KR860006986A - 수화 부착식 겔의 제조방법 - Google Patents

수화 부착식 겔의 제조방법 Download PDF

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KR860006986A
KR860006986A KR1019860001655A KR860001655A KR860006986A KR 860006986 A KR860006986 A KR 860006986A KR 1019860001655 A KR1019860001655 A KR 1019860001655A KR 860001655 A KR860001655 A KR 860001655A KR 860006986 A KR860006986 A KR 860006986A
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compound
residue
group
adhesive gel
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KR1019860001655A
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KR900004316B1 (ko
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히로시 도이
히로시 도이 (외 1)
마사노리 이노우에
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니혼유시 가부시끼가이샤
오가와 데루시
니혼 유시 가부시끼 가이샤
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Priority claimed from JP60045765A external-priority patent/JPS61205209A/ja
Priority claimed from JP60124740A external-priority patent/JPS61282314A/ja
Application filed by 니혼유시 가부시끼가이샤, 오가와 데루시, 니혼 유시 가부시끼 가이샤 filed Critical 니혼유시 가부시끼가이샤
Publication of KR860006986A publication Critical patent/KR860006986A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins

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  • Life Sciences & Earth Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)

Abstract

내용 없음

Description

수화 부착식 겔의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 실시에 1~7 및 비교예 1 및 2에서의 시간에 따른 부착력의 변화를 나타낸다. 제2도는 실시예 1~7 및 비교예 1 및 2에서의 재부착 시험에 따른 재부착력의 변화를 나타낸다. 제3도는 실시에 8~10 및 비교예 3 및 4에서의 시간에 따른 부착력의 변화를 나타낸다.

Claims (5)

  1. 아미노기를 측쇄에 갖는 단백질을 필수적으로 함유하는 수용액을 하기 일반식(1)의 N-히드록시이미도에 스테르 화합물과 반응시킴을 특징으로 하는 수화 부착식겔의 제조방법.
    식중, X는 2~6개의 탄소원자 및 2~6개의 히드록시기를 갖는 화합물의 잔기이고; A는 옥시에틸렌, 옥시프로필렌 및 옥시부틸렌기들로부터 선택된 1 또는 그 이상의 기이며; Y는 이염기성산의 잔기이고; Z는
    m은 1~3000이고; 및 n은 2~6이다.
  2. 제1항에 있어서, 겔화제지제가염소, 브롬, 질산기를 함유하는 무기화합물 및 유기기, 레조르시놀, 히드로퀴논, 피로카테콜, 피로갈롤, 알코올, 우레아 및 푸르푸랄로 구성된 군으로부터 선택된 화합물임을 특징으로 하는 수화 부착식 겔의 제조방법.
  3. 제1항에 있어서, 친수성 점착제가 상온에서 액체 상태인 글리세롤, 에틸렌글리콜, 프로필렌글리콜, 폴리에틸렌글리콜 및 폴리프로필렌글리콜로 구성된 군으로부터 선택됨을 특징으로 하는 수화 부착식 겔의 제조방법.
  4. 제1항에 있어서, 수화 부착식겔이 연고 및 경고로 구성된 군으로부터 선택됨을 특징으로 하는 수화 부착식 겔의 제조방법.
  5. 아미노기를 측쇄에 갖는 단백질, 겔화제지제 및 친수성 점착제를 필수적으로 함유하는 수용액을 하기 일반식(1)의 N-히드록시이미도에스테르 화합물과 반응시킴을 특징으로 하는 수화부착식겔의 제조방법.
    식중, X는 2~6개의 탄소원자 및 2~6개의 히드록시기를 갖는 화합물의 잔기이고; A는 옥시에틸렌, 옥시프로필렌 및 옥시부틸렌기들로부터 선택된 또는 1 그 이상의 기이며; Y는 이염기성산의 잔기이고; Z는
    m은 1~3000이고; 및 n은 2~6이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860001655A 1985-03-09 1986-03-08 수화부착식 겔의 제조방법 KR900004316B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP45765 1985-03-09
JP60045765A JPS61205209A (ja) 1985-03-09 1985-03-09 パツプ剤用膏体
JP45,765 1985-03-09
JP124,740 1985-06-08
JP124740 1985-06-08
JP60124740A JPS61282314A (ja) 1985-06-08 1985-06-08 パツプ剤用膏体

Publications (2)

Publication Number Publication Date
KR860006986A true KR860006986A (ko) 1986-10-06
KR900004316B1 KR900004316B1 (ko) 1990-06-22

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KR1019860001655A KR900004316B1 (ko) 1985-03-09 1986-03-08 수화부착식 겔의 제조방법

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US (1) US4839345A (ko)
EP (1) EP0194807B1 (ko)
KR (1) KR900004316B1 (ko)
CN (1) CN1022022C (ko)
AU (1) AU576946B2 (ko)
CA (1) CA1262092A (ko)
DE (1) DE3674815D1 (ko)

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AU5429186A (en) 1986-09-11
CA1262092A (en) 1989-10-03
DE3674815D1 (de) 1990-11-15
EP0194807A2 (en) 1986-09-17
US4839345A (en) 1989-06-13
AU576946B2 (en) 1988-09-08
KR900004316B1 (ko) 1990-06-22
EP0194807B1 (en) 1990-10-10
EP0194807A3 (en) 1987-09-02
CN1022022C (zh) 1993-09-08
CN86102388A (zh) 1986-09-17

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