JP5735211B2 - 簡単な光学系と多重散乱光結像機能とを備えたレーザー走査デジタルカメラ - Google Patents
簡単な光学系と多重散乱光結像機能とを備えたレーザー走査デジタルカメラ Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
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- A61B3/156—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for blocking
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Description
本発明につながる研究は、合衆国国立衛生研究所助成金第EB002346号による連邦政府からの支援を受けている。連邦政府は、本発明にある種の権利を有し得る。
第58−71頁、Hartnett, M.E.及びElsner, A.E.)、“Deep Retinal Vascular Anomal
ous Complexes in Advanced Age-related Macular Degeneration(進行した老化関連黄斑
変性における深網膜血管異常QRS群)”(“Ophthalmology” 第103巻、第12号(
1996年12月)、第2042−2053頁、Hartnett, M.E.ら)に記載されており、
これらは全て本明細書に参考として組み入れられている。本発明者の以前の特許出願に記
載されている装置及び技術は、当該分野における医療補助者又はその他の人のような非専
門家が使用することができる眼の高コントラストなデジタル画像を提供する適度な価格の
持ち運び可能な装置を導入した。しかしながら、更に低価格で、標準的なデジタル画像技
術を使用し、高コントラストな画像を得るために比較的少ない高精度の光学系を含んでいる装置を形成することが当該技術において著しく所望されている。
Claims (12)
- デジタルの網膜結像装置であり、
a.照射源と、
b.当該照射源によって形成された照射経路の一部分を目標物に対して移動させるように作動することができる、前記照射経路内に配置された走査要素と、
c.前記照射源の前記照射経路内に設けられた少なくとも1つのスリットと、
d.ローリングシャッタ機能を有している二次元の相補型の金属酸化物半導体(“CMOS”)検知チップであって、前記CMOS検知チップは、検知経路内に配置されている、前記CMOS検知チップと、を含み、
前記ローリングシャッタ機能を用いて前記検知チップのライン領域を連続的に露呈することによってデジタル像が形成され、前記走査要素は、前記検知経路内には配置されていない、デジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
レンズアレイ及び機械的開口を備えていないことを特徴とするデジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
第一の画像データの組のラインを第二の画像データの組の対応するラインと比較することによって形成された画像の分解能を先鋭化するように作動可能な処理器を更に備えることを特徴とするデジタルの網膜結像装置。 - 請求項3に記載のデジタルの網膜結像装置であり、
前記処理器が更に、前記第一の画像データの組の各ラインと前記第二の画像データの組内の対応するラインとを結合することによって信号対雑音比を向上させるように動作可能であり、前記信号対雑音比は当該結像装置によって結像されるサンプル採取領域を増すことによって得られることを特徴とするデジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
前記CMOS検知チップは、照射源からのビームの整合された光軸に関して1以上の先導ライン又は遅滞ラインを選択するように作動可能であることを特徴とするデジタルの網
膜結像装置。 - 請求項5に記載のデジタルの網膜結像装置であり、
前記網膜結像装置は、多重散乱像を形成するため前記1以上の先導ラインと遅滞ラインとを結合するように作動可能であることを特徴とするデジタルの網膜結像装置。 - 請求項3に記載のデジタルの網膜結像装置であり、
前記網膜結像装置は、共焦点像を形成するため前記1以上の先導ラインと遅滞ラインとを結合するように作動可能であることを特徴とするデジタルの網膜結像装置。 - 請求項3に記載のデジタルの網膜結像装置であり、
前記1以上の先導ラインと遅滞ラインとを結合することによって更に変調された最終的な像の像特性変数を最大化するように動作可能である処理器を更に備え、該像特性変数は、信号対雑音比及び像のコントラストのうち少なくとも1つを含むことを特徴とするデジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
前記照射経路を整形するように作動可能な電子シャッタ又は機械的開口を照射経路内に更に備えていることを特徴とするデジタルの網膜結像装置。 - 請求項9に記載のデジタルの網膜結像装置であり、
前記照射経路が、スリット開口の幅を広くし又は狭くすることによって整形され、それによって、最終的な共焦点像、多重散乱光像又は先鋭化された像のための改良された像特性がもたらされるようになされたことを特徴とするデジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
前記照射源が赤外照射源であることを特徴とするデジタルの網膜結像装置。 - 請求項1に記載のデジタルの網膜結像装置であり、
前記照射経路内で目標物から反射された照射エネルギの波長を検知するように作動可能な前記検知経路内に設けられた第一の検知器アレイと、
立体像、偏光測定及び先導電子シャッタ及び遅滞電子シャッタによる同時の間接的光結像が行われるように、前記第一の検知器アレイに同期するように作動可能な第二の検知器アレイと、
選択された波長のみが前記第二の検知器アレイに到達するように、選択された波長を排除するように作動可能なバリアーフィルタと、を含むことを特徴とするデジタルの網膜結像装置。
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PCT/US2007/012726 WO2007142960A2 (en) | 2006-05-31 | 2007-05-30 | Laser scanning digital camera with simplified optics and potential for multiply scattered light imaging |
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JP2009538697A JP2009538697A (ja) | 2009-11-12 |
JP2009538697A5 JP2009538697A5 (ja) | 2013-11-21 |
JP5735211B2 true JP5735211B2 (ja) | 2015-06-17 |
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US (1) | US7831106B2 (ja) |
EP (1) | EP2030151B1 (ja) |
JP (1) | JP5735211B2 (ja) |
AU (1) | AU2007254999B2 (ja) |
BR (2) | BR122019016664B8 (ja) |
CA (1) | CA2653842C (ja) |
DK (1) | DK2030151T3 (ja) |
ES (1) | ES2459019T3 (ja) |
MX (1) | MX2008015363A (ja) |
WO (1) | WO2007142960A2 (ja) |
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