MA26595A1 - Composes hypolipidemiants de benzothiazepine - Google Patents
Composes hypolipidemiants de benzothiazepineInfo
- Publication number
- MA26595A1 MA26595A1 MA25421A MA25421A MA26595A1 MA 26595 A1 MA26595 A1 MA 26595A1 MA 25421 A MA25421 A MA 25421A MA 25421 A MA25421 A MA 25421A MA 26595 A1 MA26595 A1 MA 26595A1
- Authority
- MA
- Morocco
- Prior art keywords
- hypolipidemian
- benzothiazepine
- compounds
- hypolipidemian compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9800428.6A GB9800428D0 (en) | 1998-01-10 | 1998-01-10 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26595A1 true MA26595A1 (fr) | 2004-12-20 |
Family
ID=10825042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA25421A MA26595A1 (fr) | 1998-01-10 | 1999-01-07 | Composes hypolipidemiants de benzothiazepine |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6465451B1 (fr) |
| EP (1) | EP1045840A1 (fr) |
| JP (1) | JP2002500220A (fr) |
| KR (1) | KR20010033988A (fr) |
| CN (1) | CN1292785A (fr) |
| AP (1) | AP2000001860A0 (fr) |
| AR (1) | AR014261A1 (fr) |
| AU (1) | AU2515599A (fr) |
| BR (1) | BR9906799A (fr) |
| CA (1) | CA2317651A1 (fr) |
| CO (1) | CO4820391A1 (fr) |
| EA (1) | EA200000623A1 (fr) |
| GB (1) | GB9800428D0 (fr) |
| HR (1) | HRP20000468A2 (fr) |
| HU (1) | HUP0201343A3 (fr) |
| ID (1) | ID25495A (fr) |
| IL (1) | IL137040A0 (fr) |
| IS (1) | IS5551A (fr) |
| MA (1) | MA26595A1 (fr) |
| NO (1) | NO20003514L (fr) |
| NZ (1) | NZ505453A (fr) |
| PE (1) | PE20000179A1 (fr) |
| PL (1) | PL341672A1 (fr) |
| SK (1) | SK10242000A3 (fr) |
| TR (1) | TR200001816T2 (fr) |
| WO (1) | WO1999035135A1 (fr) |
| ZA (1) | ZA9981B (fr) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010102964A (ko) * | 1998-12-23 | 2001-11-17 | 윌리암스 로저 에이 | 심장혈관 징후를 위한 회장 담즙산 수송 억제인자 및피브린산 유도체의 조합물 |
| SE0000772D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
| AU2001247331A1 (en) * | 2000-03-10 | 2001-09-24 | Pharmacia Corporation | Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders |
| US20020183307A1 (en) * | 2000-07-26 | 2002-12-05 | Tremont Samuel J. | Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake |
| SE0003766D0 (sv) * | 2000-10-18 | 2000-10-18 | Astrazeneca Ab | Novel formulation |
| EG26979A (en) * | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
| GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
| GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| ATE349214T1 (de) | 2001-09-08 | 2007-01-15 | Astrazeneca Ab | Benzothiazepin und benzothiadiazepin derivative mit hemmender wirkung auf den säuretransport in den gallengängen zur behandlung von hyperlipidaemia |
| GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
| GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
| FR2849024B1 (fr) * | 2002-12-20 | 2007-11-02 | Aventis Pharma Sa | Nouveaux composes chiraux derives d'esters de l'acide hexanoique, procede et intermediaires de preparation, utilisation a la synthese de l'acide 2-(bromomethyl)2-ethyl hexanoique chiral |
| GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| CA2744817C (fr) * | 2008-11-26 | 2020-07-07 | Satiogen Pharmaceuticals, Inc. | Inhibiteurs de recyclage de l'acide biliaire pour le traitement de l'obesite et du diabete |
| ES2552657T3 (es) | 2010-05-26 | 2015-12-01 | Satiogen Pharmaceuticals, Inc. | Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias |
| CA2815749C (fr) | 2010-11-08 | 2019-12-03 | Albireo Ab | Inhibiteurs ibat pour le traitement de maladies du foie |
| CN105287604B (zh) | 2010-11-08 | 2019-07-09 | 阿尔比里奥公司 | 含ibat抑制剂和胆汁酸结合剂的药物组合 |
| EA201891154A1 (ru) | 2011-10-28 | 2019-02-28 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
| US20130108573A1 (en) | 2011-10-28 | 2013-05-02 | Lumena Pharmaceuticals, Inc. | Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease |
| WO2014144485A1 (fr) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Inhibiteurs de recyclage d'acide biliaire pour le traitement de l'œsophage de barrett et du reflux gastroœsophagien pathologique |
| JP2016514684A (ja) | 2013-03-15 | 2016-05-23 | ルメナ ファーマシューティカルズ エルエルシー | 原発性硬化性胆管炎および炎症性腸疾患の処置のための胆汁酸再循環阻害剤 |
| JO3301B1 (ar) | 2013-04-26 | 2018-09-16 | Albireo Ab | تعديلات بلورية على إيلوبيكسيبات |
| CA2952406A1 (fr) | 2014-06-25 | 2015-12-30 | Ea Pharma Co., Ltd. | Preparation solide et procede d'inhibition ou d'attenuation de coloration de celle-ci |
| EP3012252A1 (fr) | 2014-10-24 | 2016-04-27 | Ferring BV | Formes crystallines d'Elobixibat |
| US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| EP3413878B1 (fr) | 2016-02-09 | 2021-04-14 | Albireo AB | Formulation orale de cholestyramine et utilisation associée |
| US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
| US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| CN108601744B (zh) | 2016-02-09 | 2022-01-04 | 阿尔比里奥公司 | 口服考来烯胺制剂及其用途 |
| CA3071182A1 (fr) | 2017-08-09 | 2019-02-14 | Albireo Ab | Pastilles de cholestyramine, formulations orales de cholestyramine et leur utilisation |
| EP3664781A1 (fr) | 2017-08-09 | 2020-06-17 | Albireo AB | Granules de cholestyramine, formulations orales de cholestyramine et leur utilisation |
| US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| CA3100113A1 (fr) | 2018-06-05 | 2019-12-12 | Albireo Ab | Composes de benzothia(di)azepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| AU2019290337B2 (en) | 2018-06-20 | 2023-01-12 | Albireo Ab | Crystal modifications of odevixibat |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| JP7504109B2 (ja) | 2019-02-06 | 2024-06-21 | アルビレオ・アクチボラグ | ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
| US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
| WO2020161216A1 (fr) | 2019-02-06 | 2020-08-13 | Albireo Ab | Composés de benzothiazépine et leur utilisation en tant que modulateurs de l'acide biliaire |
| JP2022519905A (ja) | 2019-02-12 | 2022-03-25 | ミルム ファーマシューティカルズ インコーポレイテッド | 胆汁酸塩排出ポンプ欠損症の患者における遺伝子型およびａｓｂｔｉに対する用量依存的反応 |
| AR120676A1 (es) | 2019-12-04 | 2022-03-09 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como ácido biliar |
| AR120674A1 (es) | 2019-12-04 | 2022-03-09 | Albireo Ab | Compuestos de benzotiazepina y su uso como ácido biliar |
| CA3158184A1 (fr) | 2019-12-04 | 2021-08-10 | Albireo Ab | Composes de benzothiadiazepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
| CN114786772B (zh) * | 2019-12-04 | 2024-04-09 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
| PE20230234A1 (es) * | 2019-12-04 | 2023-02-07 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como moduladores del acido biliar |
| CA3158181A1 (fr) | 2019-12-04 | 2021-06-10 | Albireo Ab | Composes de benzothia(di)azepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| AR120683A1 (es) | 2019-12-04 | 2022-03-09 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como ácido biliar |
| TW202134221A (zh) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | 苯并噻二氮呯化合物及其作為膽酸調節劑之用途 |
| CN114786773A (zh) * | 2019-12-04 | 2022-07-22 | 阿尔比里奥公司 | 苯并硫杂氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
| PT4069360T (pt) | 2019-12-04 | 2024-03-06 | Albireo Ab | Compostos de benzotia(di)azepina e a sua utilização como moduladores de ácido biliar |
| EP4188541A1 (fr) | 2020-08-03 | 2023-06-07 | Albireo AB | Composés de benzothia(di)azepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| JP2023549226A (ja) | 2020-11-12 | 2023-11-22 | アルビレオ エービー | 進行性家族性肝内胆汁うっ滞症（ｐｆｉｃ）を処置するためのオデビキシバット |
| EP4255565A1 (fr) * | 2020-12-04 | 2023-10-11 | Albireo AB | Composés de benzothia(di)azepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| US20230398125A1 (en) | 2022-06-09 | 2023-12-14 | Albireo Ab | Treating hepatitis |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004534A1 (fr) | 1993-08-06 | 1995-02-16 | Smithkline Beecham Corporation | Antagonistes du recepteur de l'endotheline |
| ZA956647B (en) | 1994-08-10 | 1997-02-10 | Wellcome Found | Hypolipidaemic compounds. |
| GB9423172D0 (en) * | 1994-11-17 | 1995-01-04 | Wellcom Foundation The Limited | Hypolipidemic benzothiazepines |
-
1998
- 1998-01-10 GB GBGB9800428.6A patent/GB9800428D0/en not_active Ceased
-
1999
- 1999-01-06 PE PE1999000007A patent/PE20000179A1/es not_active Application Discontinuation
- 1999-01-06 ZA ZA9900081A patent/ZA9981B/xx unknown
- 1999-01-06 AR ARP990100035A patent/AR014261A1/es unknown
- 1999-01-07 HU HU0201343A patent/HUP0201343A3/hu unknown
- 1999-01-07 CN CN998036447A patent/CN1292785A/zh active Pending
- 1999-01-07 NZ NZ505453A patent/NZ505453A/xx unknown
- 1999-01-07 SK SK1024-2000A patent/SK10242000A3/sk unknown
- 1999-01-07 MA MA25421A patent/MA26595A1/fr unknown
- 1999-01-07 IL IL13704099A patent/IL137040A0/xx unknown
- 1999-01-07 AP APAP/P/2000/001860A patent/AP2000001860A0/en unknown
- 1999-01-07 BR BR9906799-4A patent/BR9906799A/pt not_active IP Right Cessation
- 1999-01-07 EP EP99904742A patent/EP1045840A1/fr not_active Withdrawn
- 1999-01-07 PL PL99341672A patent/PL341672A1/xx not_active Application Discontinuation
- 1999-01-07 KR KR1020007007581A patent/KR20010033988A/ko not_active Application Discontinuation
- 1999-01-07 WO PCT/EP1999/000021 patent/WO1999035135A1/fr not_active Application Discontinuation
- 1999-01-07 AU AU25155/99A patent/AU2515599A/en not_active Abandoned
- 1999-01-07 JP JP2000527536A patent/JP2002500220A/ja active Pending
- 1999-01-07 EA EA200000623A patent/EA200000623A1/ru unknown
- 1999-01-07 CA CA002317651A patent/CA2317651A1/fr not_active Abandoned
- 1999-01-07 TR TR2000/01816T patent/TR200001816T2/xx unknown
- 1999-01-07 ID IDW20001337A patent/ID25495A/id unknown
- 1999-01-07 US US09/582,907 patent/US6465451B1/en not_active Expired - Fee Related
- 1999-01-08 CO CO99001036A patent/CO4820391A1/es unknown
-
2000
- 2000-06-27 IS IS5551A patent/IS5551A/is unknown
- 2000-07-07 NO NO20003514A patent/NO20003514L/no not_active Application Discontinuation
- 2000-07-10 HR HR20000468A patent/HRP20000468A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2515599A (en) | 1999-07-26 |
| CO4820391A1 (es) | 1999-07-28 |
| NO20003514D0 (no) | 2000-07-07 |
| SK10242000A3 (sk) | 2001-02-12 |
| WO1999035135A1 (fr) | 1999-07-15 |
| TR200001816T2 (tr) | 2000-11-21 |
| NZ505453A (en) | 2002-11-26 |
| AR014261A1 (es) | 2001-02-07 |
| JP2002500220A (ja) | 2002-01-08 |
| US6465451B1 (en) | 2002-10-15 |
| CA2317651A1 (fr) | 1999-07-15 |
| KR20010033988A (ko) | 2001-04-25 |
| PE20000179A1 (es) | 2000-03-16 |
| EP1045840A1 (fr) | 2000-10-25 |
| HRP20000468A2 (en) | 2000-10-31 |
| PL341672A1 (en) | 2001-04-23 |
| ZA9981B (en) | 2000-07-06 |
| GB9800428D0 (en) | 1998-03-04 |
| IS5551A (is) | 2000-06-27 |
| AP2000001860A0 (en) | 2000-09-30 |
| BR9906799A (pt) | 2000-10-10 |
| HUP0201343A2 (hu) | 2003-06-28 |
| EA200000623A1 (ru) | 2001-04-23 |
| CN1292785A (zh) | 2001-04-25 |
| HUP0201343A3 (en) | 2003-08-28 |
| IL137040A0 (en) | 2001-06-14 |
| ID25495A (id) | 2000-10-05 |
| NO20003514L (no) | 2000-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA26595A1 (fr) | Composes hypolipidemiants de benzothiazepine | |
| PT945132E (pt) | Composicao de ibuprofeno | |
| ID27092A (id) | Pembuatan ftalat anhidrida | |
| FR09C0030I2 (fr) | Composes thrombopoietiques | |
| IS2325B (is) | Örgerðar samsetningar epleróns | |
| PT1032396E (pt) | Esterilizacao de glucocorticoesteroides | |
| DE69907405D1 (de) | Optischer mehrkomponentenkörper | |
| ATE229954T1 (de) | Betacarbolinverbindungen | |
| PT1161420E (pt) | Fungicidas de pirazol-carboxanilidas | |
| PT930302E (pt) | Derivados de benzo-sulfona | |
| ID28266A (id) | Senyawa-senyawa amidin | |
| PT1104422E (pt) | Derivados de fenilxantina | |
| PT1119430E (pt) | Fresa | |
| NO20011745L (no) | Forbindelser | |
| EE200100135A (et) | EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid | |
| NO20005006L (no) | Kalsilytiske forbindelser | |
| PT928790E (pt) | Derivados de tiazolo | |
| PT1056716E (pt) | Derivados de ciclo-hexanodiolo | |
| NO20006662L (no) | Fluorfenylresin-forbindelser | |
| ID28032A (id) | TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 | |
| DK1155050T3 (da) | Fremstilling af polyolefin | |
| FI980222A0 (fi) | Stycke av isoleringsaemne med en genomgaoende primaerstroemledning | |
| PT1060183E (pt) | Derivados de 5'-desoxicitidina | |
| PT1123283E (pt) | Derivados de tiazole | |
| DE59909114D1 (de) | Armschiene |