KR20180006902A - 카바지탁셀 지방 에멀젼 주사제 및 이를 제조하는 방법 및 그의 사용 - Google Patents

카바지탁셀 지방 에멀젼 주사제 및 이를 제조하는 방법 및 그의 사용 Download PDF

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Publication number
KR20180006902A
KR20180006902A KR1020177031808A KR20177031808A KR20180006902A KR 20180006902 A KR20180006902 A KR 20180006902A KR 1020177031808 A KR1020177031808 A KR 1020177031808A KR 20177031808 A KR20177031808 A KR 20177031808A KR 20180006902 A KR20180006902 A KR 20180006902A
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KR
South Korea
Prior art keywords
emulsion
injection
lecithin
cabbage
freeze
Prior art date
Application number
KR1020177031808A
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English (en)
Korean (ko)
Inventor
지엔밍 첸
바오'안 가오
친친 쭤우
구오쳉 왕
구오준 양
웬리 리오
Original Assignee
장쑤 태슬리 디이 파마슈티컬 컴퍼니 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 장쑤 태슬리 디이 파마슈티컬 컴퍼니 리미티드 filed Critical 장쑤 태슬리 디이 파마슈티컬 컴퍼니 리미티드
Publication of KR20180006902A publication Critical patent/KR20180006902A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020177031808A 2015-05-06 2016-05-06 카바지탁셀 지방 에멀젼 주사제 및 이를 제조하는 방법 및 그의 사용 KR20180006902A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510227743.7A CN106176599A (zh) 2015-05-06 2015-05-06 一种卡巴他赛脂肪乳注射剂及其制备方法
CN201510227743.7 2015-05-06
PCT/CN2016/081245 WO2016177346A1 (zh) 2015-05-06 2016-05-06 一种卡巴他赛脂肪乳注射剂及其制备方法和用途

Publications (1)

Publication Number Publication Date
KR20180006902A true KR20180006902A (ko) 2018-01-19

Family

ID=57218491

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177031808A KR20180006902A (ko) 2015-05-06 2016-05-06 카바지탁셀 지방 에멀젼 주사제 및 이를 제조하는 방법 및 그의 사용

Country Status (9)

Country Link
US (1) US20180153848A1 (zh)
EP (1) EP3292860B1 (zh)
JP (1) JP2018515484A (zh)
KR (1) KR20180006902A (zh)
CN (2) CN106176599A (zh)
AU (1) AU2016258642B2 (zh)
CA (1) CA2982625A1 (zh)
RU (1) RU2716218C2 (zh)
WO (1) WO2016177346A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105983016B (zh) 2015-03-23 2023-08-11 天士力医药集团股份有限公司 一种含有水飞蓟宾的药物组合
CN108464970B (zh) * 2018-04-25 2020-11-03 广州暨南生物医药研究开发基地有限公司 一种代谢及外排双抑制型的安五脂素纳米乳及其制备方法
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
CA3172489A1 (en) 2020-03-23 2021-09-30 Amit KHANDHAR Nanoemulsion compositions and methods for delivery of nra
CN111888332B (zh) * 2020-06-19 2023-07-25 杭州师范大学 一种卡巴他赛柔性乳剂及其制备方法
CN112190547B (zh) * 2020-09-30 2023-01-03 北京诺康达医药科技股份有限公司 脂质微球组合物及其制备方法
WO2023048759A1 (en) * 2021-09-22 2023-03-30 Hdt Bio Corp. Sars-cov-2 rna vaccine compositions and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101019832A (zh) * 2007-03-19 2007-08-22 沈阳药科大学 多西他赛脂肪乳剂及其冻干剂与制备方法
CN102105134B (zh) * 2008-07-23 2013-08-14 印度血清及疫苗有限公司 稳定的可注射的水包油型多烯紫杉醇纳米乳剂
CN102008434B (zh) * 2009-09-04 2012-05-30 辽宁万嘉医药科技有限公司 复方多烯紫杉醇脂微球注射液及其制备方法
US20120065255A1 (en) * 2009-10-19 2012-03-15 Nagesh Palepu Cabazitaxel formulations and methods of preparing thereof
WO2012094020A1 (en) * 2010-01-07 2012-07-12 Innopharma, Inc. Methods and compositions for delivery of taxanes in stable oil-in-water emulsions
CN102970990A (zh) * 2010-05-03 2013-03-13 帝国制药美国公司 非水性紫杉烷前-乳剂制剂以及制备和使用该制剂的方法
TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
CN103006558A (zh) * 2011-12-21 2013-04-03 苏州雷纳药物研发有限公司 一种Cabazitaxel脂质微球注射液及其制备方法
CN104306333B (zh) * 2014-09-28 2017-08-04 沈阳药科大学 一种卡巴他赛脂质微球注射液及其制备方法

Also Published As

Publication number Publication date
EP3292860A4 (en) 2018-03-14
WO2016177346A1 (zh) 2016-11-10
RU2017138067A3 (zh) 2019-05-06
RU2716218C2 (ru) 2020-03-10
CN107530281A (zh) 2018-01-02
CA2982625A1 (en) 2016-11-10
AU2016258642B2 (en) 2020-06-18
RU2017138067A (ru) 2019-05-06
AU2016258642A1 (en) 2017-09-07
JP2018515484A (ja) 2018-06-14
US20180153848A1 (en) 2018-06-07
EP3292860B1 (en) 2019-04-17
CN106176599A (zh) 2016-12-07
EP3292860A1 (en) 2018-03-14

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