JPH0314612A - Antimicrobial fiber - Google Patents
Antimicrobial fiberInfo
- Publication number
- JPH0314612A JPH0314612A JP16190A JP16190A JPH0314612A JP H0314612 A JPH0314612 A JP H0314612A JP 16190 A JP16190 A JP 16190A JP 16190 A JP16190 A JP 16190A JP H0314612 A JPH0314612 A JP H0314612A
- Authority
- JP
- Japan
- Prior art keywords
- antibacterial
- long
- acylamino acid
- fiber
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- LPUQAYUQRXPFSQ-DFWYDOINSA-M monosodium L-glutamate Chemical compound [Na+].[O-]C(=O)[C@@H](N)CCC(O)=O LPUQAYUQRXPFSQ-DFWYDOINSA-M 0.000 description 1
- 229940070800 myristoyl glutamate Drugs 0.000 description 1
- 125000002811 oleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 238000006068 polycondensation reaction Methods 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000874 polytetramethylene terephthalate Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- GUYXXEXGKVKXAW-UHFFFAOYSA-N prop-2-enenitrile Chemical compound C=CC#N.C=CC#N GUYXXEXGKVKXAW-UHFFFAOYSA-N 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- YPNVIBVEFVRZPJ-UHFFFAOYSA-L silver sulfate Chemical compound [Ag+].[Ag+].[O-]S([O-])(=O)=O YPNVIBVEFVRZPJ-UHFFFAOYSA-L 0.000 description 1
- 229910000367 silver sulfate Inorganic materials 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940071136 stearoyl glutamate Drugs 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 229920005992 thermoplastic resin Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 239000011882 ultra-fine particle Substances 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Landscapes
- Artificial Filaments (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
Abstract
Description
【発明の詳細な説明】
［技術分野］
本発明は種々の細菌およびカビ菌に対して抗菌効果を有
する抗菌性繊維に関する。DETAILED DESCRIPTION OF THE INVENTION [Technical Field] The present invention relates to antibacterial fibers having antibacterial effects against various bacteria and fungi.
［従来技術］
従来より、銀および銅が殺菌作用を有することは公知で
あり、例えば銀は硝酸銀等の水溶液の形態（Ａ ｇ”）
で消毒剤として広く利用されている。しかし，硝酸銀は
、水溶液の形態に限定され、溶液状のため取り扱いも不
便であり、従って用途の点でも限定されるという欠点が
あった。[Prior Art] It has been known that silver and copper have a bactericidal effect. For example, silver can be used in the form of an aqueous solution such as silver nitrate (A g").
It is widely used as a disinfectant. However, silver nitrate has the disadvantage that it is limited to the form of an aqueous solution, which makes it inconvenient to handle and therefore limits its uses.
また、銀やそれの化合物を活性炭、アルミナ、シリカゲ
ル、ゼオライト等の吸着物質に吸着させて殺菌目的に利
用することも知られている。It is also known that silver and its compounds can be adsorbed onto adsorbent materials such as activated carbon, alumina, silica gel, and zeolite for sterilization purposes.
上記のようなものとして、特開昭６２−２４１９３９号
公報、特開昭６２−２３８９００号公報に示されるもの
があり、ζれらは、殺菌作用を有する金属をイオン状態
で保持しているゼオライトを含有するポリオレフィン樹
脂戊形体および紙である。Examples of the above-mentioned materials include those shown in JP-A No. 62-241939 and JP-A No. 62-238900. These are polyolefin resin rods and paper containing.
また、特開昭６２−７０２２１号公報に示されるものと
して、式
Ｍ ｔ Ｏ ” Ａ Ｑ ｔ Ｏ ３・Ｓｉｎｔ（式中
Ｍは銀など）で表わされた抗菌および／または殺菌作用
を有する無定形アルミノ珪酸塩がある。Furthermore, as shown in Japanese Patent Application Laid-Open No. 62-70221, a compound having an antibacterial and/or bactericidal effect represented by the formula M t O ” A Q t O 3 · Sint (where M is silver, etc.) There are regular aluminosilicates.
［先行技術の問題点］
しかし、上述の硝酸銀は、水溶液の形態に限定されるた
め、繊維に直接添加することが困難であり、また、硝酸
銀は水溶性のため、水に接触すると溶出しやすく、長期
的な抗菌効果を期待できるものではない。[Problems with the prior art] However, since the silver nitrate mentioned above is limited to the form of an aqueous solution, it is difficult to add it directly to fibers, and since silver nitrate is water-soluble, it easily dissolves when it comes into contact with water. However, long-term antibacterial effects cannot be expected.
また、上記のゼオライトなどに銀を吸着させたものでは
、使用されている殺菌性を有する金属が、イオン化しや
すく、このため、液体物などに接触したとき、流出しや
すく、安全性に問題があり、また、ゼオライトなどは無
機材料であるため、繊維を形成する材質との親和性が低
く、繊維の物性を低下させる可能性がある。In addition, in the above-mentioned zeolite, etc., in which silver is adsorbed, the sterilizing metal used tends to ionize, and therefore, when it comes into contact with liquids, it tends to leak out, which poses safety problems. Moreover, since zeolite and the like are inorganic materials, they have low affinity with the material forming the fibers and may deteriorate the physical properties of the fibers.
そこで、本発明は、上記の従来技術の問題点を解決し、
高い抗菌性、殺菌性を有するとともに、安全性が高く、
さらに、繊維の物性の低下がない抗菌性合或繊維を提供
するものである。Therefore, the present invention solves the above-mentioned problems of the prior art, and
It has high antibacterial and bactericidal properties, and is highly safe.
Furthermore, the present invention provides antibacterial synthetic fibers that do not cause deterioration in the physical properties of the fibers.
［問題点を解決するための手段］
上記目的を達戊するものは、抗菌作用を有する金属のＮ
一長鎖アシルアミノ酸塩を含有する抗菌性繊維である。[Means for solving the problem] What achieves the above purpose is the use of N, a metal with antibacterial activity.
Antibacterial fiber containing long-chain acylamino acid salt.
そして、前記Ｎ一長鎖アシルアミノ酸塩の・、アシル基
が、ステアロイル基、ラウロイル基、ミリストイル基、
パルミトイル基のいずれかであることが好ましい。さら
に、前記抗菌作用を有する金属は、銀、銅、鉛、亜鉛、
錫からなる群から選ばれたいずれか１つであることが好
ましい。The acyl group of the N long-chain acylamino acid salt is a stearoyl group, a lauroyl group, a myristoyl group,
Any palmitoyl group is preferred. Furthermore, the metals having antibacterial effects include silver, copper, lead, zinc,
Preferably, it is one selected from the group consisting of tin.
そこで、本発明の抗菌性繊維を実施例を用いて説明する
。Therefore, the antibacterial fiber of the present invention will be explained using Examples.
本発明の抗菌性繊維は、抗菌作用を有する金属のＮ一長
鎖アシルアミノ酸塩（以下、「Ｎ−長鎖アシルアミノ酸
抗菌性金属塩」）を含有している。The antibacterial fiber of the present invention contains an N-long chain acylamino acid salt of a metal having an antibacterial effect (hereinafter referred to as "N-long chain acylamino acid antibacterial metal salt").
本発明の抗菌性繊維に使用されるＮ一長鎖アシルアミノ
酸抗菌性金属塩は、抗菌作用を有する金属とＮ一長鎖ア
シルアミノ酸との塩である。The N long-chain acylamino acid antibacterial metal salt used in the antibacterial fiber of the present invention is a salt of a metal having an antibacterial effect and an N long-chain acylamino acid.
本発明に使用されるＮ一長鎖アシルアミノ酸抗菌性金属
塩の形或に用いられる抗菌作用を有する金属としては、
銀、銅、鉛、亜鉛、錫などが好適に使用できる。また、
金属は１種類に限らず複数の種類の金属を用いてもよい
。そして、上記金属のうち、抗菌力、安全性の点より、
銀または銅がより好適であり、抗菌力の点から、特に好
ましくは、銀である。The antibacterial metals used in the form of N long-chain acylamino acid antibacterial metal salts used in the present invention include:
Silver, copper, lead, zinc, tin, etc. can be suitably used. Also,
The metal is not limited to one type, and multiple types of metals may be used. Among the above metals, from the viewpoint of antibacterial power and safety,
Silver or copper is more preferred, and from the standpoint of antibacterial activity, silver is particularly preferred.
本発明に使用されるＮ一長鎖アシルアミノ酸抗菌性金属
塩の形或に用いられるＮ一長鎖アシルアミノ酸は、Ｎ位
に長鎖アシル基（脂肪酸残基）を有するアミノ酸である
。The N long-chain acylamino acid used in the form of the antibacterial metal salt of the N long-chain acylamino acid used in the present invention is an amino acid having a long-chain acyl group (fatty acid residue) at the N-position.
長鎖アシル基としては、塩を形成する金属の酸化を防止
するために、光、特に紫外線に対する安定性の高いもの
が好ましい。上記のようなものとしては、高級脂肪酸残
基が好ましく、例えばデカメイル基、ラウロイル基、ミ
リストイル基、パルミトイル基、ステアロイル基、オレ
オイル基などが好ましい。The long-chain acyl group is preferably one that is highly stable to light, especially ultraviolet light, in order to prevent oxidation of the metal forming the salt. As the above-mentioned ones, higher fatty acid residues are preferable, such as decamyl group, lauroyl group, myristoyl group, palmitoyl group, stearoyl group, oleoyl group, etc.
特に、光に対する安定性の点よりステアロイル基が好ま
しい。またアシル基としては、単一のものに限られず、
上記のアシル基の複数の種類のものを用いてもよい。In particular, a stearoyl group is preferred from the viewpoint of stability against light. Furthermore, the acyl group is not limited to a single one,
Multiple types of the above-mentioned acyl groups may be used.
このＮ一長鎖アシルアミノ酸抗菌性金属塩の光に対する
安定性の理由は明確ではないが、長鎖アシル基（脂肪酸
残基）の長鎖アルキル基が紫外線をある程度吸収するも
のと予想される。Although the reason for the stability against light of this N long-chain acylamino acid antibacterial metal salt is not clear, it is expected that the long-chain alkyl group of the long-chain acyl group (fatty acid residue) absorbs ultraviolet rays to some extent.
アミノ酸としては、モノアミノモノカルボン酸、モノア
ミノジカルボン酸、ジアミノモノカルボン酸のいずれで
もよい。Ｎ一長鎖アシルアミノ酸抗菌性金属塩として、
高い抗菌性を有するものとする場合には、モノアミノジ
カルボン酸を用いることが好ましく、このモノアミノジ
カルボン酸は、２つのカルボキシル基を有するので、抗
菌作用を有する金属が結合しやすく、全体として抗菌作
用の強いものとすることができる。本発明の抗菌性繊維
としては、アミノ酸に１つの抗菌作用を有する金属が結
合した塩を用いれば十分な抗菌力を有する。The amino acid may be monoaminomonocarboxylic acid, monoaminodicarboxylic acid, or diaminomonocarboxylic acid. As an antibacterial metal salt of N long-chain acylamino acid,
In order to have high antibacterial properties, it is preferable to use monoaminodicarboxylic acid.Since this monoaminodicarboxylic acid has two carboxyl groups, it is easy for metals that have antibacterial activity to bind to it, so that it has antibacterial properties as a whole. It can be made to have a strong effect. The antibacterial fiber of the present invention has sufficient antibacterial activity if a salt in which one metal having an antibacterial action is bonded to an amino acid is used.
アミノ酸の具体例としては、モノアミノモノカルボン酸
としては、グリシン、アラニン、パリン、ロイシン、フ
ェニルアラニン、チロシン、トレオニン、トリブトファ
ン、メチオニンなどであり、モノアミノジカルボン酸と
しては、アスパラギン酸、グルタミン酸であり、ジアミ
ノモノカルボン酸としては、リジン、アルギニン、ヒス
チジンである。Specific examples of amino acids include monoaminomonocarboxylic acids such as glycine, alanine, parine, leucine, phenylalanine, tyrosine, threonine, tributophane, and methionine, and monoaminodicarboxylic acids such as aspartic acid and glutamic acid. Diaminomonocarboxylic acids include lysine, arginine, and histidine.
よって、本発明の抗菌性繊維に使用されるＮ−長鎖アシ
ルアミノ酸抗菌性金属塩の好ましい具体例としては、Ｎ
−ステアロイルグルタミン酸銀、Ｎ−ラウロイルグルタ
ミン酸銀、Ｎ−ミリストイルグルタミン酸銀、Ｎ−ステ
アロイルアスハラギンｆ［ｌ、Ｎ−ラウロイルアスパラ
ギン酸銀、Ｎ一ミリストイルアスパラギン酸銀、Ｎ−ス
テアロイルグルタミン酸銅、Ｎ−ラウロイルグルタミン
酸銅、Ｎ一ミリストイルグルタミン酸銅、Ｎ−ステアロ
イルアスパラギン酸銅、Ｎ−ラウロイルアスパラギン酸
銅、Ｎ一ミリストイルアスパラギン酸銅、Ｎ−ステアロ
イルバリン銀、Ｎ−ラウロイルバリン銀、Ｎ一ミリスト
イルハリン銀、Ｎ−ステアロイルバリン銅、Ｎ−ラウロ
イルバリン銅、Ｎ−ミリストイルバリン銅、Ｎ−ステア
ロイルフェニルアラニン銀、Ｎ−ラウロイルフェニルア
ラニン銀、Ｎ−ミリストイルフェニルアラニン１、Ｎ−
ステアロイルフエニルアラニン銅、Ｎ−ラウロイルフェ
ニルアラニン銅、Ｎ−ミリストイルフエニルアラニンｌ
、Ｎ−ステアロイルアルギニンｆｆｌ、Ｎ−ラウロイル
アルギニン銀、Ｎ一ミリストイルアルギニン銀、Ｎ−ス
テアロイルアルギニン銅、Ｎ−ラウロイルアルギニン銅
、Ｎ−ミリストイルアルギニン銅などである。Therefore, as a preferred specific example of the N-long chain acylamino acid antibacterial metal salt used in the antibacterial fiber of the present invention, N
- Silver stearoyl glutamate, Silver N-lauroyl glutamate, Silver N-myristoyl glutamate, N-stearoyl asharagine f[l, Silver N-lauroyl aspartate, Silver N-myristoyl aspartate, Copper N-stearoyl glutamate, N-Lauroyl glutamate Copper, N-myristoyl copper glutamate, N-copper stearoyl aspartate, N-copper lauroyl aspartate, N-myristoyl copper aspartate, N-stearoyl valine silver, N-lauroyl valine silver, N-myristoyl haline silver, N-stearoyl Copper valine, copper N-lauroylvaline, copper N-myristoylvaline, silver N-stearoylphenylalanine, silver N-lauroylphenylalanine, N-myristoylphenylalanine 1, N-
Stearoylphenylalanine copper, N-lauroylphenylalanine copper, N-myristoylphenylalanine l
, N-stearoyl arginine ffl, N-lauroyl arginine silver, N-myristoyl arginine silver, N-stearoyl arginine copper, N-lauroyl arginine copper, N-myristoyl arginine copper, and the like.
そして、上記の、Ｎ一長鎖アシルアミノ酸抗菌性金属塩
は、水、各種の有機溶媒に対して難溶であり、常温にお
いて粉末状であり、合戊樹脂に容易に混練することがで
き、よって、各種の紡糸原液に添加することができる。The above-mentioned N long-chain acylamino acid antibacterial metal salt is sparingly soluble in water and various organic solvents, is in powder form at room temperature, and can be easily kneaded into synthetic resin. Therefore, it can be added to various spinning dope solutions.
そして、本発明の抗菌性′ａ維に使用されるＮ一長鎖ア
シルアミノ酸抗菌性金属塩は、以下のようにして、形戊
することができる。The N long-chain acylamino acid antibacterial metal salt used in the antibacterial fiber of the present invention can be shaped as follows.
まｆ、Ｎ−４ｊＪｌアシルアミノ酸のナトリウム、カリ
ウムなどのアルカリ金属塩の水溶液に、抗菌性を有する
金属の塩、例えば硝酸銀、硝酸銅、硫酸銀、塩化銅、硫
酸銅などの水溶性の塩の水溶液を混合することにより、
Ｎ一長鎖アシルアミノ酸抗菌性金属塩を沈澱物として容
易に得ることができる。そして、上記のように得たＮ一
長鎖アシルアミノ酸抗菌性金属塩の沈澱物を、乾燥（例
えば、加熱乾燥、凍結乾燥）させることにより、粉末状
のＮ一長鎖アシルアミノ酸抗菌性金属塩を得ることがで
きる。Maf, N-4jJl A water-soluble salt of a metal having antibacterial properties, such as silver nitrate, copper nitrate, silver sulfate, copper chloride, copper sulfate, etc., is added to an aqueous solution of an alkali metal salt such as sodium or potassium of an acylamino acid. By mixing aqueous solutions,
N long-chain acylamino acid antibacterial metal salt can be easily obtained as a precipitate. The precipitate of the N long-chain acylamino acid antibacterial metal salt obtained as described above is then dried (e.g., heat drying, freeze-drying) to form a powdery N long-chain acylamino acid antibacterial metal salt. can be obtained.
そして、このＮ一長鎖アシルアミノ酸抗菌性金属塩は、
粉末状となっており、各分子中に少なくとも１つの抗菌
性を有する金属が結合した塩であるので、極めて高い抗
菌力を有している。This N long-chain acylamino acid antibacterial metal salt is
It is in the form of a powder, and since it is a salt with at least one antibacterial metal bound to each molecule, it has extremely high antibacterial activity.
さらに、このＮ一長鎖アシルアミノ酸抗菌性金属塩は、
基本骨格を形戊するものがアミノ酸であるため、毒性が
極めて少なく、種々の用途に安全に使用できる。さらに
、Ｎ一長鎖アシルアミノ酸抗菌性金属塩は、長鎖アシル
基を有する安定した状態のものを用いたたため、Ｎ一長
鎖アシルアミノ酸抗菌性金属塩を形戊している金属が光
、とくに紫外線により酸化されることが少なく、繊維の
変色を抑制する。さらに、Ｎ−長鎖アシルアミノ酸抗菌
性金属塩という安定した状態となっているので、塩を形
戊する金属のみが流出しに＜＜、安全であり、繊維中に
に混入させることができる。Furthermore, this N long-chain acylamino acid antibacterial metal salt is
Since the basic skeleton is made of amino acids, it has extremely low toxicity and can be safely used for various purposes. Furthermore, since the N long-chain acylamino acid antibacterial metal salt was in a stable state and had a long-chain acyl group, the metal forming the N long-chain acylamino acid antibacterial metal salt was exposed to light. In particular, it is less likely to be oxidized by ultraviolet rays and suppresses discoloration of fibers. Furthermore, since the N-long chain acylamino acid antibacterial metal salt is in a stable state, only the metal forming the salt is safe from leaching out and can be mixed into the fiber.
そして、上記のＮ一長鎖アシルアミノ酸抗菌性金属塩を
繊維材料への分散性を向上させるために、微粒子を屁合
させてもよい。微粒子としては、その安定性、分散性、
微粒子の形状、粒径の均一性、超微粒子を得られること
より、セラミックス微粒子、チタニウム微粉末が好まし
い。セラミックス微粒子としては、シリカ微粒子、アル
ミナ微粒子、ジルコニア微粒子、ゼオライト微粒子など
が好適に使用できる。特に、好ましくは、シリカ微粒子
である。そして、微粒子の粒径としては、ｌμ次以下程
度、好ましくは、１〜０．Ｏｌμｌが好ましい。微粒子
とＮ−長鎖アシルアミノ酸抗菌性金属塩との混合比は、
抗菌性の要求されるレベルが高いほど、Ｎ一長鎖アシル
アミノ酸抗菌性金属塩の含有量が多くなる。一般的に、
微粒子とＮ一長鎖アシルアミノ酸抗菌性金属塩と屁合比
は、重量比で１０００：１〜１：ｌ程度が好ましい。Then, in order to improve the dispersibility of the above-mentioned N long-chain acylamino acid antibacterial metal salt into the fiber material, fine particles may be combined. As fine particles, their stability, dispersibility,
Ceramic fine particles and titanium fine powder are preferred because of the uniformity of fine particle shape and particle size and the ability to obtain ultrafine particles. As the ceramic fine particles, silica fine particles, alumina fine particles, zirconia fine particles, zeolite fine particles, etc. can be suitably used. Particularly preferred are silica fine particles. The particle size of the fine particles is approximately 1μ or less, preferably 1 to 0. Olμl is preferred. The mixing ratio of fine particles and N-long chain acylamino acid antibacterial metal salt is:
The higher the level of antibacterial properties required, the higher the content of the N long-chain acylamino acid antibacterial metal salt. Typically,
The weight ratio of the fine particles to the N long-chain acylamino acid antibacterial metal salt is preferably about 1000:1 to 1:l.
そして、本発明の抗菌性繊維は、繊維を形戊する材料中
に、上述のＮ一長鎖アシルアミノ酸抗菌性金属塩が含有
されている。含有されてぃるＮ一長鎖アシルアミノ酸抗
菌性金属塩は、光に対して安定であるため、使用時ある
いは保存時に繊維の表面が、含有された抗菌作用性物質
の原因による変色を起こすことがない。そして、アシル
基が有するアルキル基により含有されるＮ一長鎖アシル
アミノ酸抗菌性金属塩は、繊維の材料が有機物であれば
、その材料となしみやすいため、無機物を入れた場合に
比べ、繊維材料の物性の低下が少ないという利点も有し
ている。抗菌性繊維は、種々のものに利用でき、例えば
、織布として、衣料品（例えば、靴下）、シーツ、フィ
ルター材料、不織布として、フィルター材料、包装材料
などが考えられる。The antibacterial fiber of the present invention contains the above-mentioned N long-chain acylamino acid antibacterial metal salt in the material forming the fiber. The N long-chain acylamino acid antibacterial metal salt contained in the fiber is stable against light, so the surface of the fiber may discolor during use or storage due to the contained antibacterial substance. There is no. The N long-chain acylamino acid antibacterial metal salt contained in the alkyl group of the acyl group is more likely to penetrate into the fiber material if it is an organic material. It also has the advantage that there is little deterioration in physical properties. Antibacterial fibers can be used for various purposes, such as woven fabrics for clothing (eg, socks), sheets, filter materials, non-woven fabrics for filter materials, packaging materials, and the like.
また、繊維を形成するための材料としては、繊維を形或
できる材料であればいかなるものでも使用可能であり、
例えば、ポリオレフィン樹脂（例えば、ポリプロピレン
、ポリエチレン）、ボリアミド、ポリエステル、アクリ
ロニトリル、再生セルロース（例えば、酢酸セルロース
、銅アンモニアセルロース）などの合成繊維、さらには
毛、麻、絹、木綿などの天然繊維などが使用される。Furthermore, any material that can be used to form fibers can be used as the material for forming the fibers.
For example, synthetic fibers such as polyolefin resins (e.g., polypropylene, polyethylene), polyamide, polyester, acrylonitrile, regenerated cellulose (e.g., cellulose acetate, cuprammonium cellulose), as well as natural fibers such as wool, hemp, silk, and cotton. used.
そして、本発明の抗菌性繊維中のＮ一長鎖アシルアミノ
酸抗菌性金属塩の含有量としては、０．０５％以上、好
ましくはｏｏ１％以上であれば、十分な抗菌作用を発現
できる。含有量の範囲としては、０．１〜０．５％程度
がより好適である。When the content of the N long-chain acylamino acid antibacterial metal salt in the antibacterial fiber of the present invention is 0.05% or more, preferably oo1% or more, a sufficient antibacterial effect can be exhibited. The content range is more preferably about 0.1 to 0.5%.
そして、抗菌性繊維は、例えば、繊維が熱可塑性樹脂（
例えば、ポリプロピレン、ポリエチレン、ポリエステル
）を用いるものであれば、あらかじめ樹脂中にＮ一長鎖
アシルアミノ酸抗菌性金属塩を含有したべレフトを作戊
し、その抗菌作用性物質を含有した樹脂を必要な形状を
した口金装置より押し出すことにより作成される。Antibacterial fibers, for example, are made of thermoplastic resin (
For example, if a material (such as polypropylene, polyethylene, or polyester) is used, a beleft containing an N long-chain acylamino acid antibacterial metal salt is prepared in advance, and a resin containing the antibacterial substance is required. It is created by extruding it from a cap device with a different shape.
また、繊維が、セルロースのような再生繊維の場合にお
いては、紡糸原液中にＮ−アシルアミノ酸抗菌性金属塩
を分散させたものを、必要な形状をした口金装置より押
し出し、凝固、再生させることにより作戊できる。In addition, when the fiber is a regenerated fiber such as cellulose, N-acyl amino acid antibacterial metal salt dispersed in the spinning dope is extruded through a die device having the necessary shape, coagulated, and regenerated. It can be made by
そして、合戊繊維では、一般的に、分子配向、結晶化度
を高めるため、さらに繊維径の調整、物性特に強度を向
上させるために、繊維材料の二次転移点以上の温度で、
数倍（具体的には、２〜１０倍程度）に延伸される。さ
らに、繊維の寸法安定性のために、必要に応じて熱処理
が行われる。特に、本発明の抗菌性繊維は、この延伸を
行うことが好ましく、この延伸が行われることにより、
繊維中に含有されているＮ一長鎖アシルアミノ酸抗菌性
金属塩は、繊維の延伸にともない、繊維材料である合戊
樹脂との親和性の高い部分であるＮ一長鎖アシル基部分
は、繊維材料中にとりこまれた状態でこの部分を軸とし
て、繊維材料と親和性の低い抗菌性金属部分が起き上が
るため、繊維材料の表面付近に位置していた抗菌性金属
が起き上がり、表面に露出しやすくなる。このため、よ
り高い抗菌作用を発現する。In order to improve molecular orientation and crystallinity, as well as to adjust fiber diameter and improve physical properties, especially strength, synthetic fibers are generally heated at temperatures above the secondary transition point of the fiber material.
It is stretched several times (specifically, about 2 to 10 times). Furthermore, heat treatment is performed as necessary for the dimensional stability of the fibers. In particular, the antibacterial fiber of the present invention is preferably subjected to this stretching, and by performing this stretching,
As the N long-chain acylamino acid antibacterial metal salt contained in the fiber is drawn, the N long-chain acyl group moiety, which has a high affinity with the synthetic resin that is the fiber material, The antibacterial metal part that has low affinity with the fiber material rises around this part while it is incorporated into the fiber material, so the antibacterial metal that was located near the surface of the fiber material rises and is exposed to the surface. It becomes easier. Therefore, it exhibits a higher antibacterial effect.
次に、本発明の抗菌性繊維の具体例として、ポリエステ
ルを用いた本発明の抗菌性合成繊維について説明する。Next, as a specific example of the antibacterial fiber of the invention, an antibacterial synthetic fiber of the invention using polyester will be described.
ポリエステルとしては、繊維に成形し得るポリエステル
を主体とするものであればどのようなものでもよく、例
えば、ポリエチレンテレフタレート、ポリ−１．４−シ
クロヘキシレンジメチレンテレフタレート、ポリテトラ
メチレンテレフタレート、ポリエチレン２．６−ナフタ
リンジカルボキシレート、ポリエチレンーα，β−ビス
（２−クロルフェノキシ）エタン−４，４゜−ジカルボ
キシレート等が挙げられるが、ポリエステル製造工程で
添加する無機微粒子の凝集を促進させない程度に主戊分
以外を二官能性カルボン酸戊分で置き換えたポリエステ
ルであってもよく、またエチレングリコールおよびブタ
ンジオールなどのグリコール戊分以外に他のジオール或
分で置き換えたポリエステルであってもよい。更に、各
種添加剤、たとえば易染剤、無燃剤、制電剤、親水剤等
を必要に応して共重合または混合したポリエステルであ
ってもよい。The polyester may be any polyester that can be formed into fibers, such as polyethylene terephthalate, poly-1,4-cyclohexylene dimethylene terephthalate, polytetramethylene terephthalate, polyethylene 2. Examples include 6-naphthalene dicarboxylate, polyethylene-α,β-bis(2-chlorophenoxy)ethane-4,4°-dicarboxylate, but to the extent that they do not promote aggregation of inorganic fine particles added in the polyester manufacturing process. It may be a polyester in which components other than the main component are replaced with a difunctional carboxylic acid component, or a polyester in which the glycol component such as ethylene glycol and butanediol is replaced with another diol component. . Furthermore, the polyester may be copolymerized or mixed with various additives, such as a dye-facilitating agent, a flameless agent, an antistatic agent, a hydrophilic agent, etc., as required.
次に、ポリエステル繊維の製造方法の一例を説明するが
、この方法に限定されるものではない。Next, an example of a method for manufacturing polyester fiber will be described, but the method is not limited to this method.
まず、平均の一次粒子径が１００μｌ以下、好ましくは
、５０μ貢以下の上記Ｎ一長鎖アシルアミノ酸抗菌性金
属塩を、このＮ一長鎖アシルアミノ酸抗菌性金属塩の平
均一次粒子径より十分大きい径を有し、かつ平均粒子径
が０． ５ｘｍ以下の上述の粒子とともに撹拌ししかる
のち粒子を分離して得た無機粒子スラリーを、ポリエス
テルの製造反応系に添加して得た凝集粗大粒子の少ない
ポリエステルを５００１）１１７ｍｉｎ以上の紡糸速度
で超高速紡糸することにより、本発明の抗菌性繊維が得
られる。First, the above-mentioned N long-chain acylamino acid antibacterial metal salt having an average primary particle size of 100 μl or less, preferably 50 μl or less is added, which is sufficiently larger than the average primary particle size of the N long-chain acylamino acid antibacterial metal salt. diameter, and the average particle diameter is 0. The inorganic particle slurry obtained by stirring with the above-mentioned particles of 5 x m or less and then separating the particles is added to the reaction system for producing polyester to obtain a polyester with few aggregated coarse particles. The antibacterial fiber of the present invention can be obtained by high-speed spinning.
次に、本発明の抗菌性繊維として、アクリロニトリルを
用いた抗菌性繊維について説明する。Next, as the antibacterial fiber of the present invention, an antibacterial fiber using acrylonitrile will be explained.
繊維基材としては、アクリロニトリル３０〜７０重量％
を主戊分とするアクリロニトリル系共重合が好適である
。より具体的には、アクリロニトリルー塩化ビニル共重
合体、アクリロニトリル− 塩化１：’ニリデン共重合
体、アクリロニトリルー塩化ビニルー塩化ビニリデン共
重合体、アクリロニトリルー臭化ビニル共重合体、アク
リ口ニトリルー塩化ピニリデンー臭化ビニル共重合体、
アクリロニトリルー塩化ビニルー臭化ビニル共重合体等
である。また、繊維基剤はアクリロニトリルとして少な
くとも１種以上のハロゲン含有単量体の他に、これらと
共重合可能なオレフィン系単量体をｌＯ重量％以下含有
してもよい。共重合可能なオレフィン系単量体としては
、アクリル酸およびそのエステル、メタクリル酸および
そのエステル、アクリルアミド、メタクリルアミド、酢
酸ビニル、ピニルスルフォン酸およびその塩、メタクリ
ルスルフォン酸およびその塩、スチレンスルフォン酸お
よびその塩などをあげることが出来る。そして、Ｎ一長
鎖アシルアミノ酸抗菌性金属塩が繊維基材に添加された
繊維の紡糸方法としては、従来の紡糸方広を用いて行う
ことができる。As the fiber base material, 30 to 70% by weight of acrylonitrile
Acrylonitrile-based copolymerization containing as the main component is preferred. More specifically, acrylonitrile-vinyl chloride copolymer, acrylonitrile-1:'nylidene chloride copolymer, acrylonitrile-vinyl chloride-vinylidene chloride copolymer, acrylonitrile-vinyl bromide copolymer, acrylonitrile-pinylidene chloride-odor vinyl chloride copolymer,
These include acrylonitrile-vinyl chloride-vinyl bromide copolymer. In addition to at least one halogen-containing monomer as acrylonitrile, the fiber base may also contain 10% by weight or less of an olefinic monomer copolymerizable with these monomers. Copolymerizable olefinic monomers include acrylic acid and its esters, methacrylic acid and its esters, acrylamide, methacrylamide, vinyl acetate, pinylsulfonic acid and its salts, methacrylsulfonic acid and its salts, styrenesulfonic acid and its salt, etc. The fiber in which the N long-chain acylamino acid antibacterial metal salt is added to the fiber base material can be spun using a conventional spinning method.
そして、作或された抗菌性合成繊維を用いてフィルター
、通気性包装材料を形或する場合には、上記のようなＮ
一長鎖アシルアミノ酸抗菌性金属塩を含有した熱可塑性
合成繊維（例えば、ポリエチレン）を用いて不織布を作
戊することにより、通気性、抗菌性かつ撥水性を有し、
光りに対して安定なフィルター材料、包装材料を形戊す
ることができる。When forming filters and breathable packaging materials using the created antibacterial synthetic fibers, the above-mentioned N
By making a nonwoven fabric using thermoplastic synthetic fibers (e.g., polyethylene) containing long-chain acylamino acid antibacterial metal salts, it has breathability, antibacterial properties, and water repellency.
Filter materials and packaging materials that are stable against light can be formed.
また、抗菌性繊維としては、上記のＮ一長鎖アノルアミ
ノ酸抗菌性金属塩を含有しておればよく、上記のような
繊維材料中に含有されているものに限らず、繊維の表面
にＮ一長鎖アシルアミノ酸抗菌性金属塩がを付着したも
のであってモヨい。繊維の表面にＮ一長鎖アシルアミノ
酸抗菌性金属塩を付着させる方法としては、繊維の表面
に対して付着性を有する物質中にＮ一長鎖アシルアミノ
酸抗菌性金属塩を含有させ、この物質（液状）を繊維の
表面に塗布することにより行うことができる。そのよう
な方法とじては、例えば、水性系の場合として、粘着性
を有するセルロース系物質、例えば、カルボキシメチル
セルロース；メチルセルロース、オキシプロビルセルロ
ース、オキシェチルセルロース、また、ＰＶＡ （ポリ
ビニルアルコール）、Ｐｖｐ（ポリビニルピロリドン）
、ビニルピロリドンー酢酸ビニル共重合体などの水溶液
中にＮ−長鎖アシルアミノ酸抗菌性金属塩を含有させた
ものを繊維の表面に塗布し乾燥させることにより作或さ
．れる。また、疎水性樹脂系の場合としては、ンリフー
ン樹脂系コーティング剤（例えば、ジメチルシロキサン
系コーティング剤、メチルハイドロジエンポリシロキサ
ン系コーティング剤、メチルトリクロロシロキサン系コ
ーティング剤、シランカップリン剤）、またフッ素樹脂
系コーティング剤中にＮ一長鎖アシルアミノ酸抗菌性金
属塩を含有させたものを繊維の表面に塗布し乾燥させる
ことにより作戊される。In addition, the antibacterial fibers only need to contain the above-mentioned N long-chain anol amino acid antibacterial metal salts, and are not limited to those contained in the above-mentioned fiber materials. N long-chain acylamino acid with antibacterial metal salt attached, so it's flimsy. As a method for attaching an antibacterial metal salt of N long-chain acylamino acid to the surface of fibers, the antibacterial metal salt of N long-chain acylamino acid is contained in a substance that is adhesive to the surface of fibers, and this substance is This can be done by applying (liquid) to the surface of the fiber. Such methods include, for example, in the case of aqueous systems, adhesive cellulosic substances such as carboxymethyl cellulose; methyl cellulose, oxypropyl cellulose, oxyethyl cellulose, PVA (polyvinyl alcohol), Pvp (Polyvinylpyrrolidone)
It is produced by applying an antibacterial metal salt of N-long chain acylamino acid in an aqueous solution such as vinylpyrrolidone-vinyl acetate copolymer to the surface of the fiber and drying it. It will be done. In addition, in the case of hydrophobic resins, there are also non-resin-based coating agents (e.g., dimethylsiloxane-based coating agents, methylhydrodiene polysiloxane-based coating agents, methyltrichlorosiloxane-based coating agents, silane coupling agents), and fluororesin-based coating agents. It is produced by applying a coating agent containing an antibacterial metal salt of N long-chain acylamino acid to the surface of the fiber and drying it.
［実施例］ 次に、本発明の抗菌性繊維の具体的実施例を説明する。[Example] Next, specific examples of the antibacterial fiber of the present invention will be described.
（製造例１）
Ｎ一長鎖アシルアミノ酸のアルカリ金属塩として、Ｎ−
ステアロイルーＬ−グルタミン酸ジナトリウム（味の素
株式会社製、商品名アミソフトＩｓ−２１）を用い、水
１０００ｃｃに、Ｎ−ステアロイルーＬ−グルタミン酸
ジナトリウムを２７９を溶解した水溶液を作戊した。抗
菌性を有する金属として、銀を用い、硝酸銀１６９を水
１０００ｃｃに溶解した硝酸銀水溶液を作戊した。そし
て、上記のＮ−ステアロイルーし−グルタミン酸ジナト
リウム水溶液に、上記の硝酸銀水溶液を混合させること
により、沈澱物が形成され、この沈澱物を加熱乾燥させ
てＮ−ステアロイルーＬ−グルタミン酸銀約３７９得た
。(Production Example 1) As an alkali metal salt of N long-chain acylamino acid, N-
Using disodium stearoyl L-glutamate (manufactured by Ajinomoto Co., Inc., trade name Amisoft Is-21), an aqueous solution was prepared by dissolving 279 of disodium N-stearoyl L-glutamate in 1000 cc of water. Using silver as a metal having antibacterial properties, a silver nitrate aqueous solution was prepared by dissolving 169 silver nitrate in 1000 cc of water. Then, by mixing the above aqueous silver nitrate solution with the aqueous solution of disodium N-stearoyl-glutamate, a precipitate was formed, and this precipitate was dried by heating to obtain about 379 g of silver N-stearoyl-L-glutamate. .
（製造例２）
Ｎ−ステアロイルーし−グルタミン酸モノナトリウム（
味の素株式会社製、商品名アミソフ｝ ＨＳ−１１）を
水１０００ｃｃに、２５９を溶解した水溶液を作或した
。硝酸銀１６９を水ＩＱＯＧｃｃに溶解した硝酸銀水溶
液を作成した。そして、上記のＮ−ステアロイルーＬ−
グルタミン酸モノナトリウム水溶液に、上記の硝酸銀水
溶液を混合させることにより、沈澱物が形戊され、この
沈澱物を加熱乾燥させてＮ−ステアロイルーし−グルタ
ミン酸銀約３６９得た。(Production Example 2) N-stearoyl monosodium glutamate (
An aqueous solution was prepared by dissolving 259 (manufactured by Ajinomoto Co., Inc., trade name: Amisof HS-11) in 1000 cc of water. A silver nitrate aqueous solution was prepared by dissolving silver nitrate 169 in water IQOGcc. And the above N-stearoyl L-
A precipitate was formed by mixing the above silver nitrate aqueous solution with an aqueous monosodium glutamate solution, and this precipitate was dried by heating to obtain about 369 g of N-stearoyl-silver glutamate.
（製造例３〉
Ｎ−ステアロイルーＬ−グルタミン酸ジナトリウム（味
の素株式会社製、商品名アミソフト＋１３−２１）を水
１０００ｃｃに、８３ｇを溶解した水溶液を作戊した。(Production Example 3) An aqueous solution was prepared by dissolving 83 g of disodium N-stearoyl-L-glutamate (manufactured by Ajinomoto Co., Inc., trade name Amisoft +13-21) in 1000 cc of water.
抗菌性を有する金属として、銅を用い、硝酸銅３’ｌｌ
を水１０ＱＯｃｃに溶解した硝酸銅水溶液を作戊した。Copper is used as a metal with antibacterial properties, and 3'll of copper nitrate is used.
A copper nitrate aqueous solution was prepared by dissolving the above in 10QOcc of water.
そして、上記のＮ−ステアロイルーし−グルタミン酸
ジナトリウム水溶液に、上記の硝酸銅水溶液を混合させ
ることにより、沈澱物が形戊され、この沈澱物を加熱乾
燥させてＮ−ステアロイルーＬ−グルタミン酸銅約９３
１？得た。Then, by mixing the above aqueous copper nitrate solution with the above aqueous solution of disodium N-stearoyl-glutamate, a precipitate is formed, and this precipitate is heated and dried to form about 93% of copper N-stearoyl-L-glutamate.
1? Obtained.
（製造例４）
Ｎ−ステアロイルーＬ−グルタミン酸ジナトリウム（味
の素株式会社製、商品名アミソフトＩｔｓ−２１）を水
１０００ｃｃに、８５ｇを溶解した水溶液を作戊した。(Production Example 4) An aqueous solution was prepared by dissolving 85 g of disodium N-stearoyl-L-glutamate (manufactured by Ajinomoto Co., Inc., trade name: Amisoft Its-21) in 1000 cc of water.
抗菌性を有する金属として、亜鉛を用い、塩化亜鉛２１
ｇを水１０００ｃｃに溶解した塩化亜鉛水溶液を作或し
た。そして、上記のＮ−ステアロイルーＬ−グルタミン
酸ジナトリウム水溶液に、上記の塩化亜鉛水溶液を混合
させることにより、沈澱物が形成され、この沈澱物を加
熱乾燥させてＮ−ステアロイルーＬ−１’ルタミン酸亜
鉛約９５９得た。Using zinc as a metal with antibacterial properties, zinc chloride 21
A zinc chloride aqueous solution was prepared by dissolving 1,000 cc of zinc chloride in 1,000 cc of water. Then, a precipitate is formed by mixing the above aqueous zinc chloride solution with the above aqueous solution of disodium N-stearoyl L-glutamate, and this precipitate is heated and dried to form a zinc N-stearoyl L-1' rutamate. I got about 959.
（実施例１）
製造例ｌにて得た平均粒子径３０μｌのＮ−アシルアミ
ノ酸銀ＩＯ部にエチレングリコールｌ００部および平均
粒子径７０μの微粒子（アエロジル）ｌ５０部を、ター
ビン翼を備えた撹拌装置に仕込み、３２ＧＯｒｐｍで４
時間撹拌した。角は終了後、４００メッシュの金網で微
粒子を分離してＮ一長鎖アシルアミノ酸銀のエチレング
リコールスラリーを得た。そして、このスラリーを重縮
合反応前のエチレングリコールｌ００重皿゛部に対し、
３部添加し常法により重合反応を行い固有粘度約０．６
のポリマーを得た。ポリマー中の粒子の分散状態を観察
したところ凝集粗大粒子は見当たらず良好な分散状態で
あった。得られたポリマーを用いて、紡糸温度２９７℃
、口金単孔当たリ（７）吐出ｆｌ ｌ． ７ｇ／分、紡
糸速度８２５０３１／分で溶融紡糸した。得られた繊維
中にはボイドおよびクラック状の結果は認められなく均
一性の高い繊維であった。(Example 1) 100 parts of ethylene glycol and 150 parts of fine particles (Aerosil) with an average particle size of 70 μl were added to IO parts of silver N-acylamino acid with an average particle size of 30 μl obtained in Production Example 1 using a stirring device equipped with a turbine blade. 4 at 32 GO rpm.
Stir for hours. After the cornering was completed, the fine particles were separated using a 400-mesh wire mesh to obtain an ethylene glycol slurry of N long-chain acylamino acid silver. Then, this slurry was added to 100 parts of ethylene glycol before the polycondensation reaction.
Add 3 parts and perform a polymerization reaction using a conventional method to obtain an intrinsic viscosity of approximately 0.6.
of polymer was obtained. When the dispersion state of the particles in the polymer was observed, no aggregated coarse particles were found, indicating a good dispersion state. Using the obtained polymer, the spinning temperature was 297°C.
, Nozzle single hole contact (7) Discharge fl l. Melt spinning was carried out at a spinning speed of 7 g/min and a spinning speed of 825,031/min. No voids or cracks were observed in the obtained fibers, and the fibers were highly uniform.
（実施例、２）
アクリロニトリル４９．０重量％、塩化ビニル５ｌ．０
重量％よりなるアクリロニトリル系共重合物ｌ００重量
部と、製造例２により得たＮ一長鎖アンル７ ミ／ ｎ
Ｗｉ Ｏ． ４ 重ｆｆｉ 部をアセトンにアクリロ
ニトリル系共重合物濃度が２５．０重量％になるように
溶解し、透明な紡糸原液を調製した。この原液をノズル
孔径０． ０８ｍｘ、孔数３００ホールのノズルを用い
て、３０％アセトン水溶液中へ押し出し、水洗後、１２
０゜Ｃで乾燥し、さらに３倍熱延伸して熱処理を１４Ｑ
゜Ｃで５分間行い本発明の抗菌性繊維を得た。同時にＮ
一長鎖アシルアミノ酸銀を添加しないものを同様に紡糸
し繊椎（比較例）を得た。(Example 2) Acrylonitrile 49.0% by weight, vinyl chloride 5l. 0
100 parts by weight of an acrylonitrile-based copolymer consisting of 100 parts by weight of acrylonitrile-based copolymer consisting of
Wi O. 4 parts of ffi were dissolved in acetone so that the acrylonitrile copolymer concentration was 25.0% by weight to prepare a transparent spinning stock solution. Apply this stock solution to a nozzle with a diameter of 0. Using a 08 m x 300 hole nozzle, extrude into a 30% acetone aqueous solution, wash with water,
Dry at 0°C, further heat stretch 3 times and heat treat for 14Q.
The antibacterial fiber of the present invention was obtained by heating at °C for 5 minutes. At the same time N
A filament without the addition of long-chain acylamino acid silver was similarly spun to obtain a filament (comparative example).
［実験］
上記実施例１、実施例２および比較例の繊維を用いて以
下の実験を行った。[Experiment] The following experiment was conducted using the fibers of Example 1, Example 2, and Comparative Example.
試験菌株として以下のものを用いた。The following strains were used as test strains.
Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ ＡＴＣ
Ｃ ６５３８Ｐ （黄色ブドウ球菌）Ｋ１ｅｂｓｉｅＬ
ｌａ ｐｎｅｕｍｏｎｉａｅ ＩＦＯ １３２７７
（クレブシェラ）そして、菌液の調製は、普通ブイヨン
培地で３５゜Ｃ、１８〜２０時間培養した菌液を同培地
を用いて、ｌ肩Ｑ当たりの閑数が５．ＯＸ１０５〜３．
ＯＸｌＯ”となるように調製したものを用いた。そして
、実施例ｌ、実施例２および比較例の繊維を用いて織布
を作或し、この織布をｌｌｌｌｘｘＸ １８ｘｘ区画の
大きさ（約０．２９ｆｆｉ）に切断し、そして、オート
クレープで、ｌ２１’ｃ， １５分間殺菌処理を行い、
次に、この繊維片に菌液を０． ２ｚＱ接種し、３５゜
Ｃで保存した。保存開始Ｏおよび１８時間後に滅菌緩衝
生理食塩液で繊維片中の生残菌を洗い出した。この洗い
出し液について菌数ａｒｔ定培用地［標準寒天培地（栄
研化学株式会社製）］を使用した混釈平板培養法（３５
゜Ｃ２日間）により生菌数を測定して、繊維片０．２９
当たりの生菌数に換算した。Staphylococcus aureus ATC
C 6538P (Staphylococcus aureus) K1ebsieL
la pneumoniae IFO 13277
(Klebsiella) A bacterial solution was prepared by culturing the bacterial solution in an ordinary bouillon medium at 35°C for 18 to 20 hours, using the same medium, and then culturing the bacterial solution at a culture rate of 5. OX105~3.
Then, a woven fabric was prepared using the fibers of Example 1, Example 2, and Comparative Example, and this woven fabric was divided into 18xx sections (approximately 0 .29ffi) and sterilized in an autoclave for 15 minutes.
Next, apply 0.0% bacterial solution to this fiber piece. 2zQ and stored at 35°C. Survival bacteria in the fiber pieces were washed out with sterile buffered physiological saline at 0 and 18 hours after the start of storage. For this washing solution, pour plate culture method (35
The number of viable bacteria was measured by
It was converted to the number of viable bacteria per unit.
実験は、それぞれ３つ行い、その結果は、第■表および
第２表に示す通りであった。Three experiments were conducted for each experiment, and the results were as shown in Tables 1 and 2.
第１表 ［黄色ブドウ球菌の経時変化１ （繊維片０．２９当たりの生菌数）１ ０内は平均値を示す。Table 1 [Time course of Staphylococcus aureus 1] (Number of viable bacteria per 0.29 pieces of fiber) 1 Values within 0 indicate average values.
第２表
（タレブシエラの経時変化１
（繊維片０．２９当たりの生閑数）ｌ
とにより、繊維材料との親和性が高く、繊維材料中に直
接添加されたとしても繊維物性を低下させることが少な
い。さらに、Ｎ一長鎖アシルアミノ酸塩は、基本骨格が
アミノ酸であるので、毒性が極めて少なく、安全である
。According to Table 2 (Temporal change of Talebsiella 1 (leaf count per 0.29 fiber pieces)), it has a high affinity with fiber materials, and even when added directly to fiber materials, it does not reduce the physical properties of fibers. Furthermore, since the basic skeleton of the N long-chain acylamino acid salt is an amino acid, it has extremely low toxicity and is safe.
０内は平均値を示す。Values within 0 indicate average values.
［発明の効果］[Effect of the invention]
Claims (3)
塩を含有することを特徴とする抗菌性繊維。(1) An antibacterial fiber characterized by containing an N-long chain acylamino acid salt of a metal having an antibacterial effect.
ステアロイル基、ラウロイル基、ミリストイル基、パル
ミトイル基のいずれかである請求項１記載の抗菌性繊維
。(2) The acyl group of the N-long chain acylamino acid salt is
The antibacterial fiber according to claim 1, which is any one of a stearoyl group, a lauroyl group, a myristoyl group, and a palmitoyl group.
ら選ばれたいずれか１つである請求項１に記載の抗菌性
繊維。(3) The antibacterial fiber according to claim 1, wherein the metal is any one selected from the group consisting of silver, copper, lead, zinc, and tin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16190A JPH0314612A (en) | 1990-01-03 | 1990-01-03 | Antimicrobial fiber |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16190A JPH0314612A (en) | 1990-01-03 | 1990-01-03 | Antimicrobial fiber |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63160407A Division JPH0692350B2 (en) | 1988-06-28 | 1988-06-28 | Antibacterial substance, antibacterial resin molded product containing the same, antibacterial synthetic fiber, antibacterial paper, antibacterial paint and synthetic resin antibacterial aquarium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0314612A true JPH0314612A (en) | 1991-01-23 |
Family
ID=11466318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16190A Pending JPH0314612A (en) | 1990-01-03 | 1990-01-03 | Antimicrobial fiber |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0314612A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405644A (en) * | 1992-11-17 | 1995-04-11 | Toagosei Chemical Industry Co., Ltd. | Process for producing antimicrobial fiber |
-
1990
- 1990-01-03 JP JP16190A patent/JPH0314612A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405644A (en) * | 1992-11-17 | 1995-04-11 | Toagosei Chemical Industry Co., Ltd. | Process for producing antimicrobial fiber |
| DE4339374C2 (en) * | 1992-11-17 | 2002-11-07 | Toagosei Co | Method for producing an antimicrobial fiber |
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