JP7085762B2 - 低温スラリ閉じ込め - Google Patents
低温スラリ閉じ込め Download PDFInfo
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- JP7085762B2 JP7085762B2 JP2019554837A JP2019554837A JP7085762B2 JP 7085762 B2 JP7085762 B2 JP 7085762B2 JP 2019554837 A JP2019554837 A JP 2019554837A JP 2019554837 A JP2019554837 A JP 2019554837A JP 7085762 B2 JP7085762 B2 JP 7085762B2
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F2007/0069—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit with return means
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0091—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
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- A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
- A61F2007/025—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability retaining air or other gas
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
- A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
- A61F2007/0253—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability using a substance with low conductivity
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
- A61F2007/0288—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects during operations
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
- A61F2007/029—Fat cell removal or destruction by non-ablative heat treatment
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- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
- A61M2025/1013—Multiple balloon catheters with concentrically mounted balloons, e.g. being independently inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1072—Balloon catheters with special features or adapted for special applications having balloons with two or more compartments
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Description
本願は、2017年4月5日に出願された米国仮出願第62/482,008号の35 U.S.C.§119(e)のもとでの利益を主張するものであり、該米国仮出願の全体の開示は、参照により本明細書中に援用される。
例えば、本願は以下の項目を提供する。
(項目1)
組織温度を制御するためのデバイスであって、前記デバイスは、
第1のカニューレであって、前記第1のカニューレは、患者の皮膚の下の標的組織に低温スラリを送達し、それによって、前記標的組織を冷却するためのものであり、前記第1のカニューレは、第1の開放遠位端と、低温スラリ源と流体連通している第1の近位端とを備える、第1のカニューレと、
第2のカニューレであって、前記第2のカニューレは、第2の開放遠位端と、熱絶縁体源と流体連通している第2の近位端とを備える、第2のカニューレと、
バルーンであって、前記バルーンは、前記第2のカニューレの第2の開放遠位端の周囲に配置され、前記標的組織を囲繞する組織またはその近傍に位置付けられ、前記バルーンは、前記第2のカニューレを通して送達される熱絶縁体で充填される容積を備え、前記充填されるバルーンは、熱が前記囲繞組織から前記標的組織に伝達することを制限する、バルーンと
を備える、デバイス。
(項目2)
前記バルーンは、前記標的組織に面する第1のチャンバと、前記囲繞組織に面する第2のチャンバとを含み、
前記第1のチャンバは、前記第1の開放遠位端と流体連通し、前記第1のカニューレを通して送達される低温スラリで充填され、
前記第2のチャンバは、前記第2の開放遠位端と流体連通し、前記第2のカニューレを通して送達される前記熱絶縁体で充填される、項目1に記載のデバイス。
(項目3)
前記バルーンは、第2のバルーンであり、
前記第1のカニューレの第1の開放遠位端の周囲に配置される第1のバルーンであって、前記第1のバルーンは、前記第1のカニューレを通して送達される前記低温スラリを受容するための容積を備える、第1のバルーン
をさらに備える、項目1に記載のデバイス。
(項目4)
前記第1のバルーンは、独立して前記低温スラリで充填される複数の区画を含む、項目3に記載のデバイス。
(項目5)
前記第1のバルーンは、複数の突出アームを含む、項目3に記載のデバイス。
(項目6)
前記第1のバルーンは、その幅を上回る長さを有する、項目3に記載のデバイス。
(項目7)
前記第1のカニューレの第1の開放遠位端の周囲に配置される内側バルーンであって、前記内側バルーンは、外部表面と、前記第1のカニューレを通して送達される前記低温スラリを受容するための容積とを備える、内側バルーン
をさらに備え、
前記バルーンは、内部表面を備える外側バルーンであり、
前記内側バルーンの外部表面および前記外側バルーンの内部表面は、前記熱絶縁体が充填し、前記囲繞組織から前記標的組織への熱伝達を制限するための空間を形成する、項目1に記載のデバイス。
(項目8)
前記第1のカニューレは、前記第1の開放遠位端と前記第1の近位端との間に延在する第1の縦軸を含み、
前記第2のカニューレは、前記第2の開放遠位端と前記第2の近位端との間に延在する第2の縦軸を含み、前記第2の縦軸は、前記第1の縦軸と整合される、項目7に記載のデバイス。
(項目9)
前記第1の縦軸および第2の縦軸は、同一である、項目8に記載のデバイス。
(項目10)
前記第1および第2のカニューレはそれぞれ、対象の皮膚を通して挿入するために適したサイズおよび形状を有する、項目1に記載のデバイス。
(項目11)
前記第1の開放遠位端を越えて延在し、前記送達される低温スラリの温度を測定する低温スラリ温度モニタをさらに備える、項目1に記載のデバイス。
(項目12)
前記低温スラリ温度モニタは、前記低温スラリ温度モニタの遠位端に温度センサを含む、項目11に記載のデバイス。
(項目13)
前記温度センサは、前方赤外線(FIR)センサである、項目12に記載のデバイス。
(項目14)
前記低温スラリ温度モニタは、前記低温スラリ温度モニタの長さに沿って離間される複数の温度センサを含む、項目11に記載のデバイス。
(項目15)
前記熱絶縁体は、流体、ガス、空気、ゲル、およびエアロゲルのうちのいずれか1つである、項目1に記載のデバイス。
(項目16)
前記低温スラリは、水およびグリセリンの混合物である、項目1に記載のデバイス。
(項目17)
前記バルーンは、その幅を上回る長さを有する、項目1に記載のデバイス。
(項目18)
前記バルーンは、略球形である、項目1に記載のデバイス。
(項目19)
前記バルーンは、縦軸を有しており、かつ、前記縦軸に平行でありそれからオフセットされる線に沿った点によって画定されるようにくぼんでいる、項目1に記載のデバイス。
(項目20)
ガイドであって、前記ガイドは、前記第2のカニューレを収容するようにサイズ決めされる作業チャネルと、前記第2のカニューレの周囲に配置される前記バルーンとを備える、ガイド
をさらに備え、
前記バルーンは、使用時、前記作業チャネルから展開される、項目1に記載のデバイス。
(項目21)
組織温度を制御するためのデバイスであって、前記デバイスは、
患者の皮膚の下の標的組織に低温スラリを送達し、それによって、前記標的組織を冷却するための有窓カニューレであって、前記カニューレは、遠位端と、低温スラリ源と流体連通している近位端とにおいて、複数の開口部を備える、有窓カニューレと、
複数のバルーンであって、各バルーンは、前記複数の開口部のうちの1つの中に配置され、前記低温スラリ源からの低温スラリに暴露されると、膨張し、それによって、前記カニューレの遠位端において、前記標的組織から前記低温スラリへの熱伝達のための表面積の増加を提供するように構成される、複数のバルーンと
を備える、デバイス。
(項目22)
前記複数の開口部のうちの1つ以上のものは、膨張されると、その中に配置される前記複数のバルーンに形状を付与するように構成される、項目21に記載のデバイス。
(項目23)
前記形状は、複数の膨張された部材を含む、項目22に記載のデバイス。
(項目24)
前記形状は、卵形を含む、項目22に記載のデバイス。
(項目25)
前記形状は、球体を含む、項目22に記載のデバイス。
(項目26)
前記複数のバルーンのうちの1つ以上のものは、異なる弾性の2つ以上の面積を含む、項目22に記載のデバイス。
(項目27)
有窓カニューレのアレイを備える、項目21に記載のデバイス。
Claims (19)
- 組織温度を制御するためのデバイスであって、前記デバイスは、
対象の皮膚の下の標的組織に低温スラリを直接送達し、これにより、前記標的組織を冷却するための第1のカニューレであって、前記第1のカニューレは、第1の開放遠位端と、低温スラリの供給源と流体連通している第1の近位端とを備える、第1のカニューレと、
第2の開放遠位端と、熱絶縁体の供給源と流体連通している第2の近位端とを備える第2のカニューレと、
前記第2のカニューレの前記第2の開放遠位端の周囲に配置されているバルーンであって、前記バルーンは、前記標的組織を囲繞する組織または前記標的組織を囲繞する組織の近傍に位置付けられており、前記バルーンは、容積を有し、前記容積は、前記熱絶縁体で充填されており、前記容積を充填する前記熱絶縁体は、前記第2のカニューレを通して前記容積に送達され、前記充填されたバルーンは、熱が前記囲繞組織から前記標的組織に伝達することを制限する、バルーンと
を備える、デバイス。 - 前記第1のカニューレおよび前記第2のカニューレは、前記対象の皮膚を通して挿入可能であるように構成されている、請求項1に記載のデバイス。
- 前記デバイスは、低温スラリ温度モニタをさらに備え、前記低温スラリ温度モニタは、 前記送達される低温スラリの温度を測定するために前記第1の開放遠位端を越えて延在する、請求項1に記載のデバイス。
- 前記低温スラリ温度モニタは、前記低温スラリ温度モニタの遠位端に温度センサを含む、請求項3に記載のデバイス。
- 前記温度センサは、前方赤外線(FIR)センサである、請求項4に記載のデバイス。
- 前記低温スラリ温度モニタは、前記低温スラリ温度モニタの長さに沿って離間されている複数の温度センサを含む、請求項3に記載のデバイス。
- 前記熱絶縁体は、流体、ガス、空気、ゲル、エアロゲルのうちのいずれか1つである、請求項1に記載のデバイス。
- 前記低温スラリは、水およびグリセリンの混合物である、請求項1に記載のデバイス。
- 前記バルーンは、その幅よりも大きい長さを有する、請求項1に記載のデバイス。
- 前記バルーンは、略球形である、請求項1に記載のデバイス。
- 前記バルーンは、縦軸を有し、前記バルーンは、前記バルーンの縦軸に平行である想像線の周りでくぼんでいる、請求項1に記載のデバイス。
- 前記デバイスは、ガイドをさらに備え、前記ガイドは、前記第2のカニューレを収容するようにサイズ決めされているチャネルと、前記第2のカニューレの周囲に配置されている前記バルーンとを備え、
前記バルーンは、使用時、前記チャネルから展開され、
前記ガイドは、前記ガイドの前記チャネルが前記バルーンの機能を制御するように、前記バルーンを案内するように構成されている、請求項1に記載のデバイス。 - 前記バルーンは、線形形状を有する、請求項1に記載のデバイス。
- 前記バルーンは、リング形状を有する、請求項1に記載のデバイス。
- 前記第2のカニューレは、前記対象の皮膚を通して挿入可能であるように構成されている、請求項1に記載のデバイス。
- 前記バルーンは、前記バルーンから外向きに突出する複数のアームを有する、請求項1に記載のデバイス。
- 前記バルーンは、前記バルーンの形状を制御するために開放または閉鎖されることが可能な複数のチャンバを有する、請求項1に記載のデバイス。
- 前記バルーンは、複数のチャンバを有し、前記複数のチャンバのそれぞれは、ガスまたは流体で充填されている、請求項1に記載のデバイス。
- 前記バルーンの前記複数のチャンバのそれぞれにおけるガスまたは流体の温度は異なっている、請求項17に記載のデバイス。
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SG11201909305PA (en) | 2019-11-28 |
WO2018187581A1 (en) | 2018-10-11 |
KR20200015889A (ko) | 2020-02-13 |
BR112019020969A8 (pt) | 2022-11-16 |
ZA201907137B (en) | 2024-02-28 |
MX2019011996A (es) | 2020-01-20 |
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