JPS57128653A - Preparation of alpha-oxyisobutyric acid - Google Patents
Preparation of alpha-oxyisobutyric acidInfo
- Publication number
- JPS57128653A JPS57128653A JP56014666A JP1466681A JPS57128653A JP S57128653 A JPS57128653 A JP S57128653A JP 56014666 A JP56014666 A JP 56014666A JP 1466681 A JP1466681 A JP 1466681A JP S57128653 A JPS57128653 A JP S57128653A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- water
- acetone cyanhydrin
- reaction liquid
- yield
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Abstract
PURPOSE: To prepare α-oxyisobutyric acid useful as a raw material of methacrylic acid, in high yield, by reacting acetone cyanhydrin with specific amounts of sulfuric acid and water, and hydrolyzing the reaction product.
CONSTITUTION: 1mol of acetone cyanhydrin is made to react with 0.5W2.0mol, pref. 0.9W1.2mol of sulfuric acid and 0.2W1.0mol, pref. 0.4W0.6mol of water. Under the above conditions, the side reactions caused by e.g. the decomposition of acetone cyanhydrin and resulting in the lowering of the yield of the objective compound can be suppressed, and the increase of the viscosity of the reaction liquid caused by the amidation reaction is prevented to facilitate the uniform mixing of the reaction liquid. The reaction liquid is hydrolyzed with water. α-Oxyisobutyric acid is prepared from acetone cyanhydrin at a yield of 97W99%. The compound can be converted easily to methacrylic acid by heating and dehydrating in the presence of a catalyst.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56014666A JPS57128653A (en) | 1981-02-03 | 1981-02-03 | Preparation of alpha-oxyisobutyric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56014666A JPS57128653A (en) | 1981-02-03 | 1981-02-03 | Preparation of alpha-oxyisobutyric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57128653A true JPS57128653A (en) | 1982-08-10 |
| JPS6361932B2 JPS6361932B2 (en) | 1988-11-30 |
Family
ID=11867529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56014666A Granted JPS57128653A (en) | 1981-02-03 | 1981-02-03 | Preparation of alpha-oxyisobutyric acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57128653A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02229135A (en) * | 1989-02-28 | 1990-09-11 | Kyowa Gas Chem Ind Co Ltd | Production of 2-hydroxy-4-phenylbutyric acid |
| JP2007522156A (en) * | 2004-02-11 | 2007-08-09 | レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | Process for producing α-hydroxycarboxylic acids and esters thereof |
| JP2007223993A (en) * | 2006-02-27 | 2007-09-06 | Mitsubishi Rayon Co Ltd | Method for producing optically active mandelic acid or its derivative |
| WO2017222043A1 (en) * | 2016-06-24 | 2017-12-28 | 協和発酵バイオ株式会社 | Crystal of β-hydroxy β-methylbutyric acid amino acid salt and production method therefor |
| US10647653B2 (en) | 2015-11-19 | 2020-05-12 | Kyowa Hakko Bio Co., Ltd. | Crystal of monovalent cation salt of 3-hydroxyisovaleric acid and process for producing the crystal |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022084274A1 (en) | 2020-10-23 | 2022-04-28 | Röhm Gmbh | Optimized process for synthesizing methacrylic acid (maa) and/or alkyl methacrylate by reducing unwanted byproducts |
| WO2022084032A1 (en) | 2020-10-23 | 2022-04-28 | Röhm Gmbh | Optimized process for synthesizing alkyl methacrylate by reducing unwanted byproducts |
| WO2023169810A1 (en) | 2022-03-11 | 2023-09-14 | Röhm Gmbh | Process for producing alpha-hydroxyisobutyric acid methyl ester, and its use in the electronics industry |
-
1981
- 1981-02-03 JP JP56014666A patent/JPS57128653A/en active Granted
Non-Patent Citations (1)
| Title |
|---|
| ADVANCED ORGANIC CHEMISTRY=1977 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02229135A (en) * | 1989-02-28 | 1990-09-11 | Kyowa Gas Chem Ind Co Ltd | Production of 2-hydroxy-4-phenylbutyric acid |
| JP2007522156A (en) * | 2004-02-11 | 2007-08-09 | レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | Process for producing α-hydroxycarboxylic acids and esters thereof |
| JP2007223993A (en) * | 2006-02-27 | 2007-09-06 | Mitsubishi Rayon Co Ltd | Method for producing optically active mandelic acid or its derivative |
| US10647653B2 (en) | 2015-11-19 | 2020-05-12 | Kyowa Hakko Bio Co., Ltd. | Crystal of monovalent cation salt of 3-hydroxyisovaleric acid and process for producing the crystal |
| WO2017222043A1 (en) * | 2016-06-24 | 2017-12-28 | 協和発酵バイオ株式会社 | Crystal of β-hydroxy β-methylbutyric acid amino acid salt and production method therefor |
| JPWO2017222043A1 (en) * | 2016-06-24 | 2019-06-20 | 協和発酵バイオ株式会社 | Crystal of 3-hydroxy isovaleric acid amino acid salt and method for producing the same |
| US11098007B2 (en) | 2016-06-24 | 2021-08-24 | Kyowa Hakko Bio Co., Ltd. | Crystal of amino acid salt of 3-hydroxyisovaleric acid and production method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6361932B2 (en) | 1988-11-30 |
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