JPS55147263A - Novel imidazole derivative - Google Patents
Novel imidazole derivativeInfo
- Publication number
- JPS55147263A JPS55147263A JP5485479A JP5485479A JPS55147263A JP S55147263 A JPS55147263 A JP S55147263A JP 5485479 A JP5485479 A JP 5485479A JP 5485479 A JP5485479 A JP 5485479A JP S55147263 A JPS55147263 A JP S55147263A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- lower alkoxycarbonyl
- imidazole derivative
- novel imidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002460 imidazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- -1 cyanomethyl Chemical group 0.000 abstract 2
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- 206010008111 Cerebral haemorrhage Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I (Y is carboxyl, lower alkoxycarbonyl, hydroxymethyl, or cyanomethyl; A and B are alkylene; n is 0 or 1) and their salts.
EXAMPLE: Ethyl 4-[2-(1-imidazolyl)ethyl]cyclohexane-1-carboxylate.
USE: Remedy for inflammation, hypertension, cerebral hemorrhage, asthma, etc.
PROCESS: The reaction of a compound of formula III (X is halogen; R is lower alkyl) with imidazole gives the compound of formula II (the compound I wherein n=0 and Y is lower alkoxycarbonyl). Hydrolysis, reduction or other treatments of the compound of formula II gives the compound of formula I (wherein n is not 0, and Y is a group other than lower alkoxycarbonyl).
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5485479A JPS55147263A (en) | 1979-05-04 | 1979-05-04 | Novel imidazole derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5485479A JPS55147263A (en) | 1979-05-04 | 1979-05-04 | Novel imidazole derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55147263A true JPS55147263A (en) | 1980-11-17 |
| JPS6327345B2 JPS6327345B2 (en) | 1988-06-02 |
Family
ID=12982171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5485479A Granted JPS55147263A (en) | 1979-05-04 | 1979-05-04 | Novel imidazole derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55147263A (en) |
-
1979
- 1979-05-04 JP JP5485479A patent/JPS55147263A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6327345B2 (en) | 1988-06-02 |
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