KR20090056385A - 지구자를 포함하는 가미 쌍화탕을 유효성분으로 함유하는숙취해소용 조성물 - Google Patents
지구자를 포함하는 가미 쌍화탕을 유효성분으로 함유하는숙취해소용 조성물 Download PDFInfo
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- KR20090056385A KR20090056385A KR1020070123513A KR20070123513A KR20090056385A KR 20090056385 A KR20090056385 A KR 20090056385A KR 1020070123513 A KR1020070123513 A KR 1020070123513A KR 20070123513 A KR20070123513 A KR 20070123513A KR 20090056385 A KR20090056385 A KR 20090056385A
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- lactobacillus
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- ssanghwatang
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-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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Abstract
Description
유산균 균주번호 | 종 |
KFRI 128 | Lactobacillus acidophilus |
164 | Lactobacillus fermentum |
345 | Lactobacillus bulgaricus |
442 | Lactobacillus delbrueckii subsp . lactis |
658 | Lactobacillus gasseri |
692 | Lactobacillus casei |
693 | Lactobacillus casei |
KCTC 5033 | Lactobacillus rhamnosus |
군 | 성 | 동물 번호 | 에탄올(㎖/㎏) | AD 부피a) (㎖/㎏) | 복용량 (㎖/㎏) |
CON | 수컷 | 1 ~ 6 | 0 | 10 | 0 |
NCT | 수컷 | 7 ~ 12 | 10 | 10 | 0 |
SHT | 수컷 | 13 ~ 18 | 10 | 10 | 15 |
HST | 수컷 | 19 ~ 24 | 10 | 10 | 15 |
GMT | 수컷 | 25 ~ 30 | 10 | 10 | 15 |
CDT | 수컷 | 31 ~ 36 | 10 | 10 | 15 |
YMT | 수컷 | 37 ~ 42 | 10 | 10 | 15 |
SMT | 수컷 | 43 ~ 48 | 10 | 10 | 15 |
S164 | 수컷 | 49 ~ 54 | 10 | 10 | 15 |
성 | 수컷 | |||||
군 | CON | NCT | SHT | HST | GMT | CDT |
60% 에탄올(㎎/㎗) | 10 | 10 | 10 | 10 | 10 | 10 |
복용량(㎖/㎏) | 0 | 0 | 15 | 15 | 15 | 15 |
동물 수 | 6 | 6 | 6 | 6 | 6 | 6 |
120 분 | 28.0 (0.0) | 267.8 (95.3) | 243.8 (165.0) | 201.1 (33.0) | 287.5 (179.5) | 294.6 (43.6) |
군 | YMT | SMT | S164 | |||
120 분 | 283.1 (93.1) | 161.5* (14.8) | 198.8 (70.5) | |||
군 | 성 | 동물 번호 | 에탄올(㎖/㎏) | AD 부피a) (㎖/㎏) | 복용량 (㎖/㎏) |
CON | 수컷 | 55 ~ 60 | 0 | 10 | 0 |
NCT | 수컷 | 61 ~ 66 | 10 | 10 | 0 |
SHT | 수컷 | 67 ~ 72 | 10 | 10 | 15 |
HST | 수컷 | 73 ~ 78 | 10 | 10 | 15 |
GMT | 수컷 | 79 ~ 84 | 10 | 10 | 15 |
CDT | 수컷 | 85 ~ 90 | 10 | 10 | 15 |
YMT | 수컷 | 91 ~ 96 | 10 | 10 | 15 |
SMT | 수컷 | 97 ~ 102 | 10 | 10 | 15 |
S164 | 수컷 | 103 ~ 108 | 10 | 10 | 15 |
성 | 수컷 | |||||
군 | CON | NCT | SHT | HST | GMT | CDT |
60% 에탄올(㎎/㎗) | 10 | 10 | 10 | 10 | 10 | 10 |
복용량(㎖/㎏) | 0 | 0 | 15 | 15 | 15 | 15 |
동물 수 | 6 | 6 | 6 | 6 | 6 | 6 |
240 분 | 28.0 (0.0) | 257.7 (55.4) | 226.4 (46.4) | 236.7 (47.5) | 207.8 (22.0) | 212.4 (36.6) |
군 | YMT | SMT | S164 | |||
240 분 | 209.6 (52.9) | 183.5* (24.6) | 172.3* (41.2) |
변수 | 성 | 수컷 | ||||
군 | CON | NCT | SHT | HST | GMT | |
에탄올(㎖/㎏) | 0 | 0 | 1.0 | 1.0 | 1.0 | |
복용량(㎖/㎏) | 0 | 0 | 15 | 15 | 15 | |
동물 수 | 6 | 6 | 6 | 6 | 6 | |
AST(lU/L)a) SDb ) | 170.1 (10.08) | 184.6 (40.43) | 158.3 (29.5) | 187.8 (38.3) | 146.5* (20.3) | |
ALT(lU/L)a) SD | 63.83 (7.93) | 83 (25.17) | 60.8* (5.07) | 66.5 (10.4) | 65.16 (10.18) | |
LDH(lU/L)a) SD | 1278 (372) | 1915.6 (828.8) | 1737 (664.9) | 2090.1 (242.3) | 1398.5 (607.2) | |
변수 | 성 | 수컷 | ||||
군 | CDT | YMT | SMT | S164 | ||
CCl4(㎖/㎏) | 1.0 | 1.0 | 1.0 | 1.0 | ||
복용량(㎖/㎏) | 15 | 15 | 15 | 15 | ||
동물 수 | 6 | 6 | 6 | 6 | ||
AST(lU/L)a) SDb ) | 166.1 (18.32) | 155.1 (18.97) | 169.1 (7.52) | 156.8 (19.03) | ||
ALT(lU/L)a) SD | 58.33* (8.61) | 58.16* (10.94) | 63.83 (2.85) | 61.16* (5.34) | ||
LDH(lU/L)a) SD | 1717.3 (503.8) | 1498.6 (328.8) | 1702.5 (357.7) | 1583.5 (605.5) |
변수 | 성 | 수컷 | ||||
군 | CON | NCT | SHT | HST | GMT | |
에탄올(㎖/㎏) | 0 | 0 | 1.0 | 1.0 | 1.0 | |
복용량(㎖/㎏) | 0 | 0 | 15 | 15 | 15 | |
동물 수 | 6 | 6 | 6 | 6 | 6 | |
AST(lU/L)a) SDb ) | 164.8 (16.94) | 153.7 (23.68) | 137.2 (11.23) | 151.7 (45.4) | 148.2 (20.7) | |
ALT(lU/L)a) SD | 62.5 (8.16) | 61.75 (6.55) | 55.0 (6.67) | 76.5 (20.01) | 55.6 (11.32) | |
LDH(lU/L)a) SD | 775.1 (236.1) | 881.7 (227.6) | 1033.4 (270.8) | 1048.5 (415.3) | 1380.8* (349.0) | |
변수 | 성 | 수컷 | ||||
군 | CDT | YMT | SMT | S164 | ||
CCl4(㎖/㎏) | 1.0 | 1.0 | 1.0 | 1.0 | ||
복용량(㎖/㎏) | 15 | 15 | 15 | 15 | ||
동물 수 | 6 | 6 | 6 | 6 | ||
AST(lU/L)a) SDb ) | 157.4 (61.45) | 163 (88.69) | 169.1 (7.52) | 149.5 (38.49) | ||
ALT(lU/L)a) SD | 59.0 (9.38) | 54.4 (11.61) | 63.83 (2.85) | 78.83 (28.28) | ||
LDH(lU/L)a) SD | 1247.4 (314.8) | 1142.4 (527.3) | 787.1 (202.1) | 739.16 (238.4) |
Claims (10)
- 백작약, 숙지황, 황기, 당귀, 천궁, 계피, 감초, 생강 및 대추로 이루어진 쌍화탕 성분에 지구자를 혼합하여 열수추출한 지구자를 포함하는 가미 쌍화탕을 함유하는 숙취해소용 조성물.
- 청구항 1에 있어서,백작약 10 중량부에 대하여, 지구자 10 내지 15, 숙지황 6 내지 17, 황기 6 내지 17, 당귀 6 내지 17, 천궁 6 내지 17, 계피 3 내지 14, 감초 3 내지 14, 생강 2 내지 14 및 대추 4 내지 8 중량부를 혼합하는 것을 특징으로 하는 조성물.
- 청구항 1에 있어서,상기 조성물은 알코올 섭취 전 또는 후에 혈액 내의 알코올 함량을 낮추는 것을 특징으로 하는 조성물.
- 청구항 1에 있어서,건강식품의 형태로 제공되는 것을 특징으로 하는 조성물.
- 백작약, 숙지황, 황기, 당귀, 천궁, 계피, 감초, 생강 및 대추를 혼합하여 열수추출한 쌍화탕에 유산균을 접종하여 발효시킴으로써 제조되는 것을 특징으로 하는 쌍화탕 유산균 발효물을 포함하는 숙취해소용 조성물.
- 청구항 5에 있어서,백작약 10 중량부에 대하여, 숙지황 6 내지 17, 황기 6 내지 17, 당귀 6 내지 17, 천궁 6 내지 17, 계피 3 내지 14, 감초 3 내지 14, 생강 2 내지 14 및 대추 4 내지 8 중량부를 혼합하는 것을 특징으로 하는 조성물.
- 청구항 5에 있어서,유산균은 락토바실러스 퍼멘텀(Lactobacillus fermentum), 락토바실러스 가세리(Lactobacillus gasseri), 락토바실러스 카세이(Lactobacillus casei), 락토바실러스 아시도필러스(Lactobacillus acidophilus), 락토바실러스 람노서스 (Lactobacillus rhamnosus)로 구성되는 군으로부터 선택되는 것을 특징으로 하는 조성물
- 청구항 5에 있어서,유산균은 락토바실러스 퍼멘텀(Lactobacillus fermentum)인 것을 특징으로 하는 조성물.
- 청구항 5에 있어서,상기 조성물은 알코올 섭취 전 또는 후에 혈액 내의 알코올 함량을 낮추는 것을 특징으로 하는 조성물.
- 청구항 5에 있어서,건강식품의 형태로 제공되는 것을 특징으로 하는 조성물.
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CN2008801183939A CN101878035B (zh) | 2007-11-30 | 2008-11-24 | 用于缓解酒精引起的宿醉的包含枳椇子的双和汤组合物 |
JP2010535873A JP5340302B2 (ja) | 2007-11-30 | 2008-11-24 | キグシを含む加味雙和湯を有効成分として含有する二日酔い解消用組成物 |
PCT/KR2008/006920 WO2009069921A2 (en) | 2007-11-30 | 2008-11-24 | Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang |
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KR101016606B1 (ko) * | 2009-12-07 | 2011-02-21 | 주식회사 엔유씨전자 | 헛개나무열매 발효물을 유효성분으로 하는 숙취해소 기능성 식품 |
KR101346244B1 (ko) * | 2011-06-30 | 2014-01-02 | 이철희 | 생약 제제를 포함하는 숙취 예방 또는 해소용 조성물 |
KR20180002922A (ko) * | 2016-06-29 | 2018-01-09 | 주식회사 농업회사법인비엔케어 | 프로폴리스를 이용한 숙취해소 음료 제조방법 |
KR20210073341A (ko) * | 2019-12-10 | 2021-06-18 | 안동대학교 산학협력단 | 간기능 개선에 효능이 있고, 기호성이 향상된 한약재 혼합 음료의 제조방법 및 이의 제조방법으로 제조된 음료 |
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JP2011136907A (ja) * | 2009-12-25 | 2011-07-14 | Kirin Holdings Co Ltd | 持久力向上剤 |
JP2012001511A (ja) * | 2010-06-18 | 2012-01-05 | Nitto Yakuhin Kogyo Kk | 配糖体分解用組成物 |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101016606B1 (ko) * | 2009-12-07 | 2011-02-21 | 주식회사 엔유씨전자 | 헛개나무열매 발효물을 유효성분으로 하는 숙취해소 기능성 식품 |
KR101346244B1 (ko) * | 2011-06-30 | 2014-01-02 | 이철희 | 생약 제제를 포함하는 숙취 예방 또는 해소용 조성물 |
KR20180002922A (ko) * | 2016-06-29 | 2018-01-09 | 주식회사 농업회사법인비엔케어 | 프로폴리스를 이용한 숙취해소 음료 제조방법 |
KR20210073341A (ko) * | 2019-12-10 | 2021-06-18 | 안동대학교 산학협력단 | 간기능 개선에 효능이 있고, 기호성이 향상된 한약재 혼합 음료의 제조방법 및 이의 제조방법으로 제조된 음료 |
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JP5340302B2 (ja) | 2013-11-13 |
WO2009069921A2 (en) | 2009-06-04 |
WO2009069921A3 (en) | 2009-08-13 |
KR101040721B1 (ko) | 2011-06-10 |
CN101878035A (zh) | 2010-11-03 |
JP2011505354A (ja) | 2011-02-24 |
CN101878035B (zh) | 2012-11-28 |
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