JPS5653688A - Novel cephalosporin derivative and its preparation - Google Patents

Novel cephalosporin derivative and its preparation

Info

Publication number
JPS5653688A
JPS5653688A JP12927379A JP12927379A JPS5653688A JP S5653688 A JPS5653688 A JP S5653688A JP 12927379 A JP12927379 A JP 12927379A JP 12927379 A JP12927379 A JP 12927379A JP S5653688 A JPS5653688 A JP S5653688A
Authority
JP
Japan
Prior art keywords
compound
formula
preparation
reaction
cephalosporin derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12927379A
Other languages
Japanese (ja)
Inventor
Masahiro Murakami
Masateru Kobayashi
Takanori Sone
Kazuyuki Shibuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP12927379A priority Critical patent/JPS5653688A/en
Publication of JPS5653688A publication Critical patent/JPS5653688A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:7-Glutaramide-3-(benzimidazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid of formula I and its salts.
USE: Synthetic intermediate of drugs: for example, a compound of formula II, which is known as a very strong antibacterial, is derived from the compound in high efficiency and safety.
PREPARATION: A compound of formula III reacts with another compound of formula IV to give the compound of formula I. The reaction is conducted in an aqueous medium or a mix medium containing water and an organic solvent at temperatures of 10W100, preferably 30W80°C. The pH during the reaction is preferably kept to 3W10, much preferably 6W9 and the reaction time is about 30minW10hr.
COPYRIGHT: (C)1981,JPO&Japio
JP12927379A 1979-10-06 1979-10-06 Novel cephalosporin derivative and its preparation Pending JPS5653688A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12927379A JPS5653688A (en) 1979-10-06 1979-10-06 Novel cephalosporin derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12927379A JPS5653688A (en) 1979-10-06 1979-10-06 Novel cephalosporin derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5653688A true JPS5653688A (en) 1981-05-13

Family

ID=15005503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12927379A Pending JPS5653688A (en) 1979-10-06 1979-10-06 Novel cephalosporin derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5653688A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945414A (en) * 1996-12-03 1999-08-31 Antibioticos S.P.A. Process for the preparation of new intermediates useful in the synthesis of cephalosporins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945414A (en) * 1996-12-03 1999-08-31 Antibioticos S.P.A. Process for the preparation of new intermediates useful in the synthesis of cephalosporins

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