JP5336465B2 - 高解像度電気生理学カテーテル - Google Patents
高解像度電気生理学カテーテル Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
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- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
- A61B5/283—Invasive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
- A61B5/283—Invasive
- A61B5/287—Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
- A61B5/6855—Catheters with a distal curved tip
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
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- A61N1/06—Electrodes for high-frequency therapy
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
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- A61B2018/00636—Sensing and controlling the application of energy
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- A61B2018/00636—Sensing and controlling the application of energy
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- A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
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Description
例えば、本発明は以下の項目を提供する。
(項目1)
医療用プローブであって、
遠位端を有する細長部材と、
該細長部材の該遠位端に取り付けられた金属電極と、
該金属電極の内部に埋め込まれ、該金属電極から電気的に絶縁された複数の微小電極と、
該細長部材を通って延在し、該金属電極および該微小電極に接続される少なくとも1つのワイヤと
を備える、医療用プローブ。
(項目2)
上記細長部材は、可撓性である、項目1に記載の医療用プローブ。
(項目3)
上記金属電極は、硬い本体を備える、項目1に記載の医療用プローブ。
(項目4)
上記金属電極は、円筒形である、項目1に記載の医療用プローブ。
(項目5)
上記複数の微小電極は、少なくとも4個の微小電極を備える、項目1に記載の医療用プローブ。
(項目6)
上記微小電極のそれぞれは、4mm以下の直径を有する、項目1に記載の医療用プローブ。
(項目7)
上記微小電極の外面は、上記金属電極の外面に一致し、実質的に連続的な外面を持つ電極集合体を形成する、項目1に記載の医療用プローブ。
(項目8)
上記金属電極は、円筒の壁、該円筒の壁によって取り囲まれた穴、および該穴と連通して上記円筒の壁を貫通する複数の空孔を有し、上記微小電極は、該空孔の内側にそれぞれ配置される、項目1に記載の医療用プローブ。
(項目9)
上記細長部材の上記遠位端は、上記金属電極の上記穴の内側に配置される、項目8に記載の医療用プローブ。
(項目10)
上記空孔の内側にそれぞれ配置される、複数の電気的絶縁性の帯をさらに備え、上記微小電極は、該電気的絶縁性の帯の内側にそれぞれ配置される、項目8に記載の医療用プローブ。
(項目11)
上記穴の内側に配置される、電気的絶縁性の埋め込み用材料をさらに備える、項目8に記載の医療用プローブ。
(項目12)
医療用システムであって、
項目1に記載の上記医療用プローブと、
上記1つのワイヤに結合した高周波(RF)切除供給源と、
上記少なくとも他のワイヤに結合したマッピングプロセッサと
を備える、システム。
(項目13)
医療用の方法であって、
項目1に記載の上記医療用プローブを患者の体内に導入するステップと、
上記金属電極を該患者の体内の組織と接触するように設置するステップと、
上記微小電極のうちの少なくとも1つを介して該組織を感知するステップと、
該組織を切除するように該金属電極から切除エネルギーを伝達するステップと
を含む、方法。
(項目14)
上記組織は、心臓組織である、項目13に記載の方法。
(項目15)
上記医療用プローブは、上記患者の体内に静脈内導入され、上記心臓組織は、心内膜組織である、項目14に記載の方法。
(項目16)
医療用プローブであって、
遠位先端を有する細長部材と、
該細長部材の該遠位先端に取り付けられたキャップ電極と、
該キャップ電極上に配置され、該キャップ電極から電気的に絶縁された複数の微小電極と、
該細長部材を通って延在し、該キャップ電極および該微小電極に接続される少なくとも1つのワイヤと
を備える、プローブ。
(項目17)
上記細長部材は、可撓性である、項目16に記載の医療用プローブ。
(項目18)
上記キャップ電極は、硬い本体を備える、項目16に記載の医療用プローブ。
(項目19)
上記キャップ電極は、金属材料から成る、項目16に記載の医療用プローブ。
(項目20)
上記キャップ電極は、4mm以上の長さを有する、項目16に記載の医療用プローブ。
(項目21)
上記複数の微小電極は、少なくとも4個の微小電極を備える、項目16に記載の医療用プローブ。
(項目22)
上記微小電極のそれぞれは、4mm以下の直径を有する、項目16に記載の医療用プローブ。
(項目23)
上記微小電極の外面は、上記キャップ電極の外面と一致し、実質的に連続的な外面を持つ電極集合体を形成する、項目16に記載の医療用プローブ。
(項目24)
上記微小電極は、上記キャップ電極の中に埋め込まれる、項目16に記載の医療用プローブ。
(項目25)
上記キャップ電極は、円筒の壁と、該円筒の壁によって取り囲まれた穴と、該穴と連通して該円筒の壁を貫通する複数の空孔とを有し、上記微小電極は、該空孔の内側にそれぞれ配置される、項目16に記載の医療用プローブ。
(項目26)
上記細長部材の上記遠位先端は、上記キャップ電極の上記穴の内側に配置される、項目25に記載の医療用プローブ。
(項目27)
上記空孔の内側にそれぞれ配置される、複数の電気的絶縁性の帯をさらに備え、上記微小電極は、該電気的絶縁性の帯の内側にそれぞれ配置される、項目25に記載の医療用プローブ。
(項目28)
上記穴の内側に配置される電気的絶縁性の埋め込み用材料をさらに備える、項目25に記載の医療用プローブ。
(項目29)
上記キャップ電極に対し近位の上記細長部材の周囲に取り付けられた少なくとも1つのリング電極をさらに備え、上記少なくとも1つのワイヤは、該少なくとも1つのリング電極に接続される、項目16に記載の医療用プローブ。
(項目30)
医療用システムであって、
項目16の医療用プローブと、
上記1つのワイヤに結合した高周波(RF)切除供給源と、
上記少なくとも他のワイヤに結合したマッピングプロセッサと
を備える、システム。
(項目31)
医療用の方法であって、
項目15に記載の上記医療用プローブを患者の体内に導入するステップと、
上記キャップ電極を該患者の体内の組織と接触するように設置するステップと、
上記微小電極のうちの少なくとも1つを介して該組織を感知するステップと、
該組織を切除するために該金属電極から切除エネルギーを伝達するステップと
を含む、方法。
(項目32)
上記組織は、心臓組織である、項目31に記載の方法。
(項目33)
上記医療用プローブは、上記患者の体内に静脈内導入され、上記心臓組織は、心内膜組織である、項目32に記載の方法。
(項目34)
医療用プローブであって、
遠位端を有する細長部材と、
該細長部材の該遠位端に取り付けられた硬い電極と、
該硬い電極上に配置され、該硬い電極から電気的に絶縁された複数の微小電極と、
該細長部材を通って延在し、該硬い電極および該微小電極に接続される少なくとも1つのワイヤと
を備える、プローブ。
(項目35)
上記細長部材は、可撓性である、項目34に記載の医療用プローブ。
(項目36)
上記硬い電極は、金属材料から成る、項目34に記載の医療用プローブ。
(項目37)
上記硬い電極は、円筒形である、項目34に記載の医療用プローブ。
(項目38)
上記複数の微小電極は、少なくとも4個の微小電極を備える、項目34に記載の医療用プローブ。
(項目39)
上記微小電極のそれぞれは、4mm以下の直径を有する、項目34に記載の医療用プローブ。
(項目40)
上記微小電極の外面は、上記硬い電極の外面と一致し、実質的に連続的な外面を持つ電極集合体を形成する、項目34に記載の医療用プローブ。
(項目41)
上記微小電極は、上記硬い電極の中に埋め込まれる、項目34に記載の医療用プローブ。
(項目42)
上記硬い電極は、円筒の壁と、該円筒の壁によって取り囲まれた穴と、該穴と連通して該円筒の壁を貫通する複数の空孔とを有し、上記微小電極は、該空孔の内側にそれぞれ配置される、項目34に記載の医療用プローブ。
(項目43)
上記細長部材の上記遠位端は、上記硬い電極の上記穴の内側に配置される、項目42に記載の医療用プローブ。
(項目44)
上記空孔の内側にそれぞれ配置される、複数の電気的絶縁性の帯をさらに備え、上記微小電極は、該電気的絶縁性の帯の内側にそれぞれ配置される、項目42に記載の医療用プローブ。
(項目45)
上記穴の内側に配置される電気的絶縁性の埋め込み用材料をさらに備える、項目42に記載の医療用プローブ。
(項目46)
医療用システムであって、
項目34に記載の上記医療用プローブと、
上記1つのワイヤに結合した高周波(RF)切除供給源と、
上記少なくとも他のワイヤに結合したマッピングプロセッサと
を備える、システム。
(項目47)
医療用の方法であって、
項目34に記載の上記医療用プローブを患者の体内に導入するステップと、
上記硬い電極を該患者の体内の組織と接触するように設置するステップと、
上記微小電極のうちの少なくとも1つを介して該組織を感知するステップと、
該組織を切除するように該硬い電極から切除エネルギーを伝達するステップと、
を含む、方法。
(項目48)
上記組織は、心臓組織である、項目47に記載の方法。
(項目49)
上記医療用プローブは、上記患者の体内に静脈内導入され、上記心臓組織は、心内膜組織である、項目48に記載の方法。
(項目50)
医療用プローブの製造方法であって、
壁および該壁によって取り囲まれた穴を有する、円筒形の電極を提供するステップと、
該壁を通して該穴に通じる複数の空孔を形成するステップと、
該空孔の中に複数の微小電極をそれぞれ取り付けるステップと、
細長部材の遠位端を該穴の中に取り付けるステップと、
少なくとも1つのワイヤを該電極および該微小電極に接続するステップと、
該細長部材を通して該少なくとも1つのワイヤを配置するステップと
を含む、方法。
(項目51)
上記電極は、半球形の遠位先端を有し、上記細長部材の遠位先端は、上記穴の中に取り付けられる、項目50に記載の方法。
(項目52)
上記空孔は、上記壁を通してドリルで穿孔され、上記穴に通じる、項目50に記載の方法。
(項目53)
上記細長部材は、可撓性である、項目50に記載の方法。
(項目54)
上記複数の微小電極は、少なくとも4個の微小電極を備える、項目50に記載の方法。
(項目55)
複数の電気的絶縁性の帯をそれぞれ上記空孔の中に取り付けるステップをさらに含み、上記微小電極はそれぞれ、該電気的絶縁性の帯の内側に取り付けられる、項目50に記載の方法。
(項目56)
上記細長部材の上記遠位端を上記穴の内側に取り付ける前に、電気的絶縁性の埋め込み用材料を該穴の中に導入するステップをさらに含む、項目50に記載の方法。
(項目57)
上記微小電極のそれぞれは、4mm以下の直径を有する、項目50に記載の方法。
(項目58)
実質的に連続的な外面を持つ電極集合体を形成するように、上記電極の外面および上記微小電極の外面を研磨するステップをさらに含む、項目50に記載の方法。
Claims (15)
- 医療用プローブであって、
遠位端を有する細長部材と、
該細長部材の該遠位端に取り付けられた金属電極と、
該金属電極の内部に埋め込まれ、該金属電極から電気的に絶縁された複数の微小電極と、
該金属電極上、該金属電極の下、または、該金属電極内の温度センサと、
該細長部材を通って延在し、該金属電極および該微小電極に接続される少なくとも1つのワイヤと
を備える、医療用プローブ。 - 前記金属電極は、硬い本体を備える、請求項1に記載の医療用プローブ。
- 前記金属電極は、円筒形である、請求項1または2に記載の医療用プローブ。
- 前記微小電極のそれぞれは、4mm以下の直径を有する、請求項1〜3のいずれかに記載の医療用プローブ。
- 前記微小電極の外面は、前記金属電極の外面に一致し、実質的に連続的な外面を持つ電極集合体を形成する、請求項1〜4のいずれかに記載の医療用プローブ。
- 前記金属電極は、円筒の壁と、該円筒の壁によって取り囲まれた穴と、該穴と連通して該円筒の壁を通って延びる複数の空孔とを有し、前記微小電極は、該空孔の内側にそれぞれ配置される、請求項1〜5のいずれかに記載の医療用プローブ。
- 前記細長部材の前記遠位端は、前記金属電極の前記穴の内側に配置される、請求項6に記載の医療用プローブ。
- 前記空孔の内側にそれぞれ配置される、複数の電気的絶縁性の帯をさらに備え、前記微小電極は、該電気的絶縁性の帯の内側にそれぞれ配置される、請求項6に記載の医療用プローブ。
- 前記金属電極は、キャップ電極である、請求項1〜8のいずれかに記載の医療用プローブ。
- 医療用プローブの製造方法であって、
壁と、該壁によって取り囲まれた穴とを有する、円筒形の電極を提供することと、
該壁を通して該穴に通じる複数の空孔を形成することと、
該空孔の中に複数の微小電極をそれぞれ取り付けることと、
該円筒形の電極上、該円筒形の電極の下、または、該円筒形の電極内に温度センサを取り付けることと、
細長部材の遠位端を該穴の中に取り付けることと、
少なくとも1つのワイヤを該電極および該微小電極に接続することと、
該細長部材を通して該少なくとも1つのワイヤを配置することと
を含む、方法。 - 前記円筒形の電極は、半球形の遠位先端を有し、前記細長部材の遠位先端は、前記穴の中に取り付けられる、請求項10に記載の方法。
- 前記空孔は、前記壁を通してドリルで穿孔され、前記穴に通じる、請求項10または11に記載の方法。
- 複数の電気的絶縁性の帯をそれぞれ前記空孔の中に取り付けることをさらに含み、前記微小電極はそれぞれ、該電気的絶縁性の帯の内側に取り付けられる、請求項10〜12のいずれかに記載の方法。
- 前記微小電極のそれぞれは、4mm以下の直径を有する、請求項10〜13のいずれかに記載の方法。
- 実質的に連続的な外面を持つ電極集合体を形成するように、前記円筒形の電極の外面および前記微小電極の外面を研磨することをさらに含む、請求項10〜14のいずれかに記載の方法。
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2008
- 2008-03-26 EP EP15174537.9A patent/EP3000390A1/en not_active Withdrawn
- 2008-03-26 EP EP08744409.7A patent/EP2136702B1/en not_active Not-in-force
- 2008-03-26 KR KR20097020044A patent/KR101490374B1/ko not_active IP Right Cessation
- 2008-03-26 US US12/056,210 patent/US20080243214A1/en not_active Abandoned
- 2008-03-26 WO PCT/US2008/058324 patent/WO2008118992A1/en active Application Filing
- 2008-03-26 CA CA002682055A patent/CA2682055A1/en not_active Abandoned
- 2008-03-26 JP JP2010501202A patent/JP5336465B2/ja not_active Expired - Fee Related
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2013
- 2013-08-01 JP JP2013160581A patent/JP2014012174A/ja active Pending
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2015
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US11589768B2 (en) | 2014-10-13 | 2023-02-28 | Boston Scientific Scimed Inc. | Tissue diagnosis and treatment using mini-electrodes |
US10603105B2 (en) | 2014-10-24 | 2020-03-31 | Boston Scientific Scimed Inc | Medical devices with a flexible electrode assembly coupled to an ablation tip |
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Also Published As
Publication number | Publication date |
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EP2136702B1 (en) | 2015-07-01 |
US20150133914A1 (en) | 2015-05-14 |
KR101490374B1 (ko) | 2015-02-05 |
CA2682055A1 (en) | 2008-10-02 |
JP2014012174A (ja) | 2014-01-23 |
WO2008118992A1 (en) | 2008-10-02 |
EP3000390A1 (en) | 2016-03-30 |
JP2010522623A (ja) | 2010-07-08 |
KR20100021401A (ko) | 2010-02-24 |
US20080243214A1 (en) | 2008-10-02 |
EP2136702A1 (en) | 2009-12-30 |
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