JPH08500846A - 抗エイズ免疫調節剤複合体 - Google Patents
抗エイズ免疫調節剤複合体Info
- Publication number
- JPH08500846A JPH08500846A JP6521725A JP52172594A JPH08500846A JP H08500846 A JPH08500846 A JP H08500846A JP 6521725 A JP6521725 A JP 6521725A JP 52172594 A JP52172594 A JP 52172594A JP H08500846 A JPH08500846 A JP H08500846A
- Authority
- JP
- Japan
- Prior art keywords
- complex
- rna
- production
- amino acid
- immunomodulatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.選択された細菌リボ核酸、選択された細菌膜フラクションーグリコペプチド およびリポ多糖−およびIII型コラーゲンアミノ酸の混合物からなる抗エイズ免 疫調節複合体。 2.標的への結合を確実にするアミノ酸の機能的な腕と、機能的な腕の組成を暗 号化する記述に対応するRNAの遺伝学的な腕のカップルにより構成される2元 分子を含むことを特徴とする請求項1記載の免疫調節複合体。 3.(特にCD4分子への)ウイルス結合部位に対して指向する抗体の産生およ び内因性インターフェロンの産生を特徴とする請求項1又は2記載の免疫調節複 合体。 4.抗HIV抗体のイディオタイプに対する抗イディオタイプワクチン化を血清 陽性患者にもたらし、結果としてP24抗原血症を陰性化する請求項1ないし3 のいずれか1項記載の免疫調節複合体。 5.種々の手段、すなわち注入、静脈注射、皮下注射、経皮装置等により塩化ナ トリウムを添加して投与し得る形態の調製を特徴とする請求項1ないし4のいず れか1項記載の免疫調節複合体。 6.CD4リンパ球減少症に寄与する抗CD4自己免疫反応を阻止または軽減す るための免疫抑制剤を目的とした主要抗炎症剤(コルチコイド型)との同時投与 が可能な形態の調製を特徴とする請求項1ないし5のいずれか1項記載の免疫調 節剤複合体。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR93/03879 | 1993-03-31 | ||
FR9303879A FR2703252B1 (fr) | 1993-03-31 | 1993-03-31 | Complexe immunomodulateur anti SIDA. |
PCT/FR1994/000184 WO1994022462A1 (fr) | 1993-03-31 | 1994-02-18 | Complexe immunomodulateur anti-sida |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH08500846A true JPH08500846A (ja) | 1996-01-30 |
Family
ID=9445666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6521725A Ceased JPH08500846A (ja) | 1993-03-31 | 1994-02-18 | 抗エイズ免疫調節剤複合体 |
Country Status (14)
Country | Link |
---|---|
US (1) | US6503512B1 (ja) |
EP (1) | EP0644773B1 (ja) |
JP (1) | JPH08500846A (ja) |
CN (1) | CN1106202C (ja) |
AT (1) | ATE219680T1 (ja) |
AU (1) | AU6110994A (ja) |
CA (1) | CA2136870C (ja) |
DE (1) | DE69430858T2 (ja) |
DK (1) | DK0644773T3 (ja) |
ES (1) | ES2179067T3 (ja) |
FR (1) | FR2703252B1 (ja) |
MX (1) | MXPA94002284A (ja) |
PT (1) | PT644773E (ja) |
WO (1) | WO1994022462A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011027829A1 (ja) * | 2009-09-02 | 2011-03-10 | 京都府公立大学法人 | 乳酸菌由来のrnaを有効成分とする組成物 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2745186B1 (fr) * | 1996-02-26 | 1998-12-31 | Torossian Fernand Narbey | Complexe immunomodulateur et ses utilisations pour le traitement et la prevention des recidives des affections par helicobacter |
NO311807B1 (no) * | 1999-03-04 | 2002-01-28 | Bionor Immuno As | HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV |
WO2008011884A1 (es) * | 2006-07-27 | 2008-01-31 | Ramirez Castro Angel Dr | Nuevo inmunomodulador |
CN101711165B (zh) * | 2007-03-27 | 2016-02-24 | 以沃尔特里德军事研究所的名义,由美国陆军部部长为代表的美国政府 | 人造侵袭素复合物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2253499B1 (ja) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
FR2388563A1 (fr) * | 1977-04-29 | 1978-11-24 | Fabre Sa Pierre | Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires |
FR2444464A1 (fr) * | 1978-12-19 | 1980-07-18 | Fabre Sa Pierre | Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant |
FR2471785A1 (fr) * | 1979-12-21 | 1981-06-26 | Fabre Sa Pierre | Preparations immunostimulantes a base d'arn ribosomaux et procede de preparation des arn |
DE102010029147B4 (de) * | 2010-05-20 | 2012-04-12 | Semikron Elektronik Gmbh & Co. Kg | Verfahren zur Ermittlung der Temperatur eines Leistungshalbleiters |
-
1993
- 1993-03-31 FR FR9303879A patent/FR2703252B1/fr not_active Expired - Fee Related
-
1994
- 1994-02-18 WO PCT/FR1994/000184 patent/WO1994022462A1/fr active IP Right Grant
- 1994-02-18 DK DK94907595T patent/DK0644773T3/da active
- 1994-02-18 CA CA002136870A patent/CA2136870C/fr not_active Expired - Lifetime
- 1994-02-18 JP JP6521725A patent/JPH08500846A/ja not_active Ceased
- 1994-02-18 US US08/347,322 patent/US6503512B1/en not_active Expired - Lifetime
- 1994-02-18 CN CN94190166A patent/CN1106202C/zh not_active Expired - Lifetime
- 1994-02-18 AT AT94907595T patent/ATE219680T1/de not_active IP Right Cessation
- 1994-02-18 EP EP94907595A patent/EP0644773B1/fr not_active Expired - Lifetime
- 1994-02-18 ES ES94907595T patent/ES2179067T3/es not_active Expired - Lifetime
- 1994-02-18 PT PT94907595T patent/PT644773E/pt unknown
- 1994-02-18 DE DE69430858T patent/DE69430858T2/de not_active Expired - Lifetime
- 1994-02-18 AU AU61109/94A patent/AU6110994A/en not_active Abandoned
- 1994-03-29 MX MXPA94002284A patent/MXPA94002284A/es active IP Right Grant
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011027829A1 (ja) * | 2009-09-02 | 2011-03-10 | 京都府公立大学法人 | 乳酸菌由来のrnaを有効成分とする組成物 |
JPWO2011027829A1 (ja) * | 2009-09-02 | 2013-02-04 | 京都府公立大学法人 | 乳酸菌由来のrnaを有効成分とする組成物 |
US8765706B2 (en) | 2009-09-02 | 2014-07-01 | Kyoto Prefectural Public University Corporation | Composition comprising rna derived from lactic acid bacterium as effective component |
JP5690270B2 (ja) * | 2009-09-02 | 2015-03-25 | 京都府公立大学法人 | 乳酸菌由来のrnaを有効成分とする組成物 |
Also Published As
Publication number | Publication date |
---|---|
CN1106202C (zh) | 2003-04-23 |
DK0644773T3 (da) | 2002-10-07 |
FR2703252B1 (fr) | 1996-09-06 |
WO1994022462A1 (fr) | 1994-10-13 |
CA2136870C (fr) | 2008-11-04 |
MXPA94002284A (es) | 2005-04-01 |
DE69430858T2 (de) | 2003-02-13 |
DE69430858D1 (de) | 2002-08-01 |
CN1106980A (zh) | 1995-08-16 |
EP0644773B1 (fr) | 2002-06-26 |
US6503512B1 (en) | 2003-01-07 |
PT644773E (pt) | 2002-11-29 |
CA2136870A1 (fr) | 1994-10-13 |
EP0644773A1 (fr) | 1995-03-29 |
AU6110994A (en) | 1994-10-24 |
ES2179067T3 (es) | 2003-01-16 |
FR2703252A1 (fr) | 1994-10-07 |
ATE219680T1 (de) | 2002-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050111 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20050411 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20050530 |
|
A313 | Final decision of rejection without a dissenting response from the applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A313 Effective date: 20050822 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20050927 |