JPWO2021064998A1 - - Google Patents

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Publication number
JPWO2021064998A1
JPWO2021064998A1 JP2020570986A JP2020570986A JPWO2021064998A1 JP WO2021064998 A1 JPWO2021064998 A1 JP WO2021064998A1 JP 2020570986 A JP2020570986 A JP 2020570986A JP 2020570986 A JP2020570986 A JP 2020570986A JP WO2021064998 A1 JPWO2021064998 A1 JP WO2021064998A1
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JP
Japan
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Application number
JP2020570986A
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JP7014469B2 (ja
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Publication of JPWO2021064998A1 publication Critical patent/JPWO2021064998A1/ja
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Publication of JP7014469B2 publication Critical patent/JP7014469B2/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/32Special delivery means, e.g. tissue-specific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020570986A 2019-10-04 2019-10-04 3次元流路構造体およびこれを用いたナノ粒子の製造方法 Active JP7014469B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2019/039347 WO2021064998A1 (ja) 2019-10-04 2019-10-04 3次元流路構造体およびこれを用いたナノ粒子の製造方法

Publications (2)

Publication Number Publication Date
JPWO2021064998A1 true JPWO2021064998A1 (ja) 2021-04-08
JP7014469B2 JP7014469B2 (ja) 2022-02-01

Family

ID=75336865

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020570986A Active JP7014469B2 (ja) 2019-10-04 2019-10-04 3次元流路構造体およびこれを用いたナノ粒子の製造方法

Country Status (4)

Country Link
US (1) US20220370351A1 (ja)
JP (1) JP7014469B2 (ja)
CN (1) CN114502269A (ja)
WO (1) WO2021064998A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023153404A1 (ja) * 2022-02-08 2023-08-17 国立大学法人北海道大学 流路構造体およびこれを用いた自己組織化物質粒子の製造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009505957A (ja) * 2005-07-27 2009-02-12 プロチバ バイオセラピューティクス インコーポレイティッド リポソームの製造システムおよび製造方法
JP2014511687A (ja) * 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
JP2016535738A (ja) * 2013-10-22 2016-11-17 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド メッセンジャーrnaの送達のための脂質製剤
JP2021511376A (ja) * 2018-01-18 2021-05-06 イーザアールエヌーエー イムノセラピーズ エンヴェー 脂質ナノ粒子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1380132A (zh) * 2002-03-22 2002-11-20 上海交通大学 脂质体与无机材料的核-壳式纳米复合粒子及其制备方法和应用
CN107028886A (zh) * 2009-11-04 2017-08-11 不列颠哥伦比亚大学 含有核酸的脂质粒子及相关的方法
CA3059714C (en) * 2017-04-13 2023-02-14 National University Corporation Hokkaido University Flow channel structure and lipid particle or micelle formation method using same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009505957A (ja) * 2005-07-27 2009-02-12 プロチバ バイオセラピューティクス インコーポレイティッド リポソームの製造システムおよび製造方法
JP2014511687A (ja) * 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
JP2016535738A (ja) * 2013-10-22 2016-11-17 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド メッセンジャーrnaの送達のための脂質製剤
JP2021511376A (ja) * 2018-01-18 2021-05-06 イーザアールエヌーエー イムノセラピーズ エンヴェー 脂質ナノ粒子

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANSARI MUBASHSHIR AHMAD ET AL.: "Parametric study on mixing of two fluids in a three-dimensional serpentine microchannel", CHEMICAL ENGINEERING JOURNAL, vol. 146, JPN6019043616, 2009, pages 439 - 448, XP025883081, ISSN: 0004662641, DOI: 10.1016/j.cej.2008.10.006 *
KIMURA NIKO ET AL.: "Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10nm for Drug Delive", ACS OMEGA, vol. 3, JPN6019043614, 9 May 2018 (2018-05-09), pages 5044 - 5051, XP055810726, ISSN: 0004662639, DOI: 10.1021/acsomega.8b00341 *
LIU ROBIN H. ET AL.: "Passive Mixing in a Three-Dimensional Serpentine Microchannel", JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, vol. 9, no. 2, JPN6019043615, 2000, pages 190 - 197, ISSN: 0004662640 *

Also Published As

Publication number Publication date
WO2021064998A1 (ja) 2021-04-08
JP7014469B2 (ja) 2022-02-01
US20220370351A1 (en) 2022-11-24
CN114502269A (zh) 2022-05-13

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