JPS5473775A - Isoxazoline-3-one derivative - Google Patents
Isoxazoline-3-one derivativeInfo
- Publication number
- JPS5473775A JPS5473775A JP13961377A JP13961377A JPS5473775A JP S5473775 A JPS5473775 A JP S5473775A JP 13961377 A JP13961377 A JP 13961377A JP 13961377 A JP13961377 A JP 13961377A JP S5473775 A JPS5473775 A JP S5473775A
- Authority
- JP
- Japan
- Prior art keywords
- isoxazoline
- formula
- derivative
- halogen
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
NEW MATERIAL:An isoxazoline-3-one derivative of formula I: (R1 is halogen; R2 is H, lower alkyl, aryl, or heterocyclic group; R3 is lower alkyl, lower alkenyl, aralkenyl, lower alkynyl, or aralkynyl group).
EXAMPLE: 2-Allyl-4-chloro-5-phenyl-4-isoxazoline-3-one.
USE: Pharmaceuticals having auti-inflammatory, analgesic, and artipyretic actions.
PROCESS: A 3-hydroxy isoxazole of formula I is reacted with a halogen compound of formula III: (X is halogen, e.g. Cl, Br, I, etc.) in an inert solvent, e.g. methanol, benzene, etc. in the presence or absence of a base, e.g. sodium, potassium hydroxides, etc. at 0W150°C, preferably 20W130°C to give the isoxazoline-3-one derivative of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13961377A JPS5473775A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13961377A JPS5473775A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5473775A true JPS5473775A (en) | 1979-06-13 |
Family
ID=15249359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13961377A Pending JPS5473775A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5473775A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0273744A2 (en) * | 1986-12-26 | 1988-07-06 | Sankyo Company Limited | Centrally-acting muscle relaxants |
JPH02132471A (en) * | 1988-11-12 | 1990-05-21 | Ricoh Co Ltd | Copying machine |
JPH02132468A (en) * | 1988-11-12 | 1990-05-21 | Ricoh Co Ltd | Copying machine |
-
1977
- 1977-11-21 JP JP13961377A patent/JPS5473775A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0273744A2 (en) * | 1986-12-26 | 1988-07-06 | Sankyo Company Limited | Centrally-acting muscle relaxants |
JPH02132471A (en) * | 1988-11-12 | 1990-05-21 | Ricoh Co Ltd | Copying machine |
JPH02132468A (en) * | 1988-11-12 | 1990-05-21 | Ricoh Co Ltd | Copying machine |
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