JPWO2005074960A1 - 機能性飲料及び組成物 - Google Patents
機能性飲料及び組成物 Download PDFInfo
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- JPWO2005074960A1 JPWO2005074960A1 JP2005517749A JP2005517749A JPWO2005074960A1 JP WO2005074960 A1 JPWO2005074960 A1 JP WO2005074960A1 JP 2005517749 A JP2005517749 A JP 2005517749A JP 2005517749 A JP2005517749 A JP 2005517749A JP WO2005074960 A1 JPWO2005074960 A1 JP WO2005074960A1
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- Prior art keywords
- allergic rhinitis
- beverage
- functional
- methylated
- methylated catechin
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Abstract
Description
前記メチル化カテキンを、アレルギー性鼻炎抑制剤及び抗高脂血症剤として有効成分量含有する組成物。
本発明に係る機能性飲料は、下記に記載の所定の茶葉由来のメチル化カテキン成分をアレルギー性鼻炎抑制有効成分及び、中性脂肪低減剤とする機能性飲料である。この茶葉を湯で浸出して得た茶を飲むことにより、アレルギー性鼻炎を抑制し、かつ、中性脂肪を低減させることができる。
本発明に係る組成物は、所定の茶葉由来のメチル化カテキン成分をアレルギー性鼻炎抑制有効成分及び、中性脂肪低減剤とする組成物である。この組成物は、上記の茶葉からメチル化カテキンを従来公知の方法を用いて抽出して得られる。抽出際の温度は、溶媒の融点より高く、沸点より低い温度であれば、特に限定されるものではないが、水では10℃から100℃、エタノールおよびメタノールでは10℃から40℃が望ましい。抽出時間は10秒から24時間の範囲とするのが好ましい。
茶葉「べにふうき」は30倍量の純水を用いて、90℃で抽出を行って得た抽出液を、重曹などの水質調整剤及びビタミンCを添加混合した。殺菌し密封容器(本実施例では250ml紙パック)に窒素充填して試験飲料1とした。
比較例として、茶葉「やぶきた」をメチル化カテキン以外の成分含量が試験飲料1と同量となるように純水でメスアップし、重曹などの水質調整剤、ビタミンCを添加混合した。混合液を殺菌し密封容器中に窒素充填して試験飲料2とした。
比較例1同様の比較例として、「麦茶」をメチル化カテキン以外の成分含量が試験飲料1と同量となるように純水でメスアップし、重曹などの水質調整剤、ビタミンCを添加混合した。混合液を殺菌し密封容器中に窒素充填して試験飲料3とした。
実施例1及び比較例1、2で製造した被験飲料が、花粉症状を抑制するかについて試験を行った。試験は軽度の通年性鼻炎患者を一群20〜23名とし、それぞれの群に試験飲料1から3を12週間摂取させ、鼻炎の症状に及ぼす影響を調査した。試験は総合医科学研究所に委託し、試験のプロトコールは総合医科学研究所とアサヒ飲料株式会社、アサヒビール株式会社、独立行政法人農業・生物系特定産業技術研究機構の共同で設計した。
空腹時の中性脂肪値が100〜350mg/dLの健常成人10名を5名ずつ2群(ともに男性4名、女性1名)に分け、試験飲料1又は比較例2に係る試験飲料3を6週間摂取させた。各飲料は250mLの容器に入れ、1日に2本ずつ(500ml/日)の飲用とした。試験開始時と飲用終了時に一晩絶食後の中性脂肪値(平均±SD値)を測定した。このときの結果を表2及び図3に示す。これより、メチル化カテキンを含まない試験飲料3の摂取は血清中性脂肪値に影響しなかったのに対し、メチル化カテキンを含有する試験飲料1は中性脂肪値を有意に低下させた。
Claims (7)
- 前記機能性飲料は、茶葉を抽出して得られる飲料である請求項1に記載の機能性飲料。
- 前記機能性飲料100ml当たり、前記メチル化カテキンを1mgから30mg含有する請求項1又は2に記載の機能性飲料。
- 前記メチル化カテキンは、「べにふうき」、「べにふじ」、「べにほまれ」、「やえほ」、「するがわせ」、「ゆたかみどり」、「かなやみどり」、「おくむさし」、「青心大パン」、「青心烏龍」、「大葉烏龍」、「紅花」、「べにひかり」、「やまかい」、「やまみどり」、「からべに」、「香駿」、「そうふう」及び「おくみどり」、もしくはこれらの混合物の茶葉由来のものである請求項1から3いずれかに記載の機能性飲料。
- 前記機能性飲料は、アレルギー性鼻炎を抑制するために用いられる旨の表示及び/又は高脂血症、胆肝機能改善に有効であるために用いられる旨の表示を付したものである請求項1から4いずれかに記載の機能性飲料。
- 前記組成物は、飲食品、内服薬、塗布薬、鼻うがい剤、点鼻薬、化粧品又は、目の洗浄剤である請求項6に記載の組成物。
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JP2004030490 | 2004-02-06 | ||
JP2004030490 | 2004-02-06 | ||
PCT/JP2005/001700 WO2005074960A1 (ja) | 2004-02-06 | 2005-02-04 | 機能性飲料及び組成物 |
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JP2010247334A Division JP5825772B2 (ja) | 2004-02-06 | 2010-11-04 | 胆肝機能改善剤 |
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JP2005517749A Pending JPWO2005074960A1 (ja) | 2004-02-06 | 2005-02-04 | 機能性飲料及び組成物 |
JP2010247334A Active JP5825772B2 (ja) | 2004-02-06 | 2010-11-04 | 胆肝機能改善剤 |
JP2014013461A Pending JP2014114303A (ja) | 2004-02-06 | 2014-01-28 | 組成物 |
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JP2010247334A Active JP5825772B2 (ja) | 2004-02-06 | 2010-11-04 | 胆肝機能改善剤 |
JP2014013461A Pending JP2014114303A (ja) | 2004-02-06 | 2014-01-28 | 組成物 |
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US (1) | US20070128299A1 (ja) |
JP (3) | JPWO2005074960A1 (ja) |
KR (2) | KR100842634B1 (ja) |
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Cited By (1)
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JP2011503171A (ja) * | 2007-11-15 | 2011-01-27 | コーダリー | フラボノイドポリフェノール誘導体を含む組成物、並びに生体の疾患及び老化の制御におけるその適用 |
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JP2007077097A (ja) * | 2005-09-15 | 2007-03-29 | Tsumura & Co | 鼻用組成物 |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
JP4997523B2 (ja) * | 2006-01-13 | 2012-08-08 | 独立行政法人農業・食品産業技術総合研究機構 | 抗アレルギー剤及びこれを含有する飲食品、外用剤、化粧料 |
JP2007320864A (ja) * | 2006-05-30 | 2007-12-13 | Toshihiko Osawa | 非アルコール性脂肪肝炎予防・治療用組成物 |
JP2008094797A (ja) * | 2006-10-16 | 2008-04-24 | Morinaga & Co Ltd | 肥満抑制剤及び該肥満抑制剤を含む高脂肪含有飲食品 |
US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
JP5424533B2 (ja) * | 2007-01-23 | 2014-02-26 | アサヒ飲料株式会社 | 容器入り茶飲料群の製造方法 |
JP2008178319A (ja) * | 2007-01-23 | 2008-08-07 | Asahi Soft Drinks Co Ltd | 容器入り茶飲料群の製造方法 |
JP5128826B2 (ja) * | 2007-02-07 | 2013-01-23 | 独立行政法人農業・食品産業技術総合研究機構 | 新規なメチル化カテキン及びそれを含む組成 |
WO2009119113A1 (ja) * | 2008-03-28 | 2009-10-01 | 静岡県公立大学法人 | メチル化カテキン含有発酵茶飲料 |
JPWO2011042958A1 (ja) * | 2009-10-06 | 2013-02-28 | 森永製菓株式会社 | ポリフェノール類化合物の吸収促進剤及びその利用 |
JP2012031101A (ja) * | 2010-07-30 | 2012-02-16 | Kurume Univ | 非アルコール性脂肪性肝炎の改善用組成物 |
JP6105940B2 (ja) * | 2013-01-09 | 2017-03-29 | アサヒ飲料株式会社 | 酸性飲料及び耐熱性好酸性菌の増殖抑制方法 |
CN109221551A (zh) * | 2018-11-20 | 2019-01-18 | 广西中医药大学 | 一种降血脂抗氧化保健茶及其制备方法 |
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- 2005-02-04 KR KR1020087000171A patent/KR100842634B1/ko not_active IP Right Cessation
- 2005-02-04 US US10/588,428 patent/US20070128299A1/en not_active Abandoned
- 2005-02-04 CN CNA2005800038099A patent/CN1913911A/zh active Pending
- 2005-02-04 KR KR1020067017985A patent/KR100841834B1/ko not_active IP Right Cessation
- 2005-02-04 JP JP2005517749A patent/JPWO2005074960A1/ja active Pending
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Also Published As
Publication number | Publication date |
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WO2005074960A1 (ja) | 2005-08-18 |
KR20080014145A (ko) | 2008-02-13 |
KR20060115767A (ko) | 2006-11-09 |
JP2014114303A (ja) | 2014-06-26 |
US20070128299A1 (en) | 2007-06-07 |
KR100842634B1 (ko) | 2008-06-30 |
JP5825772B2 (ja) | 2015-12-02 |
KR100841834B1 (ko) | 2008-06-26 |
CN1913911A (zh) | 2007-02-14 |
JP2011021040A (ja) | 2011-02-03 |
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