JP6869312B2 - ラクトバチルスファーメンタムgkf3、それを含む組成物及び精神失調を改善する適用 - Google Patents
ラクトバチルスファーメンタムgkf3、それを含む組成物及び精神失調を改善する適用 Download PDFInfo
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- JP6869312B2 JP6869312B2 JP2019209593A JP2019209593A JP6869312B2 JP 6869312 B2 JP6869312 B2 JP 6869312B2 JP 2019209593 A JP2019209593 A JP 2019209593A JP 2019209593 A JP2019209593 A JP 2019209593A JP 6869312 B2 JP6869312 B2 JP 6869312B2
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Description
ラクトバチルスファーメンタムGKF3コロニー(colony)を取って液体培地に接種して液体培養を行う工程(a)と、
工程(a)で培養されたコロニーからなる菌体を含む前記液体培地に対して発酵培養を行って、発酵全液を得る工程(b)と、
で調製される。
工程(b)で培養された発酵全液を遠心分離して、菌泥を得る工程(c)と、
工程(c)で得られた菌泥を凍結乾燥する工程(d)と、
で調製される。
マウスへの毎日の経管給餌分量(g)
={成人の毎日の分量/60kg(成人体重)}
×マウス体重(kg)×12.3(マウスと人の換算係数) (I)
[寄託菌株]
Claims (8)
- 2018年01月12日に中国一般微生物株保存管理センター(CGMCC)(連絡先:中国・北京・中国科学院微生物研究所;郵便番号:100101;受託番号:CGMCC No.15203)に寄託されるラクトバチルスファーメンタム(Lactobacillus fermentum)GKF3であって、耐熱性を有し、ドーパミン含有量及びセロトニン含有量の向上のために使用される、ラクトバチルスファーメンタムGKF3。
- 前記ラクトバチルスファーメンタムGKF3は、耐酸性及び/又は胆汁酸塩耐性を有する請求項1に記載のラクトバチルスファーメンタムGKF3。
- 2018年01月12日に中国一般微生物株保存管理センター(CGMCC)(連絡先:中国・北京・中国科学院微生物研究所;郵便番号:100101;受託番号:CGMCC No.15203)に寄託されるラクトバチルスファーメンタム(Lactobacillus fermentum)GKF3を含む、精神失調を改善するための組成物であって、前記ラクトバチルスファーメンタムGKF3は、耐熱性を有し、ドーパミン含有量及びセロトニン含有量の向上のために使用される、組成物。
- 前記組成物は、賦形剤、防腐剤、希釈剤、充填剤、吸収促進剤、甘味剤又はそれらの組み合わせの群から選ばれる1つ以上の添加剤を含む請求項3に記載の組成物。
- 前記組成物は、医薬品、飼料、飲料、栄養補助食品、乳製品、高齢者向け食品、離乳食、副食品又は健康食品である請求項3に記載の組成物。
- 前記組成物の形態は、粉剤、錠剤、造粒、坐剤、マイクロカプセル、アンプル、液剤、スプレー剤又は座薬である請求項3に記載の組成物。
- 前記精神失調の症状は、不眠症、自律神経障害、集中力低下、うつ病又はそれらの組み合わせを含む請求項3から6の何れか1項に記載の組成物。
- 請求項1又は2のラクトバチルスファーメンタムGKF3を含む、ドーパミン含有量及びセロトニン含有量の向上のための組成物であって、被検者に投与されると、前記ラクトバチルスファーメンタムGKF3は、被投与者の脳組織におけるドーパミン含有量及びセロトニン含有量を向上する、組成物。
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