MA30563B1 - Sels de n-hydroxy-3-[4-[[[2-(2-méthyl-1h-indol-3-yl)éthyl]amino]méthyl]phényl]-2e-2-propénamide - Google Patents

Sels de n-hydroxy-3-[4-[[[2-(2-méthyl-1h-indol-3-yl)éthyl]amino]méthyl]phényl]-2e-2-propénamide

Info

Publication number
MA30563B1
MA30563B1 MA31469A MA31469A MA30563B1 MA 30563 B1 MA30563 B1 MA 30563B1 MA 31469 A MA31469 A MA 31469A MA 31469 A MA31469 A MA 31469A MA 30563 B1 MA30563 B1 MA 30563B1
Authority
MA
Morocco
Prior art keywords
methyl
propenamide
indol
hydroxy
phenyl
Prior art date
Application number
MA31469A
Other languages
English (en)
Inventor
Murat Acemoglu
Joginder S Bajwa
Piotr Karpinski
Dimitris Papoutsakis
Joel Slade
Frank Stowasser
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38564366&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA30563(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA30563B1 publication Critical patent/MA30563B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La présente invention concerne la préparation et la caractérisation de sels de N- hydroxy-3-[4-[[[2-(2-méthyl-1H-indol-3-yl)éthyl]amino]méthyl]phényl]-2E-2- propénamide.
MA31469A 2006-06-12 2008-12-12 Sels de n-hydroxy-3-[4-[[[2-(2-méthyl-1h-indol-3-yl)éthyl]amino]méthyl]phényl]-2e-2-propénamide MA30563B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80452306P 2006-06-12 2006-06-12
US86999306P 2006-12-14 2006-12-14

Publications (1)

Publication Number Publication Date
MA30563B1 true MA30563B1 (fr) 2009-07-01

Family

ID=38564366

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31469A MA30563B1 (fr) 2006-06-12 2008-12-12 Sels de n-hydroxy-3-[4-[[[2-(2-méthyl-1h-indol-3-yl)éthyl]amino]méthyl]phényl]-2e-2-propénamide

Country Status (38)

Country Link
US (3) US20090197936A1 (fr)
EP (1) EP2032531B1 (fr)
JP (2) JP2009540005A (fr)
KR (2) KR20090026281A (fr)
AR (1) AR061298A1 (fr)
AU (1) AU2007257962B2 (fr)
BR (1) BRPI0712771A2 (fr)
CA (1) CA2654439C (fr)
CL (1) CL2007001692A1 (fr)
CR (1) CR10439A (fr)
DK (1) DK2032531T3 (fr)
EA (1) EA015212B1 (fr)
EC (1) ECSP088979A (fr)
ES (1) ES2570934T3 (fr)
GE (1) GEP20105125B (fr)
GT (1) GT200800279A (fr)
HK (1) HK1126496A1 (fr)
HN (1) HN2008001859A (fr)
HR (1) HRP20160291T1 (fr)
HU (1) HUE027126T2 (fr)
IL (1) IL195087A (fr)
JO (1) JO3138B1 (fr)
MA (1) MA30563B1 (fr)
ME (1) ME00531B (fr)
MX (1) MX2008015901A (fr)
MY (1) MY147345A (fr)
NO (1) NO341871B1 (fr)
NZ (1) NZ572547A (fr)
PE (1) PE20080937A1 (fr)
PL (1) PL2032531T3 (fr)
RS (1) RS54640B1 (fr)
SI (1) SI2032531T1 (fr)
SM (1) SMP200900002B (fr)
SV (1) SV2008003126A (fr)
TN (1) TNSN08501A1 (fr)
TW (1) TWI409254B (fr)
UY (1) UY30403A1 (fr)
WO (1) WO2007146715A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0712993A2 (pt) 2006-06-12 2012-04-17 Novartis Ag polimorfos de n-hidróxi-3-[4[[[2-(2-metil-1h-indol-3-il) etil]amino]metil]fenil]-2e-2-propenamida
MX2009007343A (es) * 2007-01-10 2009-07-15 Novartis Ag Formulaciones de inhibidores de desacetilasa.
US8003700B2 (en) * 2008-04-07 2011-08-23 Mutual Pharamaceutical Company, Inc. Colchicine solid complex; methods of making; and methods of use thereof
US8519002B2 (en) 2008-04-07 2013-08-27 Takeda Pharmaceuticals U.S.A., Inc. Colchicine solid complex; methods of making; and methods of use thereof
UY32297A (es) * 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
JP5263211B2 (ja) 2010-03-30 2013-08-14 ブラザー工業株式会社 サーバ、プリンタ、及び、サーバのためのコンピュータプログラム
EP2578570A1 (fr) 2011-10-07 2013-04-10 Almirall, S.A. Nouveau procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy)hexyl]amino}-1-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one via de nouveaux intermédiaires de synthèse
EP2641900A1 (fr) 2012-03-20 2013-09-25 Almirall, S.A. Nouvelles formes polymorphes de héminapadisylate de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy) hexyl]amino}-1-(R)-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one en tant qu'agoniste du récepteur adrénergique ß2
MA41544A (fr) 2015-02-19 2017-12-26 Novartis Ag Dosages de panobinostat pour le traitement du myélome multiple
WO2017221163A1 (fr) * 2016-06-21 2017-12-28 Alembic Pharmaceuticals Limited Nouveaux sels et formes polymorphes de panobinostat

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020354A1 (es) * 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
WO2005013958A1 (fr) * 2003-08-07 2005-02-17 Novartis Ag Inhibiteurs d'histone deacetylase utilises comme immunosuppresseurs
US20050228300A1 (en) * 2004-04-07 2005-10-13 Triage Data Networks Cuffless blood-pressure monitor and accompanying wireless mobile device
JP2009540007A (ja) * 2006-06-12 2009-11-19 ノバルティス アクチエンゲゼルシャフト N−ヒドロキシ−3−[4−[[[2−(2−メチル−1h−インドール−3−イル)エチル]アミノ]メチル]フェニル]−2e−2−プロペンアミドの塩の製造方法
BRPI0712993A2 (pt) * 2006-06-12 2012-04-17 Novartis Ag polimorfos de n-hidróxi-3-[4[[[2-(2-metil-1h-indol-3-il) etil]amino]metil]fenil]-2e-2-propenamida

Also Published As

Publication number Publication date
KR101629352B1 (ko) 2016-06-13
KR20090026281A (ko) 2009-03-12
TWI409254B (zh) 2013-09-21
AU2007257962A1 (en) 2007-12-21
WO2007146715A1 (fr) 2007-12-21
RS54640B1 (en) 2016-08-31
HK1126496A1 (zh) 2009-09-04
UY30403A1 (es) 2008-01-31
IL195087A (en) 2012-10-31
AU2007257962B2 (en) 2011-06-23
CA2654439A1 (fr) 2007-12-21
EA200802382A1 (ru) 2009-06-30
SI2032531T1 (sl) 2016-05-31
NO20090128L (no) 2009-03-11
IL195087A0 (en) 2009-08-03
JP2013256542A (ja) 2013-12-26
NO341871B1 (no) 2018-02-12
MX2008015901A (es) 2009-01-12
JO3138B1 (ar) 2017-09-20
HUE027126T2 (en) 2016-08-29
TNSN08501A1 (en) 2010-04-14
KR20150029765A (ko) 2015-03-18
EP2032531B1 (fr) 2016-02-10
BRPI0712771A2 (pt) 2012-09-25
US20090197936A1 (en) 2009-08-06
JP5771257B2 (ja) 2015-08-26
HN2008001859A (es) 2011-07-19
TW200815343A (en) 2008-04-01
EP2032531A1 (fr) 2009-03-11
EA015212B1 (ru) 2011-06-30
CR10439A (es) 2009-01-15
NZ572547A (en) 2011-06-30
DK2032531T3 (en) 2016-04-11
CL2007001692A1 (es) 2008-05-09
US20110112308A1 (en) 2011-05-12
JP2009540005A (ja) 2009-11-19
PE20080937A1 (es) 2008-08-29
ECSP088979A (es) 2009-01-30
PL2032531T3 (pl) 2016-07-29
ME00531B (fr) 2011-10-10
MY147345A (en) 2012-11-30
GT200800279A (es) 2010-06-16
GEP20105125B (en) 2010-11-25
AR061298A1 (es) 2008-08-20
CA2654439C (fr) 2014-08-05
HRP20160291T1 (hr) 2016-04-22
US20100286409A1 (en) 2010-11-11
ES2570934T3 (es) 2016-05-23
SMAP200900002A (it) 2009-01-14
SV2008003126A (es) 2011-07-05
SMP200900002B (it) 2010-01-19

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