MA28531B1 - Composition de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4 - Google Patents
Composition de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4Info
- Publication number
- MA28531B1 MA28531B1 MA29385A MA29385A MA28531B1 MA 28531 B1 MA28531 B1 MA 28531B1 MA 29385 A MA29385 A MA 29385A MA 29385 A MA29385 A MA 29385A MA 28531 B1 MA28531 B1 MA 28531B1
- Authority
- MA
- Morocco
- Prior art keywords
- pdea4
- pyrazolo
- pyridine
- inhibitor
- composition
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0405893A GB0405893D0 (en) | 2004-03-16 | 2004-03-16 | Compounds |
GB0505214A GB0505214D0 (en) | 2005-03-14 | 2005-03-14 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28531B1 true MA28531B1 (fr) | 2007-04-03 |
Family
ID=34962723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29385A MA28531B1 (fr) | 2004-03-16 | 2006-10-13 | Composition de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4 |
Country Status (15)
Country | Link |
---|---|
US (2) | US20080275078A1 (fr) |
EP (2) | EP1740590A1 (fr) |
JP (2) | JP2007529486A (fr) |
KR (1) | KR20060130744A (fr) |
AR (1) | AR048175A1 (fr) |
AU (1) | AU2005223351A1 (fr) |
BR (1) | BRPI0508843A (fr) |
CA (1) | CA2559629A1 (fr) |
IL (1) | IL178011A0 (fr) |
MA (1) | MA28531B1 (fr) |
NO (1) | NO20064450L (fr) |
PE (1) | PE20060078A1 (fr) |
RU (1) | RU2378274C2 (fr) |
TW (1) | TW200602051A (fr) |
WO (2) | WO2005090354A1 (fr) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0230045D0 (en) | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
CA2557004A1 (fr) * | 2003-12-19 | 2005-06-30 | Glaxo Group Limited | Composes pyrazolo [3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de la phosphodiesterase |
WO2005090354A1 (fr) | 2004-03-16 | 2005-09-29 | Glaxo Group Limited | Composes de pyrazolo[3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de pde4 |
EA200801997A1 (ru) | 2006-04-20 | 2009-04-28 | Глаксо Груп Лимитед | Новые соединения |
AR061571A1 (es) | 2006-06-23 | 2008-09-03 | Smithkline Beecham Corp | Compuesto sal del acido toluenosulfonico de 4-{[6-cloro-3-({[(2- cloro-3-fluorofenil) amino]carbonil} amino)- 2- hidroxifenil]sulfonil] -1- piperazinacarbxilato de 1.1-dimetiletilo, composicion farmaceutica que lo comprende su uso para la fabricacion de un medicamento combinacion farmaceutica con un |
NZ574533A (en) | 2006-08-01 | 2011-05-27 | Glaxo Group Ltd | Pyrazolo[3,4-b]pyridine compounds, and their use as pde4 inhibitors |
PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
PE20091552A1 (es) | 2008-02-06 | 2009-10-25 | Glaxo Group Ltd | Farmacoforos duales - antagonistas muscarinicos de pde4 |
WO2009100169A1 (fr) * | 2008-02-06 | 2009-08-13 | Glaxo Group Limited | Pharmacophores duals, antagonistes des récepteurs muscariniques et inhibiteurs de l'activité pde4 |
AR070564A1 (es) | 2008-02-06 | 2010-04-21 | Glaxo Group Ltd | Derivados de 1h-pirazolo[3,4-b]piridin-5-ilo,inhibidores de fosfodiesterasas pde4 y antagonistas de receptores muscarinicos de acetilcolina(machr), utiles en el tratamiento y/o profilaxis de enfermedades respiratorias y alergicas,y composiciones farmaceuticas que los comprenden |
PE20091563A1 (es) | 2008-02-06 | 2009-11-05 | Glaxo Group Ltd | Farmacoforos duales - antagonistas muscarinicos de pde4 |
GB0806900D0 (en) * | 2008-04-16 | 2008-05-21 | Dow Corning | Fabric care emulsions |
WO2009147187A1 (fr) | 2008-06-05 | 2009-12-10 | Glaxo Group Limited | Dérivés de 4-carboxamide indazole utiles en tant qu'inhibiteurs de p13 kinases |
US8470835B2 (en) | 2009-01-13 | 2013-06-25 | Glaxo Group Limited | Pyrimidinecarboxamide derivatives as inhibitors of Syk kinase |
WO2010102958A1 (fr) | 2009-03-09 | 2010-09-16 | Glaxo Group Limited | 4-oxadiazol-2-yl-indazoles en tant qu'inhibiteurs des p13 kinases |
US8354539B2 (en) | 2009-03-10 | 2013-01-15 | Glaxo Group Limited | Indole derivatives as IKK2 inhibitors |
WO2010106016A1 (fr) | 2009-03-17 | 2010-09-23 | Glaxo Group Limited | Dérivés de pyrimidine utilisés comme inhibiteurs de ltk |
ES2404156T3 (es) * | 2009-04-13 | 2013-05-24 | Vanangamudi Subramaniam SULUR | Una crema medicinal con ácido fusídico hecha utilizando fusidato de sodio e incorporando un biopolímero y el proceso para hacerla |
ME02900B (fr) | 2009-04-30 | 2018-04-20 | Glaxo Group Ltd | Nouveaux composés |
JP2013512880A (ja) | 2009-12-03 | 2013-04-18 | グラクソ グループ リミテッド | Pi3−キナーゼ阻害剤としてのインダゾール誘導体 |
EP2507226A1 (fr) | 2009-12-03 | 2012-10-10 | Glaxo Group Limited | Nouveaux composés |
JP2013512879A (ja) | 2009-12-03 | 2013-04-18 | グラクソ グループ リミテッド | Pi3キナーゼの阻害剤としてのベンズピラゾール誘導体 |
WO2011110575A1 (fr) | 2010-03-11 | 2011-09-15 | Glaxo Group Limited | Dérivés de 2-[2-(benzo- ou pyrido-)thiazolylamino]-6- aminopyridine, utiles dans le traitement de maladies respiratoires, allergiques ou inflammatoires |
ES2602972T3 (es) | 2010-09-08 | 2017-02-23 | Glaxosmithkline Intellectual Property Development Limited | Derivados de indazol para su uso en el tratamiento de infección por virus de la gripe |
PT2614058E (pt) | 2010-09-08 | 2015-10-27 | Glaxosmithkline Ip Dev Ltd | Polimorfos e sais de n-[5-[4-(5-{[(2r,6s)-2,6-dimetil-4- morfolinil]metil}-1,3-oxazol-2-il)-1h-indazol-6-il]-2- (metiloxi)-3-piridinil]metanossulfonamida |
WO2012035055A1 (fr) | 2010-09-17 | 2012-03-22 | Glaxo Group Limited | Nouveaux composés |
GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
KR102142162B1 (ko) | 2012-08-27 | 2020-09-14 | 에이비 엘렉트로룩스 | 로봇 위치 선정 시스템 |
KR102118769B1 (ko) | 2013-04-15 | 2020-06-03 | 에이비 엘렉트로룩스 | 로봇 진공 청소기 |
WO2014169944A1 (fr) | 2013-04-15 | 2014-10-23 | Aktiebolaget Electrolux | Dispositif de nettoyage sous vide robotisé avec brosse latérale saillante |
US9011934B2 (en) | 2013-06-14 | 2015-04-21 | SatisPharma, LLC | Multi-purpose anti-itch treatment |
EP3057587A1 (fr) | 2013-10-17 | 2016-08-24 | GlaxoSmithKline Intellectual Property Development Limited | Inhibiteur de pi3k pour le traitement d'une maladie respiratoire |
JP6475707B2 (ja) | 2013-10-17 | 2019-02-27 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 呼吸器疾患の治療のためのpi3k阻害剤 |
ES2656664T3 (es) | 2013-12-19 | 2018-02-28 | Aktiebolaget Electrolux | Dispositivo robótico de limpieza con función de registro del perímetro |
JP6494118B2 (ja) | 2013-12-19 | 2019-04-03 | アクチエボラゲット エレクトロルックス | 障害物の乗り上げの検出に伴うロボット掃除機の制御方法、並びに、当該方法を有するロボット掃除機、プログラム、及びコンピュータ製品 |
EP3082541B1 (fr) | 2013-12-19 | 2018-04-04 | Aktiebolaget Electrolux | Contrôle de la vitesse des brosses latérales en rotation |
CN105793790B (zh) | 2013-12-19 | 2022-03-04 | 伊莱克斯公司 | 优先化清洁区域 |
CN105792721B (zh) | 2013-12-19 | 2020-07-21 | 伊莱克斯公司 | 以螺旋样式移动的带侧刷的机器人真空吸尘器 |
CN105813526B (zh) | 2013-12-19 | 2021-08-24 | 伊莱克斯公司 | 机器人清扫装置以及用于地标识别的方法 |
CN105849660B (zh) | 2013-12-19 | 2020-05-08 | 伊莱克斯公司 | 机器人清扫装置 |
KR102116595B1 (ko) | 2013-12-20 | 2020-06-05 | 에이비 엘렉트로룩스 | 먼지통 |
PE20170185A1 (es) | 2014-05-12 | 2017-04-01 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmaceuticas para tratar enfermedades infecciosas |
ES2681802T3 (es) | 2014-07-10 | 2018-09-17 | Aktiebolaget Electrolux | Método para detectar un error de medición en un dispositivo de limpieza robotizado |
EP3190938A1 (fr) | 2014-09-08 | 2017-07-19 | Aktiebolaget Electrolux | Aspirateur robotisé |
JP6443897B2 (ja) | 2014-09-08 | 2018-12-26 | アクチエボラゲット エレクトロルックス | ロボット真空掃除機 |
US9452178B1 (en) | 2014-10-22 | 2016-09-27 | SatisPharma, LLC | Acne formulations, treatments, and pressure sensitive patches for delivery of acne formulations |
US10877484B2 (en) | 2014-12-10 | 2020-12-29 | Aktiebolaget Electrolux | Using laser sensor for floor type detection |
EP3229983B1 (fr) | 2014-12-12 | 2019-02-20 | Aktiebolaget Electrolux | Brosse latérale et appareil de nettoyage robotique |
CN106998984B (zh) | 2014-12-16 | 2021-07-27 | 伊莱克斯公司 | 用于机器人清洁设备的清洁方法 |
JP6879478B2 (ja) | 2014-12-16 | 2021-06-02 | アクチエボラゲット エレクトロルックス | ロボット掃除機のための経験ベースロードマップ |
WO2016165772A1 (fr) | 2015-04-17 | 2016-10-20 | Aktiebolaget Electrolux | Dispositif de nettoyage robotique et procédé de commande de dispositif de nettoyage robotique |
EP3344104B1 (fr) | 2015-09-03 | 2020-12-30 | Aktiebolaget Electrolux | Système de dispositifs de nettoyage robotisés |
SI3359541T1 (sl) * | 2015-10-09 | 2021-01-29 | Abbvie Overseas S.A R.L. | N-sulfonirani pirazolo(3,4 b)piridin-6-karboksamidi in postopki uporabe |
GB201602527D0 (en) | 2016-02-12 | 2016-03-30 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
EP3430424B1 (fr) | 2016-03-15 | 2021-07-21 | Aktiebolaget Electrolux | Dispositif de nettoyage robotique et procédé au niveau du dispositif de nettoyage robotique pour effectuer une détection de falaise |
EP3454707B1 (fr) | 2016-05-11 | 2020-07-08 | Aktiebolaget Electrolux | Robot de nettoyage |
EP3497100A1 (fr) | 2016-08-08 | 2019-06-19 | GlaxoSmithKline Intellectual Property Development Limited | Composés chimiques |
GB201706102D0 (en) | 2017-04-18 | 2017-05-31 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
KR20220025250A (ko) | 2017-06-02 | 2022-03-03 | 에이비 엘렉트로룩스 | 로봇 청소 장치 전방의 표면의 레벨차를 검출하는 방법 |
GB201712081D0 (en) | 2017-07-27 | 2017-09-13 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
JP6989210B2 (ja) | 2017-09-26 | 2022-01-05 | アクチエボラゲット エレクトロルックス | ロボット清掃デバイスの移動の制御 |
KR102034538B1 (ko) * | 2017-11-28 | 2019-10-21 | 주식회사한국파마 | Jak 저해제 화합물, 및 이의 제조방법 |
CN111875594A (zh) * | 2020-07-21 | 2020-11-03 | 中国药科大学 | 具有磷酸二酯酶4b抑制活性的吲唑杂环类化合物 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833594A (en) * | 1971-08-05 | 1974-09-03 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine carboxylic acids and esters |
US3925388A (en) * | 1971-08-05 | 1975-12-09 | Squibb & Sons Inc | 4-Piperazino-{8 3,4-b{9 pyridine-5-carboxylic acids and esters |
BE787249A (fr) | 1971-08-05 | 1973-02-05 | Squibb & Sons Inc | Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation |
US3856799A (en) | 1971-08-05 | 1974-12-24 | Squibb & Sons Inc | Intermediates for production of amino derivatives of pyrazolopyridine carboxylic acids and esters |
CA1003419A (en) | 1971-11-23 | 1977-01-11 | Theodor Denzel | Process for the production of pyrazolo (3,4-b) pyridines |
US3840546A (en) | 1972-11-15 | 1974-10-08 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine carboxamides |
US3979399A (en) | 1972-11-15 | 1976-09-07 | E. R. Squibb & Sons, Inc. | Amino derivatives of pyrazolopyridine carboxamides |
US3833598A (en) * | 1972-12-29 | 1974-09-03 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine-6-carboxylic acids and esters |
US4115394A (en) * | 1974-05-06 | 1978-09-19 | E. R. Squibb & Sons, Inc. | Amino derivatives of 6-phenylpyrazolo[3,4-b]pyridines |
US4364948A (en) | 1981-09-28 | 1982-12-21 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine compounds |
GB8425104D0 (en) | 1984-10-04 | 1984-11-07 | Ici America Inc | Amide derivatives |
US5547954A (en) * | 1994-05-26 | 1996-08-20 | Fmc Corporation | 2,4-Diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides |
US5593997A (en) | 1995-05-23 | 1997-01-14 | Pfizer Inc. | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors |
US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
DE60026155T2 (de) | 1999-09-30 | 2006-08-10 | Neurogen Corp., Branford | Einige alkylendiamin-substituierte heterocyclen |
GB9929685D0 (en) | 1999-12-15 | 2000-02-09 | Merck Sharp & Dohme | Therapeutic agents |
JP2002020386A (ja) * | 2000-07-07 | 2002-01-23 | Ono Pharmaceut Co Ltd | ピラゾロピリジン誘導体 |
US6670364B2 (en) * | 2001-01-31 | 2003-12-30 | Telik, Inc. | Antagonists of MCP-1 function and methods of use thereof |
MXPA03007134A (es) | 2001-02-08 | 2004-10-15 | Memory Pharm Corp | Trifluorometilpurinas como inhibidores de fosfodiesterasa 4. |
US6677365B2 (en) | 2001-04-03 | 2004-01-13 | Telik, Inc. | Antagonists of MCP-1 function and methods of use thereof |
US20050043319A1 (en) | 2001-08-14 | 2005-02-24 | Exonhit Therapeutics Sa | Molecular target of neurotoxicity |
FR2828693B1 (fr) | 2001-08-14 | 2004-06-18 | Exonhit Therapeutics Sa | Nouvelle cible moleculaire de la neurotoxicite |
GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
CN100387598C (zh) * | 2002-09-16 | 2008-05-14 | 葛兰素集团有限公司 | 吡唑并[3,4-b]吡啶化合物及其作为磷酸二酯酶抑制剂的用途 |
US7117650B2 (en) * | 2002-12-09 | 2006-10-10 | Forrest Dockery | Hanger system |
CA2557004A1 (fr) * | 2003-12-19 | 2005-06-30 | Glaxo Group Limited | Composes pyrazolo [3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de la phosphodiesterase |
GB0405937D0 (en) | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
WO2005090354A1 (fr) * | 2004-03-16 | 2005-09-29 | Glaxo Group Limited | Composes de pyrazolo[3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de pde4 |
GB0405933D0 (en) | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
-
2005
- 2005-03-15 WO PCT/GB2005/000987 patent/WO2005090354A1/fr active Application Filing
- 2005-03-15 JP JP2007503404A patent/JP2007529486A/ja active Pending
- 2005-03-15 RU RU2006132684/04A patent/RU2378274C2/ru not_active IP Right Cessation
- 2005-03-15 AU AU2005223351A patent/AU2005223351A1/en not_active Abandoned
- 2005-03-15 US US10/598,973 patent/US20080275078A1/en not_active Abandoned
- 2005-03-15 EP EP05718039A patent/EP1740590A1/fr not_active Withdrawn
- 2005-03-15 BR BRPI0508843-7A patent/BRPI0508843A/pt not_active IP Right Cessation
- 2005-03-15 CA CA002559629A patent/CA2559629A1/fr not_active Abandoned
- 2005-03-15 US US10/598,838 patent/US7709497B2/en not_active Expired - Fee Related
- 2005-03-15 KR KR1020067021438A patent/KR20060130744A/ko not_active Application Discontinuation
- 2005-03-15 JP JP2007503306A patent/JP2007529464A/ja active Pending
- 2005-03-15 EP EP05716291A patent/EP1735314A1/fr not_active Withdrawn
- 2005-03-15 WO PCT/EP2005/003038 patent/WO2005090352A1/fr active Application Filing
- 2005-03-16 AR ARP050101028A patent/AR048175A1/es not_active Application Discontinuation
- 2005-03-16 PE PE2005000299A patent/PE20060078A1/es not_active Application Discontinuation
- 2005-03-16 TW TW094108054A patent/TW200602051A/zh unknown
-
2006
- 2006-09-11 IL IL178011A patent/IL178011A0/en unknown
- 2006-10-02 NO NO20064450A patent/NO20064450L/no not_active Application Discontinuation
- 2006-10-13 MA MA29385A patent/MA28531B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
IL178011A0 (en) | 2006-12-31 |
AU2005223351A1 (en) | 2005-09-29 |
PE20060078A1 (es) | 2006-03-10 |
NO20064450L (no) | 2006-11-14 |
WO2005090352A1 (fr) | 2005-09-29 |
KR20060130744A (ko) | 2006-12-19 |
WO2005090354A1 (fr) | 2005-09-29 |
EP1740590A1 (fr) | 2007-01-10 |
AR048175A1 (es) | 2006-04-05 |
US7709497B2 (en) | 2010-05-04 |
RU2378274C2 (ru) | 2010-01-10 |
EP1735314A1 (fr) | 2006-12-27 |
JP2007529486A (ja) | 2007-10-25 |
JP2007529464A (ja) | 2007-10-25 |
TW200602051A (en) | 2006-01-16 |
US20080275078A1 (en) | 2008-11-06 |
BRPI0508843A (pt) | 2007-08-28 |
US20070280971A1 (en) | 2007-12-06 |
RU2006132684A (ru) | 2008-04-27 |
CA2559629A1 (fr) | 2005-09-29 |
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