JPS62189072A - Asceptic dissolving solution introducing device and dissolving solution introducing method using the same - Google Patents
Asceptic dissolving solution introducing device and dissolving solution introducing method using the sameInfo
- Publication number
- JPS62189072A JPS62189072A JP61031491A JP3149186A JPS62189072A JP S62189072 A JPS62189072 A JP S62189072A JP 61031491 A JP61031491 A JP 61031491A JP 3149186 A JP3149186 A JP 3149186A JP S62189072 A JPS62189072 A JP S62189072A
- Authority
- JP
- Japan
- Prior art keywords
- solution
- bottle
- introducer
- protector
- piercing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims description 9
- 239000000243 solution Substances 0.000 claims description 73
- 239000003814 drug Substances 0.000 claims description 43
- 239000007788 liquid Substances 0.000 claims description 28
- 229940079593 drug Drugs 0.000 claims description 27
- 230000001012 protector Effects 0.000 claims description 27
- 230000001954 sterilising effect Effects 0.000 claims description 21
- 238000004659 sterilization and disinfection Methods 0.000 claims description 10
- 239000008174 sterile solution Substances 0.000 claims description 8
- 238000010586 diagram Methods 0.000 description 7
- 230000009089 cytolysis Effects 0.000 description 5
- 238000011109 contamination Methods 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000006166 lysate Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000010836 blood and blood product Substances 0.000 description 1
- 229940125691 blood product Drugs 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000003978 infusion fluid Substances 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
〈産業上の利用分野〉
本発明は、無菌状態で一方の薬瓶より他方の薬瓶へ生理
食塩液や蒸留水、ブドウ糖液などの液体（以下、溶解液
という。）を導入するための無菌型溶解液導入器に関す
る。[Detailed Description of the Invention] <Industrial Application Field> The present invention provides a method for transferring a liquid (hereinafter referred to as a dissolving solution) such as physiological saline, distilled water, or glucose solution from one vial to another under aseptic conditions. ) relates to a sterile solution introducer for introducing a solution.
また本発明は、上記無菌型溶解液導入器を用いて行う新
しい溶解液導入方法に関する。The present invention also relates to a new method for introducing a solution using the above-mentioned sterile solution introducer.
尚、本考案に言う溶解液導入器とは、針部の軸方向に沿
って液体流通孔と気体流通孔とが並列に形成され、かつ
その両端に薬瓶のゴム栓に刺通するための刺通部を設け
た針、またはこの針を針部として有する、無菌状態で一
方の薬瓶より他方の薬瓶へ溶解液を導入するための器具
を言う。Note that the solution introducer referred to in the present invention has a liquid flow hole and a gas flow hole formed in parallel along the axial direction of the needle, and a hole at both ends for piercing the rubber stopper of a medicine bottle. A needle with a piercing part, or a device that has this needle as the needle part and is used to introduce a solution from one vial to another under sterile conditions.
〈従来の技術〉
抗生剤や血液製剤のように溶液の状態での保存が困難な
薬剤は、保存中の品質維持のために凍結乾燥され粉末に
されたものが市販されている。このような粉末状の医薬
品を患者に投与する場合には、一般にこれを溶解液に溶
解させて注射液や点滴液に調剤して用いており、従って
溶解液の入った瓶（以下、溶解銭瓶という。）から薬剤
の入った瓶（以下、薬剤板という。）に溶解液を無菌的
に導入するための操作が必要である。<Prior Art> Drugs that are difficult to store in a solution state, such as antibiotics and blood products, are commercially available as freeze-dried powders to maintain quality during storage. When administering such powdered pharmaceuticals to patients, they are generally dissolved in a solution and prepared as an injection or infusion solution. An operation is required to aseptically introduce the solution from the bottle containing the drug (hereinafter referred to as the drug plate).
このような溶解液導入操作においては、従来たとえば、
円板状の板とこの板の中央部を貫通してその両面に突設
した形の針部とからなる溶解液導入器や、この溶解液導
入器にさらに円筒状のケーシングを設け、このケーシン
グが前記円板状の板によって上下２つの部屋に分割され
るように形成された溶解液導入器（実開昭５７−１１７
３５１号公報）などが用いられている。In such a solution introduction operation, conventionally, for example,
A solution introducer is made up of a disk-shaped plate and a needle that penetrates through the center of the plate and protrudes from both sides, and the solution introducer is further provided with a cylindrical casing. A solution introducer is formed such that it is divided into two upper and lower chambers by the disc-shaped plate (Utility Model No. 57-117).
351 Publication) etc. are used.
またこれらの溶解液導入器を用いて溶解液の導入操作を
行う場合には、菌による汚染を防止するために針部に被
冠しであるプロテクタを取り外し、まず一方の刺通部を
溶解銭瓶のゴム栓に刺通し、次いで他方の刺通部を薬剤
板のゴム栓に刺通（第６図参照）、それから溶解銭瓶と
薬剤板の位置を逆転して溶解液が自身の重力１こよって
液体流通孔を通って薬剤板の中へ導入されるようにして
いた。In addition, when introducing the lysis solution using these lysis solution introducers, first remove the protector that covers the needle to prevent contamination with bacteria, and first insert one piercing part into the lysis solution. Pierce the rubber stopper of the bottle, then pierce the rubber stopper of the drug plate with the other piercing part (see Figure 6), then reverse the positions of the dissolving coin bottle and the drug plate so that the liquid dissolves under its own gravity. Therefore, the liquid was introduced into the drug plate through the liquid flow hole.
〈従来技術の問題点〉
しかしながら、従来の溶解液導入器は、刺通部を溶解銭
瓶に刺通した時に、一般に溶解銭瓶は僅かではあるが減
圧になっており、また液体流通孔も気体流通孔も両方の
刺通部に開口しているので、もう一方の刺通部から外気
が侵入し流通孔の開口部の高さが異っているため、一方
の刺通部を溶解銭瓶のゴム栓に刺通した後もう一方の刺
通部を薬剤板に刺通する場合、第６図に示すような液体
流通孔の開口部が薬剤板の内にあり気体流通孔の開口部
が薬剤板の外にあるような状態が生じ、一般に薬剤板は
減圧になっているので、気体流通孔から外気が進入し溶
解液瓶内および薬剤瓶内を汚染する虞れがあり問題であ
った。<Problems with the prior art> However, in conventional dissolution liquid introducers, when the piercing part is pierced into the dissolution coin bottle, the pressure in the dissolution coin bottle is generally reduced, albeit slightly, and there is no liquid flow hole. The gas circulation holes are also open in both piercings, so outside air enters through the other piercing and the heights of the openings of the circulation holes are different. When piercing the drug plate with the other piercing part after piercing the rubber stopper of the bottle, the opening of the liquid circulation hole is inside the drug plate and the opening of the gas circulation hole as shown in Figure 6. Since the drug plate is generally under reduced pressure, there is a risk that outside air may enter through the gas flow holes and contaminate the inside of the solution bottle and drug bottle, which is a problem. Ta.
〈問題点を解決するための手段〉
本願発明者は上記第１番目の問題点に鑑み鋭意検討を行
った結果、溶解液導入器の刺通部に除菌フィルタ付きの
プロテクタを被冠することに想到した。ところがこの刺
通部に除菌フィルタ付きのプロテクタを被冠した溶解液
導入器について実験を行ったところ、上記第２番目の問
題が生じることが分った。そこでさらに検討を行った結
果、液体流通孔と気体流通孔の開口部の高さをほぼ同じ
高さにすれば、より完全に溶解液導入操作中の外気の侵
入による汚染を無くすることができることに想到し、本
発明を完成した。<Means for Solving the Problems> As a result of intensive study in view of the first problem mentioned above, the inventor of the present application has decided to cover the piercing part of the solution introducer with a protector equipped with a sterilizing filter. I came up with this idea. However, when we conducted an experiment on a solution introducer whose piercing portion was covered with a protector with a sterilization filter, it was found that the second problem described above occurred. As a result of further investigation, we found that by making the openings of the liquid and gas flow holes almost the same height, it was possible to more completely eliminate contamination caused by outside air entering during the solution introduction operation. They came up with this idea and completed the present invention.
また本発明の溶解液導入器を用いて従来の溶解液導入方
法と同様に、先に溶解銭瓶のゴム栓に刺通し次いで薬剤
板のゴム栓に刺通する方式で溶解液導入操作を行った場
合、しばしば溶解液が流れなくなるという問題が生じた
ので、この点について鋭意検討を行ったところ、先に薬
剤板のゴム栓に刺通して薬剤板の内部の気圧を外気と同
じくした後溶解液瓶のゴム栓に刺通することにより、前
記問題点が解決されることを見出し、本願の第２番目の
発明を完成した。Furthermore, using the solution introducer of the present invention, the solution solution introduction operation was carried out by first piercing the rubber stopper of the solution bottle and then piercing the rubber stopper of the drug plate, in the same manner as the conventional solution introduction method. When using the drug plate, we often had the problem that the solution stopped flowing, so we conducted a thorough study on this issue and found that we first pierced the rubber stopper of the drug plate to equalize the pressure inside the drug plate with the outside air, and then removed the solution from the bottle. It was discovered that the above-mentioned problem could be solved by piercing the rubber stopper, and the second invention of the present application was completed.
すなわち本発明は、溶解液導入器の針部の２つの刺通部
に被冠したプロテクタのうち、少なが
くとも一方のプロテクタを除菌フィルタ付きプロテクタ
であることを特徴とする無菌型溶解液導入器であり、液
体流通孔と気体流通孔の開口部は、針部の軸方向に沿っ
てほぼ同じ高さに形成されたものが好ましい。That is, the present invention provides a sterile solution introduction method, characterized in that at least one of the protectors covered with the two piercing parts of the needle of the solution introduction device is a protector with a sterilization filter. Preferably, the openings of the liquid flow hole and the gas flow hole are formed at approximately the same height along the axial direction of the needle.
また本発明は、無菌型溶解液導入器の一方の刺通部に除
菌フィルタ付きプロテクタを被冠したまま、他方の刺通
部を薬剤板のゴム栓に刺通し、該薬剤瓶内の気圧を外気
と同じくした後、前記除菌フィルタ付きプロテクタを取
り外し、該プロテクタを取り外した刺通部を溶解銭瓶の
ゴム栓に刺通し、前記溶解銭瓶が無菌型溶解液導入器を
狭んで前記薬剤板の上に乗るように配置することを特徴
とする溶解液導入方法である。In addition, the present invention provides a method in which one piercing part of the sterile solution introducer is covered with a protector with a sterilizing filter, and the other piercing part is inserted into the rubber stopper of the medicine plate to reduce the air pressure inside the medicine bottle. After the air is exposed to the outside air, the protector with the sterilization filter is removed, and the piercing part from which the protector has been removed is pierced through the rubber stopper of the dissolving liquid bottle, and the dissolving liquid bottle narrows the sterile dissolving liquid introducer and the drug board is inserted. This is a method for introducing a solution, which is characterized by placing the solution on top of the solution.
く作用〉
本発明の溶解液導入器は、少なくとも一方の刺通部に除
菌フィルタ付きプロテクタを被冠しであるので、その一
方の刺通部に除菌フィルタ付きプロテクタを被冠したま
まもう一方の刺通部を薬剤瓶に刺通した場合、外気は除
菌フィルタで浄化された後気体流通孔を通って薬剤瓶内
に導入されるので、薬剤瓶内が汚染されることはない。Effect> Since the solution introducer of the present invention has at least one piercing portion covered with a protector with a sterilizing filter, it is possible to use the solution introducer with the protector equipped with a sterilizing filter covering one of the piercing portions. When one piercing part is inserted into a medicine bottle, the outside air is purified by the sterilization filter and then introduced into the medicine bottle through the gas flow hole, so that the inside of the medicine bottle is not contaminated.
また、本発明の溶解液導入器は、゛針部の軸方向に沿っ
て形成された液体流通孔と気体流通孔の開口部の高さが
ほぼ等しいので、もう一方の刺通部を溶解液瓶に刺通し
た場合、液体流通孔と気体流通孔の開口部はほぼ同時°
に溶解液瓶内の雰囲気に露出されることになり、従って
汚染した外気が気体流通孔を通って薬剤瓶内に入り、次
いで液体流通孔を通って溶解液瓶内に流入するというよ
うな第６図に示すのと同様の現象を生ずることはなく、
瓶内が汚染されることもない０
また本発明の溶解液導入方法は、まず薬剤瓶内の気圧を
外部の気圧と等しくした・後に薬剤瓶内部と溶解液瓶内
部とを連通しているので、溶解液導入器を介して連通さ
れた薬剤瓶内の気圧は僅かではあるが溶解液瓶内の気圧
より大きくなり、従って溶解液導入器を介して薬剤瓶が
下に溶解液瓶が土になるように配置した場合、気体は高
圧側から低圧側に移動するので、薬剤瓶内の空気が気体
流通孔を通ってスムーズに溶解液瓶内に流入することが
でき、従って溶解液ももう一方の液体流通孔を通ってス
ムーズに薬剤瓶内に導入される。In addition, in the solution introducer of the present invention, since the openings of the liquid flow hole and the gas flow hole formed along the axial direction of the needle portion are approximately equal in height, the other piercing portion is connected to the solution solution. When a bottle is pierced, the openings of the liquid flow hole and the gas flow hole are almost at the same time.
exposure to the atmosphere within the lysate bottle, such that contaminated outside air enters the drug bottle through the gas flow hole and then flows into the lysate bottle through the liquid flow hole. The same phenomenon as shown in Figure 6 does not occur,
The inside of the bottle is not contaminated. Furthermore, the method of introducing the solution solution of the present invention first equalizes the pressure inside the drug bottle with the outside pressure, and then communicates the inside of the drug bottle with the inside of the solution bottle. , the air pressure inside the drug bottle communicated through the solution introducer is slightly larger than the pressure inside the solution bottle, so that the drug bottle is lowered through the solution introducer and the solution bottle is lowered into the soil. When arranged so that the gas moves from the high-pressure side to the low-pressure side, the air in the medicine bottle can smoothly flow into the solution bottle through the gas flow hole, and the solution also flows from the other side. The liquid is smoothly introduced into the drug bottle through the liquid flow hole.
〈実施例〉 次に図面を用いて本発明の実施例について説明する。<Example> Next, embodiments of the present invention will be described using the drawings.
第１図および第２図はそれぞれ本発明の溶解液導入器の
一実施例を示す正面図および平面図（プロテクタは省略
しである）、第３図は第２図のＸ−Ｘ線断面図、第４図
は本発明の溶解液導入器を薬液瓶に連通し外気を導入す
る操作の説明図、第５図は本発明の溶解液導入器を用い
た溶解液導入操作の説明図であり、第６図は従来の溶解
液導入器を用いた溶解液導入操作の問題点説明図である
。1 and 2 are a front view and a plan view, respectively, showing an embodiment of the solution introducer of the present invention (the protector is omitted), and FIG. 3 is a sectional view taken along the line X-X of FIG. 2. , FIG. 4 is an explanatory diagram of the operation of connecting the solution introducer of the present invention to a drug solution bottle and introducing outside air, and FIG. 5 is an explanatory diagram of the operation of introducing the solution using the solution introducer of the present invention. , FIG. 6 is a diagram illustrating problems in the solution introduction operation using a conventional solution introduction device.
第１〜３図に示されるように本発明の溶解液導入器は、
両端が開いた円筒状ケーシング（１）の内部に、このケ
ーシング（１）と共に一体に成形された分離板（２）と
、この分離板（２）を貫通する針部（５）および、この
針部（５）の刺通部（５ａ）および（５ｂ）に被冠した
プロテクタ（省略しである）とからなり、針部（５）に
は液体流通孔（３）と気体流通孔（４）とが針部（５）
の軸方向に沿って平行に形成されており、プロテクタの
少なくとも一方は除菌フィルタ付きプロテクタである。As shown in FIGS. 1 to 3, the solution introducer of the present invention is
Inside a cylindrical casing (1) with both ends open, there is a separation plate (2) integrally formed with the casing (1), a needle part (5) passing through the separation plate (2), and the needle. It consists of a protector (omitted) that covers the piercing parts (5a) and (5b) of the part (5), and the needle part (5) has a liquid circulation hole (3) and a gas circulation hole (4). Toga needle part (5)
are formed parallel to the axial direction, and at least one of the protectors is a protector with a sterilization filter.
そして前記液体流通孔（３）と気体流通孔（４）の開口
部（３ａと４ａ１３ｂと４ｂ）は、第６図のように気体
流通孔の開口部（４ａ）が薬剤瓶（１１）の外側にあり
液体流通孔の開口部（３ａ）が薬剤瓶の内側にあるよう
なことの起らないように、近接した高さに形成されてお
り、好ましくは、はぼ同じ高さに形成されている。The openings (3a, 4a, 13b and 4b) of the liquid distribution hole (3) and the gas distribution hole (4) are such that the opening (4a) of the gas distribution hole is located outside the medicine bottle (11) as shown in FIG. The openings (3a) of the liquid flow holes are formed at close heights, and preferably at approximately the same height, to prevent the openings (3a) of the liquid flow holes from being located inside the medicine bottle. There is.
除菌フィルタ付きプロテクタは、通常使用されている形
状のプロテクタの閉鎖端を取り外してそこに除菌フィル
タを詰めたもので良く、円４図参照）。A protector with a sterilizing filter may be a protector with a normally used shape, with the closed end removed and a sterilizing filter filled therein (see diagram circle 4).
図中（６）は転がり防止用載置面であり、環状の小突起
（８１）および（８２）は口部の小さな薬瓶を使用した
場合に、刺通部（５ａ）および／または（５ｂ）を薬瓶
のゴム栓に真直ぐに刺通できるようにするもので、薬瓶
の口部が丁度嵌め込まれる大きさに形成されている。In the figure, (6) is the mounting surface for preventing rolling, and the annular small protrusions (81) and (82) are the piercing parts (5a) and/or (5b) when using a medicine bottle with a small mouth. ) can be inserted straight through the rubber stopper of a medicine bottle, and is sized to fit the mouth of the medicine bottle.
本発明の溶解液導入器を使用した溶解液導入操作につい
ては、第４図に示すように、まず溶解液導入器のプロテ
クタ（省略しである）を取り外し、除菌フィルタ付きプ
ロテクタ（９）を被冠したまま、刺通部（５ｂ）を薬剤
瓶（１１）のゴム栓（１２）に刺通し、液体流通孔（３
）および気体流通孔（４）から薬剤瓶（１１）内に除菌
フィルタ付きプロテクタ（９）で−過された清浄な外気
を導入して、瓶（１１）内の気圧を瓶（１１）外の気圧
と等しくする。Regarding the lysis solution introduction operation using the lysis solution introducer of the present invention, as shown in FIG. While wearing the crown, pierce the piercing part (5b) into the rubber stopper (12) of the drug bottle (11) and open the liquid flow hole (3).
) and the gas flow hole (4) into the drug bottle (11) through the protector (9) with a sterilizing filter, and introduce clean outside air that has been passed through the protector (9) with a sterilizing filter to reduce the air pressure inside the bottle (11) to the outside of the bottle (11). equal to the atmospheric pressure.
次にもう一方の刺通部（５ａ）を第５図に示すように溶
解液瓶（１３）のゴム栓（１４）に刺通すれば、溶解液
（１５）は自身の重力によって液体流通孔（３）を通っ
て薬剤瓶（１１）に導入される。Next, if the other piercing part (5a) is pierced through the rubber stopper (14) of the solution bottle (13) as shown in Figure 5, the solution (15) will flow through the liquid distribution hole by its own gravity. (3) and is introduced into the medicine bottle (11).
尚刺通部（５ａ）の溶解液瓶（１３）のゴム栓（１４）
への刺通は、瓶（１３）を持ってそのゴム栓（１４）を
刺通部（５ａ）に押し当てて行っても良いし、第６図の
ように溶解液瓶（１３）を下に置いて上から刺通部（５
ａ）を瓶（１３）のゴム栓（１４）に押し当てて行って
も良い。In addition, the rubber stopper (14) of the solution bottle (13) in the piercing part (5a)
To pierce the bottle, you can hold the bottle (13) and press its rubber stopper (14) against the piercing part (5a), or you can lower the solution bottle (13) as shown in Figure 6. from above and insert the piercing part (5
You may also press a) onto the rubber stopper (14) of the bottle (13).
く効果〉
以上述べてきたことから明らかなように、本発明の溶解
液導入器は次のような利点を有する。Effects> As is clear from what has been described above, the solution introducer of the present invention has the following advantages.
（１） 溶解液導入器の針部の２つの刺通部のうち少
なくとも一方の刺通部に除菌フィルタ付きプロテクタを
被冠しであるので、この刺通部に除菌フィルタ付きプロ
テクタを被冠したまま他方の刺通部を薬瓶のゴム栓に刺
通した場合、液体流通孔や気体流通孔から外部の汚染さ
れた空気がそのまま瓶内に導入されることがなく、除菌
フィルタで濾過された清浄な空気が導入されるので、瓶
内が外部からの空気によって汚染されることがない。(1) At least one of the two piercing parts of the needle of the solution introducer is covered with a protector with a sterilizing filter, so this piercing part is covered with a protector with a sterilizing filter. If you pierce the rubber stopper of a medicine bottle with the other piercing part while the crown is still in place, contaminated air from outside will not be directly introduced into the bottle through the liquid circulation hole or gas circulation hole, and the sterilization filter will prevent Since filtered clean air is introduced, the inside of the bottle is not contaminated by air from outside.
（２） 液体流通孔と気体流通孔の開口部の高さが針
部の軸方向に沿ってほぼ等しく形成されているので、第
６図に示すような気体流通孔を通って外部の汚染された
空気が侵入するというようなことが起らず、従って瓶内
が外気で汚染されることがない。(2) Since the heights of the openings of the liquid distribution hole and the gas distribution hole are approximately equal along the axial direction of the needle, contamination from the outside does not pass through the gas distribution hole as shown in Figure 6. This prevents air from entering the bottle, and therefore the inside of the bottle is not contaminated with outside air.
第１図および第２図はそれぞれ本発明の溶解液導入器の
一実施例を示す正面図および平面図であり（プロテクタ
は省略しである）、第３図は第２図のＸ−Ｘ線断面図で
ある。また第４図は本発明の溶解液導入器を薬剤瓶に連
通し外気を導入する操作の説明図、第５図は本発明の溶
解液導入器を用いた溶解液導入操作の説明図である。
また第６図は従来の溶解液導入器を用いた溶解液導入操
作の問題点説明図である。
く主な符号の説明〉
３：液体流通孔 ４：気体流通孔３ａ、 ３ｂ１
４ａ、 ４ｂ ：開口部５：針部 ５ａ、
５ｂ ：刺通部９：除菌フィルタ付きプロテクタ
ｌＯ：除菌フィルタ1 and 2 are a front view and a plan view, respectively, showing an embodiment of the solution introducer of the present invention (the protector is omitted), and FIG. FIG. FIG. 4 is an explanatory diagram of the operation of communicating the solution introducer of the present invention to a drug bottle and introducing outside air, and FIG. 5 is an explanatory diagram of the operation of introducing the solution using the solution introducer of the present invention. . Further, FIG. 6 is a diagram illustrating problems in the operation of introducing a solution using a conventional solution introducer. Explanation of main symbols> 3: Liquid flow holes 4: Gas flow holes 3a, 3b1
4a, 4b: Opening 5: Needle 5a,
5b: Penetration part 9: Protector with sterilization filter lO: sterilization filter
Claims (1)
テクタのうち、少なくとも一方のプロテクタが除菌フィ
ルタ付きプロテクタであることを特徴とする無菌型溶解
液導入器。 ２）前記針部の軸方向に沿って形成された液体流通孔と
気体流通孔の開口部の高さがほぼ同じ高さである特許請
求の範囲第１項記載の無菌型溶解液導入器。 ３）無菌型溶解液導入器の一方の刺通部に除菌フィルタ
付きプロテクタを被冠したまま、他方の刺通部を薬剤瓶
のゴム栓に刺通し、該薬剤瓶内の気圧を外気と同じくし
た後、前記除菌フィルタ付きプロテクタを取り外し、該
プロテクタを取り外した刺通部を溶解液瓶のゴム栓に刺
通し、前記溶解液瓶が無菌型溶解液導入器を狭んで前記
薬剤瓶の上に乗るように配置することを特徴とする溶解
液導入方法。[Scope of Claims] 1) A sterile solution solution, characterized in that at least one of the protectors covering the two piercing parts of the needle of the solution introducer is a protector with a sterilization filter. Introducer. 2) The sterile solution introducer according to claim 1, wherein the heights of the openings of the liquid circulation hole and the gas circulation hole formed along the axial direction of the needle portion are approximately the same height. 3) While one piercing part of the sterile solution introducer is covered with a protector with a sterilization filter, the other piercing part is inserted into the rubber stopper of the drug bottle, and the pressure inside the drug bottle is adjusted to the same level as the outside air. After that, the protector with the sterilizing filter is removed, and the piercing part from which the protector has been removed is pierced through the rubber stopper of the solution bottle, and the solution bottle is inserted into the sterile solution introducer and placed on top of the medicine bottle. A method for introducing a solution, which is characterized by placing the solution in such a way that it rides on the surface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61031491A JPH06145B2 (en) | 1986-02-15 | 1986-02-15 | Sterile dissolution solution introducing device and dissolution solution introducing method using the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61031491A JPH06145B2 (en) | 1986-02-15 | 1986-02-15 | Sterile dissolution solution introducing device and dissolution solution introducing method using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62189072A true JPS62189072A (en) | 1987-08-18 |
| JPH06145B2 JPH06145B2 (en) | 1994-01-05 |
Family
ID=12332726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61031491A Expired - Fee Related JPH06145B2 (en) | 1986-02-15 | 1986-02-15 | Sterile dissolution solution introducing device and dissolution solution introducing method using the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH06145B2 (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0259196U (en) * | 1988-10-24 | 1990-04-27 | ||
| JPH0852196A (en) * | 1994-08-09 | 1996-02-27 | Material Eng Tech Lab Inc | Transfusion container having connecting port for medicine |
| WO2001091694A1 (en) * | 2000-06-01 | 2001-12-06 | Mitsubishi Pharma Corporaion | Plug-equipped liquid medicine container |
| WO2010061743A1 (en) * | 2008-11-25 | 2010-06-03 | 株式会社ジェイ・エム・エス | Connector |
| JP2010528808A (en) * | 2007-06-13 | 2010-08-26 | カルメル プハルマ アクチボラゲット | Mounting tool for use with medical devices |
| JP2011224223A (en) * | 2010-04-21 | 2011-11-10 | Terumo Corp | Medical instrument connector and drug administration instrument |
| US8556879B2 (en) | 2008-11-25 | 2013-10-15 | Jms Co., Ltd. | Connector |
| JP2014131763A (en) * | 2014-03-13 | 2014-07-17 | Terumo Corp | Medical device connector and medicament administration device |
| US10420927B2 (en) | 2015-12-04 | 2019-09-24 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| USD874644S1 (en) | 2016-07-19 | 2020-02-04 | Icu Medical, Inc. | Medical fluid transfer system |
| US11007119B2 (en) | 2009-07-29 | 2021-05-18 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11020541B2 (en) | 2016-07-25 | 2021-06-01 | Icu Medical, Inc. | Systems, methods, and components for trapping air bubbles in medical fluid transfer modules and systems |
| US11439570B2 (en) | 2011-12-22 | 2022-09-13 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11541171B2 (en) | 2013-11-25 | 2023-01-03 | Icu Medical, Inc. | Methods and systems for filling IV bags with therapeutic fluid |
| US11590057B2 (en) | 2020-04-03 | 2023-02-28 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5757848U (en) * | 1980-09-19 | 1982-04-05 | ||
| JPS59500600A (en) * | 1982-04-06 | 1984-04-12 | バクスタ−、インターナショナル、インコ−ポレイテッド | Medical liquid drug component mixing device with sterile coupling |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53114021A (en) * | 1977-03-16 | 1978-10-05 | Hitachi Ltd | Noise-proof electric machinery |
-
1986
- 1986-02-15 JP JP61031491A patent/JPH06145B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5757848U (en) * | 1980-09-19 | 1982-04-05 | ||
| JPS59500600A (en) * | 1982-04-06 | 1984-04-12 | バクスタ−、インターナショナル、インコ−ポレイテッド | Medical liquid drug component mixing device with sterile coupling |
Cited By (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0259196U (en) * | 1988-10-24 | 1990-04-27 | ||
| JPH0852196A (en) * | 1994-08-09 | 1996-02-27 | Material Eng Tech Lab Inc | Transfusion container having connecting port for medicine |
| WO2001091694A1 (en) * | 2000-06-01 | 2001-12-06 | Mitsubishi Pharma Corporaion | Plug-equipped liquid medicine container |
| JP2010528808A (en) * | 2007-06-13 | 2010-08-26 | カルメル プハルマ アクチボラゲット | Mounting tool for use with medical devices |
| JP5557040B2 (en) * | 2008-11-25 | 2014-07-23 | 株式会社ジェイ・エム・エス | connector |
| WO2010061743A1 (en) * | 2008-11-25 | 2010-06-03 | 株式会社ジェイ・エム・エス | Connector |
| JPWO2010061743A1 (en) * | 2008-11-25 | 2012-04-26 | 株式会社ジェイ・エム・エス | connector |
| US8506548B2 (en) | 2008-11-25 | 2013-08-13 | Jms Co., Ltd. | Connector |
| US8556879B2 (en) | 2008-11-25 | 2013-10-15 | Jms Co., Ltd. | Connector |
| US11007119B2 (en) | 2009-07-29 | 2021-05-18 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11806308B2 (en) | 2009-07-29 | 2023-11-07 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| JP2011224223A (en) * | 2010-04-21 | 2011-11-10 | Terumo Corp | Medical instrument connector and drug administration instrument |
| US11439571B2 (en) | 2011-12-22 | 2022-09-13 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11439570B2 (en) | 2011-12-22 | 2022-09-13 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11541171B2 (en) | 2013-11-25 | 2023-01-03 | Icu Medical, Inc. | Methods and systems for filling IV bags with therapeutic fluid |
| JP2014131763A (en) * | 2014-03-13 | 2014-07-17 | Terumo Corp | Medical device connector and medicament administration device |
| USD948044S1 (en) | 2015-12-04 | 2022-04-05 | Icu Medical, Inc. | Fluid transfer device |
| US11135416B2 (en) | 2015-12-04 | 2021-10-05 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| US10420927B2 (en) | 2015-12-04 | 2019-09-24 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| US11865295B2 (en) | 2015-12-04 | 2024-01-09 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| USD1018849S1 (en) | 2015-12-04 | 2024-03-19 | Icu Medical, Inc. | Fluid transfer device |
| USD943732S1 (en) | 2016-07-19 | 2022-02-15 | Icu Medical, Inc. | Medical fluid transfer system |
| USD905228S1 (en) | 2016-07-19 | 2020-12-15 | Icu Medical, Inc. | Medical fluid transfer system |
| USD874644S1 (en) | 2016-07-19 | 2020-02-04 | Icu Medical, Inc. | Medical fluid transfer system |
| US11020541B2 (en) | 2016-07-25 | 2021-06-01 | Icu Medical, Inc. | Systems, methods, and components for trapping air bubbles in medical fluid transfer modules and systems |
| US11583637B2 (en) | 2016-07-25 | 2023-02-21 | Icu Medical, Inc. | Systems, methods, and components for trapping air bubbles in medical fluid transfer modules and systems |
| US11951293B2 (en) | 2016-07-25 | 2024-04-09 | Icu Medical, Inc. | Systems, methods, and components for trapping air bubbles in medical fluid transfer modules and systems |
| US11590057B2 (en) | 2020-04-03 | 2023-02-28 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06145B2 (en) | 1994-01-05 |
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