KR920703501A - 세바스산 및 그 유도체의 장 경우 영양 및 비경구적 영양에서의 용도 및 이들 화합물을 함유한 의약 조성물 - Google Patents
세바스산 및 그 유도체의 장 경우 영양 및 비경구적 영양에서의 용도 및 이들 화합물을 함유한 의약 조성물Info
- Publication number
- KR920703501A KR920703501A KR1019920700133A KR920700133A KR920703501A KR 920703501 A KR920703501 A KR 920703501A KR 1019920700133 A KR1019920700133 A KR 1019920700133A KR 920700133 A KR920700133 A KR 920700133A KR 920703501 A KR920703501 A KR 920703501A
- Authority
- KR
- South Korea
- Prior art keywords
- sebacic acid
- triglyceride
- composition
- pharmacologically acceptable
- salts
- Prior art date
Links
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 title claims description 25
- 235000016236 parenteral nutrition Nutrition 0.000 title claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 4
- 230000000968 intestinal effect Effects 0.000 title claims description 3
- 150000001875 compounds Chemical class 0.000 title description 2
- 235000016709 nutrition Nutrition 0.000 title description 2
- 150000003839 salts Chemical class 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 5
- -1 sebacic acid triglycerides Chemical class 0.000 claims 4
- 150000003626 triacylglycerols Chemical class 0.000 claims 3
- 159000000001 potassium salts Chemical class 0.000 claims 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 150000003330 sebacic acids Chemical class 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/20—Sebacic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
내용 없음
Description
세바스산 및 그 유도체의 장 경우 영양 및 비경구적 영양에서의 용도 및 이들 화합물을 함유한 의약 조성물
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 세바스산 및 약리학적으로 허용되는 그 유도체의 장 경유 영양 및 비경구적 영양용의 의약 조성물 제조를 유한 용도.
- 제1항에 있어서 세바스산의 유도체는 세바스산의 약리학적으로 허용되는 염, 세바스산 트리글리세리드 및 세바스산 트리글리세리드의 약리학적으로 허용되는 염으로 된 군으로부터 선택되는 것인 용도.
- 제2항에 있어서 세바스산 또는 세바스산 트리글리세리드의 약리학적으로 허용되는 염은 나트륨 염 및 칼륨 염으로 부더 선택되는 것인 용도.
- 영양적으로 활성기질로서 세바스산 트리글리세리드 및 약리학적으로 허용되는 그 염을 함유하는 장 경유 영양 또는 비경구적 영양용의 의약 조성물.
- 제4항에 있어서 세바스산의 약리학적로 허용되는 염은 나트륨 및 칼륨 염으로부터 선택되는 것인 조성물.
- 제4항에 있어서 세바스산 트리글리세리드 또는 세바스산 트리글리세리드의 약제학적으로 허용되는 염을 0.2∼1몰/ℓ함유하는 수용액 상태의 조성물.
- 제6항에 있어서 세바스산의 트리글리세리드 또는 트리글리세리드 염을 약 0.5몰/ℓ 함유하는 조성물.
- 제4항에 있어서 세바스산의 트리글리세리드 또는 트리글리세리드 염을 0.5∼1.5g 함유하는 단위제형 형태의 경구 투여용 조성물.
- 제8항에 있어서 캡슐형태의 조성물.
- 세바스산 트리글리세리드의 알칼리 금속염.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48255A/89 | 1989-07-31 | ||
| IT8948255A IT1232161B (it) | 1989-07-31 | 1989-07-31 | Uso dell'acido sebacico e di suoi derivati nell'alimentazione enterale e parentaerale e composizioni farmaceutiche contenenti tali composti |
| PCT/IT1990/000073 WO1991001963A2 (en) | 1989-07-31 | 1990-07-30 | Use of sebacic acid and derivatives thereof in enteral and parenteral nutrition and pharmaceutical compositions containing said compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR920703501A true KR920703501A (ko) | 1992-12-18 |
| KR0165899B1 KR0165899B1 (ko) | 1999-03-20 |
Family
ID=11265518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920700133A KR0165899B1 (ko) | 1989-07-31 | 1990-07-30 | 세바스산 및 그 유도체의 장 경유 및 비경구적 영양에서의 용도 및 이들 화합물을 함유한 의약 조성물 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5272177A (ko) |
| EP (1) | EP0484372B1 (ko) |
| JP (1) | JP2672398B2 (ko) |
| KR (1) | KR0165899B1 (ko) |
| AT (1) | ATE106379T1 (ko) |
| CA (1) | CA2062976C (ko) |
| DE (1) | DE69009481T2 (ko) |
| DK (1) | DK0484372T3 (ko) |
| ES (1) | ES2054364T3 (ko) |
| GR (1) | GR1001089B (ko) |
| HK (1) | HK1006451A1 (ko) |
| IE (1) | IE62466B1 (ko) |
| IT (1) | IT1232161B (ko) |
| WO (1) | WO1991001963A2 (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080070981A1 (en) * | 2000-02-23 | 2008-03-20 | Henryk Borowy-Borowski | Water-soluble compositions of bioactive lipophilic compounds |
| CN1324000C (zh) * | 2005-03-25 | 2007-07-04 | 通辽市康斯特油化有限责任公司 | 癸二酸双钾（钠）盐制造工艺 |
| EP2085082A1 (en) * | 2008-01-29 | 2009-08-05 | Nutromnia S.R.L. | Treatment of cognitive decline |
| ES2390620T3 (es) * | 2008-03-10 | 2012-11-14 | Nestec S.A. | Ácidos dicarboxílicos de cadena mediana y sus derivados y trastornos metabólicos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386104A (en) * | 1977-04-19 | 1983-05-31 | Nazzaro Porro Marcella | Process for the treatment of acne |
| US4528197A (en) * | 1983-01-26 | 1985-07-09 | Kabivitrum Ab | Controlled triglyceride nutrition for hypercatabolic mammals |
| JPS61171417A (ja) * | 1985-01-23 | 1986-08-02 | Wakunaga Seiyaku Kk | 抗糖尿病剤 |
| IL84599A0 (en) * | 1986-12-09 | 1988-04-29 | Byk Gulden Lomberg Chem Fab | Pharmaceutical composition containing urapidil and process for the preparation thereof |
| US4885282A (en) * | 1987-07-02 | 1989-12-05 | Thornfeldt Carl R | Treatment of hyperhidrosis, ichthyosis and wrinkling |
| US4906455A (en) * | 1988-04-15 | 1990-03-06 | Wm. Wrigley Jr. Company | Method for treating xerostomia employing chewing gum containing relatively insoluble, hydrophobic, food-grade organic acid |
-
1989
- 1989-07-31 IT IT8948255A patent/IT1232161B/it active
-
1990
- 1990-07-27 GR GR900100576A patent/GR1001089B/el not_active IP Right Cessation
- 1990-07-30 AT AT90910871T patent/ATE106379T1/de not_active IP Right Cessation
- 1990-07-30 ES ES90910871T patent/ES2054364T3/es not_active Expired - Lifetime
- 1990-07-30 EP EP90910871A patent/EP0484372B1/en not_active Expired - Lifetime
- 1990-07-30 IE IE276190A patent/IE62466B1/en not_active IP Right Cessation
- 1990-07-30 WO PCT/IT1990/000073 patent/WO1991001963A2/en active IP Right Grant
- 1990-07-30 DE DE69009481T patent/DE69009481T2/de not_active Expired - Fee Related
- 1990-07-30 JP JP2510701A patent/JP2672398B2/ja not_active Expired - Fee Related
- 1990-07-30 CA CA002062976A patent/CA2062976C/en not_active Expired - Fee Related
- 1990-07-30 KR KR1019920700133A patent/KR0165899B1/ko not_active IP Right Cessation
- 1990-07-30 DK DK90910871.4T patent/DK0484372T3/da active
- 1990-09-14 US US07/820,875 patent/US5272177A/en not_active Expired - Lifetime
-
1998
- 1998-06-18 HK HK98105616A patent/HK1006451A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991001963A2 (en) | 1991-02-21 |
| US5272177A (en) | 1993-12-21 |
| IE902761A1 (en) | 1991-02-27 |
| CA2062976C (en) | 2000-03-21 |
| IT1232161B (it) | 1992-01-25 |
| DK0484372T3 (da) | 1994-08-15 |
| IT8948255A0 (it) | 1989-07-31 |
| GR1001089B (el) | 1993-04-28 |
| GR900100576A (en) | 1991-12-10 |
| IE62466B1 (en) | 1995-02-08 |
| KR0165899B1 (ko) | 1999-03-20 |
| EP0484372B1 (en) | 1994-06-01 |
| CA2062976A1 (en) | 1991-02-01 |
| HK1006451A1 (en) | 1999-02-26 |
| ES2054364T3 (es) | 1994-08-01 |
| EP0484372A1 (en) | 1992-05-13 |
| JP2672398B2 (ja) | 1997-11-05 |
| WO1991001963A3 (en) | 1991-06-27 |
| ATE106379T1 (de) | 1994-06-15 |
| JPH04507407A (ja) | 1992-12-24 |
| DE69009481D1 (de) | 1994-07-07 |
| DE69009481T2 (de) | 1994-10-20 |
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| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E902 | Notification of reason for refusal | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 20060918 Year of fee payment: 9 |
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| LAPS | Lapse due to unpaid annual fee |