JPS5535009A - New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component - Google Patents
New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active componentInfo
- Publication number
- JPS5535009A JPS5535009A JP10749278A JP10749278A JPS5535009A JP S5535009 A JPS5535009 A JP S5535009A JP 10749278 A JP10749278 A JP 10749278A JP 10749278 A JP10749278 A JP 10749278A JP S5535009 A JPS5535009 A JP S5535009A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- new antibiotic
- soluble
- methanol
- treated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:Antibiotic SF-1739HP-C. Elemental analysis (%): C 59.58, H 6.14, N 12.63, O 21.65 (rest) ; solubility: easily soluble in water and methanol, soluble in acetone and ethyl acetate and slightly soluble in hexane; Rf value of silica gel thin-layer chromatography: 0.40 (chloroform-methanol = 9:1) and 0.70 (ethyl acetate-methnol = 3:2), dark purple spot. Dark purple substance; does not show clear melting point, and gradually tirns to black from about 120W150°C.
USE: Anticarcinogens having low toxicity, and high antifungal and anticarcinogenic properties.
PROCESS: SF-1739HP substance is obtained by cultivating Streptomyces griseoplanus SF-1739 under aerobic conditions and treating the produced SF-1739 substance (Japanes Patent publication No.51-125798) with an acid. The SF-1739HP is treated with a cyanide to obtain SF-1739HP-C. Or the SF-1739HP is treated with formaldehyde to obtain SF-1739HP-F.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10749278A JPS5535009A (en) | 1978-09-04 | 1978-09-04 | New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component |
GB7903605A GB2017079B (en) | 1978-02-08 | 1979-02-01 | Substance sf-1739 derivatives |
US06/008,406 US4209509A (en) | 1978-02-08 | 1979-02-01 | Substance SF-1739 derivatives, process for preparing the same and antibacterial compositions containing the same |
DE2904628A DE2904628C2 (en) | 1978-02-08 | 1979-02-07 | Substance SF-1739 HP-C, a process for its preparation and agents with antibacterial and antitumor effects which contain this substance |
FR7903149A FR2416899A1 (en) | 1978-02-08 | 1979-02-07 | DERIVATIVES OF SUBSTANCE SF-1739, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
DE2954282A DE2954282C2 (en) | 1978-02-08 | 1979-02-07 | Substance SF-1739 HP, a process for its preparation, and agents with antibacterial and antitumor effects which contain this substance |
NLAANVRAGE7904766,A NL186514C (en) | 1978-08-16 | 1979-06-19 | DERIVATIVES OF COMPOUND SF-1739, METHODS FOR THE PREPARATION THEREOF, AND ANTIBACTERIAL AND ANTITUMOR PREPARATIONS CONTAINING THESE COMPOUNDS |
CH606479A CH642667A5 (en) | 1978-08-16 | 1979-06-28 | Derivatives of the substance SF-1739, process for the preparation of such derivatives and antibacterial and cancer-preventing preparations containing such derivatives |
SE7905693A SE445921B (en) | 1978-08-16 | 1979-06-28 | Derivatives of Substance SF-1739, termed SF-1739 HP-C, PREPARED BY CULTIVATION OF STREPTOMYCES GRISEOPLANUS STEM SF-1739 (ATCC 31451) AND COMPOSITION CONTAINING SUBSTANCE |
CA330,894A CA1105450A (en) | 1978-08-16 | 1979-06-29 | Substance sf-1739 derivatives, process for preparing the same and antibacterial and antitumor compositions containing the same |
ES482569A ES8301500A1 (en) | 1978-08-16 | 1979-06-29 | Procedure for the manufacture of antibiotic antibody and antibacterial complexes. (Machine-translation by Google Translate, not legally binding) |
IT24026/79A IT1121986B (en) | 1978-08-16 | 1979-06-29 | ANTIBACTERIAL AND ANTI-TUMORAL ACTION COMPOUNDS, PROCEDURE FOR MANUFACTURING THEM AND COMPOSITIONS CONTAINING THEM |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10749278A JPS5535009A (en) | 1978-09-04 | 1978-09-04 | New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5535009A true JPS5535009A (en) | 1980-03-11 |
JPS6230197B2 JPS6230197B2 (en) | 1987-07-01 |
Family
ID=14460572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10749278A Granted JPS5535009A (en) | 1978-02-08 | 1978-09-04 | New antibiotic sf-1739hp-c and hp-f, their preparation and anticarcinogen having new antibiotic sf-1739hp-c and hp-f as active component |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5535009A (en) |
-
1978
- 1978-09-04 JP JP10749278A patent/JPS5535009A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6230197B2 (en) | 1987-07-01 |
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