JPH09509085A - 生体再編成可能なコラーゲングラフト補綴物 - Google Patents
生体再編成可能なコラーゲングラフト補綴物Info
- Publication number
- JPH09509085A JPH09509085A JP7521932A JP52193295A JPH09509085A JP H09509085 A JPH09509085 A JP H09509085A JP 7521932 A JP7521932 A JP 7521932A JP 52193295 A JP52193295 A JP 52193295A JP H09509085 A JPH09509085 A JP H09509085A
- Authority
- JP
- Japan
- Prior art keywords
- prosthesis
- layer
- collagen
- diameter
- implanted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/30235—Three-dimensional shapes cylindrical tubular, e.g. sleeves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30971—Laminates, i.e. layered products
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.哺乳類のホストに移植したときに調節された生分解を受け、ついで生細胞に よって十分に置き換えられるか、または新組織形成がなされ、初めに移植された 補綴物が患者の生細胞によって生体再編成されることを特徴とする補綴物。 2.少なくとも2つの層、すなわち、 (a)コラーゲンまたはコラーゲン様材料からなる少なくとも1つの層、および (b)構造的安定性を与え、曲げやすく、半透過性であり、縫合可能である少な くとも1つの層 を備えたことを特徴とする補綴物。 3. 前記層(a)が酸抽出された、好ましくはフィブリル状コラーゲンを含ん で成り、任意的に切断された繊維またはコラーゲン糸を含んで成り;前記層(b )は小腸コラーゲン、生分解生ポリマーシートまたは管、あるいは剛性コラーゲ ンシートまたはメッシュを含んで成ることを特徴とする請求項2記載の補綴物。 4. 小径の内腔を持つ2層の管状補綴物であって、哺乳類のホストに移植した ときに調節された生分解を受け、ついで生細胞によって十分に置き換えられて、 初めに移植された補綴物が患者の生細胞によって生体再編成され、 (a)直径が約50〜約150ミクロンの小腸コラーゲン層からなる、外側( 外腔)の細管化された滅菌された、架橋された構造の層;および (b)内側の酸抽出されたフィブリル状コラーゲン層 を備え、前記補綴物の内腔が6mm未満であることを特徴とする補綴物。 5. 小径の内腔を持つ3層の管状補綴物であって、哺乳類のホストに移植した と きに調節された生分解を受け、ついで生細胞によって十分に置き換えられて、初 めに移植された補綴物が患者の生細胞によって生体再編成され、 (a)酸抽出されたコラーゲンを含んで成る外側(外腔)層; (b)直径が約50〜約150ミクロンの小腸コラーゲン層からなる、滅菌さ れ、架橋された構造の中間層;および (c)内側の酸抽出されたフィブリル状コラーゲン層 を備え、前記補綴物の内腔が6mm未満であることを特徴とする補綴物。 6. 前記コラーゲン層が架橋剤、好ましくは1−エチル−3−(3−ジメチル アミノプロピルカルボジイミド塩酸塩(EDC)で架橋されていることを特徴と する請求項2〜5のいずれかに記載の補綴物。 7. 前記補綴物の前記内腔の直径が6mm未満、場合によっては4mm未満で あることを特徴とする請求項2〜5のいずれかに記載の補綴物。 8. 前記補綴物は、(a)小径動脈または静脈用の移植体;(b)血管貼剤用 の移植体;(c)食道、大腸、尿管、ファロピオ管、動脈および静脈用の代替物 ;(d)食道、大腸、尿管、およびファロピオ管の部分の貼剤;または(e)神 経再成長および再生用の導管に使用するために患者に移植されることを特徴とす る請求項2〜5のいずれかに記載の補綴物。 9.前記コラーゲン様層はさらに抗凝集剤、1種または2種以上の構成物質、一 種または2種以上の成長因子を含有することを特徴とする請求項2に記載の補綴 物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19806294A | 1994-02-18 | 1994-02-18 | |
US08/198,062 | 1994-02-18 | ||
PCT/US1995/002025 WO1995022301A1 (en) | 1994-02-18 | 1995-02-17 | Bioremodelable collagen graft prosthesis |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH09509085A true JPH09509085A (ja) | 1997-09-16 |
JP3765828B2 JP3765828B2 (ja) | 2006-04-12 |
Family
ID=22731845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52193295A Expired - Fee Related JP3765828B2 (ja) | 1994-02-18 | 1995-02-17 | 生体再編成可能なコラーゲングラフト補綴物 |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP0746268B1 (ja) |
JP (1) | JP3765828B2 (ja) |
AT (2) | ATE250901T1 (ja) |
CA (1) | CA2183056C (ja) |
DE (2) | DE69535595T2 (ja) |
MX (1) | MX9603249A (ja) |
WO (1) | WO1995022301A1 (ja) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003527137A (ja) * | 1998-06-05 | 2003-09-16 | オルガノジェネシス インク. | 生物工学的手法による平面シート状移植補綴 |
JP2005528162A (ja) * | 2002-06-03 | 2005-09-22 | エヌエムティー メディカル インコーポレイテッド | 心臓内欠損閉塞のための生物学的組織足場を有するデバイス |
JP2007508900A (ja) * | 2003-10-21 | 2007-04-12 | クック・インコーポレイテッド | 自然組織ステント |
JP2009515569A (ja) * | 2005-10-18 | 2009-04-16 | オーガノジェネシス・インコーポレイテッド | 抗菌性コラーゲン構築物 |
JP2009515620A (ja) * | 2005-11-17 | 2009-04-16 | ゲリタ アクチェンゲゼルシャフト | 神経ガイド |
JP2011206203A (ja) * | 2010-03-29 | 2011-10-20 | Kawasumi Lab Inc | 神経再生チューブ及び神経再生チューブの製造方法 |
WO2012029887A1 (ja) * | 2010-08-31 | 2012-03-08 | 独立行政法人農業生物資源研究所 | 筒状構成物及びその製造方法 |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733337A (en) | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
US20020095218A1 (en) | 1996-03-12 | 2002-07-18 | Carr Robert M. | Tissue repair fabric |
SE9601243D0 (sv) * | 1996-03-29 | 1996-03-29 | Hans Arne Hansson | Promotion of regeneration of organized tissues |
SK22499A3 (en) * | 1996-08-23 | 1999-10-08 | Cook Biotech Inc | Graft prosthesis, materials and methods |
WO1998025546A1 (en) * | 1996-12-10 | 1998-06-18 | Cook Biotech, Inc. | Tubular grafts from purified submucosa |
US5993844A (en) | 1997-05-08 | 1999-11-30 | Organogenesis, Inc. | Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix |
US6004333A (en) * | 1997-10-31 | 1999-12-21 | Ethicon Endo-Surgery, Inc. | Prosthetic with collagen for tissue repair |
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- 1995-02-17 EP EP95911032A patent/EP0746268B1/en not_active Expired - Lifetime
- 1995-02-17 JP JP52193295A patent/JP3765828B2/ja not_active Expired - Fee Related
- 1995-02-17 DE DE69535595T patent/DE69535595T2/de not_active Expired - Lifetime
- 1995-02-17 WO PCT/US1995/002025 patent/WO1995022301A1/en active IP Right Grant
- 1995-02-17 MX MX9603249A patent/MX9603249A/es active IP Right Grant
- 1995-02-17 AT AT95911032T patent/ATE250901T1/de not_active IP Right Cessation
- 1995-02-17 DE DE69531859T patent/DE69531859T2/de not_active Expired - Lifetime
- 1995-02-17 AT AT03019053T patent/ATE372747T1/de not_active IP Right Cessation
- 1995-02-17 EP EP03019053A patent/EP1364627B1/en not_active Expired - Lifetime
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JP2005528162A (ja) * | 2002-06-03 | 2005-09-22 | エヌエムティー メディカル インコーポレイテッド | 心臓内欠損閉塞のための生物学的組織足場を有するデバイス |
JP2010022849A (ja) * | 2002-06-03 | 2010-02-04 | Nmt Medical Inc | 心臓内欠損閉塞のための生物学的組織足場を有するデバイス |
JP2007508900A (ja) * | 2003-10-21 | 2007-04-12 | クック・インコーポレイテッド | 自然組織ステント |
JP4658065B2 (ja) * | 2003-10-21 | 2011-03-23 | クック インコーポレイテッド | 自然組織ステント |
JP2009515569A (ja) * | 2005-10-18 | 2009-04-16 | オーガノジェネシス・インコーポレイテッド | 抗菌性コラーゲン構築物 |
JP2009515620A (ja) * | 2005-11-17 | 2009-04-16 | ゲリタ アクチェンゲゼルシャフト | 神経ガイド |
JP2011206203A (ja) * | 2010-03-29 | 2011-10-20 | Kawasumi Lab Inc | 神経再生チューブ及び神経再生チューブの製造方法 |
WO2012029887A1 (ja) * | 2010-08-31 | 2012-03-08 | 独立行政法人農業生物資源研究所 | 筒状構成物及びその製造方法 |
JP5987138B2 (ja) * | 2010-08-31 | 2016-09-07 | 国立研究開発法人農業・食品産業技術総合研究機構 | 筒状構成物及びその製造方法 |
Also Published As
Publication number | Publication date |
---|---|
EP1364627A1 (en) | 2003-11-26 |
EP1364627B1 (en) | 2007-09-12 |
WO1995022301A1 (en) | 1995-08-24 |
CA2183056C (en) | 2001-07-10 |
DE69531859T2 (de) | 2004-07-29 |
EP0746268B1 (en) | 2003-10-01 |
EP0746268A1 (en) | 1996-12-11 |
EP0746268A4 (en) | 1998-04-01 |
ATE372747T1 (de) | 2007-09-15 |
MX9603249A (es) | 1997-07-31 |
DE69535595D1 (de) | 2007-10-25 |
CA2183056A1 (en) | 1995-08-24 |
JP3765828B2 (ja) | 2006-04-12 |
ATE250901T1 (de) | 2003-10-15 |
DE69535595T2 (de) | 2008-06-05 |
DE69531859D1 (en) | 2003-11-06 |
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