LV5740B4 - Stabilas 4"-dezoksi-4"-epi-metilaminoavermektina Bla/Blb salis - Google Patents

Stabilas 4"-dezoksi-4"-epi-metilaminoavermektina Bla/Blb salis

Info

Publication number
LV5740B4
LV5740B4 LV950265A LV950265A LV5740B4 LV 5740 B4 LV5740 B4 LV 5740B4 LV 950265 A LV950265 A LV 950265A LV 950265 A LV950265 A LV 950265A LV 5740 B4 LV5740 B4 LV 5740B4
Authority
LV
Latvia
Prior art keywords
acid salt
blb
epi
deoxy
stable
Prior art date
Application number
LV950265A
Other languages
English (en)
Latvian (lv)
Other versions
LV5740A4 (lv
Inventor
Raymond Cvetovich
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LV5740A4 publication Critical patent/LV5740A4/xx
Publication of LV5740B4 publication Critical patent/LV5740B4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Silicon Polymers (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
LV950265A 1990-06-28 1995-08-31 Stabilas 4"-dezoksi-4"-epi-metilaminoavermektina Bla/Blb salis LV5740B4 (lv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54522990A 1990-06-28 1990-06-28

Publications (2)

Publication Number Publication Date
LV5740A4 LV5740A4 (lv) 1996-08-20
LV5740B4 true LV5740B4 (lv) 1997-12-20

Family

ID=24175383

Family Applications (1)

Application Number Title Priority Date Filing Date
LV950265A LV5740B4 (lv) 1990-06-28 1995-08-31 Stabilas 4"-dezoksi-4"-epi-metilaminoavermektina Bla/Blb salis

Country Status (21)

Country Link
US (1) US5288710A (fr)
EP (1) EP0465121B1 (fr)
JP (1) JPH0822870B2 (fr)
KR (1) KR100224292B1 (fr)
AT (1) ATE134377T1 (fr)
AU (1) AU641777B2 (fr)
CA (1) CA2045864C (fr)
CY (1) CY1949A (fr)
DE (1) DE69117223T2 (fr)
DK (1) DK0465121T3 (fr)
ES (1) ES2084110T3 (fr)
FI (1) FI97890C (fr)
GR (1) GR3019067T3 (fr)
HK (1) HK157096A (fr)
IE (1) IE71175B1 (fr)
IL (1) IL98599A (fr)
LV (1) LV5740B4 (fr)
NO (2) NO2001007I2 (fr)
NZ (1) NZ238705A (fr)
PT (1) PT98117B (fr)
ZA (1) ZA914961B (fr)

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AU687062B2 (en) * 1993-05-26 1998-02-19 Commonwealth Scientific And Industrial Research Organisation Controlled release antiparasitic compositions
WO1995005390A1 (fr) * 1993-08-19 1995-02-23 Merck & Co., Inc. FORME CRISTALLINE THERMODYNAMIQUEMENT STABLE D'UN SEL D'ACIDE BENZOÏQUE DE 4'-DESOXY-4'-EPI-METHYLAMINO AVERMECTINE B1a/B1b ET PROCEDES DE PREPARATION DUDIT SEL
US6486195B1 (en) * 1993-08-19 2002-11-26 Merck & Co., Inc. Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
US5362863A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for the preparation of 4"-amino avermectin compounds
CN1915016B (zh) 1995-11-08 2010-12-22 默沙东公司 农药制剂
AU768262B2 (en) * 1995-11-08 2003-12-04 Merck Sharp & Dohme Corp. Pesticidal formulation
WO1997016968A1 (fr) * 1995-11-08 1997-05-15 Merck & Co., Inc. Formulation pesticide
US20050192319A1 (en) * 1996-09-19 2005-09-01 Albert Boeckh Spot-on formulations for combating parasites
US6054140A (en) * 1997-03-21 2000-04-25 Biogenesis S.A. Long acting injectable parasiticidal composition and the process for its preparation
WO1999025187A2 (fr) * 1997-11-14 1999-05-27 Novartis Ag Composition pesticide
BRPI9814318B1 (pt) * 1997-12-23 2017-04-18 Novartis Ag (Novartis Sa) (Novartis Inc ) processo para controle de insetos em culturas de plantas transgênicas úteis expressando a proteína cry1ab
US6486128B1 (en) 1999-04-08 2002-11-26 Schering-Plough Veterinary Corporation Method of using emamectin to treat fish parasites
AR006063A4 (es) * 1999-04-17 1999-08-11 Romario S R L Bandeja termica para pizzas
GB9926887D0 (en) * 1999-11-12 2000-01-12 Novartis Ag Organic compounds
CR6574A (es) * 2001-02-27 2004-10-28 Syngenta Participations Ag Sales de avermectinas substituidas en la posicion 4 con propiedades plaguicidas
EG23124A (en) 2001-02-27 2004-04-28 Syngenta Participations Ag Avermectins substituted in the 4-position having pesticidal properties
JP4701538B2 (ja) 2001-05-21 2011-06-15 住友化学株式会社 農業害虫防除剤組成物
AR036486A1 (es) 2001-08-28 2004-09-15 Syngenta Participations Ag Derivados 4"-desoxi-4"-(s)-amino avermectina, composicion plaguicida, procedimiento para la preparacion de esa composicion, metodo para controlar plagas, y uso de estos derivados para preparar una composicion
DE10203688A1 (de) 2002-01-31 2003-08-07 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207241A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207242A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
MXPA04009101A (es) * 2002-03-22 2004-12-06 Lg Life Sciences Ltd Sal de acido maleico de (2s) -n-{5- [amino(imino) metil]-2 -tienil} metil-1 -{(2r)- 2-[(carboximetil) amino]-3, 3- difenilpropanoil} -2-pirrolidin carboxamida y un proceso para preparacion de la misma.
AR040073A1 (es) 2002-05-07 2005-03-16 Syngenta Participations Ag Derivados de 4''-desoxi-4''-(s)-amido avermectina y su uso como plaguicidas
GB0302308D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302310D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0320176D0 (en) 2003-08-28 2003-10-01 Syngenta Participations Ag Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
US7312248B2 (en) 2004-09-23 2007-12-25 Schering-Plough Animal Health Corporation Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
ATE446677T1 (de) * 2004-11-19 2009-11-15 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h- pyrrol-2-yl) acrylonitril-derivaten
EP1890547A2 (fr) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Controle de parasites chez des animaux a l'aide de derives de n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide et de n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP1849363A1 (fr) * 2006-03-09 2007-10-31 Cheminova A/S Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
TWI422328B (zh) 2006-06-19 2014-01-11 Univ California 結合有殺線蟲之種子塗覆物的生物控制劑
FR2906469B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques chez l'homme
EP2091909A1 (fr) * 2006-12-13 2009-08-26 Schering-Plough Ltd. Promedicaments de florfenicol solubles dans l'eau et analogues
US8044230B2 (en) * 2006-12-13 2011-10-25 Intervet Inc. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
DE102007002872A1 (de) 2007-01-15 2008-07-17 Alpha-Biocare Gmbh Verwendung von Avermectin-Derivaten zur Behandlung gegen Parasiten von Fischen
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
MX2009013748A (es) 2007-06-27 2010-01-26 Du Pont Metodo de control de plagas en animales.
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
EP2321269B1 (fr) * 2008-07-30 2018-09-19 Intervet International B.V. Procede de preparation de composes aminodiol d'oxazoline proteges utiles comme produits intermediaires dans la production de florfenicol
AR075846A1 (es) 2009-03-17 2011-04-27 Organon Nv Sistema de administracion de farmaco de lactona macrociclica.uso. metodo de tratamiento
EP2462125A2 (fr) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Pesticides méso-ioniques
CN102686570A (zh) 2009-08-05 2012-09-19 杜邦公司 介离子杀虫剂
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
UA108881C2 (xx) 2010-05-27 2015-06-25 Кристалічна форма 4-$5-$3-хлор-5-(трифторметил)феніл]-4,5-дигідро-5-(трифторметил)-3-ізоксазоліл]-n-$2-оксо-2-$(2,2,2-трифторетил)аміно]етил]-1-нафталінкарбоксаміду
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
CA2811924C (fr) 2010-10-20 2015-06-16 Galderma S.A. Methode de traitement des hemorroides a l'aide d'un compose de lactone macrocyclique
WO2012087630A1 (fr) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Composés de pyridine et de pyrimidine utilisés pour lutter contre des nuisibles invertébrés
HUE058290T2 (hu) 2010-12-27 2022-07-28 Intervet Int Bv Topikális lokalizált izoxazolin formuláció, amely tartalmaz glikofurolt
WO2012089622A2 (fr) 2010-12-27 2012-07-05 Intervet International B.V. Préparation à base d'isoxazoline pour application topique
BR112014001950B1 (pt) 2011-07-28 2021-01-12 Syngenta Participations Ag métodos para controle de uma praga de nemátodos e para produzir uma planta de soja protegida contra infestação de nemátodos
WO2013158422A1 (fr) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Composés hétérocycliques pour la lutte contre des animaux nuisibles invertébrés
US9643991B2 (en) * 2015-06-08 2017-05-09 Rotam Agrochem International Company Limited Process for preparing a novel crystalline form of emamectin benzoate and use the same
US9409920B1 (en) * 2015-06-08 2016-08-09 Rotam Agrochem International Company Limited Method for purifying emamectin benzoate and compositions comprising the same
CN107344954B (zh) * 2017-08-07 2020-08-11 河北蓝泰化工科技有限公司 增效型甲氨基阿维菌素b1或b2的盐及制备方法和应用
CN108840893A (zh) * 2018-07-01 2018-11-20 李万强 一种甲氨基阿维菌素苯甲酸盐的新晶型及其制备方法
CN108864230B (zh) * 2018-07-26 2021-05-14 河北威远生物化工有限公司 一种有机磷基团取代的阿维菌素衍生物及其制备方法和应用

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US4321361A (en) * 1980-06-12 1982-03-23 Eli Lilly And Company Demycinosyltylosin and process for its production
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US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb

Also Published As

Publication number Publication date
AU7939291A (en) 1992-01-02
ATE134377T1 (de) 1996-03-15
CA2045864C (fr) 2001-11-27
PT98117A (pt) 1993-10-29
JPH05306294A (ja) 1993-11-19
DE69117223D1 (de) 1996-03-28
IE71175B1 (en) 1997-01-29
DE69117223T2 (de) 1996-09-12
IL98599A0 (en) 1992-07-15
EP0465121B1 (fr) 1996-02-21
LV5740A4 (lv) 1996-08-20
NO178339C (no) 1996-03-06
NZ238705A (en) 1993-07-27
CA2045864A1 (fr) 1991-12-29
NO178339B (no) 1995-11-27
GR3019067T3 (en) 1996-05-31
PT98117B (pt) 1998-12-31
AU641777B2 (en) 1993-09-30
HK157096A (en) 1996-08-23
NO912535L (no) 1991-12-30
JPH0822870B2 (ja) 1996-03-06
US5288710A (en) 1994-02-22
IE912251A1 (en) 1992-01-01
KR100224292B1 (ko) 1999-10-15
FI97890C (fi) 1997-03-10
IL98599A (en) 1995-06-29
ES2084110T3 (es) 1996-05-01
FI913137A0 (fi) 1991-06-27
NO2001007I2 (no) 2007-02-26
DK0465121T3 (da) 1996-03-18
FI913137A (fi) 1991-12-29
CY1949A (en) 1991-06-27
EP0465121A1 (fr) 1992-01-08
NO912535D0 (no) 1991-06-27
ZA914961B (en) 1992-07-29
FI97890B (fi) 1996-11-29
KR920000781A (ko) 1992-01-29

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