JP7020656B2 - 組織因子を標的とする抗体、その調製方法及びその使用 - Google Patents
組織因子を標的とする抗体、その調製方法及びその使用 Download PDFInfo
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- JP7020656B2 JP7020656B2 JP2019511436A JP2019511436A JP7020656B2 JP 7020656 B2 JP7020656 B2 JP 7020656B2 JP 2019511436 A JP2019511436 A JP 2019511436A JP 2019511436 A JP2019511436 A JP 2019511436A JP 7020656 B2 JP7020656 B2 JP 7020656B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2021191925A JP2022031296A (ja) | 2015-08-20 | 2021-11-26 | 組織因子を標的とする抗体、その調製方法及びその使用 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510513003 | 2015-08-20 | ||
CN201610705557.4 | 2016-08-22 | ||
CN201610705557.4A CN106467574B (zh) | 2015-08-20 | 2016-08-22 | 靶向于组织因子的抗体、其制备方法和用途 |
PCT/CN2017/074163 WO2018036117A1 (fr) | 2016-08-22 | 2017-02-20 | Anticorps ciblant le facteur tissulaire, son procédé de préparation et son utilisation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021191925A Division JP2022031296A (ja) | 2015-08-20 | 2021-11-26 | 組織因子を標的とする抗体、その調製方法及びその使用 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2019526256A JP2019526256A (ja) | 2019-09-19 |
JP7020656B2 true JP7020656B2 (ja) | 2022-02-16 |
Family
ID=58051968
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019511436A Active JP7020656B2 (ja) | 2015-08-20 | 2017-02-20 | 組織因子を標的とする抗体、その調製方法及びその使用 |
JP2021191925A Pending JP2022031296A (ja) | 2015-08-20 | 2021-11-26 | 組織因子を標的とする抗体、その調製方法及びその使用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021191925A Pending JP2022031296A (ja) | 2015-08-20 | 2021-11-26 | 組織因子を標的とする抗体、その調製方法及びその使用 |
Country Status (3)
Country | Link |
---|---|
JP (2) | JP7020656B2 (fr) |
CN (1) | CN106467574B (fr) |
WO (1) | WO2017028823A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3502141A4 (fr) * | 2016-08-22 | 2020-04-08 | Fudan University | Anticorps ciblant le facteur tissulaire, son procédé de préparation et son utilisation |
CN106938051B (zh) * | 2016-08-22 | 2019-10-11 | 复旦大学 | 靶向于组织因子的抗体-药物偶联物 |
CN110240654A (zh) * | 2018-03-07 | 2019-09-17 | 复旦大学 | 结合cd73的抗体-药物偶联物 |
CN110483639A (zh) * | 2018-05-15 | 2019-11-22 | 复旦大学 | 靶向axl的抗体及抗体-药物偶联物及其制备方法和用途 |
CN112442132A (zh) * | 2019-09-05 | 2021-03-05 | 复旦大学 | 靶向肿瘤的重组双功能融合蛋白及其应用 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005512970A (ja) | 2001-10-02 | 2005-05-12 | ノボ ノルディスク アクティーゼルスカブ | ヒト組織因子抗体 |
JP2010525820A (ja) | 2007-04-30 | 2010-07-29 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 増強されたエフェクター機能を有する、抗組織因子抗体及び組成物 |
JP2013532148A (ja) | 2010-06-15 | 2013-08-15 | ゲンマブ エー/エス | 組織因子に対するヒト抗体薬物結合体 |
CN103342752A (zh) | 2013-05-16 | 2013-10-09 | 太原博奥特生物技术有限公司 | 一种抗人组织因子单链抗体及其制备方法 |
US20140079628A1 (en) | 2003-05-30 | 2014-03-20 | G. Mark Anderson | Anti-tissue factor antibodies and compositions |
JP2014509856A (ja) | 2011-03-15 | 2014-04-24 | ヤンセン バイオテツク,インコーポレーテツド | ヒト組織因子抗体及びその使用 |
JP2015511314A (ja) | 2012-02-03 | 2015-04-16 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 分子診断試験の分布及び試験間のコンパチビリティ判断のための外部ファイル |
WO2015115656A1 (fr) | 2014-02-03 | 2015-08-06 | 独立行政法人国立がん研究センター | Anticorps monoclonal anti-facteur tissulaire |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA109633C2 (uk) * | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора |
-
2016
- 2016-08-22 CN CN201610705557.4A patent/CN106467574B/zh active Active
- 2016-08-22 WO PCT/CN2016/096291 patent/WO2017028823A1/fr active Application Filing
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2017
- 2017-02-20 JP JP2019511436A patent/JP7020656B2/ja active Active
-
2021
- 2021-11-26 JP JP2021191925A patent/JP2022031296A/ja active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005512970A (ja) | 2001-10-02 | 2005-05-12 | ノボ ノルディスク アクティーゼルスカブ | ヒト組織因子抗体 |
US20140079628A1 (en) | 2003-05-30 | 2014-03-20 | G. Mark Anderson | Anti-tissue factor antibodies and compositions |
JP2010525820A (ja) | 2007-04-30 | 2010-07-29 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 増強されたエフェクター機能を有する、抗組織因子抗体及び組成物 |
JP2013532148A (ja) | 2010-06-15 | 2013-08-15 | ゲンマブ エー/エス | 組織因子に対するヒト抗体薬物結合体 |
JP2014509856A (ja) | 2011-03-15 | 2014-04-24 | ヤンセン バイオテツク,インコーポレーテツド | ヒト組織因子抗体及びその使用 |
JP2015511314A (ja) | 2012-02-03 | 2015-04-16 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 分子診断試験の分布及び試験間のコンパチビリティ判断のための外部ファイル |
CN103342752A (zh) | 2013-05-16 | 2013-10-09 | 太原博奥特生物技术有限公司 | 一种抗人组织因子单链抗体及其制备方法 |
WO2015115656A1 (fr) | 2014-02-03 | 2015-08-06 | 独立行政法人国立がん研究センター | Anticorps monoclonal anti-facteur tissulaire |
Also Published As
Publication number | Publication date |
---|---|
CN106467574B (zh) | 2019-09-20 |
WO2017028823A1 (fr) | 2017-02-23 |
JP2019526256A (ja) | 2019-09-19 |
CN106467574A (zh) | 2017-03-01 |
JP2022031296A (ja) | 2022-02-18 |
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