LUC00014I2 - - Google Patents

Info

Publication number
LUC00014I2
LUC00014I2 LU00014C LUC00014C LUC00014I2 LU C00014 I2 LUC00014 I2 LU C00014I2 LU 00014 C LU00014 C LU 00014C LU C00014 C LUC00014 C LU C00014C LU C00014 I2 LUC00014 I2 LU C00014I2
Authority
LU
Luxembourg
Application number
LU00014C
Original Assignee
Millennium Pharm Inc
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Genentech Inc filed Critical Millennium Pharm Inc
Publication of LUC00014I1 publication Critical patent/LUC00014I1/fr
Publication of LUC00014I2 publication Critical patent/LUC00014I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
LU00014C 2000-04-14 2017-04-11 LUC00014I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55008200A 2000-04-14 2000-04-14
US09/748,960 US20010046496A1 (en) 2000-04-14 2000-12-27 Method of administering an antibody
EP01925028A EP1278543B1 (fr) 2000-04-14 2001-04-13 Methode d'administration d'un anticorps

Publications (2)

Publication Number Publication Date
LUC00014I1 LUC00014I1 (fr) 2017-04-18
LUC00014I2 true LUC00014I2 (fr) 2017-06-19

Family

ID=27069332

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00014C LUC00014I2 (fr) 2000-04-14 2017-04-11

Country Status (16)

Country Link
US (5) US20010046496A1 (fr)
EP (3) EP1278543B1 (fr)
JP (3) JP2003531129A (fr)
AU (1) AU2001251629A1 (fr)
BE (1) BE2017C009I2 (fr)
CA (1) CA2406220C (fr)
CY (3) CY1113489T1 (fr)
DK (2) DK1278543T3 (fr)
ES (2) ES2398096T3 (fr)
FR (1) FR14C0080I2 (fr)
HK (1) HK1054320A1 (fr)
LU (1) LUC00014I2 (fr)
MX (1) MXPA02010059A (fr)
NL (1) NL300702I1 (fr)
PT (1) PT2298348T (fr)
WO (1) WO2001078779A2 (fr)

Families Citing this family (44)

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Publication number Priority date Publication date Assignee Title
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
ATE512163T1 (de) * 2002-02-25 2011-06-15 Elan Pharm Inc Verabreichung von mitteln zur behandlung von entzündungen
GB0210121D0 (en) * 2002-05-02 2002-06-12 Celltech R&D Ltd Biological products
LT1507556T (lt) * 2002-05-02 2016-10-10 Wyeth Holdings Llc Kalicheamicino darinio ir nešiklio konjugatai
CA2552523C (fr) * 2004-01-09 2019-11-26 Pfizer Inc. Anticorps monoclonaux diriges contre la molecule d'adherence cellulaire madcam
ES2911482T3 (es) 2004-09-03 2022-05-19 Genentech Inc Antagonistas anti-beta7 humanizados y usos para los mismos
ATE483732T1 (de) * 2005-07-08 2010-10-15 Pfizer Ltd Madcam-antikörper
RU2008101383A (ru) * 2005-07-11 2009-07-20 Пфайзер Лимитед (GB) НОВАЯ КОМБИНАЦИЯ АНТИMAdCAM-АНТИТЕЛА И ПРОТИВОФИБРОЗНОГО ИНГИБИТОРА КАСПАЗЫ ДЛЯ ЛЕЧЕНИЯ ФИБРОЗА ПЕЧЕНИ
WO2007007152A2 (fr) * 2005-07-11 2007-01-18 Pfizer Limited Anticorps anti-madcam utilises pour le traitement de cancers metastatiques et du chlorome
EP2109460B1 (fr) * 2007-01-11 2016-05-18 Novo Nordisk A/S Anticorps anti-kir, formulations et utilisations de celles-ci
EP2125892A2 (fr) * 2007-03-20 2009-12-02 Millennium Pharmaceuticals, Inc. Acides nucléiques codant une immunoglobuline humanisée qui se lie à l'intégrine a4b7
US20110105724A1 (en) * 2007-08-16 2011-05-05 Stephanie Jane Clegg Novel compounds
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
EP2279004B1 (fr) * 2008-05-16 2015-01-14 F. Hoffmann-La Roche AG Utilisation de biomarqueurs pour évaluer le traitement de troubles inflammatoires gastro-intestinaux avec des antagonistes de l'intégrine bêta7
ES2751946T3 (es) * 2009-03-20 2020-04-02 Amgen Inc Anticuerpo antagonista específico del heterodímero alfa-4-beta-7
EP3578205A1 (fr) 2010-08-06 2019-12-11 ModernaTX, Inc. Compositions pharmaceutiques a base d'acides nucléiques modifiés et leur utilisation medicale
NZ608972A (en) 2010-10-01 2015-09-25 Moderna Therapeutics Inc Engineered nucleic acids and methods of use thereof
US8710200B2 (en) 2011-03-31 2014-04-29 Moderna Therapeutics, Inc. Engineered nucleic acids encoding a modified erythropoietin and their expression
MX354101B (es) * 2011-05-02 2018-02-13 Millennium Pharm Inc FORMULACION PARA ANTICUERPO ANTI -A4ß7.
UA116189C2 (uk) * 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CA2850624A1 (fr) 2011-10-03 2013-04-11 Moderna Therapeutics, Inc. Nucleosides, nucleotides et acides nucleiques modifies, et leurs utilisations
EP2782599B1 (fr) * 2011-11-23 2019-10-16 Amgen Inc. Administration d'un anticorps spécifique hétérodimère anti-alpha-4-bêta-7
CN110201187A (zh) 2011-12-16 2019-09-06 现代泰克斯公司 经修饰的核苷、核苷酸和核酸组合物
EA201992881A3 (ru) * 2012-01-12 2020-12-30 Милленниум Фармасьютикалз, Инк. Композиция анти-47 антитела
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
AU2013243952A1 (en) 2012-04-02 2014-10-30 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
PT2922554T (pt) 2012-11-26 2022-06-28 Modernatx Inc Arn modificado nas porções terminais
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (fr) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucléotides codant des polypeptides de modulation immunitaire
US10323076B2 (en) 2013-10-03 2019-06-18 Modernatx, Inc. Polynucleotides encoding low density lipoprotein receptor
US20170327584A1 (en) 2014-11-26 2017-11-16 Millennium Pharmaceuticals, Inc. Vedolizumab for the Treatment of Fistulizing Crohn's Disease
JP6904905B2 (ja) 2014-12-24 2021-07-21 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 抗α４β７インテグリン抗体による治療の結果の予測
MA43755A (fr) 2016-03-14 2018-11-28 Millennium Pharm Inc Méthodes de traitement ou de prévention d'une maladie du greffon contre l'hôte
CN109071660A (zh) 2016-03-14 2018-12-21 千禧制药公司 预防移植物抗宿主疾病的方法
EP3433275A1 (fr) 2016-03-24 2019-01-30 Millennium Pharmaceuticals, Inc. Procédés pour traiter des événements indésirables gastro-intestinaux d'origine immunitaire dans des traitements oncologiques immunitaires
WO2017165742A1 (fr) 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Procédés de traitement d'événements indésirables liés à l'immunité gastro-intestinale dans des polythérapies anti-ctla4 et anti-pd-1
MA44864A (fr) 2016-05-04 2019-03-13 Icahn School Med Mount Sinai Trithérapie pour le traitement d'une maladie intestinale inflammatoire
CA3027286A1 (fr) 2016-06-12 2017-12-21 Millennium Pharmaceuticals, Inc. Methode de traitement de maladie intestinale inflammatoire
JP7160491B2 (ja) 2017-07-14 2022-10-25 ファイザー インコーポレイティッド ＭＡｄＣＡＭに対する抗体
US20230139938A1 (en) * 2021-09-21 2023-05-04 University Of South Carolina Anti-CCL8 Antibodies and Treatment of Lung Injury by CCL8 Inhibition

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US5403919A (en) * 1987-08-11 1995-04-04 Board Of Trustees Of The Leland Stanford Junior University Stanford University Method to control leukocyte extravasation
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CA2115811A1 (fr) 1993-02-17 1994-08-18 Claus Krebber Methode de selection in vivo de proteines fixatrices de ligands
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US6015662A (en) * 1996-01-23 2000-01-18 Abbott Laboratories Reagents for use as calibrators and controls
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
EP2314625B1 (fr) 1996-12-03 2014-05-07 Amgen Fremont Inc. Mammifères transgèniques obtenus par génie génétique contenant des loci des immunoglobulines humaines qui comprennent plusieurs régions de VH et de Vkappa, et anticorps aussi obtenus
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Also Published As

Publication number Publication date
EP3167902B1 (fr) 2020-07-29
CY2014046I1 (el) 2016-04-13
CY1118429T1 (el) 2017-06-28
FR14C0080I2 (fr) 2015-10-30
MXPA02010059A (es) 2004-08-19
WO2001078779A2 (fr) 2001-10-25
US20010046496A1 (en) 2001-11-29
JP5764524B2 (ja) 2015-08-19
NL300702I2 (fr) 2016-01-28
HK1054320A1 (en) 2003-11-28
ES2398096T3 (es) 2013-03-13
JP2012184241A (ja) 2012-09-27
LUC00014I1 (fr) 2017-04-18
AU2001251629A1 (en) 2001-10-30
EP3167902A1 (fr) 2017-05-17
US20200002423A1 (en) 2020-01-02
CY2014046I2 (el) 2016-04-13
FR14C0080I1 (fr) 2014-12-19
US20120034243A1 (en) 2012-02-09
BE2017C009I2 (fr) 2017-09-22
JP6021959B2 (ja) 2016-11-09
DK2298348T3 (en) 2017-01-30
DK1278543T3 (da) 2013-01-14
JP2015083603A (ja) 2015-04-30
CA2406220C (fr) 2019-02-12
WO2001078779A3 (fr) 2002-07-04
JP2003531129A (ja) 2003-10-21
EP1278543B1 (fr) 2012-09-19
CA2406220A1 (fr) 2001-10-25
PT2298348T (pt) 2017-01-04
US20050095238A1 (en) 2005-05-05
EP2298348A1 (fr) 2011-03-23
NL300702I1 (fr) 2016-01-28
EP2298348B1 (fr) 2016-10-12
EP1278543A2 (fr) 2003-01-29
EP2298348B9 (fr) 2017-02-15
ES2609689T3 (es) 2017-04-21
CY1113489T1 (el) 2016-04-13
US20140186345A1 (en) 2014-07-03

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