann-La Roche Inc. Tetrazolyl-phenyl acetamide glucokinase activators
US6433188B1 (en) * 2000-12-06 2002-08-13 Wendy Lea Corbett Fused heteroaromatic glucokinase activators
BR0115999A (pt) * 2000-12-06 2003-09-30 Hoffmann La Roche Composto, composição farmacêutica que compreende o mesmo, sua utilização, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto
US6482951B2 (en) * 2000-12-13 2002-11-19 Hoffmann-La Roche Inc. Isoindolin-1-one glucokinase activators
US6911545B2 (en) * 2001-12-19 2005-06-28 Hoffman-La Roche Inc. Crystals of glucokinase and methods of growing them
PL378117A1 (pl) * 2003-02-11 2006-03-06 Prosidion Limited Tricyklopodstawione związki amidowe
JP4621198B2 (ja) * 2003-02-11 2011-01-26 プロシディオン・リミテッド トリ（シクロ）置換アミドグルコキナーゼ活性化化合物
CA2563192A1 (fr) * 2004-04-21 2005-11-03 Prosidion Limited Composes amide tri(cyclo)-substitues
WO2006016194A1 (fr) * 2004-08-12 2006-02-16 Prosidion Limited Phénylacétamides substitués et leur utilisation en tant qu’activateurs de la glucokinase
GB0418058D0 (en) * 2004-08-12 2004-09-15 Prosidion Ltd Fluorination process
GB0418046D0 (en) * 2004-08-12 2004-09-15 Prosidion Ltd Eantioselective process
JP2009514836A (ja) * 2005-11-03 2009-04-09 プロシディオン・リミテッド トリシクロ置換型アミド
EP1948644A1 (fr) * 2005-11-03 2008-07-30 Prosidion Limited Amides a substitution tricyclo
US20080293741A1 (en) * 2005-11-03 2008-11-27 Matthew Colin Thor Fyfe Tricyclo Substituted Amides as Glucokinase Modulators

Also Published As

Publication number Publication date
US20090181981A1 (en) 2009-07-16
CN101909629A (zh) 2010-12-08
DOP2010000216A (es) 2010-10-15
TW200934772A (en) 2009-08-16
MX2010007784A (es) 2010-08-09
CO6280489A2 (es) 2011-05-20
JP2011509934A (ja) 2011-03-31
EP2265271A1 (fr) 2010-12-29
WO2009091634A1 (fr) 2009-07-23
IL206102A0 (en) 2010-11-30
CA2712245A1 (fr) 2009-07-23
EA201070853A1 (ru) 2010-12-30
AU2009205606A1 (en) 2009-07-23
TN2010000299A1 (en) 2011-11-11
ECSP10010347A (es) 2010-09-30
PE20091313A1 (es) 2009-09-03
CL2009000004A1 (es) 2010-02-19
ZA201003909B (en) 2011-11-30
KR20100092061A (ko) 2010-08-19
BRPI0907165A2 (pt) 2015-07-14
AR070107A1 (es) 2010-03-17

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