JP6539044B2 - 乳ベース製剤 - Google Patents
乳ベース製剤 Download PDFInfo
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- JP6539044B2 JP6539044B2 JP2014517855A JP2014517855A JP6539044B2 JP 6539044 B2 JP6539044 B2 JP 6539044B2 JP 2014517855 A JP2014517855 A JP 2014517855A JP 2014517855 A JP2014517855 A JP 2014517855A JP 6539044 B2 JP6539044 B2 JP 6539044B2
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- 239000000203 mixture Substances 0.000 title claims description 58
- 238000009472 formulation Methods 0.000 title claims description 40
- 230000002829 reductive effect Effects 0.000 claims description 102
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 69
- 239000008101 lactose Substances 0.000 claims description 69
- 239000000843 powder Substances 0.000 claims description 61
- 102000004169 proteins and genes Human genes 0.000 claims description 48
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- YQHPCDPFXQXCMV-VIFPVBQESA-N (2s)-2-amino-6-[[2-(furan-2-yl)-2-oxoethyl]amino]hexanoic acid Chemical compound OC(=O)[C@@H](N)CCCCNCC(=O)C1=CC=CO1 YQHPCDPFXQXCMV-VIFPVBQESA-N 0.000 description 8
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- 102100026189 Beta-galactosidase Human genes 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 239000003729 cation exchange resin Substances 0.000 description 3
- 235000013351 cheese Nutrition 0.000 description 3
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- CXTMLIMZRPKULL-YXYYPBJFSA-N dnc013643 Chemical compound O([C@@H]1O[C@@H]([C@H]2OC(=O)C=3[C@@H]4C(C(C(=O)C=3)(O)O)(O)OC=3C(O)=C(O)C=C(C4=3)C(=O)O[C@@H]1[C@H]2O)CO)C(=O)C1=CC(O)=C(O)C(O)=C1 CXTMLIMZRPKULL-YXYYPBJFSA-N 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
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- 229930182830 galactose Natural products 0.000 description 3
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- 241000283690 Bos taurus Species 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
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- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 2
- 239000004472 Lysine Substances 0.000 description 2
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- 150000002772 monosaccharides Chemical class 0.000 description 2
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- UOQHWNPVNXSDDO-UHFFFAOYSA-N 3-bromoimidazo[1,2-a]pyridine-6-carbonitrile Chemical compound C1=CC(C#N)=CN2C(Br)=CN=C21 UOQHWNPVNXSDDO-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
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- 241000283707 Capra Species 0.000 description 1
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
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- 150000001413 amino acids Chemical class 0.000 description 1
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- 235000014121 butter Nutrition 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000019869 fractionated palm oil Nutrition 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 1
- 229960003451 lactitol Drugs 0.000 description 1
- 235000010448 lactitol Nutrition 0.000 description 1
- 239000000832 lactitol Substances 0.000 description 1
- 229940099563 lactobionic acid Drugs 0.000 description 1
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 1
- 229960000511 lactulose Drugs 0.000 description 1
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 235000020121 low-fat milk Nutrition 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 235000020184 organic milk Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 235000020201 recombined milk Nutrition 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000006098 transglycosylation Effects 0.000 description 1
- 238000005918 transglycosylation reaction Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/18—Milk in dried and compressed or semi-solid form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/005—Condensed milk; Sugared condensed milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
- A23C9/1206—Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1427—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by dialysis, reverse osmosis or hyperfiltration, e.g. for concentrating or desalting
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/146—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by ion-exchange
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/15—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/15—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins
- A23C9/1508—Dissolving or reconstituting milk powder; Reconstitution of milk concentrate with water; Standardisation of fat content of milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/25—Separating and blending
- A23C2210/252—Separating a milk product in at least two fractions followed by treatment of at least one of the fractions and remixing at least part of the two fractions
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Water Supply & Treatment (AREA)
- Microbiology (AREA)
- Dairy Products (AREA)
- Non-Alcoholic Beverages (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Description
本発明は乳ベース製剤(milk−based formulation)に関する。より具体的に、本発明は炭水化物含量が低減された還元乳(recombined milk)の調製に好適な乳ベース製剤に関する。
粉乳および水を還元する(recombining)ことにより調製される還元乳飲料は通常の乳に比べていくつかの欠点を有することが知られている。欠点は、特に乳糖含量を低減した還元乳飲料の調製の際に現れる。欠点は、事実上官能的および栄養的の両方である。例えば、還元乳飲料は加熱処理の間、および特に飲料の保存の間に沈殿/沈渣を形成しやすい。沈殿物は、主に乳タンパク質で構成される。乳タンパク質のうち、乳清タンパク質が非常に熱感受性であることが知られている。いくつかのミネラルもまた、還元乳飲料の沈殿事象に影響を与え得る。現在、還元乳製品の沈殿の感受性、凝集に関連する問題は、製品に安定剤のような添加物を用いることで回避されている。
ここで、低減された炭水化物含量をもち、通常の乳の良好な風味を有し、さらに類似の従来の製品に関する典型的な問題を避ける還元乳製品の調製に好適な乳ベース製剤が見出された。還元乳製品は官能特性、特に風味において完全に欠点がない。
a)乳原料の成分をタンパク質画分、炭水化物画分およびミネラル画分に分離する、
b)タンパク質画分の少なくとも一部分およびミネラル画分の少なくとも一部分を組み合わせて、乳ベース製剤を提供する、
工程を含む乳ベース製剤の製造方法を提供する。
本明細書で用いられる「還元乳製品」なる用語は、乳ベースの製剤を液体で還元することにより調製される乳製品を意味する。乳脂(クリーム、バター)の様なさらなる原料を、製品の所望の脂肪分を得るために還元乳製品に組み込むことができる。製剤はまた所望の脂肪、タンパク質およびミネラル含量で調製できる。
a)乳原料の成分をタンパク質画分、炭水化物画分およびミネラル画分に分離する、
b)タンパク質画分の少なくとも一部分およびミネラル画分の少なくとも一部分を組み合わせて、乳ベース製剤を提供する、
工程を含む、低減された炭水化物含量の、本発明の乳ベース製剤の製造方法を提供する。。
脱脂乳をGR61PP膜(Dow、米国)で10℃の温度、濃縮係数4で限外ろ過し、限外濾過(UF)透過液および限外濾過(UF)保持液を得た。UF透過液をさらにDesal DK膜(Osmonics、米国)で10℃〜15℃の温度、濃縮係数4でナノろ過し、ナノろ過(NF)透過液およびナノろ過(NF)保持液を得た。NF透過液をFilmtec RO−390−FF膜(Dow、米国)での濃縮係数10の逆浸透(RO)により濃縮し、RO透過液およびRO保持液を提供した。
脱脂乳を濃縮係数が1.6であることを除いて実施例1に記載のとおりに限外ろ過し、UF保持液を得た。
脱脂乳を蒸発させ乾物含量30%の乳濃縮物を得た。乳濃縮物を、陽イオン交換樹脂を充填したクロマトグラフィーカラムにポンプ輸送した。陽イオン交換樹脂を通して溶出した脱脂乳を、乳ミネラルおよびタンパク質の大部分が同じ画分になるように回収した。画分の回収が終了するとき、乳糖の大部分はクロマトグラフィーカラムにまだ残っていた。クロマトグラフィーによる分離は約60℃の温度で実施した。
さまざまな乳飲料を実施例1〜3で得られた画分および粉末から調製した。具体的な配合は表7に示す。数値は配合中の各々の画分の百分率を示す。
である。本発明およびその実施態様は、上述した例示に限定されるものではなく、特許請
求の範囲内において様々に変更することができる。
Claims (25)
- 乳糖のタンパク質に対する比が少なくとも0.02および最大で1.1であり、乾量基準で少なくとも45%のタンパク質含量を有し、灰分のタンパク質に対する比が、開始原料として使用される乳原料における元の灰分のタンパク質に対する比である、乳糖含量が低減された乳ベース粉末(アルコール発酵を経て製造されたものを除く)の、低減された乳糖含量をもつ還元乳製品の調製への使用。
- 乳糖のタンパク質に対する比が最大で0.9である、請求項1に記載の使用。
- 乳糖のタンパク質に対する比が最大で0.4である、請求項2に記載の使用。
- 一価ミネラルのタンパク質に対する比が、開始原料として使用される乳原料における元の一価ミネラルのタンパク質に対する比である、請求項1〜3のいずれか一項に記載の使用。
- 無脂全固形分換算で、45〜65%のタンパク質、4.6〜41%の乳糖、および1.0〜14%の灰分を含む、請求項1〜4のいずれか一項に記載の使用。
- 無脂全固形分換算で、48〜60%のタンパク質、24〜43%の乳糖、および10〜13%の灰分を含む、請求項1〜4のいずれか一項に記載の使用。
- 乳ベース粉末が、乳原料から乳糖を除去して、乳糖含量が低減された乳ベース製剤を得ること、および乳ベース製剤を濃縮して粉末とすることを含む方法で製造されたものである、請求項1〜6のいずれか一項に記載の使用。
- 乳糖の除去が、クロマトグラフィー、沈殿、膜ろ過技術またはそれらの組み合わせによる手段で実施される、請求項7に記載の使用。
- 方法が、
a)乳原料の成分をタンパク質画分、乳糖画分およびミネラル画分に分離する、
b)タンパク質画分の少なくとも一部分およびミネラル画分の少なくとも一部分を組み合わせて、乳ベース製剤を得る、
工程を含む、請求項7に記載の、使用。 - 分離が限外ろ過、ナノろ過および逆浸透により達成される、請求項9に記載の使用。
- 乳原料が限外ろ過(UF)に供されてUF透過液、およびUF保持液としてのタンパク質画分を得る、請求項10に記載の使用。
- 限外ろ過透過液がナノろ過(NF)に供されてNF透過液、およびNF保持液としての乳糖画分を得て、NF透過液が逆浸透(RO)に供されてRO保持液としてのミネラル画分を得る、請求項11に記載の使用。
- タンパク質画分およびミネラル画分が、乳原料のクロマトグラフィー分離に由来する、請求項9に記載の使用。
- タンパク質画分およびミネラル画分の一つまたは両方が少なくとも17%の乾物含量に濃縮される、請求項9〜13のいずれか一項に記載の使用。
- 乳ベース粉末の乳糖含量が16.3〜40.9重量%である、請求項1〜14のいずれか一項に記載の使用。
- 還元乳製品が乳飲料である、請求項1〜15のいずれか一項に記載の使用。
- 還元乳製品中の粉乳の量が0.5〜15重量%である、請求項1〜16のいずれか一項に記載の使用。
- 還元乳製品中の粉乳の量が2〜7重量%である、請求項17に記載の使用。
- 乳糖のタンパク質に対する比が少なくとも0.02および最大で1.1であり、乾量基準で少なくとも45%のタンパク質含量を有し、灰分のタンパク質に対する比が、開始原料として使用される乳原料における元の灰分のタンパク質に対する比である、乳糖含量が低減された乳ベース粉末(アルコール発酵を経て製造されたものを除く)、を液体および任意の他の原料で還元し、低減された乳糖含量をもつ還元乳を提供することを含む、低減された乳糖含量をもつ還元乳製品を製造する方法。
- 還元乳が飲料である、請求項19に記載の方法。
- 還元乳製品の乳糖含量が最大で3.1重量%である、請求項19または20に記載の方法。
- 還元乳製品が熱処理に供される、請求項19〜21のいずれか一項に記載の方法。
- 還元乳製品の残余の乳糖が加水分解される、請求項19〜22のいずれか一項に記載の方法。
- 還元乳製品の残余の乳糖が熱処理後に加水分解される、請求項23に記載の方法。
- 還元乳製品の官能特性が脱脂乳のものと同等である、請求項19〜24のいずれか一項に記載の方法。
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US11503836B2 (en) | 2020-10-20 | 2022-11-22 | Michael J. McCloskey | Process for making lactose-free milk powders |
FI20215073A1 (en) | 2021-01-21 | 2022-07-22 | Valio Oy | Milk powder composition |
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