KR20210104887A - 라만 분광법을 사용하여 바이러스 역가를 측정하는 방법 - Google Patents

라만 분광법을 사용하여 바이러스 역가를 측정하는 방법 Download PDF

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KR20210104887A
KR20210104887A KR1020217023614A KR20217023614A KR20210104887A KR 20210104887 A KR20210104887 A KR 20210104887A KR 1020217023614 A KR1020217023614 A KR 1020217023614A KR 20217023614 A KR20217023614 A KR 20217023614A KR 20210104887 A KR20210104887 A KR 20210104887A
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sample
wavenumber
wavenumber ranges
vip
measured
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존 처치웰
마크 올리비에 바라데즈
데이미언 마셜
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셀 테라피 캐터펄트 리미티드
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/129Using chemometrical methods
    • G01N2201/1293Using chemometrical methods resolving multicomponent spectra
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/129Using chemometrical methods
    • G01N2201/1296Using chemometrical methods using neural networks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses

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  • Software Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020217023614A 2018-12-24 2019-12-23 라만 분광법을 사용하여 바이러스 역가를 측정하는 방법 KR20210104887A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1821206.8A GB2580186B (en) 2018-12-24 2018-12-24 Monitoring viral titre using Raman Spectroscopy
GB1821206.8 2018-12-24
PCT/GB2019/053695 WO2020136376A1 (en) 2018-12-24 2019-12-23 Methods for determining viral titre using raman spectroscopy

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KR20210104887A true KR20210104887A (ko) 2021-08-25

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KR1020217023614A KR20210104887A (ko) 2018-12-24 2019-12-23 라만 분광법을 사용하여 바이러스 역가를 측정하는 방법

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US (2) US11703455B2 (zh)
EP (1) EP3903096A1 (zh)
JP (1) JP2022515417A (zh)
KR (1) KR20210104887A (zh)
CN (1) CN113490843A (zh)
AU (1) AU2019412791A1 (zh)
CA (1) CA3123168A1 (zh)
GB (1) GB2580186B (zh)
IL (1) IL284283B1 (zh)
WO (1) WO2020136376A1 (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110609030B (zh) * 2019-10-22 2022-02-25 上海海关动植物与食品检验检疫技术中心 一种基于检出概率模型的拉曼快检性能综合评价方法
GB202010104D0 (en) * 2020-07-01 2020-08-12 Cell Therapy Catapult Ltd Method
US20230160829A1 (en) * 2021-11-19 2023-05-25 Janssen Biotech, Inc. Methods for determination of virus titer in a sample using raman spectroscopy
WO2023227438A1 (en) 2022-05-23 2023-11-30 F. Hoffmann-La Roche Ag Raman-based method for the differentiation of aav particle serotype and aav particle loading status

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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CN1242937A (zh) * 1998-07-28 2000-02-02 中国科学院生物物理研究所 多环醌类化合物的光敏作用杀灭血制品中艾滋病毒的方法
US20070134733A1 (en) * 2003-07-10 2007-06-14 Parallax Biosystems, Inc. Raman signature probes and their use in the detection and imaging of molecular processes and structures
US20080113337A1 (en) * 2004-11-12 2008-05-15 The New Industry Research Organization Method of Examining/Judging Presence of Virus Infection such as HIV or Presence of Prion Infection by Near-Infrared Spectroscopy and Device Used in Same
JP2005140794A (ja) * 2005-01-13 2005-06-02 E Graw An 化学物質および微生物の検出のためのラマンオプトロードプロセスおよび装置
US7889334B2 (en) * 2005-03-15 2011-02-15 University Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of bacteria and methods of use thereof
US7940387B2 (en) * 2005-03-15 2011-05-10 Univeristy Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of viruses and methods of use thereof
US20100279886A1 (en) * 2007-04-03 2010-11-04 University Of Rochester Two-dimensional photonic bandgap structures for ultrahigh-sensitivity biosensing
DE102008047240B4 (de) * 2008-09-11 2016-03-31 Friedrich-Schiller-Universität Jena Verfahren zur Identifikation von Einzelviren in einer Probe
US9662047B2 (en) * 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
TWI487910B (zh) * 2010-09-07 2015-06-11 國立成功大學 倒多角錐陣列型免標定病毒檢測基板、系統及方法
US20120316446A1 (en) * 2011-06-07 2012-12-13 Sinisa Vukelic Raman spectral analysis for disease detection and monitoring
KR101523337B1 (ko) 2012-09-20 2015-05-28 주식회사 바이오센 라만 분광법 및 케모메트릭스를 이용한 식물의 바이러스 감염에 대한 분석방법
EP3922965A3 (en) * 2013-08-07 2022-03-30 Wayne State University Hand-held micro-raman based detection instrument and method of detection
JP6375509B2 (ja) * 2013-12-17 2018-08-22 パナソニックIpマネジメント株式会社 報知装置、空気清浄機、および、報知方法
CN105630743B (zh) * 2015-12-24 2018-05-01 浙江大学 一种光谱波数的选择方法
CN105603125B (zh) * 2016-03-09 2019-07-12 华南农业大学 一种快速检测禽病病毒的检测试剂盒及其检测方法
CN108088834B (zh) * 2017-09-13 2020-04-28 新疆大学 基于优化反向传播神经网络的包虫病血清拉曼光谱诊断仪
CN107937957B (zh) * 2017-11-23 2020-05-26 华中农业大学 表面增强拉曼基底的制备方法及该基底用于检测动物病毒

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Publication number Publication date
WO2020136376A1 (en) 2020-07-02
IL284283B1 (en) 2024-03-01
CA3123168A1 (en) 2020-07-02
CN113490843A (zh) 2021-10-08
AU2019412791A1 (en) 2021-07-08
US20230384228A1 (en) 2023-11-30
US11703455B2 (en) 2023-07-18
GB201821206D0 (en) 2019-02-06
GB2580186B (en) 2021-09-15
EP3903096A1 (en) 2021-11-03
GB2580186A (en) 2020-07-15
US20220018782A1 (en) 2022-01-20
IL284283A (en) 2021-08-31
JP2022515417A (ja) 2022-02-18

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