KR102168587B1 - Pet joint nutritional supplement composition - Google Patents
Pet joint nutritional supplement composition Download PDFInfo
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- A—HUMAN NECESSITIES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
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- A—HUMAN NECESSITIES
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- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/158—Fatty acids; Fats; Products containing oils or fats
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
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Abstract
Description
본 발명은 반려동물 관절 영양제 조성물에 관한 것이다.The present invention relates to a companion animal joint nutritional composition.
애완동물은 반려 동물로서 가족의 일원으로 인식되고 있다. 따라서 애완동물이 질병 없이 오래도록 함께 생활하는 것은 애완동물을 키우는 가정의 행복을 위하여 중요한 일이 되고 있다. Pets are recognized as companion animals and members of the family. Therefore, it has become an important task for the happiness of families with pets to live together for a long time without diseases.
포유동물의 노령에 동반하는 질병으로는 관절장애와 혈관계 이상, 각종 암 발생 등을 들 수 있으며, 이들이 복합적인 병증으로 나타난다. 따라서 애완동물을 키우는 사람들은 이러한 노환에 따르는 치료비용, 안락사 처리 등에 따르는 심리적, 경제적 고충을 겪게 된다. Diseases associated with the aging of mammals include joint disorders, vascular system abnormalities, and the occurrence of various cancers, and these appear as complex conditions. Therefore, people with pets suffer psychological and economic hardships related to the treatment costs and euthanasia treatments associated with old age.
애완동물에 발생하는 관절질환의 경우 일반적으로 포유류와 사람에게서 발생하는 류머티즘성 관절염, 골 관절염, 과도한 운동에 의한 관절염, 관절 주위염, 변형성 관절증 등의 다양한 형태로 나타난다. 특히 노령 견과 같은 애완동물의 경우 골관절염, 관절 주위염이 주요 질병으로 많이 발생한다.In the case of joint disease that occurs in pets, it appears in various forms, such as rheumatoid arthritis, osteoarthritis, arthritis due to excessive exercise, periarthritis, and deformed arthritis that occur in mammals and humans. In particular, in pets such as elderly dogs, osteoarthritis and periarthritis are common diseases.
이런 관절질환과 관련하여 좋은 치료를 통한 완치는 차선책이고 가장 좋은 선택은 병증이 발생하기 전에 예방하고 완화시킬 수 있는 방법을 찾는 것이다. 노령의 애완동물의 관절장애에 대한 치료에는 보통 글루코사민이나 콘드로이친황산 등이 이용되고 있다. 또한, 최근에는 메틸설포닐메탄(MSM)이 관절 영양제의 주성분으로 사용되고 있다. Regarding these joint diseases, cure through good treatment is the next best option, and the best option is to find a way to prevent and alleviate the condition before it develops. In the treatment of joint disorders in elderly pets, glucosamine or chondroitin sulfate is usually used. In addition, recently, methylsulfonylmethane (MSM) has been used as a major component of joint nutrition.
그러나, 이러한 노령 애완동물의 관절질환을 예방하고 치료할 수 있는 신뢰할 수 있는 영양제는 아직 충분히 공급되고 있지 못한 실정이다. However, a reliable nutrient that can prevent and treat joint diseases in these elderly pets is not yet sufficiently supplied.
본 발명은 종래기술의 상기와 같은 문제를 해결하기 위하여 안출된 것으로서, The present invention was devised to solve the above problems of the prior art,
반려동물의 관절질환을 부작용 없이 효과적으로 예방 및 치료할 수 있어서 믿고 사용할 수 있는 반려동물의 관절 영양제 조성물을 제공하는 것을 목적으로 한다. An object of the present invention is to provide a joint nutrient composition for companion animals that can be trusted and used because it can effectively prevent and treat joint diseases of companion animals without side effects.
상기 목적을 달성하기 위하여, 본 발명은In order to achieve the above object, the present invention
본 발명은 조성물 총 중량에 대하여, 메틸설포닐메탄(MSM) 20 내지 35 중량%; N-아세틸글루코사민 5 내지 15 중량%; 초록입홍합 1 내지 10 중량%; 뮤코다당단백 2 내지 7 중량%; 오메가3 분말(DHA/EPA) 1 내지 10 중량%; 건조효모 1 내지 10 중량%; 가수분해 연어분말 1 내지 15 중량%; 프락토올리고당 1 내지 10 중량%; 포도당 1 내지 10 중량%; 결정셀룰로오스 1 내지 15 중량%; 및 치즈향 0.2 내지 3 중량%;를 포함하는 반려동물 관절 영양제 조성물을 제공한다.The present invention, based on the total weight of the composition, methylsulfonylmethane (MSM) 20 to 35% by weight; 5 to 15% by weight of N-acetylglucosamine; 1 to 10% by weight of green lipped mussels; 2 to 7% by weight of mucopolysaccharide; 1 to 10% by weight of omega 3 powder (DHA/EPA); 1 to 10% by weight of dry yeast; 1 to 15% by weight of hydrolyzed salmon powder; 1 to 10% by weight of fructooligosaccharide; 1 to 10% by weight of glucose; 1 to 15% by weight of crystalline cellulose; And cheese flavor 0.2 to 3% by weight; It provides a companion animal joint nutritional composition comprising.
본 발명의 반려동물의 관절 영양제 조성물은 부작용 없이 반려동물의 관절질환을 효과적으로 예방 및 치료할 수 있는 효과를 제공한다.The joint nutritional composition for companion animals of the present invention provides an effect that can effectively prevent and treat joint diseases in companion animals without side effects.
이하에서 본 발명을 자세하게 설명한다. Hereinafter, the present invention will be described in detail.
본 발명은 조성물 총 중량에 대하여, 메틸설포닐메탄(MSM) 20 내지 35 중량%; N-아세틸글루코사민 5 내지 15 중량%; 초록입홍합 1 내지 10 중량%; 뮤코다당단백 2 내지 7 중량%; 오메가3 분말(DHA/EPA) 1 내지 10 중량%; 건조효모 1 내지 10 중량%; 가수분해 연어분말 1 내지 15 중량%; 프락토올리고당 1 내지 10 중량%; 포도당 1 내지 10 중량%; 결정셀룰로오스 1 내지 15 중량%; 및 치즈향 0.2 내지 3 중량%;를 포함하는 반려동물 관절 영양제 조성물에 관한 것이다.The present invention, based on the total weight of the composition, methylsulfonylmethane (MSM) 20 to 35% by weight; 5 to 15% by weight of N-acetylglucosamine; 1 to 10% by weight of green lipped mussels; 2 to 7% by weight of mucopolysaccharide; 1 to 10% by weight of omega 3 powder (DHA/EPA); 1 to 10% by weight of dry yeast; 1 to 15% by weight of hydrolyzed salmon powder; 1 to 10% by weight of fructooligosaccharide; 1 to 10% by weight of glucose; 1 to 15% by weight of crystalline cellulose; And cheese flavor 0.2 to 3% by weight; It relates to a companion animal joint nutritional composition comprising.
상기 메틸설포닐메탄(MSM)은 관절 영양제의 주성분으로 사용된다. 상기 MSM은 보통 원산지가 전부 다르며, 이 MSM은 일반 결정화 정제법으로 추출된다. 상기 결정화 정제법은 MSM을 제조할 때 중금속에 오염되는 다량의 물이 사용되기 때문에 중금속 오염의 문제가 있고 순도도 검증되지 않는 경우도 많다.The methylsulfonylmethane (MSM) is used as a main component of joint nutrition. The MSM usually has all different origins, and this MSM is extracted by a general crystallization purification method. In the crystallization purification method, since a large amount of water contaminated with heavy metals is used when preparing MSM, there is a problem of heavy metal contamination and purity is often not verified.
따라서, 본 발명에서는 미국에서 인증 받은 OptiMSM(Bergstrom Nutrition사에서 생산)이 바람직하게 사용된다. 상기 OptiMSM은 증류정제법으로 천연펄프에서 추출해 중금속 오염에서 자유롭고 순도도 최소 99.8%로서 우수하다. 또한, 글루텐이나 알레르기, 갑각류 성분이 없다.Therefore, in the present invention, OptiMSM (produced by Bergstrom Nutrition) certified in the United States is preferably used. The OptiMSM is extracted from natural pulp by distillation and refining and is free from heavy metal contamination and has an excellent purity of at least 99.8%. It is also free of gluten, allergy, and shellfish.
상기 뮤코다당단백은 콘드로이친을 함유하는 성분이다. The mucopolysaccharide protein is a component containing chondroitin.
상기 영양제 조성물은 식물발효물 1 내지 10 중량%를 더 포함하며, The nutrient composition further comprises 1 to 10% by weight of plant fermentation,
상기 식물발효물은The plant fermentation product is
a) 해변씨레네(Silene villosa), 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)을 1~3 : 1~3 : 1~3의 중량비로 혼합한 식물 혼합물을 잘게 썰은 후 발효용기에 넣는 단계;a) The step of chopping the plant mixture mixed with the weight ratio of 1 to 3: 1 to 3: 1 to 3 of Silene villosa, Nopal, and Lathyrus sativus, and putting it into a fermentation container ;
b) 상기 발효용기에 무화과 농축액을 첨가하고, 젖산균 및 효모 중의 1종 이상의 균주를 접종하고 2주 내지 3개월 간 발효시키는 단계; b) adding fig concentrate to the fermentation vessel, inoculating at least one strain of lactic acid bacteria and yeast, and fermenting for 2 weeks to 3 months;
c) 상기 b)단계의 발효물을 슬러리 상태로 제조하는 단계; 및c) preparing the fermented product of step b) in a slurry state; And
d) 상기 c)단계의 슬러리를 건조하여 분말을 제조하는 단계;를 포함하여 제조된 것을 특징으로 한다.d) drying the slurry of step c) to prepare a powder.
상기 a) 단계의 해변씨레네(Silene villosa)는 사막 식물로서 지중해 연변 모래사장에서 자라는 것으로 알려져 있다. 본 발명자들은 상기 해변씨레네가 관절염 억제 활성을 갖는 것을 확인하였다. 본 발명에서 해변씨레네의 꽃, 줄기, 잎이 모두 사용될 수 있다.The beach sirene (Silene villosa) of step a) is a desert plant and is known to grow on sandy beaches along the Mediterranean Sea. The present inventors confirmed that the beach sirene has arthritis inhibitory activity. In the present invention, flowers, stems, and leaves of seaside siren may be used.
또한, 본 발명자들은 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)이 관절염에 억제 활성을 갖는 것을 확인하고, 특히, 해변씨레네와 조합하여 발효시켜 사용할 경우 우수한 효과를 제공하는 것을 발견하여 본 발명을 완성하였다.In addition, the inventors of the present invention confirmed that Nopal and grass peas (Lathyrus sativus) have inhibitory activity against arthritis, and in particular, found that they provide excellent effects when fermented in combination with seaside cinene. Was completed.
본 발명에서는 상기 해변씨레네(Silene villosa), 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)의 관절염 활성을 향상시키기 위하여 상기 성분들의 혼합물을 발효시켜서 사용한다. In the present invention, a mixture of the above ingredients is fermented and used in order to improve the arthritis activity of the seaside sirene (Silene villosa), Nopal (Nopal), and grass pea (Lathyrus sativus).
본 발명은 상기 식물 혼합물 100 중량부를 기준으로 관절염의 활성을 증가시키기 위하여 브로콜리 1~10 중량부, 초석잠 1~10 중량부, 케이퍼 1~10 중량% 및 수염가래꽃 1~10 중량부를 더 포함할 수 있다. In order to increase the activity of arthritis based on 100 parts by weight of the plant mixture, the present invention further comprises 1 to 10 parts by weight of broccoli, 1 to 10 parts by weight of Choseokjam, 1 to 10 parts by weight of capers and 1 to 10 parts by weight of sputum flowers Can include.
상기 브로콜리, 초석잠, 케이퍼, 및 수염가래꽃은 상기 식물 혼합물의 관절염 억제 활성을 향상시키는 기능을 수행한다.The broccoli, choseokjam, caper, and sputum sputum function to enhance the arthritis inhibitory activity of the plant mixture.
상기 케이퍼는 본래 지중해 연안에서 자생하는 식물이며, 이 식물의 꽃봉오리를 채취해서 가공해 향신료로 사용하거나, 식초에 절여서 피클 형태로 만들어 사용하는 식물이다. 본 발명자들은 상기 케이퍼가 관절염의 억제 활성이 우수한 것을 확인하여 본 발명에 사용하였다. The caper is a plant native to the Mediterranean coast, and is a plant used as a spice by collecting and processing the buds of this plant, or pickling it in vinegar to form a pickle. The present inventors confirmed that the caper has an excellent inhibitory activity against arthritis and used it in the present invention.
상기 수염가래꽃은 한의학에서 생약으로 사용되고 있는 약용식물로서 다양한 생리활성물질을 함유하고 있다. 수염가래꽃은 반변련, 반변란 또는 급해색이라고 불리며 국내에서는 중부 이남과 제주도에 분포하고 도랑이나 냇가, 논두렁의 습지에서 서식하고 있다. 수염가래꽃은 전통적으로 이뇨, 소염, 해독 등의 효능을 가지고 있으며 천식, 호흡곤란, 백일해, 악성종기, 습진, 외상출혈을 치료하는 약재로 사용되었다. 본 발명자들은 수염가래꽃이 관절염에 대한 활성을 갖는 것을 발견하여 첨가하고 있다. The beard sputum flower is a medicinal plant used as a herbal medicine in oriental medicine and contains various physiologically active substances. Bearded sputum flowers are called Banbyeon, Banbyeonran, or Sudden Sea Color. In Korea, it is distributed in the south of the central region and Jeju Island, and lives in ditches, streams, and wetlands of rice fields. The sputum sputum has traditionally been used as a medicine to treat asthma, dyspnea, whooping cough, malignant boils, eczema, and traumatic bleeding. The present inventors have discovered and added that the sputum sputum has an activity against arthritis.
상기 식물발효에 사용가능한 상기 젖산균은 락토바실루스속 젖산균(Lactobacillus sp.), 스트렙토코쿠스속 젖산균(Streptococcus sp.), 페디오코쿠스속 젖산균(Pediococcus sp.), 류코노스톡속 젖산균(Leuconostoc sp.), 비피도박테리움속 젖산균(Bifidobacterium sp.) 등일 수 있다.The lactic acid bacteria that can be used in the plant fermentation include Lactobacillus sp., Streptococcus sp., Pediococcus sp., and Leukonostoc sp. ), Bifidobacterium sp., and the like.
또한, 상기 효모로는 사카로마이세스 세레비시아에(Saccharomyces sereviciae), 사카로마이세스 루시(Saccharomyces rouxii), 사카로마이세스 오비폴미스(Saccharomyces oviformis), 사카로마이세스 스테이네리(Saccharomyces steineri) 등이 사용될 수 있다.In addition, as the yeast, Saccharomyces sereviciae (Saccharomyces sereviciae), Saccharomyces rouxii, Saccharomyces oviformis (Saccharomyces oviformis), Saccharomyces steineri (Saccharomyces steineri) ), etc. may be used.
본 발명에서 당으로는 무화과 농축액이 식물 혼합물 100 중량부에 대하여 5 내지 30 중량부로 사용될 수 있다. In the present invention, the fig concentrate may be used in an amount of 5 to 30 parts by weight based on 100 parts by weight of the plant mixture as sugar.
이하에서, 실시예를 통하여 본 발명을 보다 상세히 설명한다. 그러나, 하기의 실시예는 본 발명을 더욱 구체적으로 설명하기 위한 것으로서, 본 발명의 범위가 하기의 실시예에 의하여 한정되는 것은 아니다. 하기의 실시예는 본 발명의 범위 내에서 당업자에 의해 적절히 수정, 변경될 수 있다. Hereinafter, the present invention will be described in more detail through examples. However, the following examples are for explaining the present invention more specifically, and the scope of the present invention is not limited by the following examples. The following examples can be appropriately modified and changed by those skilled in the art within the scope of the present invention.
제조예 1: 식물발효물의 제조Preparation Example 1: Preparation of plant fermentation
해변씨레네(Silene villosa), 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)을 2 : 1 : 1의 중량비로 혼합한 식물 혼합물 1 kg을 잘게 썰은 후 발효용기인 항아리에 넣었다. 상기 항아리에 무화과 농축액 총 200 g을 넣어주었다. 그 다음 Streptococcus sp.균주를 접종하고, 공기가 통할 수 있게 항아리를 봉하여 상온의 그늘에서 1개월 간 발효시켰다. 상기 발효물을 분쇄기로 분쇄하여 슬러리 상태로 만들고 건조하여 분말 상태로 제조하였다. 1 kg of a plant mixture obtained by mixing Silene villosa, Nopal, and Lathyrus sativus at a weight ratio of 2:1:1 was chopped and placed in a fermentation container. A total of 200 g of fig concentrate was put in the jar. Then, Streptococcus sp. strain was inoculated, the jar was sealed to allow air to pass through, and fermented in the shade at room temperature for 1 month. The fermented product was pulverized with a grinder to form a slurry, and dried to prepare a powder state.
제조예 2: 식물발효물의 제조Preparation Example 2: Preparation of plant fermentation
해변씨레네(Silene villosa), 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)을 2 : 1 : 1의 중량비로 혼합한 식물 혼합물 1 kg을 잘게 썰은 후 발효용기인 항아리에 넣었다. 상기 항아리에 브로콜리 30 g, 초석잠 30 g, 케이퍼 30 g 및 수염가래꽃 30 g를 넣고, 무화과 농축액 총 200 g을 넣어주었다. 그 다음 Streptococcus sp.균주를 접종하고, 공기가 통할 수 있게 항아리를 봉하여 상온의 그늘에서 1개월 간 발효시켰다. 상기 발효물을 분쇄기로 분쇄하여 슬러리 상태로 만들고 건조하여 분말 상태로 제조하였다. 1 kg of a plant mixture obtained by mixing Silene villosa, Nopal, and Lathyrus sativus at a weight ratio of 2:1:1 was chopped and placed in a fermentation container. 30 g of broccoli, 30 g of choseokjam, 30 g of capers and 30 g of sputum flowers were put in the jar, and a total of 200 g of fig concentrate was added. Then, Streptococcus sp. strain was inoculated, the jar was sealed to allow air to pass through, and fermented in the shade at room temperature for 1 month. The fermented product was pulverized with a grinder to form a slurry, and dried to prepare a powder state.
실시예 1: 반려동물 관절 영양제 조성물Example 1: Companion animal joint nutrition composition
메틸설포닐메탄(OptiMSM) 31 중량%; N-아세틸글루코사민 11 중량%; 초록입홍합 8 중량%; 뮤코다당단백 8 중량%; 오메가3 분말 7 중량%; 건조효모 4.5 중량%; 가수분해 연어분말 10 중량%; 프락토올리고당 5 중량%; 포도당 5 중량%; 결정셀룰로오스 10 중량%; 및 치즈향 0.5 중량%;를 혼합하여 관절 영양제 조성물을 제조하였다.31% by weight of methylsulfonylmethane (OptiMSM); 11% by weight of N-acetylglucosamine; 8% green lipped mussels; 8% by weight of mucopolysaccharide; 7% by weight of omega 3 powder; 4.5% by weight of dry yeast; 10% by weight of hydrolyzed salmon powder; 5% by weight of fructooligosaccharide; 5% by weight of glucose; 10% by weight of crystalline cellulose; And cheese flavor 0.5% by weight; by mixing to prepare a joint nutritional composition.
실시예 2: 반려동물 관절 영양제 조성물Example 2: Companion animal joint nutrition composition
메틸설포닐메탄(OptiMSM) 30 중량%; N-아세틸글루코사민 10 중량%; 초록입홍합 7 중량%; 뮤코다당단백 7 중량%; 오메가3 분말 6 중량%; 건조효모 4.5 중량%; 가수분해 연어분말 10 중량%; 프락토올리고당 5 중량%; 포도당 5 중량%; 결정셀룰로오스 10 중량%; 상기 제조예 1에서 제조된 식물발효물 5 중량%; 및 치즈향 0.5 중량%;를 혼합하여 관절 영양제 조성물을 제조하였다.30% by weight of methylsulfonylmethane (OptiMSM); 10% by weight of N-acetylglucosamine; 7% by weight green lipped mussel; 7% by weight of mucopolysaccharide; 6% by weight of omega 3 powder; 4.5% by weight of dry yeast; 10% by weight of hydrolyzed salmon powder; 5% by weight of fructooligosaccharide; 5% by weight of glucose; 10% by weight of crystalline cellulose; 5% by weight of the plant fermentation product prepared in Preparation Example 1; And cheese flavor 0.5% by weight; by mixing to prepare a joint nutritional composition.
실시예 3: 반려동물 관절 영양제 조성물Example 3: Companion Animal Joint Nutritional Supplement Composition
메틸설포닐메탄(OptiMSM) 30 중량%; N-아세틸글루코사민 10 중량%; 초록입홍합 7 중량%; 뮤코다당단백 7 중량%; 오메가3 분말 6 중량%; 건조효모 4.5 중량%; 가수분해 연어분말 10 중량%; 프락토올리고당 5 중량%; 포도당 5 중량%; 결정셀룰로오스 10 중량%; 상기 제조예 2에서 제조된 식물발효물 5 중량%; 및 치즈향 0.5 중량%;를 혼합하여 관절 영양제 조성물을 제조하였다.30% by weight of methylsulfonylmethane (OptiMSM); 10% by weight of N-acetylglucosamine; 7% by weight green lipped mussel; 7% by weight of mucopolysaccharide; 6% by weight of omega 3 powder; 4.5% by weight of dry yeast; 10% by weight of hydrolyzed salmon powder; 5% by weight of fructooligosaccharide; 5% by weight of glucose; 10% by weight of crystalline cellulose; 5% by weight of the plant fermentation product prepared in Preparation Example 2; And cheese flavor 0.5% by weight; by mixing to prepare a joint nutritional composition.
시험예 1: 반려동물 관절 영양제 조성물의 영양성분 분석Test Example 1: Analysis of Nutritional Components of Companion Animal Joint Nutritional Composition
상기 실시예 1에서 제조된 영양제 조성물의 영양성분은 다음 표 1에 나타낸 바와 같이 분석되었다. The nutritional components of the nutritional composition prepared in Example 1 were analyzed as shown in Table 1 below.
시험예 2: 반려동물 관절 영양제 조성물의 관절염 억제 작용 평가Test Example 2: Evaluation of Arthritis Inhibitory Activity of Companion Animal Joint Nutrient Composition
관절염 억제 작용을 마우스 콜라겐 유도성 관절염 모델[네이쳐(Nature), 1980년, 제283권, p.666-668]을 이용하여 시험하였다.The arthritis inhibitory action was tested using a mouse collagen-induced arthritis model [Nature, 1980, Vol. 283, p.666-668].
6주령의 수컷 DBA/1J 마우스(찰스 리버사 제조)에 제1 2형 콜라겐 투여로서 2형 콜라겐(콜라겐 기술 연수회사 제조)과 프로인트 완전 보조제(Freund's complete adjuvant, 야토론사 제조)를 등량으로 혼합하여 균질기로 에멀젼화시킨 용액을 1 마리당 100 ㎕씩 꼬리 부분에 피부내 투여하였다. 제1 2형 콜라겐을 투여한지 21 일 후에, 제2 2형 콜라겐 투여로서, 동일하게 2형 콜라겐과 프로인트 완전 보조제를 등량으로 혼합하여 균질기로 에멀젼화시킨 용액을 1 마리당 100 ㎕씩 꼬리부분에 피부내 투여하였다.Type 2 collagen (manufactured by collagen technology training company) and Freund's complete adjuvant (manufactured by Yatoron) in equal amounts as type 2 collagen administration to 6-week-old male DBA/1J mice (manufactured by Charles River) The mixed and emulsified solution with a homogenizer was administered intradermally to the tail at 100 µl per animal. Twenty-one days after the administration of type 2 collagen 1, as type 2 collagen administration, a solution obtained by mixing equal amounts of type 2 collagen and Freund's complete adjuvant and emulsifying it with a homogenizer was added to the tail at a rate of 100 µl per animal. It was administered intradermally.
제1 2형 콜라겐 투여일로부터, 비교군의 마우스에게는 시판 분말 사료 CE-2(닛본 구레아사 제조)를, 실험 1군의 마우스에게는 실시예 1에서 제조한 관절 영양제 조성물을 0.5 중량% 첨가한 CE-2를, 실험 2군의 마우스에게는 실시예 2에서 제조한 관절 영양제 조성물을 0.5 중량% 첨가한 CE-2를, 실험 3군의 마우스에게는 실시예 3에서 제조한 관절 영양제 조성물을 0.5 중량% 첨가한 CE-2를 각각 섭취시켰다. 또한, 2형 콜라겐을 투여하지 않은 무처리군에도 CE-2를 섭취시켰다.From the day of administration of type 1 collagen 2, a commercial powdered feed CE-2 (manufactured by Nippon Gurea) was added to the mice of the control group, and 0.5% by weight of the joint nutritional composition prepared in Example 1 was added to the mice of the experiment group 1. -2, CE-2, prepared by adding 0.5% by weight of the joint nutritional composition prepared in Example 2 to the mice of the experimental group 2, and 0.5% by weight, to the mice of the experimental group 3, added the joint nutritional composition prepared in Example 3 One CE-2 was taken each. In addition, CE-2 was also taken into the untreated group to which type 2 collagen was not administered.
제1 2형 콜라겐을 투여한 후 27, 30, 34 일째에, 관절염의 발증 정도를 이하와 같은 지표에 의해서 스코어링하였다. 마우스의 손 또는 발 하나에 대하여,On the 27th, 30th, and 34th days after administration of type 2 collagen, the degree of onset of arthritis was scored by the following indicators. For one hand or foot of the mouse,
0 점: 무증상, 0 points: asymptomatic,
1 점: 손가락 1개 부종, 또는 손(발)목 경도의 부종, 1 point: swelling of one finger, or swelling of the hand (foot) and neck,
2 점: 손가락 1 내지 3개의 부종, 또는 손(발)목의 부종, 2 points: swelling of 1 to 3 fingers, or swelling of the neck of the hand (foot),
3 점: 손가락 3 내지 5개 부종 + 손(발)목의 부종, 3 points: swelling of 3 to 5 fingers + swelling of the hands (foot) and neck,
4 점: 손가락 전부 부종 + 손(발)목의 부종4 points: swelling of all fingers + swelling of hands (foot) and neck
을 기준으로 0 점 내지 4 점으로 스코어링하였다. 마우스 1 마리에 대하여 손발 4개 스코어의 합계점, 즉 0 점 내지 16 점으로 스코어링하였다. 값은 평균치±표준 오차(N=20)로 나타내었다.Scored from 0 to 4 points based on. One mouse was scored as a total score of 4 limbs, that is, 0 to 16 points. Values are expressed as mean ± standard error (N=20).
관절염 스코어의 결과를 표 2에 나타내었다.Table 2 shows the results of the arthritis score.
무처리군Collagen
Untreated group
상기 표 1에서 확인되는 바와 같이, 본 발명의 실시예 1 내지 3의 관절 영양제 조성물을 사료(CE-2)와 함께 투여한 실험 1군 내지 3군은 사료(CE-2)만 투여한 비교군과 비교하여 관절염 발생 수치가 매우 낮았다. 특히, 실험 2군 및 3군은 비교군과 비교하여 현저하게 관절염 수치가 낮아진 결과를 나타냈다. As shown in Table 1, the experimental groups 1 to 3 in which the joint nutritional composition of Examples 1 to 3 of the present invention was administered together with feed (CE-2) was a comparative group administered only feed (CE-2). The incidence of arthritis was very low compared to. In particular, the experimental groups 2 and 3 showed remarkably lower levels of arthritis compared to the comparison group.
Claims (4)
상기 영양제 조성물은 식물발효물 3 내지 7 중량%를 더 포함하며, 상기 식물발효물은 a) 해변씨레네(Silene villosa), 노팔(Nopal), 및 잔디완두콩(Lathyrus sativus)을 1~3 : 1~3 : 1~3의 중량비로 혼합한 식물 혼합물을 잘게 썰은 후 발효용기에 넣는 단계; b) 상기 발효용기에 무화과 농축액을 첨가하고, 젖산균 및 효모 중의 1종 이상의 균주를 접종하고 2주 내지 3개월 간 발효시키는 단계; c) 상기 b)단계의 발효물을 슬러리 상태로 제조하는 단계; 및 d) 상기 c)단계의 슬러리를 건조하여 분말을 제조하는 단계;를 포함하여 제조된 것을 특징으로 하는 반려동물 관절 영양제 조성물.Based on the total weight of the composition, methylsulfonylmethane (MSM) 28 to 33% by weight; 8 to 13% by weight of N-acetylglucosamine; 6 to 9% by weight of green lipped mussels; 5 to 7% by weight of mucopolysaccharide; 5 to 8% by weight of omega 3 powder; 3 to 5% by weight of dry yeast; 8 to 12% by weight of hydrolyzed salmon powder; 3 to 7% by weight of fructooligosaccharide; 3 to 7 weight percent glucose; 8 to 12% by weight of crystalline cellulose; And as a companion animal joint nutritional composition comprising a cheese flavor 0.2 to 1% by weight,
The nutrient composition further comprises 3 to 7% by weight of plant fermentation, and the plant fermentation is 1 to 3: 1 of a) Seaside villosa, Nopal, and Lathyrus sativus. ~3: chopping the mixed plant mixture at a weight ratio of 1 to 3 and placing it in a fermentation container; b) adding fig concentrate to the fermentation vessel, inoculating at least one strain of lactic acid bacteria and yeast, and fermenting for 2 weeks to 3 months; c) preparing the fermented product of step b) in a slurry state; And d) drying the slurry of step c) to prepare a powder; Companion animal joint nutritional supplement composition comprising the.
상기 a) 단계에서 상기 식물 혼합물 100 중량부에 대하여 브로콜리 1~10 중량부, 초석잠 1~10 중량부, 케이퍼 1~10 중량부 및 수염가래꽃 1~10 중량부를 발효용기에 더 첨가하는 것을 특징으로 하는 반려동물 관절 영양제 조성물.The method of claim 1,
In step a) further adding 1 to 10 parts by weight of broccoli, 1 to 10 parts by weight of Choseokjam, 1 to 10 parts by weight of capers and 1 to 10 parts by weight of sputum flowers to the fermentation vessel based on 100 parts by weight of the plant mixture Companion animal joint nutrition composition, characterized in that.
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---|---|---|---|---|
KR102287247B1 (en) | 2020-12-24 | 2021-08-06 | 양소현 | The composition of joint nutritional supplement for companion animals |
KR102432654B1 (en) * | 2021-08-31 | 2022-08-16 | 주식회사 캘러스 | Feed additives for improve joint disease in companion animal |
KR102567940B1 (en) * | 2022-03-18 | 2023-08-18 | 주식회사 마르켄9 | Daily nutritional supplement for pets with increased palatability |
KR102567938B1 (en) * | 2022-03-18 | 2023-08-18 | 주식회사 마르켄9 | Lactic acid bacteria freeze-drying method of dog nutritious snack |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080069862A1 (en) * | 2006-09-15 | 2008-03-20 | Marni Markell Hurwitz | Joint preserving nutritional vitamin, mineral and herbal pet supplement |
JP2014507411A (en) * | 2011-01-10 | 2014-03-27 | イーエスエム テクノロジーズ リミテッド ライアビリティ カンパニー | Dietary supplements to promote bone and joint growth, recovery, and maintenance |
KR101559515B1 (en) | 2014-10-10 | 2015-10-15 | 건국대학교 산학협력단 | Composition of the functional feed additive |
KR20170050011A (en) * | 2015-10-29 | 2017-05-11 | (주)푸른가족 농업회사법인 | Composition of Gruel for the Prevention of Joint Pathologies and Manufacturing Method thereof |
KR101919759B1 (en) * | 2018-07-31 | 2018-11-19 | 이대훈 | Composition for preventing or improving bone-related disease comprising polysaccharide purified from seaweed extract as effective component |
KR20190027434A (en) * | 2017-09-07 | 2019-03-15 | 주식회사 알파벳 | Manufacturing Method of a Pet Food for Improving Palatability and Storage Stability |
-
2020
- 2020-04-29 KR KR1020200052243A patent/KR102168587B1/en active IP Right Grant
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080069862A1 (en) * | 2006-09-15 | 2008-03-20 | Marni Markell Hurwitz | Joint preserving nutritional vitamin, mineral and herbal pet supplement |
JP2014507411A (en) * | 2011-01-10 | 2014-03-27 | イーエスエム テクノロジーズ リミテッド ライアビリティ カンパニー | Dietary supplements to promote bone and joint growth, recovery, and maintenance |
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