JPH0530492B2 - - Google Patents

Info

Publication number
JPH0530492B2
JPH0530492B2 JP57120596A JP12059682A JPH0530492B2 JP H0530492 B2 JPH0530492 B2 JP H0530492B2 JP 57120596 A JP57120596 A JP 57120596A JP 12059682 A JP12059682 A JP 12059682A JP H0530492 B2 JPH0530492 B2 JP H0530492B2
Authority
JP
Japan
Prior art keywords
test tube
rollers
holder
stirring device
stirring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57120596A
Other languages
Japanese (ja)
Other versions
JPS5912740A (en
Inventor
Hidenori Noso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP57120596A priority Critical patent/JPS5912740A/en
Priority to US06/511,947 priority patent/US4518264A/en
Priority to EP83106806A priority patent/EP0099103B1/en
Priority to EP89113165A priority patent/EP0344819A1/en
Priority to DE8383106806T priority patent/DE3381981D1/en
Priority to CA000432373A priority patent/CA1245214A/en
Publication of JPS5912740A publication Critical patent/JPS5912740A/en
Priority to CA000550021A priority patent/CA1259048A/en
Publication of JPH0530492B2 publication Critical patent/JPH0530492B2/ja
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/275Mixing the contents of independent containers, e.g. test tubes with means for transporting test tubes to and from the stirring device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00524Mixing by agitating sample carrier
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0406Individual bottles or tubes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Description

【発明の詳細な説明】 本発明は撹拌装置に関し、更に詳細には試験管
に採取された血液を検査装置へ供給する際試験管
内の血液を均一な懸濁状態に撹拌する装置に関す
る。
DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a stirring device, and more particularly to a device for stirring blood collected in a test tube into a uniform suspension state when the blood is supplied to a testing device.

現在、レーザー技術とコンピユーター技術との
組み合わせによつて赤血球数、白血球数、血小板
数、赤血球色素濃度、ヘマトクリツト値等を再現
性よく且つ高い正確度で測定する血液検査装置が
知られている。このような検査装置で血液を検査
する際には、血液を入れた試験管を当該検査装置
の測定検体セツト位置へ置き、ここで検査装置か
ら延びるアスピレーターによつて試験管内検体が
吸引され、測定部へ供給される。
BACKGROUND ART Currently, blood test devices are known that measure red blood cell counts, white blood cell counts, platelet counts, red blood cell pigment concentrations, hematocrit values, etc. with good reproducibility and high accuracy using a combination of laser technology and computer technology. When testing blood with such a test device, a test tube containing blood is placed at the measurement sample set position of the test device, and the sample in the test tube is aspirated by an aspirator extending from the test device, and the sample is then measured. supplied to the department.

ところで、この血液検査装置に検体たる血液を
供給する場合、前記アスピレーターによる吸引直
前の試験管内血液は、均一な懸濁状態が保たれて
いる必要がある。そのため従来では、検査員が自
らその手で試験管底部を振り、撹拌を行なつてい
た。しかしながら、このような人手による撹拌操
作は、各試験管ごとに撹拌状態に大きなばらつき
を生じ撹拌の均一化が得られないことと、赤血
球、白血球等を壊さないで良好な懸濁状態を得る
ような撹拌を行なうにはかなりの熟練を必要とす
ることなどの欠点があつた。更に、このような人
手による撹拌操作では、緊急に血液の検査をする
時は別として、病院等で多数の患者の血液を随時
検査する場合何百という数の検体を処理しなけれ
ばならず、このような時、その撹拌作業に多数の
検査員およびこれらの者の著しい労力と時間を費
やさなければならないという問題があつた。
By the way, when blood as a specimen is supplied to this blood test apparatus, the blood in the test tube immediately before being sucked by the aspirator needs to be kept in a uniform suspended state. For this reason, in the past, inspectors had to shake the bottoms of test tubes with their hands to stir the test tubes. However, such manual stirring operations result in large variations in the stirring conditions for each test tube, making it impossible to achieve uniform stirring, and it is difficult to obtain a good suspension state without destroying red blood cells, white blood cells, etc. The drawback was that it required considerable skill to perform proper stirring. Furthermore, with such manual stirring operations, apart from when conducting an emergency blood test, hundreds of specimens must be processed when the blood of a large number of patients is tested at any time at a hospital, etc. In such cases, there is a problem in that a large number of inspectors and their considerable effort and time must be spent on the stirring work.

従つて、本発明の目的は、試験管底部を振つて
該試験管内部の試料を撹拌する装置を提供するこ
とにある。
Therefore, an object of the present invention is to provide an apparatus for stirring the sample inside the test tube by shaking the bottom of the test tube.

本発明の撹拌装置を要約すると、試料を収容す
る試験管を回転可能に支持するホルダーと、該ホ
ルダーを揺動可能に支持する装置と、前記試験管
を正回転および逆回転させつつ揺動させる装置と
を含み、前記試験管を正回転および逆回転させつ
つ揺動させる装置が、前記試験管の頭部付近で間
隔をあけて配置され且つそれぞれ相反する方向に
回転する2つのローラと、該2つのローラと前記
試験管とにおいて該試験管頭部が前記2つのロー
ラの周縁に交互に当接するようにその一方を他方
に対して相対的に往復動させる装置とを含んで構
成される。
To summarize the stirring device of the present invention, it includes a holder that rotatably supports a test tube containing a sample, a device that swingably supports the holder, and a device that swings the test tube while rotating forward and backward. a device for rocking the test tube while rotating it in forward and reverse directions; The apparatus includes two rollers and a device for reciprocating one of the test tubes relative to the other so that the test tube heads alternately abut against the peripheral edges of the two rollers.

以下、本発明の撹拌装置を添付図面に示された
好適な実施例を参照して更に詳細に説明する。
Hereinafter, the stirring device of the present invention will be explained in more detail with reference to preferred embodiments shown in the accompanying drawings.

第1図〜第3図には、本発明の撹拌装置の一実
施例が示されている。この実施例における撹拌装
置10は、同一平面内に間隔をあけて配置された
2つのローラ11a,11bを有し且つこれらを
回転可能に支持するユニツト12を含む。すなわ
ち、このローラ支持ユニツト(以下単にユニツト
と称す)12は、垂直方向に伸長し且つ並行に配
置された2つの軸13a,13bを軸受し、ユニ
ツト12の下面から突出する各軸13a,13b
の下端にはそれぞれ周囲にゴム製のリング部材1
4a,14bを取付けたローラ11a,11bが
固定されている。また、これらの軸13a,13
bの上端にはユニツト12の内部でそれぞれ歯車
15a,15bが固定され、これら歯車15a,
15bは2つのアイドルギヤ15c,15dを介
して作動的に連結されている。これにより、一方
のローラ11aが回転すると、その回転は歯車列
15a〜15dを介して他方のローラ11bに伝
達され、且つ両ローラ11a,11bは相反する
方向に回転する。
1 to 3 show an embodiment of the stirring device of the present invention. The stirring device 10 in this embodiment includes a unit 12 having two rollers 11a, 11b arranged at a distance in the same plane and rotatably supporting these rollers. That is, this roller support unit (hereinafter simply referred to as the unit) 12 bears two shafts 13a, 13b extending in the vertical direction and arranged in parallel, and each shaft 13a, 13b protruding from the lower surface of the unit 12.
There is a rubber ring member 1 around the bottom edge of each
Rollers 11a and 11b with attached rollers 4a and 14b are fixed. In addition, these shafts 13a, 13
Gears 15a, 15b are fixed to the upper end of the unit 12, respectively.
15b are operatively connected via two idle gears 15c and 15d. As a result, when one roller 11a rotates, the rotation is transmitted to the other roller 11b via the gear trains 15a to 15d, and both rollers 11a and 11b rotate in opposite directions.

このユニツト12には2本のガイド棒16a,
16bが固定され、該ガイド棒16a,16bは
ローラ整列方向のユニツト側壁から当該方向外方
へ伸長している。そして、このガイド棒16a,
16bは、本撹拌装置10の適当な固定支持壁1
7から突出した担持部18に形成された孔に緊密
に且つスライド可能に挿通されている。これによ
り、2つのローラ11a,11bを有するユニツ
ト12は該ローラの整列方向に移動可能に担持さ
れている。
This unit 12 has two guide rods 16a,
16b is fixed, and the guide rods 16a, 16b extend outwardly from the side wall of the unit in the roller alignment direction. And this guide rod 16a,
16b is a suitable fixed support wall 1 of the stirring device 10;
The support member 18 is tightly and slidably inserted into a hole formed in a support member 18 protruding from the support member 7 . Thereby, the unit 12 having the two rollers 11a, 11b is supported so as to be movable in the direction in which the rollers are aligned.

次に、前記ユニツト12をスライド可能に支持
している担持部18の下方には、前記固定支持壁
17に取付けられたギヤボツクス19が配置さ
れ、その下面には駆動源即ちモータ20が取付け
られている。このモータ20の駆動軸はギヤボツ
クス19内の減速歯車列21の入力側歯車に連結
され、他方、出力側歯車に連結された軸22は、
ギヤボツクス19の上面に不動に固着された平歯
車23の中心孔を遊貫して上方に伸長し、その上
端には円板24が固定されている。この円板24
上の径方向外方位置即ち偏心位置には短い軸25
が該円板24を貫通して且つ回転可能に取付けら
れ、円板24の下面側へ突出した軸25の下端に
は、前述した固定の平歯車23に噛合つた歯車2
6が固着され、また軸25の上端には板状の作動
ロツド27の一端が遊嵌されると共に更にプーリ
29が固着されている。一方、前述したユニツト
12のローラ11a下面には該ローラと回転中心
軸線を一致させて密着固定されたプーリ30が設
けられ、更にこのローラ11aおよびプーリ30
を介して下方へ伸長した軸13aの下端には前記
作動ロツド27の他端が遊嵌されている。そし
て、前記2つのプーリ29,30にはゴムベルト
31が掛けられ、プーリ29の回転をプーリ30
へ伝達する。これらの状態は第1図における−
線および−線に沿つて得た各断面図(第4
図、第5図)により明瞭に示されている。
Next, a gearbox 19 attached to the fixed support wall 17 is disposed below the support part 18 that slidably supports the unit 12, and a drive source, that is, a motor 20 is attached to the lower surface of the gearbox 19. There is. The drive shaft of this motor 20 is connected to the input side gear of a reduction gear train 21 in the gearbox 19, while the shaft 22 connected to the output side gear is
The spur gear 23 extends upwardly through a center hole of a spur gear 23 which is immovably fixed to the upper surface of the gearbox 19, and a disk 24 is fixed to the upper end of the spur gear 23. This disk 24
In the upper radially outer or eccentric position there is a short shaft 25.
is rotatably attached to the shaft 25 passing through the disk 24, and protruding toward the lower surface of the disk 24. At the lower end of the shaft 25, there is a gear 2 meshing with the fixed spur gear 23 mentioned above.
One end of a plate-shaped actuating rod 27 is loosely fitted to the upper end of the shaft 25, and a pulley 29 is further fixed. On the other hand, a pulley 30 is provided on the lower surface of the roller 11a of the unit 12 described above, and the pulley 30 is closely fixed to the roller with its rotation center axis aligned with the roller.
The other end of the actuating rod 27 is loosely fitted to the lower end of the shaft 13a which extends downward through the shaft 13a. A rubber belt 31 is placed over the two pulleys 29 and 30, and the rotation of the pulley 29 is controlled by the pulley 30.
Communicate to. These states are - in Figure 1.
Each cross-sectional view taken along the line and - line (fourth
5).

更に、ユニツト12における2つのローラ11
a,11bの間隔には、試験管32がこれを回転
可能に且つ揺動可能に支持する装置33によつて
配置されている。この詳細は第6図及び第7図に
示されている、この第6図を参照して説明する
と、試験管32は、該管の外径より幾分大きな内
径の受け孔を有する柱状のホルダー34のその受
け孔にほぼ下半分が入れられて支持されている。
従つて、この試験管32は、そのホルダー34に
対してその受け孔内で長手方向中心軸線を中心に
回転可能である。また、このホルダー34は試験
管32の回転に対してできる限り摩擦を小さくす
るように摩擦係数の非常に小さな材質、例えばジ
ラコン樹脂などから形成することが好ましい。
Furthermore, the two rollers 11 in the unit 12
A test tube 32 is disposed in the space between a and 11b by means of a device 33 that supports it rotatably and swingably. Details of this are shown in FIGS. 6 and 7. Referring to FIG. 6, the test tube 32 is arranged in a columnar holder having a receiving hole with an inner diameter somewhat larger than the outer diameter of the tube. Almost the lower half is inserted into the receiving hole of 34 and supported.
The test tube 32 is therefore rotatable about its central longitudinal axis within its receiving hole relative to its holder 34. Further, it is preferable that the holder 34 be made of a material with a very small coefficient of friction, such as ziracon resin, so as to reduce the friction as much as possible against the rotation of the test tube 32.

この柱状のホルダー34は、ホルダー保持部材
であつて一対の対向側壁35a,35bと底壁3
5cとのみから成り、上端と他の一対の側部とを
開放したコ字状のホルダー保持部材(以下単に保
持部材と称す)35に収容される。この保持部材
35の一方の側壁35aの上部であつてホルダー
34を介して位置決めされた試験管32の高さの
半分より上方の位置には、支持部材36の上端に
形成された開口に遊挿されたピン37の突出先端
が止ねじ38によつて固定されている。このピン
37の頭部は支持部材36の開口より大きな径の
フランジを備えているため、該ピン37がその開
口から抜け出ることはなく且つ自由に回転可能で
ある。従つて、保持部材35はピン37を枢軸と
して支持部材36に対して揺動可能とされてい
る。この支持部材36の下端は支持ロツド39に
固定されている。
This columnar holder 34 is a holder holding member and has a pair of opposing side walls 35a, 35b and a bottom wall 3.
5c, and is housed in a U-shaped holder holding member (hereinafter simply referred to as a holding member) 35 with an open upper end and the other pair of sides. At a position above half of the height of the test tube 32 positioned via the holder 34 at the upper part of one side wall 35a of the holding member 35, the test tube 32 is loosely inserted into an opening formed at the upper end of the support member 36. The protruding tip of the pin 37 is fixed by a set screw 38. Since the head of the pin 37 is provided with a flange having a diameter larger than the opening of the support member 36, the pin 37 does not slip out of the opening and can freely rotate. Therefore, the holding member 35 can swing relative to the supporting member 36 about the pin 37. The lower end of this support member 36 is fixed to a support rod 39.

前記保持部材35には、開放した一対の対向側
部を開閉するための保護カバー40が取付けられ
ている。この保護カバー40は、横断面u形状の
部材から成り、保持部材35の他方の側壁35b
から当該保持部材の開放側部を被うように装着さ
れる。この保護カバー40は、ホルダー34の保
持部材35からの脱落を防止するためだけのもの
であるため保持部材35の高さのほぼ半分より幾
分長い程度の高さ寸法を持ち、その下端部におい
て保持部材35に取付けられている。すなわち、
保持部材35の底壁35cに当該部分を横断して
形成された孔41は支持部材36側からある長さ
だけ大径の孔41aとされ、これより側壁35b
へは小径の孔41bとされている。この大径の孔
41a内にはコイル状のばね42が挿入され、こ
のばね42の内側空間を貫通して取付けロツド4
3が前記孔41内に挿通されその側壁35b側端
部は保護カバー40の側壁35bに当接する壁部
に固定されている。また、前記取付けロツド43
の他端は、大径の孔41a内へは進入し得るが、
その際にはばね42の端部からこれを圧縮するよ
うな大径頭部を備えている。これにより、この保
護カバー40はばね42の弾発力によつて常に第
6図に示されるような装着状態を保持しようとす
ると共に、第7図に示すように保護カバー40を
側壁35b側から引き出せば保持部材35の開放
側部を開けることができる。
A protective cover 40 is attached to the holding member 35 for opening and closing the pair of open opposing sides. This protective cover 40 is made of a member having a U-shaped cross section, and includes the other side wall 35b of the holding member 35.
It is attached so as to cover the open side of the holding member. Since this protective cover 40 is only for preventing the holder 34 from falling off from the holding member 35, it has a height dimension that is slightly longer than approximately half the height of the holding member 35, and has a height dimension that is slightly longer than approximately half the height of the holding member 35, and its lower end It is attached to the holding member 35. That is,
A hole 41 formed across the bottom wall 35c of the holding member 35 is a hole 41a having a larger diameter by a certain length from the support member 36 side, and from this, the side wall 35b
A small diameter hole 41b is formed into the hole 41b. A coiled spring 42 is inserted into this large diameter hole 41a, and the mounting rod 4 is inserted through the inner space of this spring 42.
3 is inserted into the hole 41, and its end on the side wall 35b is fixed to a wall portion that abuts the side wall 35b of the protective cover 40. In addition, the mounting rod 43
The other end can enter into the large diameter hole 41a, but
In this case, a large-diameter head is provided to compress the spring 42 from its end. As a result, the protective cover 40 always tries to maintain the attached state as shown in FIG. 6 due to the elastic force of the spring 42, and the protective cover 40 is pushed from the side wall 35b side as shown in FIG. By pulling it out, the open side of the holding member 35 can be opened.

このように構成された撹拌装置10の作動を次
に説明する。
The operation of the stirring device 10 configured as described above will be explained next.

最初に検体血液を入れた試験管32が準備さ
れ、該試験管はホルダー34の受け孔内に入れら
れ、次いでこのホルダー34は、保持部材35に
取付けられた保護カバー40を引き出して該保持
部材の側部を開放し、この開放側部から保持部材
内に配置される。そして、この試験管32は、支
持ロツド39を前進させることによつてその頭部
を第1図に示されるように2つのローラ11a,
11b間の整列線(中心を結ぶ線)上に位置決め
される。
First, a test tube 32 containing sample blood is prepared, and the test tube is placed into the receiving hole of the holder 34. Next, the holder 34 pulls out the protective cover 40 attached to the holding member 35 and removes the protective cover 40 attached to the holding member 35. has an open side and is placed into the holding member from this open side. By advancing the support rod 39, the test tube 32 is moved between two rollers 11a and 11a, as shown in FIG.
11b on the alignment line (line connecting the centers).

その後、モータ20が起動されると、該モータ
の回転は減速歯車列21を介して軸22に伝達さ
れ、これにより円板24が回転される。この円板
24の回転によつて該円板24の偏心位置に取付
けられた軸25は、当該円板24の回転中心軸線
の周囲を回転(公転)すると共にこの公転により
不動の歯車23に噛合つた軸25下端の歯車26
が回転してこの軸25も自ら回転(自転)する。
これにより、第4図および第5図に示されるよう
に、スライド可能に支持されたユニツト12は、
作動ロツド27のクランク運動により往復運動さ
せられる。これと同時に軸25の回転即ち自転は
プーリ29,30およびゴムベルト31を介して
ローラ11aに伝達される。このローラ11aの
回転はユニツト12内の歯車列15a〜15dを
介して他のローラ11bに伝達され、且つこの2
つのローラ11a,11bは前述したようにそれ
ぞれ相反する方向に回転する。
Thereafter, when the motor 20 is started, the rotation of the motor is transmitted to the shaft 22 via the reduction gear train 21, thereby rotating the disk 24. As the disc 24 rotates, the shaft 25 attached to the eccentric position of the disc 24 rotates (revolutions) around the central axis of rotation of the disc 24 and meshes with the stationary gear 23 due to this revolution. Gear 26 at the lower end of the shaft 25
rotates, and this shaft 25 also rotates (rotates on its own axis).
As a result, as shown in FIGS. 4 and 5, the slidably supported unit 12 is
It is caused to reciprocate by cranking the actuating rod 27. At the same time, the rotation of the shaft 25, that is, its rotation, is transmitted to the roller 11a via the pulleys 29, 30 and the rubber belt 31. The rotation of this roller 11a is transmitted to the other roller 11b via gear trains 15a to 15d in the unit 12, and
As described above, the two rollers 11a and 11b rotate in opposite directions.

このようにして、ユニツト12の2つのローラ
11a,11bはその整列方向に往復動しながら
自らも回転をする。この結果、第3図に示すよう
にローラ11a,11b間に頭部を位置決めされ
て揺動可能に支持された試験管32は、ユニツト
12の往復動ごとに各ローラ11a,11bによ
つて側方へ押し倒されるようにしてホルダー34
および保持部材35ごとピン37を枢軸として揺
動される。その際、試験管32は、その頭部が各
ローラ11a,11bに交互に当接するたびにそ
の当接したローラとの摩擦係合によつて回転力を
受けてホルダー34内で回転する。この試験管3
2の回転は、前述したように各ローラ11a,1
1bの回転方向がそれぞれ逆方向であるため、当
接するローラが変わるごとにその方向を逆にす
る。従つて、試験管32は、揺動しながらそれ自
身も正転および逆転をする。この時、試験管32
の揺動支点(ピン37の位置)が試験管に対して
その高さの半分より上方位置にあるようにされて
いるため、特に試験管底部が大きく振れる。これ
によつて、試験管32内の血液は赤血球、白血球
等を破壊することなく良好な懸濁状態に撹拌され
且つ試験管ごとのばらつきも生ずることがない。
In this way, the two rollers 11a and 11b of the unit 12 rotate themselves while reciprocating in the alignment direction. As a result, as shown in FIG. 3, the test tube 32, whose head is positioned between the rollers 11a and 11b and is swingably supported, is moved to the side by each roller 11a and 11b each time the unit 12 moves back and forth. The holder 34 is pushed down toward the
And the holding member 35 is swung about the pin 37 as a pivot. At this time, each time the test tube 32 makes contact with each of the rollers 11a and 11b alternately, the test tube 32 receives a rotational force due to frictional engagement with the rollers and rotates within the holder 34. This test tube 3
2, the rotation of each roller 11a, 1 as described above.
Since the rotation directions of the rollers 1b are opposite to each other, the directions are reversed each time the rollers in contact change. Therefore, the test tube 32 also rotates forward and backward while swinging. At this time, test tube 32
Since the swing fulcrum (the position of the pin 37) is located above half of the height of the test tube, the bottom of the test tube in particular swings significantly. As a result, the blood in the test tube 32 is stirred into a good suspended state without destroying red blood cells, white blood cells, etc., and there is no variation between test tubes.

このようにして撹拌操作が一定時間経過する
と、再び第1図の状態に戻り、次いで、試験管を
揺動支持する装置33は、支持ロツド39の伸長
によつてそのままユニツト12下を通過して第1
図でみてユニツト12の後方(第2図に仮想線で
示されている)に配置されている血液検査装置5
0の測定検体セツト位置51へ前進させられ、そ
の試験管内へ血液検査装置50のアスピレーター
(図示せず)が入り込み、試験管内の血液を一部
だけ吸い込み、その各種測定が行なわれる。
After the stirring operation has continued for a certain period of time, the state shown in FIG. 1st
Blood test device 5 located behind the unit 12 in the figure (indicated by phantom lines in FIG. 2)
The aspirator (not shown) of the blood test device 50 enters into the test tube, sucks only a portion of the blood in the test tube, and performs various measurements.

前述した実施例の撹拌装置10では、2つのロ
ーラ11a,11bの整列方向への往復動によつ
て試験管を揺動させるものであつたが、これに限
定されるものではない。例えば、第8図に示され
る他の実施例のように、試験管を揺動可能に支持
する装置33の移動線上両側にローラ45a,4
5bを少なくとも2つ千鳥状に配置してこれらの
ローラをそれぞれ相反する方向に回転させ、次い
で試験管を揺動可能に支持する装置33を前進さ
せて試験管の頭部をローラ45a,45bに交互
に当接させることによつても同様な効果が得られ
る。
In the stirring device 10 of the embodiment described above, the test tube is oscillated by the reciprocating motion of the two rollers 11a and 11b in the alignment direction, but the present invention is not limited to this. For example, as in another embodiment shown in FIG.
At least two rollers 5b are arranged in a staggered manner and these rollers are rotated in opposite directions, and then the device 33 that swingably supports the test tube is advanced to move the head of the test tube onto the rollers 45a and 45b. A similar effect can be obtained by making them contact each other alternately.

また、最初に説明した実施例におけるホルダー
34は、柱状のものにその上端面から試験管外径
より大きな内径の縦長凹部を形成して成るもので
あつたが、第9図に示されるようなものでもよ
い。第9図に示される別な例のホルダー46は、
上下にそれぞれ張出し部47a,47bを有する
コ字状のもので、上方の張出し部47aには試験
管が遊挿可能な開口48が形成され、又下方の張
出し部47bには試験管底部を受けるための皿状
の凹所49が形成されている。このようなホルダ
ー46によれば、試験管とホルダーとの接触部が
非常に少ないので試験管の回転がスムーズに行な
える利点を有する。
In addition, the holder 34 in the first embodiment described was a columnar member with a vertically elongated recessed portion having an inner diameter larger than the outer diameter of the test tube formed from the upper end surface of the holder 34, but as shown in FIG. It can be anything. Another example of the holder 46 shown in FIG.
It is U-shaped with upper and lower overhangs 47a and 47b, respectively, with the upper overhang 47a having an opening 48 into which a test tube can be loosely inserted, and the lower overhang 47b receiving the bottom of the test tube. A dish-shaped recess 49 is formed for this purpose. Such a holder 46 has the advantage that the test tube can be rotated smoothly because there are very few contact parts between the test tube and the holder.

更にまた、第10図に示すように、ホルダー5
0の外側部に凹溝51を設け、該凹溝に保持部材
52に設けられた出入自在のピンを係合させ、保
持部材52にホルダー50を保持するような機構
を採用することもできる。
Furthermore, as shown in FIG.
It is also possible to adopt a mechanism in which a recessed groove 51 is provided on the outer side of the holder 50, a removable pin provided on a holding member 52 is engaged with the recessed groove, and the holder 50 is held on the holding member 52.

叙上の如く、本発明の撹拌装置によれば、従来
手で行なつていた撹拌操作が機械的に行なえるた
め多数の数の検体を処理する時大幅な省力化を達
成できる。しかも、各試験管ごとの撹拌状態にば
らつきが生じないため撹拌の均一化が得られ且つ
良好な懸濁状態とすることができる。
As described above, according to the stirring device of the present invention, the stirring operation that was conventionally performed by hand can be performed mechanically, so that significant labor savings can be achieved when processing a large number of samples. Moreover, since there is no variation in the stirring state for each test tube, uniform stirring can be obtained and a good suspension state can be achieved.

【図面の簡単な説明】[Brief explanation of the drawing]

第1図は本発明の撹拌装置の一実施例を示す正
面図、第2図は第1図に示された撹拌装置の平面
図、第3図は第1図に示した装置の作動状態を示
す説明図、第4図および第5図は第1図の−
線および−線に沿つて得た断面図、第6図は
試験管を揺動可能に支持する装置を示す縦断面
図、第7図は第6図に示した装置の保護カバーを
開いた状態を示す第6図と同様の図面、第8図は
本発明の撹拌装置における他の実施例において試
験管を揺動可能に支持する装置と2つのローラと
の関係を概略的に示す平面図、および第9図はホ
ルダーの別の実施例を示す斜視図、第10図はホ
ルダーと保持部材の他の一例を示す斜視図であ
る。 10……撹拌装置、11a,11b……ロー
ラ、23……平歯車、24……円板、25……
軸、26……歯車、27……作動ロツド、29,
30……プーリ、31……ゴムベルト、32……
試験管、33……揺動可能に支持する装置、34
……ホルダー、37……ピン。
Fig. 1 is a front view showing one embodiment of the stirring device of the present invention, Fig. 2 is a plan view of the stirring device shown in Fig. 1, and Fig. 3 shows the operating state of the device shown in Fig. 1. The explanatory diagrams shown in Figs. 4 and 5 are - of Fig. 1.
6 is a longitudinal sectional view showing a device for swingably supporting a test tube, and FIG. 7 is a state in which the protective cover of the device shown in FIG. 6 is opened. FIG. 8 is a plan view schematically showing the relationship between a device that swingably supports a test tube and two rollers in another embodiment of the stirring device of the present invention; 9 is a perspective view showing another embodiment of the holder, and FIG. 10 is a perspective view showing another example of the holder and the holding member. 10... Stirring device, 11a, 11b... Roller, 23... Spur gear, 24... Disc, 25...
Shaft, 26...gear, 27...operating rod, 29,
30...Pulley, 31...Rubber belt, 32...
Test tube, 33...Swivelably supporting device, 34
...Holder, 37...Pin.

Claims (1)

【特許請求の範囲】 1 試料を収容する試験管を該試験管の長手方向
中心軸線を中心に回転可能に支持するホルダー
と、該ホルダーを揺動可能に支持する装置と、前
記試験管を正回転および逆回転させつつ揺動させ
る装置とを含み、前記試験管を正回転および逆回
転させつつ揺動させる装置が、前記試験管の頭部
付近で間隔をあけて配置され且つそれぞれ相反す
る方向に回転する2つのローラと、該2つのロー
ラと前記試験管とにおいて該試験管頭部が前記2
つのローラの周縁に交互に当接するようにその一
方を他方に対して相対的に往復動させる装置とを
含む撹拌装置。 2 特許請求の範囲第1項に記載の撹拌装置にお
いて、前記2つのローラが同一平面上に配置され
且つ前記試験管が前記2つのローラの軸間距離線
上を該2つのローラに対して相対的に往復動する
ことを特徴とする撹拌装置。 3 特許請求の範囲第1項又は第2項に記載の撹
拌装置において、前記ホルダーを揺動可能に支持
する装置が、前記ホルダーに支持された前記試験
管に対する揺動支点を該試験管の長さの半分より
上方に置くように設定された枢着部を備えている
ことを特徴とする撹拌装置。 4 特許請求の範囲第1項、第2項又は第3項に
記載の撹拌装置において、前記試験管内に収容さ
れる試料が血液であることを特徴とする撹拌装
置。
[Scope of Claims] 1. A holder that rotatably supports a test tube containing a sample about the longitudinal central axis of the test tube, a device that swingably supports the holder, and a device that supports the test tube in a manner that allows the test tube to be and a device for rocking the test tube while rotating and reversely rotating the test tube, the devices for rocking the test tube while rotating and reversely rotating the test tube, the devices being arranged at intervals near the head of the test tube and in opposite directions, respectively. between the two rollers and the test tube, the head of the test tube is
a device for reciprocating one roller relative to the other so as to alternately abut the peripheral edges of the two rollers. 2. In the stirring device according to claim 1, the two rollers are arranged on the same plane, and the test tube is positioned on the axis distance line of the two rollers relative to the two rollers. A stirring device characterized by reciprocating motion. 3. In the stirring device according to claim 1 or 2, a device that swingably supports the holder is arranged such that a swinging fulcrum for the test tube supported by the holder is aligned with the length of the test tube. A stirring device characterized by comprising a pivot portion set to be placed above half of the stirrer. 4. The stirring device according to claim 1, 2, or 3, wherein the sample contained in the test tube is blood.
JP57120596A 1982-07-13 1982-07-13 Stirring apparatus Granted JPS5912740A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP57120596A JPS5912740A (en) 1982-07-13 1982-07-13 Stirring apparatus
US06/511,947 US4518264A (en) 1982-07-13 1983-07-08 Stirring apparatus
EP83106806A EP0099103B1 (en) 1982-07-13 1983-07-11 Stirring apparatus
EP89113165A EP0344819A1 (en) 1982-07-13 1983-07-11 Automatic sample feed apparatus combined with or for feeding to a stirring apparatus
DE8383106806T DE3381981D1 (en) 1982-07-13 1983-07-11 MIXING DEVICE.
CA000432373A CA1245214A (en) 1982-07-13 1983-07-13 Apparatus for stirring and admixing a sample contained in a test tube to a homogeneously suspended state
CA000550021A CA1259048A (en) 1982-07-13 1987-10-22 Automatic sample storing and feed apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57120596A JPS5912740A (en) 1982-07-13 1982-07-13 Stirring apparatus

Publications (2)

Publication Number Publication Date
JPS5912740A JPS5912740A (en) 1984-01-23
JPH0530492B2 true JPH0530492B2 (en) 1993-05-10

Family

ID=14790168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57120596A Granted JPS5912740A (en) 1982-07-13 1982-07-13 Stirring apparatus

Country Status (1)

Country Link
JP (1) JPS5912740A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113546560A (en) * 2020-04-23 2021-10-26 长春市布拉泽医疗科技有限公司 Medical instrument test tube shakes even device

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0870211A (en) * 1994-08-30 1996-03-12 Harada Ind Co Ltd Antenna elevating/lowering device
JP4676330B2 (en) * 2005-12-28 2011-04-27 有限会社タック リサーチ Mixing device using swing fulcrum type lever device
FR2907905B1 (en) * 2006-10-30 2009-04-03 C2 Diagnostics Sa "APPARATUS AND METHOD FOR HANDLING TUBES, IN PARTICULAR AUTOMATIC BLOOD ANALYSIS APPARATUS"
CN105758698B (en) * 2016-05-09 2018-09-18 深圳市国赛生物技术有限公司 A kind of heparin tube rotary compacting device
CN110681296A (en) * 2019-11-06 2020-01-14 刘洁 Gastroenterology detects uses viewing device with oscillating mechanism

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950174A (en) * 1972-09-27 1974-05-15
JPS56161826A (en) * 1980-04-08 1981-12-12 Scient Mfg Ind Generator for vortex

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950174A (en) * 1972-09-27 1974-05-15
JPS56161826A (en) * 1980-04-08 1981-12-12 Scient Mfg Ind Generator for vortex

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113546560A (en) * 2020-04-23 2021-10-26 长春市布拉泽医疗科技有限公司 Medical instrument test tube shakes even device

Also Published As

Publication number Publication date
JPS5912740A (en) 1984-01-23

Similar Documents

Publication Publication Date Title
JP4491010B2 (en) Photometer
US3714815A (en) Means for simulating the natural flow of blood
JP4613164B2 (en) Whole blood hematology analyzer with stirrer
GB2081118A (en) Non-invasive mixing
JP4926854B2 (en) Platelet aggregation measurement method and platelet aggregation measurement apparatus
JPH0530492B2 (en)
JP2009025167A (en) Automatic analyzing apparatus
EP0542260A1 (en) Test strip automatic supply device and supply method using the same.
JPH0350451Y2 (en)
JPH0619359B2 (en) Liquid sample analyzer
US3789660A (en) Process, machine and chart for tensile testing
JPH0426434B2 (en)
CN220361076U (en) Oscillating device for pathogen rapid inspection
CN220345619U (en) Sample oscillation device
CN220559036U (en) Portable needle tube mixing instrument
CN220795151U (en) Quick titration device for drug inspection and analysis
KR101728711B1 (en) Mixing apparatus and method utilizing a capless tube
CN218726403U (en) Granularity testing device of nanometer zirconium dioxide
JPH0921815A (en) Automatic analyzing device
CN214225193U (en) Shake even device and protein analyzer
CN217542821U (en) Stepping type transmission mechanism for urine analyzer
JPS6326181Y2 (en)
JPH0384406A (en) Automatic traveling device for ultrasonic probe
RU44825U1 (en) MACHINE FOR TESTING MATERIALS FOR FRICTION AND WEARING
JP3704571B2 (en) Analysis equipment