JPS5579396A - Novel antibiotic, sf-2012-l substance, and its preparation - Google Patents
Novel antibiotic, sf-2012-l substance, and its preparationInfo
- Publication number
- JPS5579396A JPS5579396A JP15306478A JP15306478A JPS5579396A JP S5579396 A JPS5579396 A JP S5579396A JP 15306478 A JP15306478 A JP 15306478A JP 15306478 A JP15306478 A JP 15306478A JP S5579396 A JPS5579396 A JP S5579396A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- hydrochloride
- unstable
- acetone
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
NEW MATERIAL:Antibiotic substance, SF-2012-L. Appearance, reddish brown powder; elementary analysis (as hydrochloride), C 48.45%, H 6.67%, N 15.85%, O 21.47%, Fe 3.69%; solubility, easily soluble in water, soluble in methanol, insoluble in ethyl acetate, acetone, etc.; color reaction, Remew reaction positive, ninhydrin reaction negative; stability, relatively stable in an acidic conditions, unstable in neutral or alkaline conditions.
USE: Antibacterial agent having strong activity to gram-positive bacteria.
PROCESS: For example, Streptomyces vinaceus SF-2012 strain (FERM-P No. 4616) is cultured in a liquid medium under aerobic conditions, and the objective substance is absorbed from the filtrate with activated charcoal, etc. The substance is eluted with a 1:1 mixture of water and acetone, and purified to obtain a basic SF-2012-L substance. As the substance is unstable in the form of the free base, it is usually isolated in the form of hydrochloride.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15306478A JPS5579396A (en) | 1978-12-13 | 1978-12-13 | Novel antibiotic, sf-2012-l substance, and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15306478A JPS5579396A (en) | 1978-12-13 | 1978-12-13 | Novel antibiotic, sf-2012-l substance, and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5579396A true JPS5579396A (en) | 1980-06-14 |
Family
ID=15554186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15306478A Pending JPS5579396A (en) | 1978-12-13 | 1978-12-13 | Novel antibiotic, sf-2012-l substance, and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5579396A (en) |
-
1978
- 1978-12-13 JP JP15306478A patent/JPS5579396A/en active Pending
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