KR890001525A - 지효성 경피 제제 - Google Patents

지효성 경피 제제 Download PDF

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Publication number
KR890001525A
KR890001525A KR1019880009259A KR880009259A KR890001525A KR 890001525 A KR890001525 A KR 890001525A KR 1019880009259 A KR1019880009259 A KR 1019880009259A KR 880009259 A KR880009259 A KR 880009259A KR 890001525 A KR890001525 A KR 890001525A
Authority
KR
South Korea
Prior art keywords
sustained
adhesive
release transdermal
transdermal formulation
skin
Prior art date
Application number
KR1019880009259A
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English (en)
Inventor
요시오 우에다
소뚜 아사꾸라
요시오 무라가미
또시오미 나가떼
Original Assignee
후지사와 도모기찌로
후지사와 야꾸힝 고오교오 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 후지사와 도모기찌로, 후지사와 야꾸힝 고오교오 가부시기가이샤 filed Critical 후지사와 도모기찌로
Publication of KR890001525A publication Critical patent/KR890001525A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

지효성 경피 제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 최소한 2개의 접착제 층을 갖으며, 이 접착제 층중 적용시 피부에서 가장 멀리 떨어진 층 이외의 다른 한 층에 고체 분말을 분산된 상태로 포함하며, 적용시 피부에서 가장 멀리 떨어진 층내에 약제를 포함하는 것을 특징으로 하는 지효성 경피 제제.
  2. 제1항에 있어서, 두 층의 접착제 층을 갖으며, 이때 고체 분말은 적용시 피부에 가까운 접착제 층내에 분산 상태로 포함되며 약제는 다른 접착제 층중에 포함되는 것을 특징으로 하는 지효성 경피 제제.
  3. 제1항 또는 제2항에 있어서, 고체 분말이 탈크 또는 메타크릴산 수지인 지효성 경피 제제.
  4. 제1항 내지 제3항 중 어느 한 항에 있어서, 접착제가 아크릴산 에스테르 접착제 및/또는 실리콘 접착제인 지효성 경피 제제.
  5. 제1항 내지 제4항 중 어느 한 항에 있어서, 약제가 2-니트록시 메틸-6-클로로피리딘인 지효성 경피 제제
  6. 제1항 내지 제4항 중 어느 한 항에 있어서, 약제가 β-시클로 멕스트린을 갖는 2-니트록시 메틸-6-클로로피리딘인 내포화합물인 지효성 경피 제제
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880009259A 1987-07-06 1988-07-23 지효성 경피 제제 KR890001525A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18579087 1987-07-24
JP62-185790 1987-07-24

Publications (1)

Publication Number Publication Date
KR890001525A true KR890001525A (ko) 1989-03-27

Family

ID=16176941

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880009259A KR890001525A (ko) 1987-07-06 1988-07-23 지효성 경피 제제

Country Status (9)

Country Link
US (1) US4889721A (ko)
EP (1) EP0301424B1 (ko)
JP (1) JP2638956B2 (ko)
KR (1) KR890001525A (ko)
AT (1) ATE88906T1 (ko)
AU (1) AU606973B2 (ko)
DE (1) DE3880754T2 (ko)
ES (1) ES2054744T3 (ko)
ZA (1) ZA885069B (ko)

Families Citing this family (14)

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WO1990015568A2 (en) * 1989-06-02 1990-12-27 Stanley Theodore H Apparatus and methods for noninvasive blood glucose monitoring
US5139023A (en) * 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
ES2196208T3 (es) * 1996-03-09 2003-12-16 Nitto Denko Corp Preparacion percutanea adhesiva.
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
GB0309631D0 (en) * 2003-04-28 2003-06-04 Bayer Cropscience Ag Novel process for the preparation of 2-aminomethylpyridine derivatives
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US20050202073A1 (en) 2004-03-09 2005-09-15 Mylan Technologies, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
JP4557596B2 (ja) * 2004-04-28 2010-10-06 積水化成品工業株式会社 外用貼付剤およびその製造方法、並びにその使用方法
WO2006091795A2 (en) * 2005-02-25 2006-08-31 Board Of Regents, The University Of Texas System METHODS AND COMPOSITIONS INVOLVING EXPRESSION OF α1C SUBUNIT OF L-TYPE CALCIUM CHANNELS IN SMOOTH MUSCLE CELLS
WO2007099966A1 (ja) * 2006-02-28 2007-09-07 Hisamitsu Pharmaceutical Co., Inc. 経皮吸収型製剤
KR101239150B1 (ko) * 2012-02-28 2013-03-06 에스케이케미칼주식회사 도네페질-함유 경피흡수제제 및 그의 제조방법
WO2016020901A1 (en) 2014-08-07 2016-02-11 Acerta Pharma B.V. Methods of treating cancers, immune and autoimmune diseases, and inflammatory diseases based on btk occupancy and btk resynthesis rate

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US3742951A (en) * 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
JPS5530216B2 (ko) * 1974-02-08 1980-08-09
JPS57120518A (en) * 1981-01-19 1982-07-27 Tanabe Seiyaku Co Ltd Preparation of microcapsule
JPS57130914A (en) * 1981-02-04 1982-08-13 Agency Of Ind Science & Technol Prolongation of activity retention
JPS5910513A (ja) * 1982-07-12 1984-01-20 Nitto Electric Ind Co Ltd 医薬製剤
JPS5920374A (ja) * 1982-07-24 1984-02-02 Dia Seiyaku Kk 貼付剤
DK311683A (da) * 1982-07-26 1984-01-27 Fujisawa Pharmaceutical Co Fremgangsmaade til fremstilling af pyridylalkylnitratforbindelser
JPS6081166A (ja) * 1983-10-11 1985-05-09 Fujisawa Pharmaceut Co Ltd ２−ニトロオキシメチル−６−クロロピリジンのβ−シクロデキストリン包接化合物およびその製造法
JPS60156607A (ja) * 1984-01-25 1985-08-16 Fujisawa Pharmaceut Co Ltd ２−ニトロオキシメチル−６−クロロピリジンまたはそのβ−シクロデキストリン包接化合物含有経皮吸収製剤
JPS6130517A (ja) * 1984-07-20 1986-02-12 Nichiban Co Ltd 三層構造より成る粘膜用貼付剤
JPS6215A (ja) * 1985-02-26 1987-01-06 Fujisawa Pharmaceut Co Ltd ２−ニトロオキシメチル−６−クロロピリジンまたはそのβ−シクロデキストリン包接化合物含有持続性製剤
EP0241806A1 (en) * 1986-04-14 1987-10-21 Fujisawa Pharmaceutical Co., Ltd. Sustained-release transdermal delivery preparations
JP2969313B2 (ja) * 1992-10-15 1999-11-02 富士写真フイルム株式会社 放射線画像読取処理条件決定方法

Also Published As

Publication number Publication date
DE3880754T2 (de) 1993-10-07
DE3880754D1 (de) 1993-06-09
ZA885069B (en) 1989-03-29
EP0301424A2 (en) 1989-02-01
AU1970888A (en) 1989-01-27
US4889721A (en) 1989-12-26
JPH01104008A (ja) 1989-04-21
ES2054744T3 (es) 1994-08-16
EP0301424A3 (en) 1989-07-12
ATE88906T1 (de) 1993-05-15
EP0301424B1 (en) 1993-05-05
JP2638956B2 (ja) 1997-08-06
AU606973B2 (en) 1991-02-21

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