KR890004705A - 항바이러스성 제제 - Google Patents

항바이러스성 제제 Download PDF

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Publication number
KR890004705A
KR890004705A KR1019880011892A KR880011892A KR890004705A KR 890004705 A KR890004705 A KR 890004705A KR 1019880011892 A KR1019880011892 A KR 1019880011892A KR 880011892 A KR880011892 A KR 880011892A KR 890004705 A KR890004705 A KR 890004705A
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KR
South Korea
Prior art keywords
dideoxycytidine
dideoxynucleoside
patient
day
composition
Prior art date
Application number
KR1019880011892A
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English (en)
Other versions
KR960014991B1 (ko
Inventor
수 화이젠
Original Assignee
장-자끄 오가이, 프리돌린 클라우스너
에프·호프만-라 로슈 앤드 캄파니 아크 티엔게젤샤프트
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Application filed by 장-자끄 오가이, 프리돌린 클라우스너, 에프·호프만-라 로슈 앤드 캄파니 아크 티엔게젤샤프트 filed Critical 장-자끄 오가이, 프리돌린 클라우스너
Publication of KR890004705A publication Critical patent/KR890004705A/ko
Application granted granted Critical
Publication of KR960014991B1 publication Critical patent/KR960014991B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

항바이러스성 제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 0.001 내지 0.10mg/kg/일의 디데옥시뉴클레오시드 동족체를 환자에게 투여하기에 충분한 양으로 용량 단위내에 디데옥시뉴클레오시드 동족체를 함유하는, 환자에게 AIDS를 예방하거나 AIDS 레트로 바이러스로 감염된 환자를 치료하기에 적합한 약제학적 조성물.
  2. 제1항에 있어서, 디데옥시뉴클레오시드 동족체가 2',3'-디데옥시시티딘인 조성물.
  3. 제2항에 있어서, 1회 용량단위로서 2',3'-디데옥시시티딘 0.01 내지 5mg을 함유하는 조성물.
  4. 제2항에 있어서, 경구 또는 정맥내 투여용 조성물.
  5. 특히 실시예를 참조로 하는 전술한 바와 같은 본 발명.
  6. 환자에게 0.001 내지 0.10mg/kg/일의 디데옥시뉴클레오시드 동족체를 투여함을 특징으로 하여, 환자에게 AIDS를 예방하거나 AIDS 레트로 바이러스로 감염된 환자를 치료하는 방법.
  7. 제6항에 있어서, 디데옥시뉴클레오시드 동족체가 2',3'-디데옥시시티딘인 방법.
  8. 제6항에 있어서, 0.001 내지 0.05mg/kg/일의 2',3'-디데옥시시티딘을 1일 1 내지 6회 용량으로 투여하는 방법.
  9. 제8항에 있어서, 2',3'-디데옥시시티딘을 경구 또는 정맥내로 투여하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880011892A 1987-09-18 1988-09-15 2',3'-디데옥시시티딘을 극히 저용량으로 함유하는 약제학적 조성물 KR960014991B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9825587A 1987-09-18 1987-09-18
US098,255 1987-09-18
US07/098,255 1987-09-18

Publications (2)

Publication Number Publication Date
KR890004705A true KR890004705A (ko) 1989-05-09
KR960014991B1 KR960014991B1 (ko) 1996-10-23

Family

ID=22268410

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880011892A KR960014991B1 (ko) 1987-09-18 1988-09-15 2',3'-디데옥시시티딘을 극히 저용량으로 함유하는 약제학적 조성물

Country Status (13)

Country Link
EP (1) EP0307914B1 (ko)
JP (1) JP2648329B2 (ko)
KR (1) KR960014991B1 (ko)
AT (1) ATE78693T1 (ko)
AU (1) AU616427B2 (ko)
CA (1) CA1334166C (ko)
DE (1) DE3873232T2 (ko)
HK (1) HK99593A (ko)
HU (1) HUT47856A (ko)
IE (1) IE62191B1 (ko)
IL (1) IL87776A (ko)
PH (1) PH24796A (ko)
ZA (1) ZA886107B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US5276019A (en) * 1987-03-25 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
EP0355245A1 (fr) * 1988-08-26 1990-02-28 Michel Vandevelde Utilisation d'agents d'inhibition de la réverse-transcriptase des rétrovirus
JPH04501857A (ja) * 1989-05-15 1992-04-02 アメリカ合衆国 肝炎の治療方法
EP0472595A4 (en) * 1989-05-15 1992-07-08 Us Commerce Method of treatment of hepatitis
US5585367A (en) * 1990-04-19 1996-12-17 Previsan S.A. Method of treating humans and animals infected with viruses of the retrovirus group
ES2060373T3 (es) * 1990-04-19 1994-11-16 Previsan Sa Derivados azoicos, compuestos farmaceuticos y desinfectantes que los contienen y su utilizacion contra el sida.
JP2593409Y2 (ja) * 1992-12-02 1999-04-12 エスエムケイ株式会社 キーボードスイッチ
DE4419256A1 (de) * 1994-06-01 1995-12-07 Rau Freiherr Von Nagell Helmut Verwendung von intravenös applizierbarem Eisen zur Therapie von Tumorerkrankungen und/oder Infektionskrankheiten
DE4421159C1 (de) * 1994-06-20 1995-08-24 Thomas Bruns Verwendung von Eisen(III)-oxid (Fe¶2¶O¶3¶) bei Immunschwäche

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206497B1 (en) * 1985-05-15 1994-07-20 The Wellcome Foundation Limited Therapeutic nucleosides and their preparation
GB8512542D0 (en) * 1985-05-17 1985-06-19 Atomic Energy Authority Uk Improved cutting edges
JPS62501777A (ja) * 1985-08-26 1987-07-16 アメリカ合衆国 ２′，３′―ジデオキシシチジンを含有する抗ｈｔｌｖ―３／ｌａｖ剤
JPS62501712A (ja) * 1985-08-26 1987-07-09 アメリカ合衆国 ２′、３′―ジデオキシイノシン、２′，３′―ジデオキシグアノシンまたは２′，３′―ジデオキシアデノシンを含有する抗ｈｔｌｖ―３／ｌａｖ剤

Also Published As

Publication number Publication date
ATE78693T1 (de) 1992-08-15
PH24796A (en) 1990-10-30
IE882836L (en) 1989-03-18
ZA886107B (en) 1989-04-26
AU616427B2 (en) 1991-10-31
EP0307914A3 (en) 1989-08-09
IL87776A (en) 1994-01-25
AU2234588A (en) 1989-03-23
DE3873232T2 (de) 1992-12-03
HUT47856A (en) 1989-04-28
IE62191B1 (en) 1994-12-28
JP2648329B2 (ja) 1997-08-27
KR960014991B1 (ko) 1996-10-23
JPS6483020A (en) 1989-03-28
HK99593A (en) 1993-09-30
CA1334166C (en) 1995-01-31
EP0307914B1 (en) 1992-07-29
EP0307914A2 (en) 1989-03-22
DE3873232D1 (de) 1992-09-03

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