JPH02271855A - Vital phosthetic material such as artificial tooth root - Google Patents
Vital phosthetic material such as artificial tooth rootInfo
- Publication number
- JPH02271855A JPH02271855A JP1090835A JP9083589A JPH02271855A JP H02271855 A JPH02271855 A JP H02271855A JP 1090835 A JP1090835 A JP 1090835A JP 9083589 A JP9083589 A JP 9083589A JP H02271855 A JPH02271855 A JP H02271855A
- Authority
- JP
- Japan
- Prior art keywords
- root
- artificial tooth
- tooth root
- bone
- vital
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 14
- 229910052586 apatite Inorganic materials 0.000 claims abstract description 15
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims abstract description 15
- 238000005530 etching Methods 0.000 claims abstract description 5
- 230000002093 peripheral effect Effects 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 4
- 230000002378 acidificating effect Effects 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 abstract description 11
- 238000004140 cleaning Methods 0.000 abstract description 4
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 238000004506 ultrasonic cleaning Methods 0.000 abstract description 4
- FFTVPQUHLQBXQZ-KVUCHLLUSA-N (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O FFTVPQUHLQBXQZ-KVUCHLLUSA-N 0.000 abstract description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract description 2
- 229960004023 minocycline Drugs 0.000 abstract description 2
- 238000005245 sintering Methods 0.000 abstract description 2
- 239000002904 solvent Substances 0.000 abstract description 2
- 229940072172 tetracycline antibiotic Drugs 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 239000002344 surface layer Substances 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000007547 defect Effects 0.000 description 8
- 239000008187 granular material Substances 0.000 description 4
- 238000011109 contamination Methods 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 230000000704 physical effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- WTJXVDPDEQKTCV-UHFFFAOYSA-N 4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide;hydron;chloride Chemical compound Cl.C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2C1CC1C(N(C)C)C(=O)C(C(N)=O)=C(O)C1(O)C2=O WTJXVDPDEQKTCV-UHFFFAOYSA-N 0.000 description 1
- PLGPSDNOLCVGSS-UHFFFAOYSA-N Tetraphenylcyclopentadienone Chemical compound O=C1C(C=2C=CC=CC=2)=C(C=2C=CC=CC=2)C(C=2C=CC=CC=2)=C1C1=CC=CC=C1 PLGPSDNOLCVGSS-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000000739 chaotic effect Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229960002421 minocycline hydrochloride Drugs 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000000332 tooth crown Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ceramic Engineering (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Dental Prosthetics (AREA)
Abstract
Description
【発明の詳細な説明】
産業上の利用分野
本願は、歯牙欠損部或いは障害などによる置火を具部を
補綴処置するために、骨の欠を具部に補填される生体補
綴材に関する。DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present application relates to a bioprosthetic material in which a bone defect is filled in a tooth part in order to prosthetically treat a tooth defect caused by a tooth defect or an obstruction.
従来の技術
従来、歯牙欠損部或いは外科障害による骨欠損部を補綴
処置するために、顎骨に穿った埋入富に埋入して骨性結
合を生じさせるアパタイト人工歯根或いは骨欠損部に通
用する顎顔面補綴物の固定源としてのアパタイト・イン
ブラントは公知であり、これらは、一般に合成されたア
パタイト微粉法を常温下で圧粉後高温度（約１０５０°
Ｃ）のもとで焼結することにより作成される高密度アパ
タイト・セラミックスで構成される。BACKGROUND OF THE INVENTION Conventionally, in order to prosthetically treat tooth defects or bone defects due to surgical damage, apatite artificial tooth roots or bone defects have been used, which are implanted into a hole drilled in the jawbone to form an osseous union. Apatite implants as a fixation source for maxillofacial prostheses are well known, and they are generally made using a synthetic apatite powder method, which is compacted at room temperature and then heated to a high temperature (approximately 1050°C).
Comprised of high density apatite ceramics made by sintering under C).
発明が解決しようとする課題
ところで、アパタイトは局部的な骨欠損部に対する骨充
填材としても用いられており、出願人が行った多くの臨
床試験による経験によれば、骨充填材としてのアパタイ
ト顆粒を使用する際、顆粒充填域における骨形成が高密
度アパタイト顆粒に比し、マイクロポア（微小孔）を有
する多孔質アパタイト顆粒の方が、マイクロポアの存在
によって生体組織に対する親和性に優れ、骨形成に有効
であることが立証された。Problems to be Solved by the Invention Incidentally, apatite is also used as a bone filling material for localized bone defects, and according to the experience of many clinical trials conducted by the applicant, apatite granules as a bone filling material. When using bone formation in the granule-filled region, porous apatite granules with micropores have better affinity for living tissue than high-density apatite granules, and the presence of micropores allows for bone formation. It has been proven that it is effective for formation.
しかしながら、多孔質アパタイトから成る人工歯根を作
成した場合、高い物性が得られず、例えば咬合力に充分
耐えることができないという不都合を存する。However, when an artificial tooth root made of porous apatite is made, it has the disadvantage that high physical properties cannot be obtained and, for example, it cannot sufficiently withstand occlusal force.
そこで本願は、物性が高いとともに生物学的に多孔質の
特性を有する生体補綴材を提供することを目的としたも
のである。Therefore, the present application aims to provide a bioprosthetic material that has high physical properties and biologically porous characteristics.
課題を解決するための手段
本願は上記した目的を達成するために、高密度アバフィ
ト燃結材から成る人工歯根などの生体補綴材の外周面に
、エツチング加工を施して、その最表層を、多孔質構造
としたことを特徴とするものであり、好ましくは、例え
ばテトラサイクロン系抗生剤（塩酸ミノサイクリン）の
如き弱酸性の薬剤によってエツチング加工を施して成る
ものである。Means for Solving the Problems In order to achieve the above-mentioned object, the present application applies an etching process to the outer peripheral surface of a bioprosthetic material such as an artificial tooth root made of a high-density Abaphyte sintered material, and makes the outermost layer porous. It is characterized by a textured structure, and is preferably etched with a weakly acidic agent such as a tetracyclone antibiotic (minocycline hydrochloride).
実 施 例 以下、本願の実施例を図面にもとづいて詳述するる。Example Hereinafter, embodiments of the present application will be described in detail based on the drawings.
実施例は人工歯根の場合を例示しており、第１図は、歯
冠を支持する支台部（１）と、外周に小突起（１）°を
有した顎骨内に埋入する歯根部（２）とを一体に形成し
た高密度アパタイト焼結材（相対密度９０〜９９％）か
ら成る例えば太さが６．５〜３．５龍、高さが１１．０
〜７．０鶴の柱状の人工歯根を示しており、この人工歯
根の全体若しくは少なくとも骨内に埋入される歯根部（
２）を、力価１００ｍｇのテトラサイクリン系抗生剤（
塩化ミノサイクリン）を５０ｃｃの生理食塩水に熔解し
て得たＰＨ３前後の溶剤に浸漬し、室温において数分か
ら１時間程度放置する。The examples illustrate the case of an artificial tooth root, and Fig. 1 shows a tooth root to be implanted in the jawbone, which has an abutment part (1) that supports the tooth crown and a small protrusion (1) degree on the outer periphery. For example, the thickness is 6.5 to 3.5 mm and the height is 11.0 mm.
~7.0 The column-shaped artificial tooth root of the crane is shown, and the entire artificial tooth root or at least the tooth root part embedded in the bone (
2), a tetracycline antibiotic with a titer of 100 mg (
Minocycline chloride) is dissolved in 50 cc of physiological saline and immersed in a solvent with a pH of around 3, and left at room temperature for about a few minutes to about an hour.
このようにして、第２図で示すように歯根部（２）の最
表層ａ（０、数μ〜数μ）のアパタイトが多孔Ｐｉｔ構
造となった状態で、これを取り出して従来行われている
清掃及び滅菌方向例えば沌水を用いた超音波洗浄、アル
コールを用いた超音波洗浄等を適宜組み合わせた洗浄操
作し、次いで滅菌パックに封入保管するものであり、ま
た使用に際して・は、オートクレーブあるいはエチレン
・オキサイドガスで滅菌するものである。In this way, as shown in Fig. 2, the apatite in the outermost layer a (0, several microns to several microns) of the tooth root (2) has become a porous pit structure, and this is taken out and Cleaning and sterilization directions: For example, the product is cleaned using an appropriate combination of ultrasonic cleaning using chaotic water, ultrasonic cleaning using alcohol, etc., and then sealed and stored in a sterilized pack. It is sterilized using ethylene oxide gas.
しかして歯牙欠損部の補綴治療に際し、歯根部（２）を
顎骨に穿った埋入窩に埋入し、その外周面が骨組織と充
分に結合したのちに、前記支台部（１）に歯冠を取り付
けるものである。Therefore, when performing prosthetic treatment for a tooth-deficient area, the tooth root (2) is inserted into a socket drilled in the jawbone, and after its outer peripheral surface has fully bonded to the bone tissue, the tooth root (2) is inserted into the abutment (1). It is used to attach a dental crown.
なお骨欠損部に対する顎αｎ面補綴物等の固定源として
のインブラントの場合も、上記と同様に高密度アパタイ
ト焼結材から成るインブラントを弱酸性の薬剤に浸漬し
て、エツチング加工したのち、清掃及び滅菌処理するも
のである。In the case of an implant used as a fixation source for a jaw αn-plane prosthesis for a bone defect, the implant made of high-density sintered apatite is immersed in a weakly acidic agent and etched in the same manner as above. , cleaning and sterilization.
発明の効果
以上のように、本願によれば、最表層を除く全体が、高
密度アパタイト焼結材から成るので、極めて高い物性が
得られると共に、最表層が多孔質性であることにより、
生体組織との親和性に優れ、確実な治療効果を得ること
ができ、また生産過程において、外周面が汚染され、こ
の汚染が、通常の清掃及び滅菌方法によって除去できな
い場合でも、エツチング加工による腐蝕作用によって汚
染も確実に除去でき、汚染に伴う障害のない安定した治
療ができるなどの利点を有する。Effects of the Invention As described above, according to the present application, the entire body except the outermost layer is made of high-density sintered apatite material, so extremely high physical properties can be obtained, and since the outermost layer is porous,
It has excellent compatibility with living tissues and can provide a reliable therapeutic effect, and even if the outer surface is contaminated during the production process and this contamination cannot be removed by normal cleaning and sterilization methods, etching can prevent corrosion. It has the advantage that contamination can be reliably removed through its action, and stable treatment can be performed without problems associated with contamination.
図面は本願の実施例を示すもので、第１図は半裁断面図
、第２図は第１図Ｐ部の拡大断面図であ図中、（１）は
支台部、（２）は歯根部である。The drawings show an embodiment of the present application, and FIG. 1 is a half-cut sectional view, and FIG. 2 is an enlarged sectional view of section P in FIG. Department.
Claims (2)
生体補綴材の外周面に、エッチング加工を施して、その
最表層を、多孔質構造としたことを特徴とする人工歯根
などの生体補綴材。(1) A bioprosthesis such as an artificial tooth root, which is characterized by etching the outer peripheral surface of the bioprosthesis material, such as an artificial tooth root made of a high-density apatite sintered material, and making the outermost layer a porous structure. Material.
ことを特徴とする請求項１記載の人工歯根などの生体補
綴材。(2) The bioprosthetic material such as an artificial tooth root according to claim 1, wherein the etching process is performed using a weakly acidic chemical.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1090835A JPH02271855A (en) | 1989-04-12 | 1989-04-12 | Vital phosthetic material such as artificial tooth root |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1090835A JPH02271855A (en) | 1989-04-12 | 1989-04-12 | Vital phosthetic material such as artificial tooth root |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH02271855A true JPH02271855A (en) | 1990-11-06 |
Family
ID=14009645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1090835A Pending JPH02271855A (en) | 1989-04-12 | 1989-04-12 | Vital phosthetic material such as artificial tooth root |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH02271855A (en) |
-
1989
- 1989-04-12 JP JP1090835A patent/JPH02271855A/en active Pending
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