JP5488594B2 - プリンリボヌクレオシド及びリボヌクレオチドの製造方法 - Google Patents
プリンリボヌクレオシド及びリボヌクレオチドの製造方法 Download PDFInfo
- Publication number
- JP5488594B2 JP5488594B2 JP2011513790A JP2011513790A JP5488594B2 JP 5488594 B2 JP5488594 B2 JP 5488594B2 JP 2011513790 A JP2011513790 A JP 2011513790A JP 2011513790 A JP2011513790 A JP 2011513790A JP 5488594 B2 JP5488594 B2 JP 5488594B2
- Authority
- JP
- Japan
- Prior art keywords
- gene
- strain
- pcr
- seq
- purine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2008138616 | 2008-09-30 | ||
RU2008138616/10A RU2422510C2 (ru) | 2008-09-30 | 2008-09-30 | Способ получения пуриновых рибонуклеозидов и рибонуклеотидов |
PCT/JP2009/067447 WO2010038903A1 (en) | 2008-09-30 | 2009-09-30 | A method for producing purine ribonucleosides and ribonucleotides |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2012503973A JP2012503973A (ja) | 2012-02-16 |
JP2012503973A5 JP2012503973A5 (zh) | 2012-08-02 |
JP5488594B2 true JP5488594B2 (ja) | 2014-05-14 |
Family
ID=41562165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011513790A Expired - Fee Related JP5488594B2 (ja) | 2008-09-30 | 2009-09-30 | プリンリボヌクレオシド及びリボヌクレオチドの製造方法 |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP5488594B2 (zh) |
CN (1) | CN102171346B (zh) |
RU (1) | RU2422510C2 (zh) |
WO (1) | WO2010038903A1 (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103150487B (zh) * | 2012-11-29 | 2016-05-11 | 扬州大学 | 一种构建鸡肌肉肌苷酸合成途径相关关键酶基因网络调控方法 |
WO2014153207A2 (en) * | 2013-03-14 | 2014-09-25 | The Regents Of The University Of California | Recombinant microorganisms having a methanol elongation cycle (mec) |
US9518278B2 (en) | 2013-03-14 | 2016-12-13 | The Regents Of The University Of California | Recombinant microorganisms having a methanol elongation cycle (MEC) |
CN103146786A (zh) * | 2013-03-25 | 2013-06-12 | 天津科技大学 | 一种采用梯度pH顺序控制发酵生产腺苷的方法 |
RU2542387C1 (ru) * | 2013-09-27 | 2015-02-20 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") | БАКТЕРИЯ Bacillus subtilis, ПРОДУЦИРУЮЩАЯ 5`-АМИНОИМИДАЗОЛ-4-КАРБОКСАМИДРИБОЗИД (АИКАР), И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА АИКАР ПУТЕМ КУЛЬТИВИРОВАНИЯ ТАКОЙ БАКТЕРИИ |
CN105670979B (zh) * | 2016-04-26 | 2019-03-26 | 南京工业大学 | 一种核苷磷酸化酶、编码基因及其高产菌株和应用 |
EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
CN112574934B (zh) * | 2020-10-12 | 2022-05-06 | 廊坊梅花生物技术开发有限公司 | 高产鸟苷的工程菌及其构建方法与应用 |
CN112592881B (zh) * | 2021-02-25 | 2021-06-11 | 中国科学院天津工业生物技术研究所 | 用于高效外源蛋白表达和高密度培养的工程枯草芽孢杆菌 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002017351A (ja) * | 2000-07-07 | 2002-01-22 | Ajinomoto Co Inc | ホスホヘキシュロイソメラーゼ及びその遺伝子 |
US7326546B2 (en) * | 2005-03-10 | 2008-02-05 | Ajinomoto Co., Inc. | Purine-derived substance-producing bacterium and a method for producing purine-derived substance |
RU2365622C2 (ru) * | 2006-12-22 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus |
-
2008
- 2008-09-30 RU RU2008138616/10A patent/RU2422510C2/ru active
-
2009
- 2009-09-30 CN CN200980138368.1A patent/CN102171346B/zh active Active
- 2009-09-30 WO PCT/JP2009/067447 patent/WO2010038903A1/en active Application Filing
- 2009-09-30 JP JP2011513790A patent/JP5488594B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
RU2008138616A (ru) | 2010-04-10 |
CN102171346A (zh) | 2011-08-31 |
CN102171346B (zh) | 2014-09-03 |
WO2010038903A1 (en) | 2010-04-08 |
RU2422510C2 (ru) | 2011-06-27 |
JP2012503973A (ja) | 2012-02-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5488594B2 (ja) | プリンリボヌクレオシド及びリボヌクレオチドの製造方法 | |
US7326546B2 (en) | Purine-derived substance-producing bacterium and a method for producing purine-derived substance | |
KR101250826B1 (ko) | 퓨린계 물질 생산균 및 퓨린계 물질의 제조법 | |
CN101432418B (zh) | 能够产生嘌呤物质的细菌和用于产生嘌呤物质的方法 | |
EP2186880A1 (en) | Improved production of riboflavin | |
JP2007530011A (ja) | バチルス属又はエシェリヒア属に属する細菌を使用した発酵によるプリンヌクレオシド及びヌクレオチドの製造方法 | |
JP2001046067A (ja) | 好熱性バチルス属細菌由来のl−リジン生合成系遺伝子 | |
KR100882418B1 (ko) | 이노신을 생산하는 미생물 및 그를 이용한 이노신 제조방법 | |
JP4352716B2 (ja) | バチルス属に属するイノシン生産菌及びイノシンの製造法 | |
JP2003219876A (ja) | プリンヌクレオシドおよびプリンヌクレオチドの製造方法 | |
JP2007075108A6 (ja) | プリンヌクレオシド生産菌及びプリンヌクレオシド製造法 | |
JP2007075108A (ja) | プリンヌクレオシド生産菌及びプリンヌクレオシド製造法 | |
JP5583311B2 (ja) | プリン系物質生産菌及びプリン系物質の製造法 | |
RU2405833C2 (ru) | Способ микробиологического синтеза пуринового нуклеозида 5'-аминоимидазол-4-карбоксамидрибозида (аикар) и штамм бактерий bacillus subtilis - продуцент аикар | |
RU2244004C2 (ru) | Способ получения инозина и 5'-инозиновой кислоты, штамм escherichia coli - продуцент инозина | |
RU2244003C2 (ru) | Способ получения инозина и 5'-инозиновой кислоты, штамм escherichia coli - продуцент инозина | |
RU2403286C2 (ru) | Мутантная фосфорибозилпирофосфатсинтетаза, днк, кодирующая ее, бактерия, содержащая указанную днк, способ продукции пуриновых нуклеозидов и cпособ продукции пуриновых нуклеотидов | |
RU2294962C2 (ru) | БЕЛОК YdhL ИЗ Bacillus amyloliquefaciens, ФРАГМЕНТ ДНК, БАКТЕРИЯ, ПРИНАДЛЕЖАЩАЯ К РОДУ Escherichia ИЛИ Bacillus, - ПРОДУЦЕНТ ПУРИНОВЫХ НУКЛЕОЗИДОВ, СПОСОБ ПОЛУЧЕНИЯ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ | |
KR20220094258A (ko) | 히스티딘에 의한 피드백 억제가 감소된 atp-prt 변이체 및 이를 발현하는 히스티딘 생산 균주 | |
KR20220094261A (ko) | 히스티딘에 의한 피드백 억제가 감소된 atp-prt 변이체 및 이를 발현하는 히스티딘 생산 균주 | |
KR20220094257A (ko) | 히스티딘에 의한 피드백 억제가 감소된 atp-prt 변이체 및 이를 발현하는 히스티딘 생산 균주 | |
KR100859088B1 (ko) | L-쓰레오닌 생산 변이주 및 이를 이용한 l-쓰레오닌생산 방법 | |
KR20220094256A (ko) | 히스티딘에 의한 피드백 억제가 감소된 atp-prt 변이체 및 이를 발현하는 히스티딘 생산 균주 | |
KR20220094260A (ko) | 히스티딘에 의한 피드백 억제가 감소된 atp-prt 변이체 및 이를 발현하는 히스티딘 생산 균주 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120611 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20120611 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140128 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140210 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5488594 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |