NO912535L - Fremgangsmaate for fremstilling av stabile salter av 4''-deoksy-4''-epi-metylamino-avermectin b1a/b1b. - Google Patents

Fremgangsmaate for fremstilling av stabile salter av 4''-deoksy-4''-epi-metylamino-avermectin b1a/b1b.

Info

Publication number
NO912535L
NO912535L NO91912535A NO912535A NO912535L NO 912535 L NO912535 L NO 912535L NO 91912535 A NO91912535 A NO 91912535A NO 912535 A NO912535 A NO 912535A NO 912535 L NO912535 L NO 912535L
Authority
NO
Norway
Prior art keywords
acid salt
epi
deoxy
metylamino
avermectin
Prior art date
Application number
NO91912535A
Other languages
English (en)
Other versions
NO178339C (no
NO178339B (no
NO912535D0 (no
Inventor
Raymond Cvetovich
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO912535D0 publication Critical patent/NO912535D0/no
Publication of NO912535L publication Critical patent/NO912535L/no
Priority to NO952511A priority Critical patent/NO300136B1/no
Publication of NO178339B publication Critical patent/NO178339B/no
Publication of NO178339C publication Critical patent/NO178339C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Silicon Polymers (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
NO912535A 1990-06-28 1991-06-27 Stabile salter av 4''-deoksy-4''-epi-metylaminoavermectin B1a/Blb med egenskaper som landbruksinsekticid og preparater inneholdende et slikt salt NO178339C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO952511A NO300136B1 (no) 1990-06-28 1995-06-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive, stabile salter av 4''-deoksy-4''-epi-metylaminoavermectin B1a/B1b

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54522990A 1990-06-28 1990-06-28

Publications (4)

Publication Number Publication Date
NO912535D0 NO912535D0 (no) 1991-06-27
NO912535L true NO912535L (no) 1991-12-30
NO178339B NO178339B (no) 1995-11-27
NO178339C NO178339C (no) 1996-03-06

Family

ID=24175383

Family Applications (2)

Application Number Title Priority Date Filing Date
NO2001007C NO2001007I2 (no) 1990-06-28 1991-06-27 Stabile salter av 4"-deoksy-4"-epimetylaminoavermectin B1a/B1b med egenskaper som landbruksinsekticid og preparater inneholdende et slikt salt
NO912535A NO178339C (no) 1990-06-28 1991-06-27 Stabile salter av 4''-deoksy-4''-epi-metylaminoavermectin B1a/Blb med egenskaper som landbruksinsekticid og preparater inneholdende et slikt salt

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO2001007C NO2001007I2 (no) 1990-06-28 1991-06-27 Stabile salter av 4"-deoksy-4"-epimetylaminoavermectin B1a/B1b med egenskaper som landbruksinsekticid og preparater inneholdende et slikt salt

Country Status (21)

Country Link
US (1) US5288710A (no)
EP (1) EP0465121B1 (no)
JP (1) JPH0822870B2 (no)
KR (1) KR100224292B1 (no)
AT (1) ATE134377T1 (no)
AU (1) AU641777B2 (no)
CA (1) CA2045864C (no)
CY (1) CY1949A (no)
DE (1) DE69117223T2 (no)
DK (1) DK0465121T3 (no)
ES (1) ES2084110T3 (no)
FI (1) FI97890C (no)
GR (1) GR3019067T3 (no)
HK (1) HK157096A (no)
IE (1) IE71175B1 (no)
IL (1) IL98599A (no)
LV (1) LV5740B4 (no)
NO (2) NO2001007I2 (no)
NZ (1) NZ238705A (no)
PT (1) PT98117B (no)
ZA (1) ZA914961B (no)

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AR036486A1 (es) 2001-08-28 2004-09-15 Syngenta Participations Ag Derivados 4"-desoxi-4"-(s)-amino avermectina, composicion plaguicida, procedimiento para la preparacion de esa composicion, metodo para controlar plagas, y uso de estos derivados para preparar una composicion
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AR040073A1 (es) 2002-05-07 2005-03-16 Syngenta Participations Ag Derivados de 4''-desoxi-4''-(s)-amido avermectina y su uso como plaguicidas
GB0302308D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302310D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0320176D0 (en) 2003-08-28 2003-10-01 Syngenta Participations Ag Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
US7312248B2 (en) 2004-09-23 2007-12-25 Schering-Plough Animal Health Corporation Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
ATE446677T1 (de) * 2004-11-19 2009-11-15 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h- pyrrol-2-yl) acrylonitril-derivaten
EP1890547A2 (en) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
TWI422328B (zh) 2006-06-19 2014-01-11 Univ California 結合有殺線蟲之種子塗覆物的生物控制劑
FR2906469B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques chez l'homme
EP2091909A1 (en) * 2006-12-13 2009-08-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
US8044230B2 (en) * 2006-12-13 2011-10-25 Intervet Inc. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
DE102007002872A1 (de) 2007-01-15 2008-07-17 Alpha-Biocare Gmbh Verwendung von Avermectin-Derivaten zur Behandlung gegen Parasiten von Fischen
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
MX2009013748A (es) 2007-06-27 2010-01-26 Du Pont Metodo de control de plagas en animales.
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
EP2321269B1 (en) * 2008-07-30 2018-09-19 Intervet International B.V. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
AR075846A1 (es) 2009-03-17 2011-04-27 Organon Nv Sistema de administracion de farmaco de lactona macrociclica.uso. metodo de tratamiento
EP2462125A2 (en) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionic pesticides
CN102686570A (zh) 2009-08-05 2012-09-19 杜邦公司 介离子杀虫剂
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
UA108881C2 (xx) 2010-05-27 2015-06-25 Кристалічна форма 4-$5-$3-хлор-5-(трифторметил)феніл]-4,5-дигідро-5-(трифторметил)-3-ізоксазоліл]-n-$2-оксо-2-$(2,2,2-трифторетил)аміно]етил]-1-нафталінкарбоксаміду
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
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WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
HUE058290T2 (hu) 2010-12-27 2022-07-28 Intervet Int Bv Topikális lokalizált izoxazolin formuláció, amely tartalmaz glikofurolt
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BR112014001950B1 (pt) 2011-07-28 2021-01-12 Syngenta Participations Ag métodos para controle de uma praga de nemátodos e para produzir uma planta de soja protegida contra infestação de nemátodos
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US9643991B2 (en) * 2015-06-08 2017-05-09 Rotam Agrochem International Company Limited Process for preparing a novel crystalline form of emamectin benzoate and use the same
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CN107344954B (zh) * 2017-08-07 2020-08-11 河北蓝泰化工科技有限公司 增效型甲氨基阿维菌素b1或b2的盐及制备方法和应用
CN108840893A (zh) * 2018-07-01 2018-11-20 李万强 一种甲氨基阿维菌素苯甲酸盐的新晶型及其制备方法
CN108864230B (zh) * 2018-07-26 2021-05-14 河北威远生物化工有限公司 一种有机磷基团取代的阿维菌素衍生物及其制备方法和应用

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Also Published As

Publication number Publication date
AU7939291A (en) 1992-01-02
ATE134377T1 (de) 1996-03-15
CA2045864C (en) 2001-11-27
PT98117A (pt) 1993-10-29
JPH05306294A (ja) 1993-11-19
DE69117223D1 (de) 1996-03-28
IE71175B1 (en) 1997-01-29
DE69117223T2 (de) 1996-09-12
IL98599A0 (en) 1992-07-15
EP0465121B1 (en) 1996-02-21
LV5740A4 (lv) 1996-08-20
NO178339C (no) 1996-03-06
NZ238705A (en) 1993-07-27
CA2045864A1 (en) 1991-12-29
LV5740B4 (lv) 1997-12-20
NO178339B (no) 1995-11-27
GR3019067T3 (en) 1996-05-31
PT98117B (pt) 1998-12-31
AU641777B2 (en) 1993-09-30
HK157096A (en) 1996-08-23
JPH0822870B2 (ja) 1996-03-06
US5288710A (en) 1994-02-22
IE912251A1 (en) 1992-01-01
KR100224292B1 (ko) 1999-10-15
FI97890C (fi) 1997-03-10
IL98599A (en) 1995-06-29
ES2084110T3 (es) 1996-05-01
FI913137A0 (fi) 1991-06-27
NO2001007I2 (no) 2007-02-26
DK0465121T3 (da) 1996-03-18
FI913137A (fi) 1991-12-29
CY1949A (en) 1991-06-27
EP0465121A1 (en) 1992-01-08
NO912535D0 (no) 1991-06-27
ZA914961B (en) 1992-07-29
FI97890B (fi) 1996-11-29
KR920000781A (ko) 1992-01-29

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Legal Events

Date Code Title Description
SPCG Granted supplementary protection certificate

Free format text: PRODUCT NAME: EMAMECTIN; NAT. REG. NO/DATE: NO , 99-4254; FIRST REG. NO/DATE: GB , VM 00201/4 20000114

Spc suppl protection certif: 2001007

Filing date: 20010525

Extension date: 20150114

MK1K Patent expired