EE200100135A - EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid - Google Patents

EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid

Info

Publication number
EE200100135A
EE200100135A EEP200100135A EEP200100135A EE200100135A EE 200100135 A EE200100135 A EE 200100135A EE P200100135 A EEP200100135 A EE P200100135A EE P200100135 A EEP200100135 A EE P200100135A EE 200100135 A EE200100135 A EE 200100135A
Authority
EE
Estonia
Prior art keywords
eto2c
aze
cgl
pab
crystalline forms
Prior art date
Application number
EEP200100135A
Other languages
English (en)
Inventor
Edvardsson Daniel
Hedstr�m Lena
Lundblad Anita
Pettersson Ursula
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200100135A publication Critical patent/EE200100135A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EEP200100135A 1998-09-03 1999-09-02 EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid EE200100135A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802974A SE9802974D0 (sv) 1998-09-03 1998-09-03 New crystalline forms
PCT/SE1999/001514 WO2000014110A1 (en) 1998-09-03 1999-09-02 CRYSTALLINE FORMS OF EtO2C-CH2-(R)Cgl-Aze-Pab-OH

Publications (1)

Publication Number Publication Date
EE200100135A true EE200100135A (et) 2002-06-17

Family

ID=20412468

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100135A EE200100135A (et) 1998-09-03 1999-09-02 EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid

Country Status (39)

Country Link
US (5) US6225287B1 (et)
EP (1) EP1107980B1 (et)
JP (2) JP3493341B2 (et)
KR (1) KR100629825B1 (et)
CN (1) CN1204143C (et)
AP (1) AP1520A (et)
AR (1) AR029312A1 (et)
AT (1) ATE231521T1 (et)
AU (1) AU763421B2 (et)
BG (1) BG105384A (et)
BR (1) BR9913464A (et)
CA (1) CA2341259A1 (et)
CU (1) CU23015A3 (et)
CZ (1) CZ2001775A3 (et)
DE (1) DE69905054T2 (et)
DK (1) DK1107980T3 (et)
EA (1) EA003264B1 (et)
EE (1) EE200100135A (et)
ES (1) ES2192101T3 (et)
HK (1) HK1034721A1 (et)
HR (1) HRP20010132B1 (et)
HU (1) HUP0104330A2 (et)
ID (1) ID28779A (et)
IL (1) IL141433A0 (et)
IS (1) IS1942B (et)
MY (1) MY121394A (et)
NO (1) NO20011083L (et)
NZ (2) NZ524486A (et)
OA (1) OA11908A (et)
PL (1) PL346544A1 (et)
SA (1) SA99200682B1 (et)
SE (1) SE9802974D0 (et)
SK (1) SK2802001A3 (et)
TR (1) TR200100700T2 (et)
TW (1) TWI247013B (et)
UA (1) UA66869C2 (et)
WO (1) WO2000014110A1 (et)
YU (1) YU17301A (et)
ZA (1) ZA200101763B (et)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802974D0 (sv) 1998-09-03 1998-09-03 Astra Ab New crystalline forms
SE9900070D0 (sv) 1999-01-13 1999-01-13 Astra Ab New use
SE9902550D0 (sv) 1999-07-02 1999-07-02 Astra Ab New crystalline forms
US20020115603A1 (en) * 2000-06-22 2002-08-22 Chiron Corporation Methods and compositions for the treatment of peripheral artery disease
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
TWI286139B (en) * 2000-10-12 2007-09-01 Chugai Pharmaceutical Co Ltd Erythromycin derivative having novel crystal structures and processes for their production
AR035216A1 (es) * 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
AR034517A1 (es) * 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
AU2003219039A1 (en) 2002-03-11 2003-09-22 Curacyte Ag Urokinase inhibitors, production and use thereof
SE0201659D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
DE10301300B4 (de) 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
US7781424B2 (en) * 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
DE10342108A1 (de) * 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
WO2005031397A2 (en) * 2003-09-26 2005-04-07 Zetetic Institute Catoptric and catadioptric imaging systems with pellicle and aperture-array beam-splitters and non-adaptive and adaptive catoptric surfaces
US20050209211A1 (en) * 2004-03-16 2005-09-22 Devalina Law Trihemihydrate, anhydrate and novel hydrate forms of Cefdinir
WO2005091696A1 (fr) * 2004-03-29 2005-10-06 Quanta Display Inc. Structure a cadres pour module retroeclaire
US7524354B2 (en) * 2005-07-07 2009-04-28 Research Foundation Of State University Of New York Controlled synthesis of highly monodispersed gold nanoparticles
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
TW200827336A (en) * 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
US20090061000A1 (en) * 2007-08-31 2009-03-05 Astrazeneca Ab Pharmaceutical formulation use 030
EP2361572B1 (en) * 2010-02-26 2013-04-17 Biedermann Technologies GmbH & Co. KG Implant for stabilizing bones or vertebrae
US9550585B2 (en) 2014-06-09 2017-01-24 Space Systems/Loral, Llc Highly inclined elliptical orbit de-orbit techniques

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
DE3169094D1 (en) * 1980-11-20 1985-03-28 Beecham Group Plc Secondary amines
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
SE504185C2 (sv) * 1994-11-08 1996-12-02 Astra Ab Lagringsstabil vattenlösning för infusion av trombininhibitorer
TWI238827B (en) * 1995-12-21 2005-09-01 Astrazeneca Ab Prodrugs of thrombin inhibitors
US5830805A (en) * 1996-11-18 1998-11-03 Cornell Research Foundation Electroless deposition equipment or apparatus and method of performing electroless deposition
SE9802974D0 (sv) * 1998-09-03 1998-09-03 Astra Ab New crystalline forms

Also Published As

Publication number Publication date
EP1107980B1 (en) 2003-01-22
US6440939B2 (en) 2002-08-27
HRP20010132B1 (en) 2004-06-30
AP1520A (en) 2005-12-28
IL141433A0 (en) 2002-03-10
US20030017992A1 (en) 2003-01-23
JP3493341B2 (ja) 2004-02-03
UA66869C2 (uk) 2004-06-15
DE69905054T2 (de) 2003-11-06
CN1325406A (zh) 2001-12-05
ZA200101763B (en) 2002-06-03
CZ2001775A3 (cs) 2001-10-17
OA11908A (en) 2006-04-10
AU763421B2 (en) 2003-07-24
BR9913464A (pt) 2001-06-12
MY121394A (en) 2006-01-28
WO2000014110A1 (en) 2000-03-16
TR200100700T2 (tr) 2001-07-23
AP2001002078A0 (en) 2001-03-31
CA2341259A1 (en) 2000-03-16
ATE231521T1 (de) 2003-02-15
AR029312A1 (es) 2003-06-25
HUP0104330A2 (hu) 2002-04-29
HRP20010132A2 (en) 2002-02-28
NZ524486A (en) 2004-10-29
PL346544A1 (en) 2002-02-11
US20060287249A1 (en) 2006-12-21
US20050153901A1 (en) 2005-07-14
NZ510070A (en) 2003-04-29
NO20011083D0 (no) 2001-03-02
TWI247013B (en) 2006-01-11
EA200100194A1 (ru) 2001-10-22
SA99200682B1 (ar) 2006-08-22
US6888007B2 (en) 2005-05-03
JP2004075687A (ja) 2004-03-11
DK1107980T3 (da) 2003-04-22
SK2802001A3 (en) 2001-09-11
EP1107980A1 (en) 2001-06-20
EA003264B1 (ru) 2003-02-27
YU17301A (sh) 2004-05-12
KR20010088795A (ko) 2001-09-28
IS5870A (is) 2001-02-28
KR100629825B1 (ko) 2006-09-29
NO20011083L (no) 2001-05-03
IS1942B (is) 2004-08-13
AU6014799A (en) 2000-03-27
DE69905054D1 (de) 2003-02-27
SE9802974D0 (sv) 1998-09-03
ID28779A (id) 2001-07-05
BG105384A (en) 2001-11-30
US6225287B1 (en) 2001-05-01
US20010023244A1 (en) 2001-09-20
HK1034721A1 (en) 2001-11-02
ES2192101T3 (es) 2003-09-16
CU23015A3 (es) 2005-01-25
JP2002524467A (ja) 2002-08-06
CN1204143C (zh) 2005-06-01
US20050054579A9 (en) 2005-03-10

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