JPH02152920A - Composition for skin disinfection and cleansing - Google Patents
Composition for skin disinfection and cleansingInfo
- Publication number
- JPH02152920A JPH02152920A JP30543188A JP30543188A JPH02152920A JP H02152920 A JPH02152920 A JP H02152920A JP 30543188 A JP30543188 A JP 30543188A JP 30543188 A JP30543188 A JP 30543188A JP H02152920 A JPH02152920 A JP H02152920A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- present
- wiping
- phase
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 66
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 23
- 239000008213 purified water Substances 0.000 claims abstract description 17
- 239000000839 emulsion Substances 0.000 claims abstract description 11
- 239000003921 oil Substances 0.000 claims abstract description 11
- 239000002480 mineral oil Substances 0.000 claims abstract description 6
- 235000010446 mineral oil Nutrition 0.000 claims abstract description 4
- 230000001954 sterilising effect Effects 0.000 claims description 19
- 239000002736 nonionic surfactant Substances 0.000 claims description 12
- 230000000844 anti-bacterial effect Effects 0.000 claims description 8
- 239000002280 amphoteric surfactant Substances 0.000 claims description 6
- 239000003899 bactericide agent Substances 0.000 claims description 5
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract description 20
- 229960003237 betaine Drugs 0.000 abstract description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract description 7
- 208000010201 Exanthema Diseases 0.000 abstract description 6
- 201000005884 exanthem Diseases 0.000 abstract description 6
- 206010037844 rash Diseases 0.000 abstract description 6
- 208000003251 Pruritus Diseases 0.000 abstract description 5
- 230000007803 itching Effects 0.000 abstract description 5
- 229920002545 silicone oil Polymers 0.000 abstract description 4
- 229960000686 benzalkonium chloride Drugs 0.000 abstract description 3
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract description 3
- 239000000645 desinfectant Substances 0.000 abstract description 3
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 abstract description 3
- 230000000249 desinfective effect Effects 0.000 abstract description 2
- 239000004094 surface-active agent Substances 0.000 abstract 4
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- -1 medium-chain fatty acid triglycerides Chemical class 0.000 description 18
- 239000008280 blood Substances 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 15
- 230000000694 effects Effects 0.000 description 14
- 230000000052 comparative effect Effects 0.000 description 13
- 239000004205 dimethyl polysiloxane Substances 0.000 description 13
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 13
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 13
- 238000004140 cleaning Methods 0.000 description 11
- 239000006210 lotion Substances 0.000 description 11
- 235000014113 dietary fatty acids Nutrition 0.000 description 8
- 239000000194 fatty acid Substances 0.000 description 8
- 229930195729 fatty acid Natural products 0.000 description 8
- 210000004392 genitalia Anatomy 0.000 description 8
- 235000019198 oils Nutrition 0.000 description 8
- 229920001296 polysiloxane Polymers 0.000 description 8
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 8
- 150000004667 medium chain fatty acids Chemical class 0.000 description 7
- 230000028327 secretion Effects 0.000 description 7
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 6
- 230000002175 menstrual effect Effects 0.000 description 6
- LEEDMQGKBNGPDN-UHFFFAOYSA-N 2-methylnonadecane Chemical compound CCCCCCCCCCCCCCCCCC(C)C LEEDMQGKBNGPDN-UHFFFAOYSA-N 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 230000005906 menstruation Effects 0.000 description 4
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 125000000217 alkyl group Chemical group 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 210000000436 anus Anatomy 0.000 description 2
- 210000001099 axilla Anatomy 0.000 description 2
- 229960001950 benzethonium chloride Drugs 0.000 description 2
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 2
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 2
- 239000012459 cleaning agent Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 229940032094 squalane Drugs 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229960003500 triclosan Drugs 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- FFJCNSLCJOQHKM-CLFAGFIQSA-N (z)-1-[(z)-octadec-9-enoxy]octadec-9-ene Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCCCCCCC\C=C/CCCCCCCC FFJCNSLCJOQHKM-CLFAGFIQSA-N 0.000 description 1
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 1
- YUFLXDLVTAPPHN-UHFFFAOYSA-N 1-(4,5-dihydroimidazol-1-yl)ethanol Chemical compound CC(O)N1CCN=C1 YUFLXDLVTAPPHN-UHFFFAOYSA-N 0.000 description 1
- SHHOXQWCXVHCLT-UHFFFAOYSA-N 2-(2,2-diaminoethylamino)acetic acid;hydrochloride Chemical compound Cl.NC(N)CNCC(O)=O SHHOXQWCXVHCLT-UHFFFAOYSA-N 0.000 description 1
- GOHZKUSWWGUUNR-UHFFFAOYSA-N 2-(4,5-dihydroimidazol-1-yl)ethanol Chemical compound OCCN1CCN=C1 GOHZKUSWWGUUNR-UHFFFAOYSA-N 0.000 description 1
- XPALGXXLALUMLE-UHFFFAOYSA-N 2-(dimethylamino)tetradecanoic acid Chemical compound CCCCCCCCCCCCC(N(C)C)C(O)=O XPALGXXLALUMLE-UHFFFAOYSA-N 0.000 description 1
- IVLXQGJVBGMLRR-UHFFFAOYSA-N 2-aminoacetic acid;hydron;chloride Chemical compound Cl.NCC(O)=O IVLXQGJVBGMLRR-UHFFFAOYSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
- 101100136092 Drosophila melanogaster peng gene Proteins 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 102000008100 Human Serum Albumin Human genes 0.000 description 1
- 108091006905 Human Serum Albumin Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 229960001716 benzalkonium Drugs 0.000 description 1
- CYDRXTMLKJDRQH-UHFFFAOYSA-N benzododecinium Chemical compound CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 CYDRXTMLKJDRQH-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000035597 cooling sensation Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229960001484 edetic acid Drugs 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 229960001269 glycine hydrochloride Drugs 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005722 itchiness Effects 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 229920000259 polyoxyethylene lauryl ether Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
Abstract
Description
【発明の詳細な説明】
１束よＬ丑里旦Ｉ
本発明は皮膚の殺菌・清拭用組成物、より詳しくは特に
肛門周辺部、陰部周辺部、腋窩周辺部等の日常生活にお
いて清浄、清拭し難い皮膚部分の殺菌・清拭に適してお
り、２等部分を清拭することによって清潔に保持し、か
ぶれ、かゆみ等の症状の発生を防止し得る新しい組成物
に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a composition for disinfecting and cleaning the skin, more specifically, for cleaning and cleaning the skin in daily life, especially around the anus, around the genitals, around the axilla, etc. The present invention relates to a new composition that is suitable for sterilizing and wiping skin areas that are difficult to wipe, and that can be kept clean by wiping secondary areas and prevent the occurrence of symptoms such as rashes and itchiness.
慢−米一五一韮一應
従来より、月経時の経血、分泌物の処理には、生理ナプ
キン、タンポン等が利用され、女性陰部周辺部皮膚に残
存する血液、汚れ等については、トイレットペーパー、
ティッシュペーパー等で拭き取るのが一般的であるが、
皮膚に固着した血液、分泌物等の汚れは上記拭きとり操
作では充分に除去できず、不快であるばかりでなく、陰
部周辺部を清潔に保ち得す、かぶれ、かゆみ等の原因と
もなり、はとんどの女性はそれらの汚れを気にしている
にも拘らず、仕方のないことと諦めているのが現状であ
る。Chronic - Kome Ichigoichi Niraichio Traditionally, sanitary napkins, tampons, etc. have been used to treat menstrual blood and secretions during menstruation, and blood and dirt remaining on the skin around the female genital area can be removed by using the toilet. paper,
It is common to wipe it off with tissue paper, etc.
Stains such as blood and secretions stuck to the skin cannot be removed sufficiently by the wiping operation described above, which is not only uncomfortable, but also causes rashes, itching, etc. Even though most women are concerned about these stains, the current situation is that they have no choice but to give up.
上記経血、分泌物等の蛋白質、多糖類を含む粘稠溶液乃
至之等の固着した汚れは、水洗いにより除去するのが最
も適当であるが、実際上水洗いはできない場合が殆んど
である。また一部には清浄綿等の清拭具も開発されてお
り、その利用も試みられているが、これは−回当りのコ
ストが高くつき、しかもトイレには流せない等の欠点が
あり、実用上向改善の余地がおる。更に、トイレットペ
ーパー等に塗布して用いられるフオーム状の清拭剤も知
られているが、これは水溶性であり、上記塗布時にペー
パーが破れてしまう等の弊害がある。It is most appropriate to remove fixed stains such as menstrual blood, secretions, proteins, viscous solutions containing polysaccharides, etc. by washing with water, but in reality washing with water is not possible in most cases. . In addition, some cleaning tools such as clean cotton have been developed and attempts are being made to use them, but these have drawbacks such as high cost per use and not being able to be flushed down the toilet. There is room for practical improvement. Furthermore, foam-like cleaning agents that are applied to toilet paper and the like are also known, but these are water-soluble and have disadvantages such as the paper being torn when applied.
オイル状の清拭剤ではかかる弊害はなく、ペーパー強度
は保てるが、上記したように経血、分泌物等の蛋白質、
多糖類を含む粘稠溶液乃至それらの固着物の清拭効果自
体が充分でない致命的欠点がある。Oil-based cleaning agents do not have such adverse effects and can maintain the strength of the paper, but as mentioned above, proteins such as menstrual blood and secretions, etc.
A fatal drawback is that the wiping effect of viscous solutions containing polysaccharides and their adhered substances is not sufficient.
βが しようとする出 １、
本発明の目的は上記肛門周辺部、陰部周辺部、腋窩周辺
部等の日常生活において清浄、清拭し難い皮膚部分、殊
に月経時の女性陰部周辺部皮膚に残存する経血、分泌物
等の蛋白質、多糖類を含む粘１周溶液乃至之等の固着し
た汚れ等の清拭に適してあり、トイレットペーパー等の
清拭紙と共に用いることができ、清拭効果が高くしかも
その拭きとり時に皮膚への刺激や損傷がなく、該清拭に
よって皮膚部分を清潔に保持して、かぶれ、かゆみ等の
症状の発生を防止し得る新しい組成物を提供することに
ある。1. The purpose of the present invention is to apply to skin areas that are difficult to clean and wipe in daily life, such as the area around the anus, the area around the genitals, and the area around the axilla, especially the skin around the genital area of women during menstruation. It is suitable for cleaning stubborn stains such as residual menstrual blood, proteins such as secretions, viscous solutions containing polysaccharides, etc., and can be used with cleaning paper such as toilet paper. To provide a new composition that is highly effective and does not irritate or damage the skin when wiped off, and that can keep the skin area clean and prevent the occurrence of symptoms such as rash and itching. be.
本発明者らは鋭意研究を重ねた結果、上記目的が以下の
組成を有するＷ／Ｏ型エマルジョン形態の組成物により
達成されることを見出し、ここに本発明を完成するに至
った。As a result of extensive research, the present inventors have found that the above object can be achieved by a composition in the form of a W/O emulsion having the following composition, and have now completed the present invention.
即ち、本発明は下記組成範囲の（１〉〜（４）成分と精
製水とを含有し、Ｗ／Ｏ型エマルジョン形態を有するこ
とを特徴とする皮膚の殺菌・清拭用組成物に係わる。That is, the present invention relates to a composition for sterilizing and wiping the skin, which contains components (1> to (4)) in the following composition range and purified water, and is in the form of a W/O emulsion.
（１）合成油及び／又は鉱物油 ２０〜７０重世％（２
）非イオン界面活性剤 １〜２５重伍％（３）両
性界面活性剤 ０〜 ２重■％（４） ｆｆ
ｌ菌剤０．００１〜１重ｆ１ ％本発明組成物は、上記
特定組成を有するＷ／Ｏ型エマルジョン形態としたこと
に基づいて、水の清拭効果と油の紙強度保持効果とを合
せ有することができ、トイレットペーパー等に塗布する
等により実用でき、かくして従来法では認められない格
別の清拭効果と殺菌効果を秦し得る。しかして、従来か
かるエマルジョン形態及び実用形態の殺菌・清拭用組成
物は全く知られていない。(1) Synthetic oil and/or mineral oil 20-70% (2
) Nonionic surfactant 1 to 25% (3) Amphoteric surfactant 0 to 2% (4) ff
1 bactericidal agent 0.001 to 1 F1% The composition of the present invention combines the wiping effect of water and the paper strength retaining effect of oil based on the W/O type emulsion having the above-mentioned specific composition. It can be put to practical use by applying it to toilet paper, etc., and can thus provide exceptional wiping and sterilizing effects that are not possible with conventional methods. However, such emulsion and practical sterilizing and wiping compositions have not been known at all.
本発明組成物においては（１）成分として特定の油を用
いることを必須とする。該成分には、例えばトリオクタ
ン酸グリセリン、トリカプリル酸グリセリン、トリカプ
リン酸グリセリン等の炭素数４〜／Ｏの中鎖脂肪酸トリ
グリセリド項二ミリスチン酸イソプロピル、ミリスチン
酸オクチルドデシル、パルミチン酸イソプロピル等の炭
素数６〜３０の脂肪酸と炭素数１〜２０の１価アルコー
ルとのエステル類ニジメチルポリシロキサン、メチルフ
ェニルポリシロキサン等の鎖状シリコーン油；オクタメ
チルシクロテトラシロキサン、デカメチルシクロペンタ
シロキサン等の環状シリコーン油等の合成油、及び例え
ば流動パラフィン、流動イソパラフィン等の炭化水素類
等の鉱物油が包含される。之等の内では特にミリスチン
酸イソプロピル、ジメチルポリシロキサン等の合成油や
流動イソパラフィン等の鉱物油等が低粘性の面より好ま
しい。In the composition of the present invention, it is essential to use a specific oil as component (1). The components include, for example, medium-chain fatty acid triglycerides having 4 to 10 carbon atoms, such as glyceryl trioctanoate, glycerin tricaprylate, and glycerin tricaprate; 30 fatty acids and monohydric alcohols having 1 to 20 carbon atoms Chain silicone oils such as dimethylpolysiloxane and methylphenylpolysiloxane; Cyclic silicone oils such as octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane, etc. synthetic oils, and mineral oils such as hydrocarbons such as liquid paraffin and liquid isoparaffin. Among these, synthetic oils such as isopropyl myristate and dimethylpolysiloxane, and mineral oils such as liquid isoparaffin are particularly preferred in view of their low viscosity.
上記（１）成分はその一種を単独で又は二種以上を適宜
併用して、本発明組成物中に２０〜７０重量％、好まし
くは４０〜６０重四％の重量で配合され、これにより得
られる組成物に本発明所期の優れた効果を付与すること
ができる。The above component (1) is blended singly or in combination of two or more in an amount of 20 to 70% by weight, preferably 40 to 60% by weight, and thereby obtained. The excellent effects intended by the present invention can be imparted to the composition.
本発明組成物において（２）成分とする非イオン界面活
性剤及び（３）成分とする両性界面活性剤は、之等を配
合して最終的に調製される本発明組成物が、噴霧可能な
Ｗ／Ｏ型エマルジョン形態となることを前提として公知
の各種のものから適宜選択して用いられ、特に限定され
るものではないが、本発明組成物が皮膚の中でも特に敏
感な部分に適用され得るものであることを考慮すれば、
皮虜への刺激性ができるだけ少ないものであるのが望ま
しい。かかる性質を満たす上記非イオン界面活性剤は、
以下の（２−１）〜（２−４）に属するものに分類され
る。In the composition of the present invention, the nonionic surfactant as the component (2) and the amphoteric surfactant as the component (3) are such that the composition of the present invention, which is finally prepared by blending them, can be sprayed. The composition of the present invention can be applied to particularly sensitive areas of the skin, although it is not particularly limited and can be used by appropriately selecting from various known products on the premise that it will be in the form of a W/O emulsion. Considering that it is
It is desirable to have as little irritation to the skin as possible. The above-mentioned nonionic surfactant satisfying such properties is
It is classified into those belonging to the following (2-1) to (2-4).
（２−１）水溶性シリコーン類ニ
ジメチルポリシロキサンポリエチレングリコール共重合
体、ジメチルポリシロキサンポリプロピレングリコール
共重合体等の単独又は組合せ、或いは之等に更に数種の
シリコーン類を混合したもの、例えばトーレシリコーン
社製ＤＣＱ２−３２２５等を例示できる。(2-1) Water-soluble silicones Nidimethylpolysiloxane polyethylene glycol copolymer, dimethylpolysiloxane polypropylene glycol copolymer, etc. alone or in combination, or a mixture of several types of silicones, such as Toray An example is DCQ2-3225 manufactured by Silicone Co., Ltd.
（２−２）ポリグリセリン脂肪酸エステル類二デカグリ
セリルペンタオレエート、デカグリセリルヘプタオレエ
ート、デカグリセリルデカオレエート、ヘキサグリセリ
ルペンタオレエート、ヘキサグリセリルポリレジル−ト
等の単独又は粗合せ。(2-2) Polyglycerin fatty acid esters such as didecaglyceryl pentaoleate, decaglyceryl heptaoleate, decaglyceryl decaoleate, hexaglyceryl pentaoleate, hexaglyceryl polyresilate, etc. alone or in rough combinations.
（２−３）ポリオキシエチレンアルキルエーテル類：ポ
リオキシエチレンラウリルエーテル、ポリオキシエチレ
ンオレイルエーテル等の単独又は組合せ。(2-3) Polyoxyethylene alkyl ethers: polyoxyethylene lauryl ether, polyoxyethylene oleyl ether, etc. alone or in combination.
［２−４）その他： ポリオキシエチレン硬化ヒマシ油等。[2-4) Others: Polyoxyethylene hydrogenated castor oil, etc.
上記（２−１）〜（２−４）の内でｔよ特に（２〜１）
に属する水溶性シリコーン類が好適に使用できる。Among the above (2-1) to (2-4), especially (2-1)
Water-soluble silicones belonging to the following can be suitably used.
上記（２）成分はその一種を単独で又は二種以上を適宜
組合せて、本発明組成物中に１〜２５重四％重量ましく
は１〜１５重量％の範囲で配合され、これにより得られ
る組成物に本発明所期の優れた効果を付与できる。The above component (2) is blended alone or in an appropriate combination of two or more in the composition of the present invention in an amount of 1 to 25% by weight or 1 to 15% by weight. The excellent effects intended by the present invention can be imparted to the composition.
また上記性質を満足する両性界面活性剤としては、具体
的には例えば２−アルキル−Ｎ−カルボキシメチルヒド
ロキシエチルイミダゾリウムベタイン（アルキル＝Ｃ１
１〜Ｃ１□）、ラウリルジメチルアミノ酢酸ベタイン、
Ｗｆｍアルキルジアミノエチルグリシン（アルキル＝０
１２〜Ｃ１４）等を例示でき、之等の内では２−アルキ
ル−Ｎ−カルボキシメチルヒドロキシエチルイミダゾリ
ウムベタインが好ましい。上記（３）成分は本発明組成
物の必須成分ではないが、通常その一種を単独で又は二
種以上を併用して、本発明組成物中に２重量％まで、好
ましくは０．１〜１重四重量範囲で添加配合されるのが
好ましく、これにより本発明組成物の乳化状態等を更に
改善することができる。Further, as an amphoteric surfactant satisfying the above properties, specifically, for example, 2-alkyl-N-carboxymethylhydroxyethylimidazolium betaine (alkyl=C1
1-C1□), lauryldimethylaminoacetic acid betaine,
Wfm alkyldiaminoethylglycine (alkyl=0
12 to C14), among which 2-alkyl-N-carboxymethylhydroxyethylimidazolium betaine is preferred. Although the above component (3) is not an essential component of the composition of the present invention, it is usually used alone or in combination of two or more types in the composition of the present invention up to 2% by weight, preferably 0.1 to 1%. It is preferable to add and blend the compound in an amount of 4 to 40% by weight, thereby making it possible to further improve the emulsified state of the composition of the present invention.
更に本発明組成物には（４）成分として殺菌剤を０．０
０１〜１重堡％、好ましくは０．０１〜０．２重Ｍ％の
範囲で添加配合することを必須とする。ここで（４）成
分とする殺菌剤としては、例えば塩酸アルキルジアミノ
エチルグリシン（アルキル−主にＣ１□〜Ｃ１４）、塩
化ベンザルコニウム、塩酸クロルヘキシジン、グルコン
酸クロルヘキシジン、塩化ベンゼトニウム、トリクロカ
ルパン、トリクロサン、ハロカルパン等を例示できる。Furthermore, the composition of the present invention contains 0.00% of a bactericide as component (4).
It is essential to add and blend in the range of 0.01 to 1% by weight, preferably 0.01 to 0.2% by weight. Examples of the bactericide used as component (4) include alkyldiaminoethylglycine hydrochloride (alkyl-mainly C1□ to C14), benzalkonium chloride, chlorhexidine hydrochloride, chlorhexidine gluconate, benzethonium chloride, triclocarpan, triclosan. , halocarpan and the like.
上記の内で塩酸アルキルジアミノエチルグリシンは、前
記（３）成分とする両性界面活性剤としても用いること
ができ、この場合はその使用量は前記（３）成分と該（
４）成分との合計量範囲とすることができる。Among the above, alkyldiaminoethylglycine hydrochloride can also be used as an amphoteric surfactant as the component (3), and in this case, the amount used is the same as that of the component (3).
4) The total amount of the ingredients can be ranged.
本発明組成物中、特に低粘性、好ましくは２０℃での組
成物全体の粘度が５ＱＣ３以下であり、且つＷｌＯ型エ
マルジョン状態で優れた安定性を有する点より好ましい
ものとしては、例えば（１）成分としてジメチルポリシ
ロキサン等の鎖状シリコーン油と（２）成分として（２
−１）に属する水溶性シリコーン類とを組合せたもの、
並びに（１）成分として流動パラフィン等の鉱物油と（
２）成分として（２−２）に属するポリグリセリン脂肪
酸エステルとを組合せたものを例示できる。Among the compositions of the present invention, preferred are those having particularly low viscosity, preferably the viscosity of the entire composition at 20°C of 5QC3 or less, and excellent stability in the WIO emulsion state, for example, (1) Chain silicone oil such as dimethylpolysiloxane as a component and (2) as a component.
−1) in combination with water-soluble silicones belonging to
and (1) mineral oil such as liquid paraffin as a component (
As the 2) component, a combination with a polyglycerol fatty acid ester belonging to (2-2) can be exemplified.
本発明組成物には、更に必要に応じて公知の各種消炎剤
等の薬効剤、パラベン等の防腐剤、ブチルじドロキシト
ルエン（ＢＨＴ） 、ビタミンＥ、エデト酸等の安定化
剤、香料、消臭剤等の適量を添加配合でき、更に清涼感
を高める等の目的でエタノール等の低級アルコール類ヤ
Ｑ−メントール等を添加配合したり、エモリエント剤と
してのオリーブ油、ホホバ油、ヒマシ油、パーム油、ア
ーモンド油、ヤシ油等の植物油やラノリン、スクワラン
等の動物油等を添加配合することもできる。The composition of the present invention may further contain medicinal agents such as various known anti-inflammatory agents, preservatives such as parabens, stabilizers such as butyl didroxytoluene (BHT), vitamin E, edetic acid, fragrances, etc., as necessary. Appropriate amounts of deodorants, etc. can be added and blended, and lower alcohols such as ethanol, Q-menthol, etc. can be added and blended for the purpose of increasing the cooling sensation, and olive oil, jojoba oil, castor oil, palm oil, etc. can be added as emollients. Oil, vegetable oils such as almond oil and coconut oil, and animal oils such as lanolin and squalane may also be added.
本発明組成物は、上記（１）〜（４）成分及び必要に応
じて他の添加剤等の所定量と、残り精製水とを用いて、
通常の方法に従い容易にＷ／Ｏ型エマルジョン状態に調
製することができる。該エマルジョンの調製は、例えば
最も基本的には、各成分中の油性成分と水性成分とを別
途混合調製し、前者に後者を少量ずつ添加しながらホモ
ミキサー等の適当な装置を用いて撹拌混合することによ
り実施される。The composition of the present invention uses predetermined amounts of the above components (1) to (4) and other additives as necessary, and the remaining purified water.
It can be easily prepared into a W/O type emulsion according to a conventional method. For example, the emulsion is most basically prepared by separately mixing the oily component and aqueous component of each component, and adding the latter little by little to the former while stirring and mixing using a suitable device such as a homomixer. It is implemented by
かくして調製されるＷ／Ｏ型エマルジョン形態の本発明
組成物は、これを適当な容器に充填して製品とされ、一
般にはその適当量をトイレットペーパー等の清拭紙に噴
霧、滴下等により塗布後、該清拭紙で皮膚部分を拭きと
る方法により実用される。従って、上記製品は通常の蓄
圧式ポンプボトル等を利用したり、各種の噴射剤等を用
いたスプレー形態とされるのが実用に適しており好まし
い。また上記製品の実用は、例えば月経時の女性陰部周
辺部、排便後の肛門周辺部、入浴できないときの陰部周
辺部、腋窩周辺部等の予め固着した経血、分泌物、汚物
等をトイレットペーパー、ティッシュペーパー等で拭き
とった後に、本製品を数回スプレーした清拭紙で拭きと
り仕上げするのが適当であり、これにより充分な清拭効
果を奏し１ｑ、上記皮膚部分を清潔に保持して、かぶれ
、かゆみその他の症状の発生、悪化を確実に防止するこ
とができる。また、本製品を直接陰部周辺部、肛門周辺
部、腋窩周辺部等に塗布し、次いでトイレットペーパー
、ティッシュペーパー等で拭きとる方法によっても適用
でき、この適用によっても本発明所期の効果を秦１ノ得
る。The composition of the present invention in the form of a W/O emulsion thus prepared is made into a product by filling it into a suitable container, and is generally applied in an appropriate amount onto cleaning paper such as toilet paper by spraying, dropping, etc. Afterwards, it is put to practical use by wiping the skin area with the wiping paper. Therefore, it is suitable and preferable for the above-mentioned product to be used in a conventional pressure accumulating pump bottle or in the form of a spray using various propellants. The practical use of the above product is, for example, to remove pre-fixed menstrual blood, secretions, filth, etc. from the genital area during menstruation, the anal area after defecation, the genital area when bathing is not possible, the axillary area, etc. After wiping with tissue paper, etc., it is appropriate to finish by wiping with a cleaning paper sprayed with this product several times.This provides a sufficient wiping effect and keeps the skin area clean. This can reliably prevent the occurrence and aggravation of rashes, itching, and other symptoms. In addition, this product can be applied directly to the genital area, anal area, axillary area, etc., and then wiped off with toilet paper, tissue paper, etc. This application also achieves the intended effect of the present invention. Get 1 no.
及−虱一座−盈−１
本発明の殺菌・清拭用組成物は、例えばこれをトイレッ
トペーパー等の清拭紙に付着させて実用することによっ
て、日常生活で清浄・清拭困難な皮膚部分の清拭を充分
効果的に行なうことができ、特に月経時の女性陰部周辺
部に付着する経血、分泌物等の清拭効果に優れ、上記皮
膚部分の殺菌効果を秦し得、該部分を清潔に保持して、
かゆみヤかぶれの発生を防止できる。しかも上記実用の
際、清拭紙が破れるおそれはなく、拭きとり感が非常に
良好であり、ベタツキ等の不快感もなく、また痛みや刺
激を与えるおそれもない。The sterilizing and wiping composition of the present invention can be applied to skin areas that are difficult to clean and wipe in daily life, for example by applying it to wiping paper such as toilet paper. It is particularly effective in wiping away menstrual blood, secretions, etc. that adhere to the female genital area during menstruation, and has a bactericidal effect on the skin area. keep it clean and
It can prevent itching and rashes. Moreover, during the above-mentioned practical use, there is no risk of the wiping paper being torn, the wiping feeling is very good, there is no discomfort such as stickiness, and there is no risk of causing pain or irritation.
実 施 例
以下、本発明を更に詳しく説明するため実施例及び比較
例を挙げるが、本発明は之等に限定されるものではない
。EXAMPLES Examples and comparative examples are given below to explain the present invention in more detail, but the present invention is not limited thereto.
尚、各側において用いた試薬は次の通りでおる。The reagents used on each side are as follows.
○シリコーン系非イオン界面活性剤：
ｒＤｃ−０２−３２２５ＣＪ （トーレ・シリコーン
社製）
Ｏポリグリセリン脂肪酸エステル；
ヘキサグリセリンポリレジル−ト（ｌｌｅｘａｇ Ｉｙ
ｎ ：日光ケミカルズ社製）
０中鎖脂肪酸トリグリセリド：
「パナセート８／ＯＪ（日本油脂社製）０２−フルキル
−Ｎ−力ルボキシメチルヒドロキシエチルイミダゾリニ
ウムベタイン：
ｒＨＩＲＡＮＯＬ Ｃ２）Ｉ Ｊ （ミラノール社製
）０塩酸アルキルジアミノエチルグリシン：ｒＴＥＧｏ
−５１Ｊ （日本商事社製）実施例 １
Ａ相 （す／Ｗ駒ジメ
チルポリシロキサン ３５中鎖脂肪酸トリ
グリセリド ５シリコーン系非イオン界面
活性剤 ／ＯＢ相
２−アルキル−
ヒドロキシエヂルイミダゾリニウムベタイン塩酸アルキ
ルジアミノエチルグリシン ０． ０５精製水
適量上記Ａ相及びＢ相をそれぞ
れ７０℃以上に加温した後、Ｂ相にＡ相を少しずつ加え
ながら、ホモミキサーにて３ ０ ０ ０ １’ｐｍで
撹拌しながら３０’Ｃまで冷却ざぜてＷ／Ｏ型ローショ
ン形態の本発明殺菌・清拭用組成物を得た。○Silicone-based nonionic surfactant: rDc-02-3225CJ (manufactured by Torre Silicone) O polyglycerin fatty acid ester; hexaglycerin polyresilate (llexag Iy
n: Nikko Chemicals Co., Ltd.) 0 Medium-chain fatty acid triglyceride: Panacet 8/OJ (Nippon Oil & Fats Co., Ltd.) 02-Furkyl-N-ruboxymethylhydroxyethylimidazolinium betaine: rHIRANOL C2) I J (Milanol Co., Ltd.) ) 0 alkyldiaminoethylglycine hydrochloride: rTEGo
-51J (manufactured by Nippon Shoji Co., Ltd.) Example 1 A phase (S/W Koma dimethylpolysiloxane 35 Medium chain fatty acid triglyceride 5 Silicone nonionic surfactant /OB phase 2-Alkyl- hydroxyedylimidazolinium betaine alkyl hydrochloride Diaminoethylglycine 0.05 Purified water
After heating appropriate amounts of the above phases A and B to 70°C or higher, add phase A little by little to phase B and cool to 30°C while stirring at 3000 1'pm with a homomixer. A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained.
実施例 ２
Ａ相 （Ｗ／Ｗ％）ジ
メチルポリシロキサン ３５中鎖脂肪酸ト
リグリセリド ５シリコ一ン系非イオン界
面活性剤 ／ＯＢ相
２−アルキル−Ｎ−力ルボキシメチル ０．５ヒドロキ
シエチルイミダゾリニウムベタイン塩化ベンザルコニウ
ム ０． ０５精製水
適量上記Ａ相及びＢ相を用いて、実施例
１と同様にしてＷ／Ｏ型ローション形態の本発明殺菌・
清拭用組成物を得た。Example 2 Phase A (W/W%) Dimethylpolysiloxane 35 Medium chain fatty acid triglyceride 5 Silicoline nonionic surfactant /OB phase 2-Alkyl-N-hydroxymethyl 0.5 Hydroxyethyl imidazolinium betaine chloride Benzalkonium 0. 05 Purified water
Using appropriate amounts of the above phase A and phase B, the present invention was sterilized in the form of a W/O type lotion in the same manner as in Example 1.
A cleaning composition was obtained.
実施例 ３
Ａ相 （Ｗ／繭）軽質
流動イソパラフィン ４０ミリスチン酸イ
ソプロピル ８ポリグリセリン脂肪酸エス
テル ２Ｂ相
塩酸アルキルジアミノエチルグリジン ０．２精製水
適量上記Ａ相及びＢ相を
用いて、実施例１と同様にしてＷ／Ｏ型ローション形態
の本発明殺菌・清拭用組成物を得た。Example 3 Phase A (W/cocoon) Light liquid isoparaffin 40 Isopropyl myristate 8 Polyglycerin fatty acid ester 2B phase Alkyl diaminoethyl glycine hydrochloride 0.2 Purified water
A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
実施例 ４
Ａ相 （Ｗ／Ｗ％）ジ
メチルポリシロキサン ２５中鎖脂肪酸ト
リグリセリド ５シリコ一ン系非イオン界
面活性剤 ２０Ｂ相
２−アルキル−Ｎ−カルボキシメチル
ヒドロキシエチルイミダゾリニウムベタイン塩酸アルキ
ルジアミノエチルグリシン ｏ． ｏｉ精製水
適量上記Ａ相及びＢ相を用いて
、実施例１と同様にしてＷ／Ｏ型ローション形態の本発
明殺菌・清拭用組成物を得た。Example 4 Phase A (W/W%) Dimethylpolysiloxane 25 Medium chain fatty acid triglyceride 5 Silicoline nonionic surfactant 20 Phase B 2-Alkyl-N-carboxymethylhydroxyethylimidazolinium betaine Alkyldiaminoethylglycine hydrochloride o. oi purified water
A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
実施例 ５
Ａｔ′目
（Ｗ／−
％）ジメチルポリシロキサン ４０ミリス
チン酸イソプロピル ５シリコ一ン系非イ
オン界面活性剤 ５Ｂ相
塩酸アルキルジアミノエチルグリジン ０．３精製水
適量上記Ａ相及びＢ相を
用いて、実施例１と同様にしてＷ／Ｏ型ローション形態
の本発明殺菌・清拭用組成物を得た。Example 5 At'th
(W/-
%) Dimethylpolysiloxane 40 Isopropyl myristate 5 Silicoline nonionic surfactant 5B phase Alkyldiaminoethyl glycine hydrochloride 0.3 Purified water
A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
実施例 ６
Ａ相 （１４／關）ジ
メチルポリシロキサン ３５ミリスチン酸
イソプロピル ５シリコ一ン系非イオン界
面活性剤 ／Ｏトリクロカルパン
０．１Ｂ相
２−アルキル−Ｎ−カルボキシメチル
ヒドロキシエチルイミダゾリニウムベタイン精製水
適ｌ上記Ａ相及びＢ相を用
いて、実施例１と同様にしてＷ／Ｏ型ローション形態の
本発明殺菌・清拭用組成物を得た。Example 6 Phase A (14/related) Dimethylpolysiloxane 35 Isopropyl myristate 5 Silicoline nonionic surfactant /O triclocarpane
0.1B phase 2-alkyl-N-carboxymethylhydroxyethylimidazolinium betaine purified water
A sterilizing/wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using the above Phases A and B.
実施例 ７
Ａ相 （Ｗ／川用質流
動イソパラフィン ３５ミリスチン酸イソ
プロピル ５ポリグリセリン脂肪酸エステ
ル ５トリクロサン
０．２Ｂ相
２−アルキル−Ｎ−カルボキシメチル １ヒドロキシ
エチルイミダゾリニウムベタイン精製水
適量上記Ａ相及びＢ相を用いて、実施
例１と同様にしてＷ／Ｏ型ローション形態の本発明殺菌
・清拭用組成物を得た。Example 7 Phase A (W/river grade liquid isoparaffin 35 isopropyl myristate 5 polyglycerin fatty acid ester 5 triclosan
0.2B phase 2-alkyl-N-carboxymethyl 1-hydroxyethylimidazolinium betaine purified water
A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
実施例 ８
Ａ相 （誓／韓％）ジ
メチルポリシロキサン ３５中鎖脂肪酸ト
リグリセリド ５シリコ一ン系非イオン界
面活性剤 ／ＯＢ相
塩酸アルキルジアミノエチルグリジン １．０塩酸アル
キルジアミノエチルグリシン ０．０５精製水
適量上記Ａ相及びＢ相（但し塩
酸アルキルジアミノエチルグリシン１．０％は両性界面
活性剤として、同０．０５％は殺菌剤として利用）を用
いて、実施例１と同様にしてＷ／Ｏ型ローション形態の
本発明殺菌・清拭用組成物を得た。Example 8 Phase A (%) Dimethylpolysiloxane 35 Medium chain fatty acid triglyceride 5 Silicoline nonionic surfactant /OB phase Alkyldiaminoethylglycine hydrochloride 1.0 Alkyldiaminoethylglycine hydrochloride 0.05 Purification water
Using appropriate amounts of the above phase A and phase B (however, 1.0% of alkyl diaminoethylglycine hydrochloride is used as an amphoteric surfactant and 0.05% of the same is used as a bactericide), W/O was prepared in the same manner as in Example 1. A sterilizing and wiping composition of the present invention in the form of a mold lotion was obtained.
実施例 ９
Ａ相 （Ｗ／Ｗ％）軽
質流動イソパラフィン ４０ミリスチン酸
イソプロピル ８ポリグリセリン脂肪酸エ
ステル ２Ｂ相
グルコン酸クロルヘキシジン ０．２精製水
適量上記Ａ相及びＢ相を
用いて、実施例１と同様にしてＷ／Ｏ型ローション形態
の本発明殺菌・清拭用組成物を得た。Example 9 Phase A (W/W%) Light liquid isoparaffin 40 Isopropyl myristate 8 Polyglycerin fatty acid ester 2B phase Chlorhexidine gluconate 0.2 Purified water
A sterilizing/wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
実施例／Ｏ
Ａ相 （吋／用ジメチ
ルポリシロキサン ２５中鎮脂肪酸トリグ
リセリド ５シリコ一ン系非イオン界面活
性剤 ２０Ｂ相
２−アルキル−Ｎ−カルボキシメチル
ヒドロキシエチルイミダゾリニウムベタイン塩化ベンゼ
トニウム ０．２精製水
適量上記Ａ相及びＢ相を用いて、実
施例１と同様にしてＷ／Ｏ型ローション形態の本発明殺
菌・清拭用組成物を得た。Example/O Phase A Dimethylpolysiloxane 25 Neutral fatty acid triglyceride 5 Silicoline nonionic surfactant 20 Phase B 2-Alkyl-N-carboxymethylhydroxyethylimidazolinium betaine Benzethonium chloride 0.2 Purification water
A sterilizing and wiping composition of the present invention in the form of a W/O type lotion was obtained in the same manner as in Example 1 using appropriate amounts of the above Phases A and B.
比較例 １
Ａ相 （−／脇）ジメ
チルポリシロキサン ３５中鎖脂肪酸トリ
グリセリド ／Ｏモノオレイン酸ソルビタン
２モノオレイン酸ポリオキシエチレンソ
ルビタン（ＩＯＥ．Ｏ） ３Ｂ相
セチルｖｒＬ酸ナトリウム ０．１精
製水 適量・上記Ａ相及
びＢ相を用いて、実施例］と同様にしてＯ／Ｗ型ローシ
ョン形態の比較清拭用組成物を得た。Comparative Example 1 Phase A (-/side) Dimethylpolysiloxane 35 Medium chain fatty acid triglyceride /O Sorbitan monooleate 2 Polyoxyethylene sorbitan monooleate (IOE.O) Phase 3 Cetyl vr Sodium L 0.1 Purified water Appropriate amount. A comparative cleaning composition in the form of an O/W type lotion was obtained in the same manner as in Example using the above Phase A and Phase B.
比較例 ２
（Ｗ／Ｗ％）
ジメチルポリシロキサン ７０中鎖脂肪酸
トリグリセリド ／Ｏスクワラン
２０上記各成分を室温で均一になるま
で撹拌して比較清拭用組成物を得た。Comparative Example 2 (W/W%) Dimethylpolysiloxane 70 medium chain fatty acid triglyceride /O squalane
20 Each of the above components was stirred at room temperature until uniform, to obtain a comparative wiping composition.
〈効力試験〉
本発明組成物の効果を確認するため、以下の項目につい
て試験を行なった。<Efficacy Test> In order to confirm the effects of the composition of the present invention, tests were conducted on the following items.
■ ペイパー強度
実施例１で得た本発明組成物及び比較例１で）ｑだ比較
組成物並びに精製水を試料として、以下の試練を行なっ
た。即ち、トイレットペーパー１１．５Ｘ２０Ｃｍの上
端を固定し、下端を重りで引張り、各試料の０．１ｍ１
２をトイレットペーパーに噴霧付着させ、該ペーパーの
切断される時の重りの重さ（ｃ［を測定した。(2) Paper strength The following tests were carried out using the composition of the present invention obtained in Example 1, the comparative composition (comparative example 1), and purified water as samples. That is, the upper end of a 11.5 x 20 cm toilet paper was fixed, the lower end was pulled with a weight, and 0.1 m1 of each sample was
2 was sprayed onto toilet paper, and the weight (c[) of the weight when the paper was cut was measured.
結果を下記第１表に示す。The results are shown in Table 1 below.
第 １ 表
上記第１表より、本発明組成物試料（実施例１）は、精
製水に比し顕著なペイパー強度の増加が認められ、実用
上充分なペイパー強度を有することが判る。これに対し
て比較例１の試料は実施例１のそれと水量が同じである
にも拘らず、精製水と同程度のペイパー強度しかなく実
用に耐えられないことが判る。Table 1 From Table 1 above, it can be seen that the composition sample of the present invention (Example 1) has a remarkable increase in paper strength compared to purified water, and has a paper strength sufficient for practical use. On the other hand, although the sample of Comparative Example 1 had the same amount of water as that of Example 1, it was found that the paper strength was only about the same as that of purified water and could not be put to practical use.
また前記実施例２〜／Ｏに示した本発明組成物も、同一
試験の結果、上記実施例１のそれと略々同等のペーパー
強度増加が認められた。In addition, as a result of the same test, the compositions of the present invention shown in Examples 2 to 2/O were also found to have an increase in paper strength that was approximately the same as that of Example 1.
■ 血液除去能試験
実施例１で得た本発明組成物及び比較例２で得た比較組
成物を試料として、以下の試験を行なった。即ち、人血
２０μＱをヒト前腕屈側皮膚に塗布し、ドライヤーで完
全に乾燥させた。次いで各試料（約０．１ｍ１２）を噴
霧したトイレットペーパー及び対照（コントロール）と
して何らの薬剤も塗布しなかった無処理トイレットペー
パーを用いて、上記乾燥面を均等の力で／Ｏ回拭きとり
、その除去率（％）を求め、各試料の清拭効果を調べた
。尚、血液除去率はトイレットペーパーに拭きとられた
血液を溶血させ、その吸光度を可視部にて測定すること
により求めた。(2) Blood removal ability test The following tests were conducted using the composition of the present invention obtained in Example 1 and the comparative composition obtained in Comparative Example 2 as samples. That is, 20 μQ of human blood was applied to the skin on the crooked side of a human forearm and completely dried with a hair dryer. Then, using toilet paper sprayed with each sample (approximately 0.1 m12) and untreated toilet paper to which no drug was applied as a control, the dry surface was wiped /0 times with equal force, The removal rate (%) was determined and the cleaning effect of each sample was investigated. The blood removal rate was determined by hemolyzing blood wiped onto toilet paper and measuring its absorbance in the visible region.
得られた結果を下記第２表に示す。The results obtained are shown in Table 2 below.
第 ２ 表
上記第２表より、比較試料（比較例２）及びコントロー
ルでは血液を除去する効果はないのに比べて、本発明組
成物試料（実施例１）は、顕著な血液除去効果を奏する
ことが明らかである。Table 2 From Table 2 above, the comparative sample (Comparative Example 2) and the control have no blood removing effect, while the composition sample of the present invention (Example 1) has a significant blood removing effect. That is clear.
上記と同一試験の結果、実施例２〜／Ｏ記載の本発明組
成物も、実施例１のそれと略々同様の血液除去効果を秦
すると認められた。As a result of the same test as above, it was found that the compositions of the present invention described in Examples 2 to 2/O had substantially the same blood removal effect as that of Example 1.
■ 殺菌効果試験
本発明殺菌・清拭用組成物０．５ｍ１２．／Ｏ０ｍｇ／
鵬のヒト血清アルブミン０．５１１１１２及び菌液２５
μＱ（菌数約／Ｏ５個）を試験管に入れ、所定時間（１
，３及び５時間）放置し、その後生菌数を測定し、本発
明組成物の殺菌効果を調べた。■ Sterilizing effect test: Sterilizing and wiping composition of the present invention 0.5ml 12. /O0mg/
Peng's human serum albumin 0.511112 and bacterial fluid 25
Put μQ (approximately 5 bacteria) into a test tube and
, 3 and 5 hours), and then the number of viable bacteria was measured to examine the bactericidal effect of the composition of the present invention.
尚、比較対照として生理食塩水及び実施例１及び２の各
処方よりそれぞれ殺菌剤成分としての塩酸アルキルジア
ミノエチルグリジン及び塩化ベンザルコニウムを除いた
ものについても同様の効果を調べた。As a comparative control, similar effects were investigated using physiological saline and the formulations of Examples 1 and 2 in which the alkyl diaminoethyl glycine hydrochloride and benzalkonium chloride as disinfectant components were removed, respectively.
結果は第１図〜第４図に示す通りである。The results are shown in FIGS. 1 to 4.
各図は横軸に時間（ｈｒ）を、縦軸に生菌数の対数（Ｉ
Ｑ（］／Ｏ［生菌数］）をとり、各供試液中の生菌数の
経時変化を見たものであり、第１図及び第２図は大腸菌
数を、第３図及び第４図は緑膿菌数を調べた結果である
。In each figure, the horizontal axis represents time (hr), and the vertical axis represents the logarithm of the number of viable bacteria (I
Figures 1 and 2 show the number of E. coli bacteria, and Figures 3 and 4 show the number of viable bacteria in each test solution. The figure shows the results of examining the number of Pseudomonas aeruginosa.
また第１図及び第３図は本発明組成物として実圧倒１の
組成物を用いた結果（図中（１）として示す）でめり、
第２図及び第４図は本発明組成物として実施例２の組成
物を用いた結果（図中（１）として示す）でおり、各図
中、（２）は（１）として示す組成物より殺菌成分を除
いたものの結果であり、（３）は対照とする生理食塩水
の結果でおる。In addition, FIGS. 1 and 3 show the results of using the composition of the present invention which was actually overwhelmingly 1 (indicated as (1) in the figure).
Figures 2 and 4 show the results of using the composition of Example 2 as the composition of the present invention (shown as (1) in the figures), and (2) in each figure shows the composition shown as (1). These are the results with the bactericidal component removed, and (3) is the result of physiological saline as a control.
２等各図より、本発明組成物は、顕著な殺菌効果を奏す
ることが明らかである。From the second and second figures, it is clear that the composition of the present invention has a remarkable bactericidal effect.
図面の簡単な説明
第１図乃至第４図は、本発明殺菌・清拭組成物の殺菌効
果を調べた結果を示すグラフである。BRIEF DESCRIPTION OF THE DRAWINGS FIGS. 1 to 4 are graphs showing the results of examining the sterilizing effect of the sterilizing and wiping composition of the present invention.
（以 上） 第 図 吟 間（ｈ「） 間（ｈ「） 第 図 、時 間 （ｈ「） 第 図 時 間 （ｈ「）(that's all) No. figure Gin Between (h ``) Between (h ``) No. figure ,Time while (h ``) No. figure Time while (h ``)
Claims (1)
含有し、Ｗ／Ｏ型エマルジョン形態を有することを特徴
とする皮膚の殺菌・清拭用組成物。 （１）合成油及び／又は鉱物油２０〜７０重量％ （２）非イオン界面活性剤１〜２５重量％ （３）両性界面活性剤０〜２重量％ （４）殺菌剤０．００１〜１重量％[Scope of Claims] [1] A composition for sterilizing and wiping the skin, which contains components (1) to (4) in the following composition range and purified water, and has a W/O emulsion form. thing. (1) 20 to 70% by weight of synthetic oil and/or mineral oil (2) 1 to 25% by weight of nonionic surfactant (3) 0 to 2% by weight of amphoteric surfactant (4) 0.001 to 1% of bactericide weight%
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63305431A JPH0720856B2 (en) | 1988-12-01 | 1988-12-01 | Composition for sterilizing and cleaning skin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63305431A JPH0720856B2 (en) | 1988-12-01 | 1988-12-01 | Composition for sterilizing and cleaning skin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02152920A true JPH02152920A (en) | 1990-06-12 |
| JPH0720856B2 JPH0720856B2 (en) | 1995-03-08 |
Family
ID=17945053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63305431A Expired - Lifetime JPH0720856B2 (en) | 1988-12-01 | 1988-12-01 | Composition for sterilizing and cleaning skin |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0720856B2 (en) |
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| WO1997048377A1 (en) * | 1996-06-15 | 1997-12-24 | Smithkline Beecham Plc | Skin wash compositions comprising triclocarban and surfactants |
| US5756112A (en) * | 1995-04-27 | 1998-05-26 | The Procter & Gamble Company | Carrier substrate treated with high internal water phase inverse emulsion made with an organopolysiloxane-polyoxyalkylene emulsifier |
| US5763332A (en) * | 1996-04-30 | 1998-06-09 | The Procter & Gamble Company | Cleaning articles comprising a polarphobic region and a high internal phase inverse emulsion |
| EP0882446A1 (en) * | 1997-06-02 | 1998-12-09 | Gojo Industries,Inc. | Antimicrobial skin cleansing compositions |
| US5863663A (en) * | 1994-11-09 | 1999-01-26 | The Procter & Gamble Company | Wet-like cleaning wipes and like articles comprising a carrier treated with an emulsion having a continuous lipid phase |
| WO1999011233A1 (en) * | 1997-09-04 | 1999-03-11 | Innoscent Ltd. | Deodorant compositions and method |
| US5908707A (en) * | 1996-12-05 | 1999-06-01 | The Procter & Gamble Company | Cleaning articles comprising a high internal phase inverse emulsion and a carrier with controlled absorbency |
| US5948540A (en) * | 1995-04-27 | 1999-09-07 | The Procter & Gamble Company | Carrier substrate treated with high internal phase inverse emulsions made with an organopolysiloxane-polyoxyalkylene emulsifier |
| US5980922A (en) * | 1996-04-30 | 1999-11-09 | Procter & Gamble Company | Cleaning articles treated with a high internal phase inverse emulsion |
| US6133166A (en) * | 1997-07-01 | 2000-10-17 | The Procter & Gamble Company | Cleaning articles comprising a cellulosic fibrous structure having discrete basis weight regions treated with a high internal phase inverse emulsion |
| JP2002348475A (en) * | 2001-05-24 | 2002-12-04 | Ge Toshiba Silicones Co Ltd | Silicone emulsion composition and cosmetic |
| JP2007314494A (en) * | 2006-05-29 | 2007-12-06 | Hideaki Shinkai | Clean-wiping agent |
| WO2012133724A1 (en) * | 2011-03-31 | 2012-10-04 | Unicharm Corporation | Absorbent article |
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| US5863663A (en) * | 1994-11-09 | 1999-01-26 | The Procter & Gamble Company | Wet-like cleaning wipes and like articles comprising a carrier treated with an emulsion having a continuous lipid phase |
| US5756112A (en) * | 1995-04-27 | 1998-05-26 | The Procter & Gamble Company | Carrier substrate treated with high internal water phase inverse emulsion made with an organopolysiloxane-polyoxyalkylene emulsifier |
| US5948540A (en) * | 1995-04-27 | 1999-09-07 | The Procter & Gamble Company | Carrier substrate treated with high internal phase inverse emulsions made with an organopolysiloxane-polyoxyalkylene emulsifier |
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Also Published As
| Publication number | Publication date |
|---|---|
| JPH0720856B2 (en) | 1995-03-08 |
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