JPS554305A - Remedy for disease caused by stress and its preparation - Google Patents
Remedy for disease caused by stress and its preparationInfo
- Publication number
- JPS554305A JPS554305A JP7123678A JP7123678A JPS554305A JP S554305 A JPS554305 A JP S554305A JP 7123678 A JP7123678 A JP 7123678A JP 7123678 A JP7123678 A JP 7123678A JP S554305 A JPS554305 A JP S554305A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- remedy
- stress
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- ZRXHLJNBNWVNIM-UHFFFAOYSA-N 3-methyl-1-benzofuran Chemical compound C1=CC=C2C(C)=COC2=C1 ZRXHLJNBNWVNIM-UHFFFAOYSA-N 0.000 abstract 1
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 abstract 1
- 229910000013 Ammonium bicarbonate Inorganic materials 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 235000012538 ammonium bicarbonate Nutrition 0.000 abstract 1
- 239000001099 ammonium carbonate Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000002622 anti-tumorigenesis Effects 0.000 abstract 1
- 229940053195 antiepileptics hydantoin derivative Drugs 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7123678A JPS554305A (en) | 1978-06-13 | 1978-06-13 | Remedy for disease caused by stress and its preparation |
SU782650052A SU847916A3 (ru) | 1978-06-13 | 1978-08-16 | Способ получени гидантоиновых произ-ВОдНыХ или иХ СОлЕй |
DE7878100683T DE2862404D1 (en) | 1978-06-13 | 1978-08-16 | Hydantoin derivatives, their preparation and pharmaceutical compositions containing them |
EP78100683A EP0006407B1 (en) | 1978-06-13 | 1978-08-16 | Hydantoin derivatives, their preparation and pharmaceutical compositions containing them |
US05/939,791 US4281009A (en) | 1978-06-13 | 1978-09-05 | Hydantoin derivatives |
CA310,821A CA1122602A (en) | 1978-06-13 | 1978-09-07 | Hydantoin derivatives |
AU40200/78A AU520592B2 (en) | 1978-06-13 | 1978-09-26 | Hydantoin derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7123678A JPS554305A (en) | 1978-06-13 | 1978-06-13 | Remedy for disease caused by stress and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS554305A true JPS554305A (en) | 1980-01-12 |
JPS6121471B2 JPS6121471B2 (ja) | 1986-05-27 |
Family
ID=13454848
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7123678A Granted JPS554305A (en) | 1978-06-13 | 1978-06-13 | Remedy for disease caused by stress and its preparation |
Country Status (7)
Country | Link |
---|---|
US (1) | US4281009A (ja) |
EP (1) | EP0006407B1 (ja) |
JP (1) | JPS554305A (ja) |
AU (1) | AU520592B2 (ja) |
CA (1) | CA1122602A (ja) |
DE (1) | DE2862404D1 (ja) |
SU (1) | SU847916A3 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63233946A (ja) * | 1986-12-19 | 1988-09-29 | シエル・アグラー・ゲー・エム・ベー・ハー・ウント・コンパニー・カー・ゲー | ベンゾフエノンおよびその製法 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4672101A (en) * | 1985-09-09 | 1987-06-09 | The Dow Chemical Company | Polyepoxy aromatic hydantoins |
JPH05262654A (ja) * | 1992-03-18 | 1993-10-12 | Kaken Pharmaceut Co Ltd | 慢性疲労症候群治療剤 |
AU754989B2 (en) * | 1998-11-16 | 2002-11-28 | Nippon Zoki Pharmaceutical Co., Ltd. | A therapeutic agent for intractable vasculitis |
JP4711523B2 (ja) | 2001-02-13 | 2011-06-29 | 日本臓器製薬株式会社 | 低アルブミン血症改善剤 |
TWI353979B (en) * | 2002-04-10 | 2011-12-11 | Nippon Zoki Pharmaceutical Co | Novel crystal form of 5-hydroxy-1-methylhydantoin |
WO2003088915A2 (en) * | 2002-04-18 | 2003-10-30 | University Of Virginia Patent Foundation | Novel sodium channel blockers |
US20060241162A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (R)-hydantoin derivative |
US20060241163A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (S)-hydantoin derivative |
US7323536B2 (en) | 2005-05-20 | 2008-01-29 | General Electric Company | Transparent compositions, methods for the preparation thereof, and articles derived therefrom |
US7326764B2 (en) | 2005-05-20 | 2008-02-05 | General Electric Company | Transparent compositions, methods for the preparation thereof, and articles derived therefrom |
ES2769578T3 (es) * | 2013-02-12 | 2020-06-26 | Buck Inst Res Aging | Hidantoínas que modulan el procesamiento de APP mediado por BACE |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6021151A (ja) * | 1983-07-15 | 1985-02-02 | Nisshin Steel Co Ltd | 薄板連続鋳造装置 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2409755A (en) * | 1946-10-22 | Method for obtaining s | ||
CH179695A (de) * | 1934-10-30 | 1935-09-15 | Chem Ind Basel | Verfahren zur Darstellung eines Hydantoins. |
GB644800A (en) * | 1940-09-09 | 1950-10-18 | Parke Davis & Co | Method for obtaining hydantoins |
US2366221A (en) * | 1942-03-13 | 1945-01-02 | James J Spurlock | 5-substituted-5-(2-thienyl) hydantoins |
US2711413A (en) * | 1952-11-19 | 1955-06-21 | Indiana University Foundation | 5-phenyl-5(3-thienyl)-hydantoin and salts thereof |
DE1017172B (de) * | 1956-05-19 | 1957-10-10 | Heyden Chem Fab | Verfahren zur Herstellung von 5-(p-Bromphenyl)-5-aethylhydantoin bzw. dessen 3-methyl- und 3-oxymethylsubstituierten Derivaten |
DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
FR5885M (ja) * | 1966-09-23 | 1968-03-18 | ||
US3577520A (en) * | 1969-12-19 | 1971-05-04 | Emile Constantin Savini | Dentifrice compositions containing 5,5-diaryl - 2,4 -imidazolidinediones and process of treating pyorrhea |
CH587903A5 (ja) * | 1973-05-07 | 1977-05-13 | Ciba Geigy Ag |
-
1978
- 1978-06-13 JP JP7123678A patent/JPS554305A/ja active Granted
- 1978-08-16 EP EP78100683A patent/EP0006407B1/en not_active Expired
- 1978-08-16 SU SU782650052A patent/SU847916A3/ru active
- 1978-08-16 DE DE7878100683T patent/DE2862404D1/de not_active Expired
- 1978-09-05 US US05/939,791 patent/US4281009A/en not_active Expired - Lifetime
- 1978-09-07 CA CA310,821A patent/CA1122602A/en not_active Expired
- 1978-09-26 AU AU40200/78A patent/AU520592B2/en not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6021151A (ja) * | 1983-07-15 | 1985-02-02 | Nisshin Steel Co Ltd | 薄板連続鋳造装置 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63233946A (ja) * | 1986-12-19 | 1988-09-29 | シエル・アグラー・ゲー・エム・ベー・ハー・ウント・コンパニー・カー・ゲー | ベンゾフエノンおよびその製法 |
Also Published As
Publication number | Publication date |
---|---|
AU520592B2 (en) | 1982-02-11 |
CA1122602A (en) | 1982-04-27 |
EP0006407A1 (en) | 1980-01-09 |
US4281009A (en) | 1981-07-28 |
AU4020078A (en) | 1980-04-03 |
DE2862404D1 (en) | 1984-06-20 |
JPS6121471B2 (ja) | 1986-05-27 |
EP0006407B1 (en) | 1984-05-16 |
SU847916A3 (ru) | 1981-07-15 |
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