JP6297706B2 - 改変された流路を形成する熱交換器コアを有する血液処理ユニット - Google Patents
改変された流路を形成する熱交換器コアを有する血液処理ユニット Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1629—Constructional aspects thereof with integral heat exchanger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3623—Means for actively controlling temperature of blood
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
- F28D21/00—Heat-exchange apparatus not covered by any of the groups F28D1/00 - F28D20/00
- F28D21/0015—Heat and mass exchangers, e.g. with permeable walls
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
- F28D7/00—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
- F28D7/10—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits being arranged one within the other, e.g. concentrically
- F28D7/103—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits being arranged one within the other, e.g. concentrically consisting of more than two coaxial conduits or modules of more than two coaxial conduits
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
- F28F13/00—Arrangements for modifying heat-transfer, e.g. increasing, decreasing
- F28F13/06—Arrangements for modifying heat-transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media
- F28F13/12—Arrangements for modifying heat-transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media by creating turbulence, e.g. by stirring, by increasing the force of circulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/12—Flow characteristics the flow being spirally in a plane, e.g. against a plane side of a membrane filter element
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/20—Specific housing
- B01D2313/203—Open housings
- B01D2313/2031—Frame or cage-like structures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/22—Cooling or heating elements
- B01D2313/221—Heat exchangers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/23—Specific membrane protectors, e.g. sleeves or screens
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
- F28D21/00—Heat-exchange apparatus not covered by any of the groups F28D1/00 - F28D20/00
- F28D2021/0019—Other heat exchangers for particular applications; Heat exchange systems not otherwise provided for
- F28D2021/005—Other heat exchangers for particular applications; Heat exchange systems not otherwise provided for for medical applications
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- General Engineering & Computer Science (AREA)
- Thermal Sciences (AREA)
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- External Artificial Organs (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
Description
Claims (8)
- 血液処理装置であって、
血液入口と、血液出口とを有する筐体であって、前記血液入口が前記筐体の第1の端部の近くで前記筐体の内部に延在する、筐体と、
前記筐体内に配設された熱交換器コアであって、前記血液入口からコア開口部を通って前記熱交換器コアの外へ進む血液に径方向の流れを加えるように構成され、陥凹部を規定する1つまたは複数のリブを含む熱交換器コアと、
熱交換中空繊維であって、熱交換流体が前記熱交換中空繊維を通って流れることができ且つコア開口部からの血液が前記熱交換中空繊維を横断して流れることができるように、前記熱交換器コアの周りに配置され、前記熱交換器コアの前記1つまたは複数のリブにより支持された熱交換中空繊維と、
前記熱交換器コアの周りに同軸に延在する円筒形のシェルであって、前記筐体の第2の端部の近くに配置された環状のシェル開口部を含み、前記シェル開口部が、前記円筒形のシェルの外へ進む血液に長手方向の血流成分を加えるように構成される、円筒形のシェルと、
ガス交換中空繊維であって、ガスが前記ガス交換中空繊維を通って流れることができ且つ前記環状のシェル開口部から通じる血液が前記ガス交換中空繊維を横断して流れることができるように、前記円筒形のシェルの周りに配置されたガス交換中空繊維と
を備え、
前記熱交換器コアが血液乱流区分を含み、
前記血液乱流区分は、前記熱交換器コアの外面内に形成された凹部と、前記凹部に配置された格子とを備え、前記格子が、前記格子を通って延在する複数の開口部を備える血液処理装置。 - 前記1つまたは複数のリブが、前記熱交換中空繊維を支持し、前記熱交換中空繊維を横断する血流に径方向の成分を提供するように構成された1つまたは複数の径方向に配置されたコアリブを含む、請求項1に記載の血液処理装置。
- 前記熱交換器コアは、前記血液入口と前記コア開口部との間に配置された円錐偏向面を含み、前記円錐偏向面が、前記コア開口部を離れる血流の軌道に径方向の成分を加える、請求項1に記載の血液処理装置。
- 前記筐体が内面を含み、その上に1つまたは複数の径方向に配置された筐体リブが配置され、前記1つまたは複数の径方向に配置された筐体リブは、前記ガス交換中空繊維を横断する血流の軌道に径方向の成分を加えるように構成される、請求項1に記載の血液処理
装置。 - 前記筐体に固定された第1の端部キャップをさらに備え、前記血液入口が、前記第1の端部キャップと一体的に形成される、請求項1に記載の血液処理装置。
- 前記第1の端部キャップと一体的に形成されたガス入口をさらに備え、前記ガス入口は、前記ガス交換中空繊維の内部と流体連通する、請求項5に記載の血液処理装置。
- 前記筐体に固定された第2の端部キャップをさらに備え、前記第2の端部キャップが、前記第2の端部キャップと一体的に形成された熱交換流体入口と、前記第2の端部キャップと一体的に形成された熱交換流体出口とを含み、前記熱交換流体入口および前記熱交換流体出口はそれぞれ、前記熱交換中空繊維の内部と流体連通する、請求項1に記載の血液処理装置。
- 前記第2の端部キャップと一体的に形成されたガス出口をさらに備え、前記ガス出口は、前記ガス交換中空繊維の内部と流体連通する、請求項7に記載の血液処理装置。
Applications Claiming Priority (1)
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PCT/IT2014/000005 WO2015104725A1 (en) | 2014-01-09 | 2014-01-09 | Blood processing unit with heat exchanger core for providing modified flow path |
Publications (2)
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JP2017507686A JP2017507686A (ja) | 2017-03-23 |
JP6297706B2 true JP6297706B2 (ja) | 2018-03-20 |
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JP2016545788A Expired - Fee Related JP6297706B2 (ja) | 2014-01-09 | 2014-01-09 | 改変された流路を形成する熱交換器コアを有する血液処理ユニット |
Country Status (5)
Country | Link |
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US (2) | USRE49759E1 (ja) |
EP (1) | EP3092015B1 (ja) |
JP (1) | JP6297706B2 (ja) |
CN (1) | CN105899245B (ja) |
WO (1) | WO2015104725A1 (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2612685B1 (en) | 2010-08-19 | 2014-10-08 | Sorin Group Italia S.r.l. | Blood processing unit with modified flow path |
CN106029118B (zh) | 2014-02-28 | 2018-10-02 | 索林集团意大利有限责任公司 | 用于将集成动脉过滤器设置在氧合器中、使增加的预充量最小化的*** |
JP6490216B2 (ja) | 2014-11-12 | 2019-03-27 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータSorin Group Italia S.r.l. | 中空繊維血液処理装置用の弾性保護管 |
US10661004B2 (en) | 2015-05-12 | 2020-05-26 | Sorin Group Italia S.R.L. | Blood gas exchanger with restriction element or elements to reduce gas exchange |
US11446420B2 (en) * | 2016-11-29 | 2022-09-20 | Gambro Lundia Ab | Connector arrangement, a system for extracorporeal blood treatment and a method for priming a fluid chamber of a blood treatment unit |
CN107362399B (zh) * | 2017-09-12 | 2023-06-13 | 东莞科威医疗器械有限公司 | 一种螺旋导流集成式膜式氧合器 |
CN107432960B (zh) * | 2017-09-12 | 2024-01-09 | 东莞科威医疗器械有限公司 | 一种螺旋导流集成式膜式氧合器 |
EP3694575A1 (en) * | 2017-10-10 | 2020-08-19 | Sorin Group Italia S.r.l. | Blood processing unit (bpu) with countercurrent blood/water flow paths in the heat exchanger (hex) |
WO2019150569A1 (ja) * | 2018-02-05 | 2019-08-08 | テルモ株式会社 | 人工肺及びその製造方法 |
WO2020158777A1 (ja) * | 2019-01-29 | 2020-08-06 | ニプロ株式会社 | 人工肺装置 |
Family Cites Families (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3339341A (en) | 1965-12-22 | 1967-09-05 | Du Pont | Fluid separation process and apparatus |
FR2214502B1 (ja) | 1973-01-18 | 1976-05-14 | Rhone Poulenc Ind | |
FR2231421B1 (ja) | 1973-05-30 | 1976-05-07 | Rhone Poulenc Ind | |
JPS5847373B2 (ja) | 1975-07-29 | 1983-10-21 | 松下電工株式会社 | 長尺絶縁被覆付トロリ−ワイヤ |
JPS52126681A (en) | 1976-04-16 | 1977-10-24 | Asahi Chem Ind Co Ltd | Improved hollow fiber fluid separating apparatus |
SE421999B (sv) | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | Anordning for diffusion och/eller filtration av emnen mellan tva fluider via semipermeabla membran vilken anordning innefattar parallellkopplade banor innehallande seriekopplade kamrar |
IT1091268B (it) | 1977-12-15 | 1985-07-06 | Hospal Dasco Spa | Perfezionamento ad un emodializzatore |
JPS5935631B2 (ja) | 1980-07-24 | 1984-08-29 | テルモ株式会社 | 体液「ろ」過装置 |
US4707268A (en) | 1982-10-18 | 1987-11-17 | Baxter Travenol Laboratories, Inc. | Hollow fiber potted microfilter |
US4902476A (en) | 1983-01-14 | 1990-02-20 | Baxter International Inc. | Heat exchanger and blood oxygenator apparatus |
JPS59147603A (ja) | 1983-02-10 | 1984-08-24 | Kuraray Co Ltd | 保護体付き中空糸束 |
JPS6053156A (ja) | 1983-09-01 | 1985-03-26 | 三菱レイヨン株式会社 | 血液浄化器 |
EP0312125B1 (en) | 1983-11-11 | 1992-03-04 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Device for receiving and treating blood |
CA1251109A (en) | 1984-04-24 | 1989-03-14 | Tohru Takemura | Blood oxygenator using a hollow-fiber membrane |
CA1258436A (en) | 1984-08-01 | 1989-08-15 | Michael A. Smoot | Mat structure for use in filtration devices |
JPS63139562A (ja) | 1986-12-01 | 1988-06-11 | 株式会社 日本メデイカル・サプライ | 中空糸型人工肺 |
US4758341A (en) | 1987-04-20 | 1988-07-19 | The Dow Chemical Company | Membrane separation device |
JPS6440060A (en) | 1987-08-06 | 1989-02-10 | Ube Industries | Artificial lung provided with built-in heat exchanger |
JPS6476868A (en) | 1987-09-18 | 1989-03-22 | Nippon Medical Supply | Improved pump-oxygenator |
US5120501A (en) | 1988-10-20 | 1992-06-09 | Baxter International Inc. | Integrated membrane blood oxygenator/heat exchanger |
US5316724A (en) | 1989-03-31 | 1994-05-31 | Baxter International Inc. | Multiple blood path membrane oxygenator |
JPH0347271A (ja) | 1989-07-14 | 1991-02-28 | Terumo Corp | 液体処理器 |
US5578267A (en) | 1992-05-11 | 1996-11-26 | Minntech Corporation | Cylindrical blood heater/oxygenator |
US5270004A (en) | 1989-10-01 | 1993-12-14 | Minntech Corporation | Cylindrical blood heater/oxygenator |
EP0519132A1 (en) | 1989-10-18 | 1992-12-23 | Exxon Research And Engineering Company | Hollow fiber module |
JPH03169329A (ja) | 1989-11-30 | 1991-07-23 | Nok Corp | 中空糸膜モジュールの製造方法 |
JP3228518B2 (ja) | 1990-12-14 | 2001-11-12 | 日機装株式会社 | 人工心肺装置 |
JPH05177117A (ja) | 1991-10-23 | 1993-07-20 | Hisateru Takano | 物質交換装置 |
JP3284568B2 (ja) | 1991-10-31 | 2002-05-20 | 株式会社ジェイ・エム・エス | 人工肺用入口ヘッダーおよびそれを使用した人工肺 |
US5192439A (en) | 1992-02-03 | 1993-03-09 | Electromedics, Inc. | Blood collection reservoir and filter device |
WO1994003266A1 (en) | 1992-08-03 | 1994-02-17 | Maloney James V Jr | Improved mass and thermal transfer means for use in heart lung machines, dialyzers, and other applications |
IT1255820B (it) * | 1992-08-10 | 1995-11-16 | Nicola Ghelli | Scambiatore di calore in circuito ematico extracorporeo |
US5489413A (en) | 1992-11-03 | 1996-02-06 | Cobe Laboratories, Inc. | Hollow fiber blood oxygenator |
US5501663A (en) | 1993-07-02 | 1996-03-26 | Medtronic Electromedics, Inc. | Inflatable percutaneous oxygenator with transverse hollow fibers |
US5514095A (en) | 1994-04-04 | 1996-05-07 | Haemonetics Corporation | Apparatus for heating, filtering and eliminating gas from biological fluids |
IT1271104B (it) | 1994-11-25 | 1997-05-26 | Dideco Spa | Ossigenatore di sangue con uno strato di capillari in membrana microporosa. |
JPH08168525A (ja) | 1994-12-19 | 1996-07-02 | Terumo Corp | 中空糸膜型血液処理器の製造方法及びその製造装置 |
US5651765A (en) | 1995-04-27 | 1997-07-29 | Avecor Cardiovascular Inc. | Blood filter with concentric pleats and method of use |
WO1997000636A1 (en) | 1995-06-20 | 1997-01-09 | Poeshty K Andrew | Supporting structure to mount and hold cylindrical shaped element |
EP0765683B1 (de) | 1995-09-25 | 1998-07-01 | MEDOS Medizintechnik GmbH | Vorrichtung zur Behandlung von Flüssigkeiten, insbesondere von Blut |
US5770149A (en) | 1995-10-31 | 1998-06-23 | Baxter International | Extracorporeal blood oxygenation system having integrated blood pump, heat exchanger and membrane oxygenator |
US5762868A (en) | 1995-11-30 | 1998-06-09 | Minnesota Mining And Manufacturing Company | Blood oxygenator and heat exchanger |
AU707042B2 (en) | 1996-01-11 | 1999-07-01 | Medtronic, Inc. | Blood oxygenator with heat exchanger |
SE506613C2 (sv) | 1996-05-30 | 1998-01-19 | Votinex Management Sa | Filter- och värmeväxlaranordning |
US5762869A (en) | 1996-07-24 | 1998-06-09 | Gish Biomedical, Inc. | Blood oxygenator |
WO1998022161A1 (fr) | 1996-11-15 | 1998-05-28 | Scitec K.K. | Dialyseur a fibres creuses |
JPH1147268A (ja) | 1997-08-06 | 1999-02-23 | Terumo Corp | 中空糸膜型人工肺 |
US6241945B1 (en) | 1998-03-16 | 2001-06-05 | Life Science Holdings, Inc. | Modular combined pump, filtration, oxygenation and/or debubbler apparatus |
CN1308549A (zh) * | 1998-05-08 | 2001-08-15 | 爱德华兹生命科学公司 | 带有整体热交换器/蓄存器的低灌注膜片充氧器 |
US6113782A (en) | 1998-07-28 | 2000-09-05 | Terumo Cardiovascular Systems Corporation | Potting of tubular bundles in housing |
US6193681B1 (en) | 1998-09-14 | 2001-02-27 | American Immuno Tech, Llc. | Septicemia prevention and treatment system |
JP3992377B2 (ja) | 1998-09-18 | 2007-10-17 | テルモ株式会社 | 熱交換機能内蔵中空糸膜型人工肺 |
US6454999B1 (en) | 1998-12-30 | 2002-09-24 | Cardiovention, Inc. | Integrated blood pump and oxygenator system having extended blood flow path |
JP4041254B2 (ja) | 1999-12-15 | 2008-01-30 | テルモ株式会社 | 中空糸膜型人工肺 |
ATE387950T1 (de) | 2000-03-07 | 2008-03-15 | Mat Adsorption Technologies Gm | Modul mit membranelementen in cross-flow und in dead-end anordnung |
US6459937B1 (en) | 2000-04-25 | 2002-10-01 | Pacesetter, Inc. | Endocardial pacing lead with detachable tip electrode assembly |
IT1318742B1 (it) | 2000-08-08 | 2003-09-10 | Dideco Spa | Dispositivo ossigenatore del sangue in circuito extracorporeo. |
US6730267B2 (en) | 2001-02-09 | 2004-05-04 | Cardiovention, Inc. | Integrated blood handling system having active gas removal system and methods of use |
US6755894B2 (en) | 2001-05-02 | 2004-06-29 | Praxair Technology, Inc. | Hollow fiber membrane gas separation cartridge and gas purification assembly |
US6623638B2 (en) | 2001-06-01 | 2003-09-23 | Baxter International Inc. | Hemodialyzer having improved dialysate perfusion |
HU229432B1 (hu) | 2001-09-25 | 2013-12-30 | Honda Motor Co Ltd | Hõtároló berendezés és eljárás annak gyártására |
CN2511309Y (zh) | 2001-11-16 | 2002-09-18 | 广东省医疗器械研究所 | 膜式氧合器 |
US20030175149A1 (en) | 2002-03-18 | 2003-09-18 | Bruce Searles | Renewable, modifiable, membrane gas exchanger |
JP4214910B2 (ja) | 2002-12-26 | 2009-01-28 | ニプロ株式会社 | 透析器およびその製造方法 |
ATE458511T1 (de) | 2002-12-26 | 2010-03-15 | Nipro Corp | Dialysator und dessen herstellungsverfahren |
JP4337573B2 (ja) | 2004-02-10 | 2009-09-30 | 株式会社ジェイ・エム・エス | 熱交換器、その製造方法及び人工心肺装置 |
DE102004012049B4 (de) | 2004-03-11 | 2006-02-09 | Siemens Ag | Verfahren zum Befestigen eines Blechpaketes für die Statorwicklung eines Linearmotors am Fahrweg |
CN2772515Y (zh) * | 2004-04-23 | 2006-04-19 | 广东省医疗器械研究所 | 一种中空纤维膜式氧合器 |
JP4366268B2 (ja) | 2004-07-23 | 2009-11-18 | テルモ株式会社 | 人工肺 |
JP4455260B2 (ja) | 2004-10-12 | 2010-04-21 | ヤマハ発動機株式会社 | 部品搬送装置、表面実装機および部品試験装置 |
DE102005031582A1 (de) | 2005-07-06 | 2007-01-11 | Maquet Cardiopulmonary Ag | Vorrichtung zur Behandlung von Blut in einem extrakorporalen Blutkreislauf |
DE102005039446B4 (de) | 2005-08-18 | 2009-06-25 | Ilias-Medical Gmbh | Vorrichtung zur An- und Abreicherung von Stoffen in einer Flüssigkeit |
DE602005022122D1 (de) | 2005-08-22 | 2010-08-12 | St Jude Medical | Werkzeug zur befestigung einer herzstimulatorleitung an einem gewünschten punkt im herz |
US20070107884A1 (en) | 2005-10-27 | 2007-05-17 | Sirkar Kamalesh K | Polymeric hollow fiber heat exchange systems |
JP4500776B2 (ja) | 2006-01-19 | 2010-07-14 | テルモ株式会社 | 人工肺 |
EP2305332B1 (en) | 2006-01-19 | 2018-08-08 | Terumo Kabushiki Kaisha | Oxygenator |
ITMI20060490A1 (it) | 2006-03-17 | 2007-09-18 | Eurosets Srl | Dispositivo integrato per il rioscaldamento e l'ossigenazione del sangue in circuito extracorporeo |
JP4855119B2 (ja) | 2006-03-28 | 2012-01-18 | テルモ株式会社 | フィルタ部材および人工肺 |
JP4714082B2 (ja) | 2006-06-07 | 2011-06-29 | 株式会社東芝 | 屋外装置の発光素子表示構造 |
DE102007010112A1 (de) | 2007-02-28 | 2008-09-04 | Rheinisch-Westfälische Technische Hochschule Aachen | Vorrichtung für den Stoff- und/oder Energieaustausch |
JP5020111B2 (ja) | 2008-02-04 | 2012-09-05 | 株式会社小松製作所 | 油圧制御装置および油圧制御方法、油圧制御装置の調整方法 |
US20100272607A1 (en) | 2009-04-23 | 2010-10-28 | Carpenter Walt L | Radial design oxygenator with heat exchanger and inlet mandrel |
US20100272606A1 (en) | 2009-04-23 | 2010-10-28 | Carpenter Walt L | Radial flow oxygenator/heat exchanger |
US20100269342A1 (en) | 2009-04-23 | 2010-10-28 | Carpenter Walt L | Method of making radial design oxygenator with heat exchanger |
EP2421576B1 (en) | 2009-04-23 | 2017-07-19 | Medtronic Inc. | Radial design oxygenator with heat exchanger |
DK2295646T3 (da) | 2009-08-28 | 2012-07-23 | Bauer Maschinen Gmbh | Boreindretning og borefremgangsmåde |
CN201510571U (zh) | 2009-09-29 | 2010-06-23 | 山东威高新生医疗器械有限公司 | 膜式氧合器 |
JP5418275B2 (ja) | 2010-02-15 | 2014-02-19 | ニプロ株式会社 | 熱交換器および熱交換器一体型人工肺 |
DE102010027973A1 (de) | 2010-04-20 | 2011-10-20 | Ilias-Medical Gmbh | Verfahren und Vorrichtung zur Herstellung eines Membranmodus |
US8388566B2 (en) | 2010-04-29 | 2013-03-05 | Sorin Group Italia, S.r.l. | Oxygenator with integrated arterial filter including filter frame |
US8318092B2 (en) | 2010-04-29 | 2012-11-27 | Sorin Group Italia S.R.L. | Oxygenator with integrated arterial filter |
CN103180032A (zh) * | 2010-05-26 | 2013-06-26 | 查尔斯斯塔克布料实验室公司 | 微制造的人造肺辅助装置及其使用和制造方法 |
EP2612685B1 (en) | 2010-08-19 | 2014-10-08 | Sorin Group Italia S.r.l. | Blood processing unit with modified flow path |
EP2524712B1 (en) | 2011-05-17 | 2018-12-12 | Sorin Group Italia S.r.l. | Blood processing unit with cross blood flow |
BR112013009973A2 (pt) * | 2010-11-15 | 2016-08-02 | Sorin Group Italia Srl | unidade de processamento de sangue com fluxo de sangue circunferencial |
US8518259B2 (en) | 2011-01-27 | 2013-08-27 | Medtronic, Inc. | De-airing oxygenator for treating blood in an extracorporeal blood circuit |
WO2012133372A1 (ja) | 2011-03-31 | 2012-10-04 | テルモ株式会社 | 人工肺 |
US8685319B2 (en) | 2011-04-29 | 2014-04-01 | Medtronic, Inc. | Combination oxygenator and arterial filter device with a fiber bundle of continuously wound hollow fibers for treating blood in an extracorporeal blood circuit |
US8865067B2 (en) | 2011-04-29 | 2014-10-21 | Medtronic, Inc. | Combination oxygenator and arterial filter device for treating blood in an extracorporeal blood circuit |
JP5844585B2 (ja) * | 2011-09-15 | 2016-01-20 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ | 変更された流路を有する血液処理ユニット |
JP6558595B2 (ja) | 2014-01-20 | 2019-08-14 | ユーロセッツ エス.アール.エル. | 患者の血液の体外酸素投与のための装置 |
CN106029118B (zh) | 2014-02-28 | 2018-10-02 | 索林集团意大利有限责任公司 | 用于将集成动脉过滤器设置在氧合器中、使增加的预充量最小化的*** |
-
2014
- 2014-01-09 JP JP2016545788A patent/JP6297706B2/ja not_active Expired - Fee Related
- 2014-01-09 EP EP14723134.4A patent/EP3092015B1/en active Active
- 2014-01-09 US US17/068,190 patent/USRE49759E1/en active Active
- 2014-01-09 CN CN201480072494.2A patent/CN105899245B/zh active Active
- 2014-01-09 WO PCT/IT2014/000005 patent/WO2015104725A1/en active Application Filing
- 2014-01-09 US US15/110,684 patent/US10098994B2/en not_active Ceased
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US10098994B2 (en) | 2018-10-16 |
CN105899245B (zh) | 2018-02-06 |
USRE49759E1 (en) | 2023-12-19 |
EP3092015A1 (en) | 2016-11-16 |
CN105899245A (zh) | 2016-08-24 |
JP2017507686A (ja) | 2017-03-23 |
US20160325036A1 (en) | 2016-11-10 |
EP3092015B1 (en) | 2018-09-19 |
WO2015104725A1 (en) | 2015-07-16 |
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