JPS61500059A - 経皮接近を利用する高容量の脈管内血液ポンプ - Google Patents
経皮接近を利用する高容量の脈管内血液ポンプInfo
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- JPS61500059A JPS61500059A JP59503865A JP50386584A JPS61500059A JP S61500059 A JPS61500059 A JP S61500059A JP 59503865 A JP59503865 A JP 59503865A JP 50386584 A JP50386584 A JP 50386584A JP S61500059 A JPS61500059 A JP S61500059A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/827—Sealings between moving parts
- A61M60/829—Sealings between moving parts having a purge fluid supply
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/405—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/804—Impellers
- A61M60/806—Vanes or blades
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/818—Bearings
- A61M60/825—Contact bearings, e.g. ball-and-cup or pivot bearings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/871—Energy supply devices; Converters therefor
- A61M60/88—Percutaneous cables
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
- A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
- A61M60/414—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/818—Bearings
- A61M60/824—Hydrodynamic or fluid film bearings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/03—Heart-lung
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S415/00—Rotary kinetic fluid motors or pumps
- Y10S415/90—Rotary blood pump
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるため要約のデータは記録されません。
Description
【発明の詳細な説明】
経皮接近を利用する高容量の脈管内面液ポンプ技 術 分 野
本発明は血液ポンプ、特に大手術をすることなく脈管系内に経皮挿入して右また
は左心室の血液流動を十分にすることにより一時的に心臓機能を助けることので
きる小形血液ポンプに関するものである。
背 景 技 術
医者は心臓性シヨ・ンクの症例(すなわち、心臓はまだ機能しているも、患者を
生存させるのには十分な血液を送り出していない状8)に頻繁に直面する。この
ような状態の緊急処置には、患者を生存させるのに十分な程度に血流を維持する
何等かの形態の心臓機能救援手段がしばしば必要とされるも、他の手段を着手し
て心臓そのものを一層正常に機能すべく回復させる必要がある。
現在斯種の心臓機能救援手段に対する有効な方法は、大手術をして脈管系に接続
するポンプ装置によるものか、または適当な動脈内に挿入するバルーンカテーテ
ルによるものだけである。遺憾ながら、大手術は心臓性ショックの患者には時間
がかかり過ぎ、また危険を伴ない、しかもバルーンカテーテルは心臓からの血液
の送り出しを十分に向上させることができない。
非開胸脈管接近法を用いて血液の左側循環を支えることが提案されている。斯種
の方式では2つの動脈部位を同時に用いて血液を心臓から動脈系へと送り出すよ
うにしている。しかし、この技法には長くて孔の小さいカニユーレを使用する必
要があり、斯様なカニユーレでは圧力降下が大きくなる。カニユーレの導管が負
圧を受けると、空気塞栓症および重い合併症をまねくことになる。さらに、ポン
プ′を心臓、に接近さiるためには鎖骨下動脈を用いてポンプを挿入する必要が
ある。斯かる動脈への外科的接近法は大腿部動脈への場合よりもずっと困難であ
る。
右心機能を支えるため外部ポンプを用いるには、2つの静脈部位にて同時に接近
させる必要がある。この場合にはポンプ出力を長くて孔の小さいカニユーレによ
って肺動脈に戻す必要がある。この場合にも負圧による圧力降下が大きくて同様
な合併症や、場合によっては空気塞栓症が生じたりする。従って従来技術では心
臓の血流を迅速に十分なものとして、重症患者を助けることのできる簡単な構成
で、危険度の低い血液循環救援装置を提供することはできなかった。
発明の開示
本発明は、末梢静脈または動脈系のいずれかを介して右または左心室に直接接近
させて、血液循環を助けるのに十分な程度に小さい軸方向タイプを可とする高速
小形血液ポンプを提供することにより従来の諸問題を解決することにある。斯か
る装置は末梢経皮挿入するものであり、しかもその装置の流量は毎分当り3〜4
fL程度とすることができる。
右心室の機能を支えるにはポンプを三尖弁および肺動脈弁を経て肺動脈内へと前
向きに挿入する。斯様な処置は末梢血管から大腿部静脈、外頚静脈または頭部付
近の静脈を経て行うことができる。
左心室の機能を支えるにはポンプを大動脈弁を経て左心室へと逆向きに挿入して
行う。これは鎖骨下動脈または大腿部動脈のいずれかから行うことができる。
ポンプを周囲から接近させるのが困難な場合には、少し胸壁切開して脈管接近さ
せることによりポンプを心室先端部へと導入させることができる。
本発明によるポンプは全身の循環通路の部位に小直径のカニユーレを経て延在さ
せる可撓性ケーブルまたは水圧管路を介して人体の外側における小形動カニニッ
トによって駆動させる。
必要な血液を放出させるためには、本発明のポンプを10,000〜20.OO
Orpmの軸速度で作動させる必要がある。このような高速回転ポンプは以前は
血液ポンプの用途には適さないと考えられていた。その理由は、羽根車チャンバ
の固定壁部付近を通る羽根車の羽根の先端部がゼブリ溶血を生ぜしめる程に大き
い剪断力を生するであろうと一般に考えられていたからである。本発明は、羽根
の先端部の線速度がポンプの直径に依存し、このために本発明によるような小形
ポンプでは斯かる線速度が十分に小さくなり、ポンプ動作に必要な速度でもさほ
ど溶血を生じないと云う認識に基づいて成したものである。
本発明によるポンプでは、その回転部と固定部との間にパージシールを用いるこ
とによって血栓形成を回避させる。さらに、軸受潤滑剤として作用し得るエタノ
ールまたは同様な静菌剤をパージ流体として用いることによって静菌効果を達成
することもできる。
従って、本発明の目的は心臓の機能を助ける目的のために大手術をすることなく
脈管系を経て心臓に迅速に接近させることができ、しかも患者への危険度が低い
高容量小形血液ポンプを提供することにある。
本発明の他の目的は血液凝固を阻止する上述したタイプのポンプを提供すること
にある。
図面の簡単な説明
第1a図は心臓機能を助ける目的のための本発明ポンプの好適な位置付けの様子
を示しているほぼ大動脈平面での人間の心臓の切開図;
第1b図は大腿部動脈を経て本発明ポンプの挿入の様子を示している人間の概略
図;
第2図は本発明ポンプの一部を概略的に示す軸方向断面図:
第3a図および第3b図は第2図のポンプの3a−3aおよび3b−3b線に沿
う断片的横断面図;第4図は第2図のポンプの4−4線に沿う断片的断面図であ
る。
発明を実施するための最良の形態
本発明の脈管内面液ポンプ10は、適当に短くて、可牒性の送り込みカニユーレ
14を逆向きに挿入することによって大動脈弁15を経て心臓11の左心室12
(第1a図)に接近させることができる。カニユーレ14は、それを有利に挿入
させることのできる大腿部18における大腿部動脈17(第1b図)から大動脈
16を経て案内させる。ポンプ10の作動時には血液が左心室12からカニユー
レ14の入口素子19およびカニユーレ14の内部を経てポンプ10内に矢印(
第1a図)の方向に送り出される。ポンプ10の出口には送り出された血液が出
口素子20を経て大動脈16へと放出される。
本発明ポンプを、ここでは大腿部動脈を経て逆向きに挿入して左心室の機能を助
けることについて述べたが、本発明ポンプはさほど変更しなくても所要に応じ他
の挿入技法により上述したようにして左心室または右心室の機能を助けるように
使用することもできることは明らかである。
ポンプ10は大腿部動脈17および大動脈16内に入れたカテーテル26を経て
延在させる可撓性の軸24によって駆動させるのが好適である。カテーテル26
は下記に述べるような目的および機能をするノぐ−ジ流体用の導管としても作用
する。ポンプlOに動力を与えるのに11軸24の代りにカテーテル26を用い
る水圧系を同等に用し)ることかできる。
第1a図および第1b図の配置では、患者の身体の外側に置いた適当な支持ユニ
ット28によって軸24に対する駆動力を与えると共に、カテーテル2Bを経て
ポンプ10にパージ流体も与える。カテーテル26の直径は十分小さくして、そ
れを動脈に挿入する際に血液がそのまわりを比較的支障なく流れるようにする。
次に第2図に転するに、ポンプ10はそのポンプ本体に沿ってほぼ円筒形をして
いるハウジング30を有している。入口素子18および出口素子20にはテーパ
ーを付けて、患者の脈管系を経てのポンプlOの挿入および引出しをし易くする
。支持支柱38(これは固定子羽根としても作用する)はハウジング30を固定
子支持軸受40およびチューブ取付は円錐部42に接続する。
円筒状固定子ハブ40はケーブル24によって駆動されるような回転運動に対し
て回転子44を支持する。回転子44の軸方向運動は軸受フランジ46によって
防止される。回転子44は一連の回転子羽根を支承し、これらの羽根の湾曲断面
(第4図に明示しである)は固定子羽根36のそれに似ている。しかし、各羽根
リングにおける回転子羽根の数は、第3図に明示したように、各すングにおける
固定子羽根の数とは相違さセる(例えば、回転子羽根はリング当り7個とし、固
定子羽根はリング当り11個とすることができる)。
ジャーナル軸受41はカテーテル2Gを経てポンプ10内に圧力下で導入させる
パージ流体を絶えず流すことによって滑らかにする。パージ流体50はフェース
シール52を経て流れ、最終的には界面56の個所にて血流54に放出される。
1883年9月28日出願の凝血抑制血液ポンプなる名称の同時係属米国特許出
願第537,243号に記載したように、ポンプ10内での血栓形成は、環状界
面56に沿ってパージ流体を十分に流出し続けて界面56の個所にて血液′要素
が回転子および固定子表面に接触しないようにすることによって防止される。
本発明のポンプは極めて小さくする必要がある。その外径は理想的には7〜9菖
菖以下とすべきである。はぼ4文/分の流量で必要な血液を流すためには、本発
明のポンプをほぼ10,000〜20.00Orpmの速度で作動させる必要が
ある。ポンプの作動時には、羽根36および48の先端部が絶えず回転子44お
よびハウジング30にそれぞれ接近して動く第2図の58および60の個所にお
ける羽根先の環状領域にて剪断作用が生ずる。しかし、ポンプの寸法が極めて小
さいため、領域58にて生ずる最悪のケースでのハウジング30に対する羽根4
8の先端部の相対運動は511I/秒以下に留まる。この相対速度は、羽根先端
部の適当な隙間(はぼ0.1mm )と相俟ってスペース58内の剪断力を十分
低いレベルに維持して、不当な溶血を生ぜしめなくするに十分な低い値である。
スペース60の方がスペース58よりもポンプ10の軸線に近いために、固定子
羽根36と回転子44との間の相対速度が小さくなるので、スペース6o内での
赤血球細胞膜の破壊は一層少なくなる。
本発明は手術することなく、しかも患者への危険も最小にして迅速にあてがうこ
とができ、かつ取外すことのできる有効な脈管心臓機能救援方法および装置を国
際調査報告
Claims (6)
- 1.a)脈管系内に、該脈管系によって完全に収容されるべく連続作動するポン プ手段を挿入する工程;および b)前記脈管系を経て血流を生ぜしめるために前記ポンプ手段を作動させる工程 ; を具えることを特徴とする大手術をすることなく心臓機能を大いに助ける方法。
- 2.a)両端部が開放しており、人間の血管に通すことのできる形状および大き さを有している細長形のハウジングと; b)前記ハウジングを経て長手方向に血液を送り出す前記ハウジング内の回転ポ ンプ手段と;c)前記ハウジングから延在し、かつ前記血管内に該血管を閉塞す ることなく入れられる導管手段と; d)前記ポンプ手段に動力を供給するための動力手段と; e)前記動力手段から前記ポンプ手段に駆動力を伝達するための前記導管内の駆 動手段; とを具えることを特徴とする脈管内血液ポンプ。
- 3.前記駆動手段が前記導管手段を経て延在する可撓性のケーブルを含むように したことを特徴とする請求の範囲第2項に記載のポンプ。
- 4.前記回転ポンプ手段が、固定子および回転子手段と、これらの固定子および 回転子手段を相対的に回転させるように取付ける軸受手段とを具え;前記軸受手 段をパージシールし;かつパージ流体を前記導管手段を経て前記軸受手段に十分 な速度で放出させて、血液要素が前記パージシールに入らないようにしたことを 特徴とする請求の範囲第2項に記載のポンプ。
- 5.前記回転ポンプ手段をほぼ10,000〜20,000rpmの回転速度で 作動する軸流ポンプとしたことを特徴とする請求の範囲第2項に記載のポンプ。
- 6.前記回転ポンプ手段の血流速度を毎分当りほぼ4リットルとしたことを特徴 とする請求の範囲第2項に記載のポンプ。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/537,244 US4625712A (en) | 1983-09-28 | 1983-09-28 | High-capacity intravascular blood pump utilizing percutaneous access |
US537244 | 1983-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61500059A true JPS61500059A (ja) | 1986-01-16 |
JPH0531423B2 JPH0531423B2 (ja) | 1993-05-12 |
Family
ID=24141837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59503865A Granted JPS61500059A (ja) | 1983-09-28 | 1984-09-28 | 経皮接近を利用する高容量の脈管内血液ポンプ |
Country Status (7)
Country | Link |
---|---|
US (1) | US4625712A (ja) |
EP (1) | EP0157871B1 (ja) |
JP (1) | JPS61500059A (ja) |
BR (1) | BR8407086A (ja) |
CA (1) | CA1240802A (ja) |
DE (1) | DE3482656D1 (ja) |
WO (1) | WO1985001432A1 (ja) |
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JP2000511455A (ja) * | 1997-04-02 | 2000-09-05 | インペラ カーディオテヒニック ゲゼルシャフト ミット ベシュレンクター ハフツング | 心臓内ポンプ装置 |
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JP2008121687A (ja) * | 2007-11-26 | 2008-05-29 | Mitsubishi Heavy Ind Ltd | 人工心臓ポンプ |
JP4523962B2 (ja) * | 2007-11-26 | 2010-08-11 | 三菱重工業株式会社 | 人工心臓ポンプ |
JP4611365B2 (ja) * | 2007-11-26 | 2011-01-12 | 三菱重工業株式会社 | 人工心臓ポンプ |
US11804767B2 (en) | 2018-01-24 | 2023-10-31 | Kardion Gmbh | Magnetic coupling element with a magnetic bearing function |
US12005248B2 (en) | 2018-05-16 | 2024-06-11 | Kardion Gmbh | Rotor bearing system |
JP2021526612A (ja) * | 2018-05-30 | 2021-10-07 | カルディオン ゲーエムベーハーKardion Gmbh | 心臓補助システム用軸流ポンプおよび心臓補助システム用軸流ポンプの製造法 |
US11754075B2 (en) | 2018-07-10 | 2023-09-12 | Kardion Gmbh | Impeller for an implantable, vascular support system |
US11944805B2 (en) | 2020-01-31 | 2024-04-02 | Kardion Gmbh | Pump for delivering a fluid and method of manufacturing a pump |
Also Published As
Publication number | Publication date |
---|---|
WO1985001432A1 (en) | 1985-04-11 |
JPH0531423B2 (ja) | 1993-05-12 |
US4625712A (en) | 1986-12-02 |
BR8407086A (pt) | 1985-08-13 |
CA1240802A (en) | 1988-08-23 |
EP0157871A4 (en) | 1987-09-08 |
EP0157871B1 (en) | 1990-07-04 |
EP0157871A1 (en) | 1985-10-16 |
DE3482656D1 (de) | 1990-08-09 |
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