JPS5481277A - Pyridine derivative, its preparation, and remedies for circulatory organ - Google Patents
Pyridine derivative, its preparation, and remedies for circulatory organInfo
- Publication number
- JPS5481277A JPS5481277A JP14872577A JP14872577A JPS5481277A JP S5481277 A JPS5481277 A JP S5481277A JP 14872577 A JP14872577 A JP 14872577A JP 14872577 A JP14872577 A JP 14872577A JP S5481277 A JPS5481277 A JP S5481277A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- remedies
- pyridyl
- dihydro
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
Abstract
NEW MATERIAL:A 1-methyl-2-(1,4-dihydro-3,5-dialkoxycarbonyl-2,6-dimethyl-4- pyridyl) pyridinum halide of formula I: (R is lower alkyl group; X is halogen).
EXAMPLE: 1-Methyl-2-(1,4-dihydro-3,5-dimethoxycarbonyl-2,6-dimethyl-4- pyridyl) pyridinium iodide.
USE: Remedies for circulatroy organ diseases, particularly angina pectoris for man. Useful as antiarrythmics and hypotensive agents.
PROCESS: A 2-(1,4-dihydro-3,5-dialkoxycarbonyl-2,6-dimethyl-4-pyridyl) pyridine of formula II is reacted with an excess of a methyl halide of formula III in an organic solvent, e.g. acetonitrile, etc., at a temperature of preferably 10W90°C to form the pyridine derivative of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14872577A JPS5481277A (en) | 1977-12-13 | 1977-12-13 | Pyridine derivative, its preparation, and remedies for circulatory organ |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14872577A JPS5481277A (en) | 1977-12-13 | 1977-12-13 | Pyridine derivative, its preparation, and remedies for circulatory organ |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5481277A true JPS5481277A (en) | 1979-06-28 |
Family
ID=15459205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14872577A Pending JPS5481277A (en) | 1977-12-13 | 1977-12-13 | Pyridine derivative, its preparation, and remedies for circulatory organ |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5481277A (en) |
-
1977
- 1977-12-13 JP JP14872577A patent/JPS5481277A/en active Pending
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