JPS5535009A - New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component - Google Patents

New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component

Info

Publication number
JPS5535009A
JPS5535009A JP10749278A JP10749278A JPS5535009A JP S5535009 A JPS5535009 A JP S5535009A JP 10749278 A JP10749278 A JP 10749278A JP 10749278 A JP10749278 A JP 10749278A JP S5535009 A JPS5535009 A JP S5535009A
Authority
JP
Japan
Prior art keywords
substance
new antibiotic
soluble
methanol
treated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10749278A
Other languages
Japanese (ja)
Other versions
JPS6230197B2 (en
Inventor
Shigeharu Inoue
Takashi Shomura
Michio Kojima
Mitsuru Hisamatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP10749278A priority Critical patent/JPS5535009A/en
Priority to GB7903605A priority patent/GB2017079B/en
Priority to US06/008,406 priority patent/US4209509A/en
Priority to DE2904628A priority patent/DE2904628C2/en
Priority to FR7903149A priority patent/FR2416899A1/en
Priority to DE2954282A priority patent/DE2954282C2/en
Priority to NLAANVRAGE7904766,A priority patent/NL186514C/en
Priority to CH606479A priority patent/CH642667A5/en
Priority to SE7905693A priority patent/SE445921B/en
Priority to CA330,894A priority patent/CA1105450A/en
Priority to ES482569A priority patent/ES8301500A1/en
Priority to IT24026/79A priority patent/IT1121986B/en
Publication of JPS5535009A publication Critical patent/JPS5535009A/en
Publication of JPS6230197B2 publication Critical patent/JPS6230197B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:Antibiotic SF-1739HP-C. Elemental analysis (%): C 59.58, H 6.14, N 12.63, O 21.65 (rest) ; solubility: easily soluble in water and methanol, soluble in acetone and ethyl acetate and slightly soluble in hexane; Rf value of silica gel thin-layer chromatography: 0.40 (chloroform-methanol = 9:1) and 0.70 (ethyl acetate-methnol = 3:2), dark purple spot. Dark purple substance; does not show clear melting point, and gradually tirns to black from about 120W150°C.
USE: Anticarcinogens having low toxicity, and high antifungal and anticarcinogenic properties.
PROCESS: SF-1739HP substance is obtained by cultivating Streptomyces griseoplanus SF-1739 under aerobic conditions and treating the produced SF-1739 substance (Japanes Patent publication No.51-125798) with an acid. The SF-1739HP is treated with a cyanide to obtain SF-1739HP-C. Or the SF-1739HP is treated with formaldehyde to obtain SF-1739HP-F.
COPYRIGHT: (C)1980,JPO&Japio
JP10749278A 1978-02-08 1978-09-04 New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component Granted JPS5535009A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP10749278A JPS5535009A (en) 1978-09-04 1978-09-04 New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component
GB7903605A GB2017079B (en) 1978-02-08 1979-02-01 Substance sf-1739 derivatives
US06/008,406 US4209509A (en) 1978-02-08 1979-02-01 Substance SF-1739 derivatives, process for preparing the same and antibacterial compositions containing the same
DE2904628A DE2904628C2 (en) 1978-02-08 1979-02-07 Substance SF-1739 HP-C, a process for its preparation and agents with antibacterial and antitumor effects which contain this substance
FR7903149A FR2416899A1 (en) 1978-02-08 1979-02-07 DERIVATIVES OF SUBSTANCE SF-1739, THEIR PREPARATION AND THEIR THERAPEUTIC USES
DE2954282A DE2954282C2 (en) 1978-02-08 1979-02-07 Substance SF-1739 HP, a process for its preparation, and agents with antibacterial and antitumor effects which contain this substance
NLAANVRAGE7904766,A NL186514C (en) 1978-08-16 1979-06-19 DERIVATIVES OF COMPOUND SF-1739, METHODS FOR THE PREPARATION THEREOF, AND ANTIBACTERIAL AND ANTITUMOR PREPARATIONS CONTAINING THESE COMPOUNDS
CH606479A CH642667A5 (en) 1978-08-16 1979-06-28 Derivatives of the substance SF-1739, process for the preparation of such derivatives and antibacterial and cancer-preventing preparations containing such derivatives
SE7905693A SE445921B (en) 1978-08-16 1979-06-28 Derivatives of Substance SF-1739, termed SF-1739 HP-C, PREPARED BY CULTIVATION OF STREPTOMYCES GRISEOPLANUS STEM SF-1739 (ATCC 31451) AND COMPOSITION CONTAINING SUBSTANCE
CA330,894A CA1105450A (en) 1978-08-16 1979-06-29 Substance sf-1739 derivatives, process for preparing the same and antibacterial and antitumor compositions containing the same
ES482569A ES8301500A1 (en) 1978-08-16 1979-06-29 Procedure for the manufacture of antibiotic antibody and antibacterial complexes. (Machine-translation by Google Translate, not legally binding)
IT24026/79A IT1121986B (en) 1978-08-16 1979-06-29 ANTIBACTERIAL AND ANTI-TUMORAL ACTION COMPOUNDS, PROCEDURE FOR MANUFACTURING THEM AND COMPOSITIONS CONTAINING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10749278A JPS5535009A (en) 1978-09-04 1978-09-04 New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component

Publications (2)

Publication Number Publication Date
JPS5535009A true JPS5535009A (en) 1980-03-11
JPS6230197B2 JPS6230197B2 (en) 1987-07-01

Family

ID=14460572

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10749278A Granted JPS5535009A (en) 1978-02-08 1978-09-04 New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component

Country Status (1)

Country Link
JP (1) JPS5535009A (en)

Also Published As

Publication number Publication date
JPS6230197B2 (en) 1987-07-01

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