JP5155326B2 - 回分量制御デバイス - Google Patents
回分量制御デバイス Download PDFInfo
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- JP5155326B2 JP5155326B2 JP2009533434A JP2009533434A JP5155326B2 JP 5155326 B2 JP5155326 B2 JP 5155326B2 JP 2009533434 A JP2009533434 A JP 2009533434A JP 2009533434 A JP2009533434 A JP 2009533434A JP 5155326 B2 JP5155326 B2 JP 5155326B2
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- 238000001802 infusion Methods 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 15
- 238000002347 injection Methods 0.000 claims description 14
- 239000007924 injection Substances 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 11
- 230000001954 sterilising effect Effects 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 208000030533 eye disease Diseases 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 description 35
- 229940079593 drug Drugs 0.000 description 32
- 238000012377 drug delivery Methods 0.000 description 20
- 210000005252 bulbus oculi Anatomy 0.000 description 16
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- 208000005590 Choroidal Neovascularization Diseases 0.000 description 2
- 206010060823 Choroidal neovascularisation Diseases 0.000 description 2
- 241000701022 Cytomegalovirus Species 0.000 description 2
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- 239000005441 aurora Substances 0.000 description 2
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- 208000002780 macular degeneration Diseases 0.000 description 2
- 210000001525 retina Anatomy 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 206010012689 Diabetic retinopathy Diseases 0.000 description 1
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- 206010061218 Inflammation Diseases 0.000 description 1
- 208000001344 Macular Edema Diseases 0.000 description 1
- 206010025415 Macular oedema Diseases 0.000 description 1
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- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003732 agents acting on the eye Substances 0.000 description 1
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- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
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- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/14224—Diaphragm type
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
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- A—HUMAN NECESSITIES
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
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- A61M2210/0612—Eyes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/01—Motorized syringe
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Description
本発明は、薬剤を眼球内へと注入するデバイスに関し、より詳細には、回分量制御機構を備えた眼薬供与デバイスに関する。
Claims (17)
- 内側面と外側面とを有する供与チャンバであって、上記内側面は所定量の物質を受容するキャビティを画成する供与チャンバと、
上記供与チャンバの上記内側面と係合されたプランジャであって、該プランジャは上記供与チャンバの上記キャビティ内を摺動し得、該プランジャは上記供与チャンバの上記内側面に対して流体的にシールされるプランジャと、
当該注入デバイスの動作を制御するコントローラと、
上記物質が上記供与チャンバから供与された後で飛ばされることにより当該デバイスを作動不能とするヒューズと、
殺菌操作に耐えるメモリ・デバイスであって、複数の対のヒューズ及び抵抗器を備え、各ヒューズと抵抗器とが直列に接続され、前記複数の対のヒューズ及び抵抗器は並列に接続される、メモリ・デバイスと、
上記供与チャンバおよび上記プランジャを少なくとも部分的に取り囲むハウジングとを備え、
上記コントローラは上記メモリ・デバイスから回分量データを読み取り且つ当該注入デバイスを操作することで上記回分量データに対応する回分量を供与する、
注入デバイス。 - 前記供与チャンバに対して流体的に連結された針を更に備えて成る、請求項1記載の注入デバイス。
- 前記供与チャンバに熱接触して前記物質を加熱するヒータを更に備えて成る、請求項1記載の注入デバイス。
- 前記プランジャの移動を制限するプランジャ停止機構を更に備えて成る、請求項1記載の注入デバイス。
- 前記物質は眼球の疾患を治療する薬剤である、請求項1記載の注入デバイス。
- 当該デバイスを作動不能とする前記ヒューズと直列なライトを更に備えて成る、請求項1記載の注入デバイス。
- 当該注入デバイスに対して電力を提供する電源を更に備えて成る、請求項1記載の注入デバイス。
- 前記電源はバッテリである、請求項7記載の注入デバイス。
- 前記プランジャを駆動するアクチュエータを更に備えて成る、請求項1記載の注入デバイス。
- 先端セグメントと再使用制限アセンブリとを備えた眼科用注入システムであって、
上記先端セグメントは、
内側面と外側面とを有する供与チャンバであって、上記内側面は所定量の物質を受容するキャビティを画成する供与チャンバと、
上記供与チャンバの上記内側面と係合されたプランジャであって、該プランジャは上記供与チャンバの上記キャビティ内を摺動し得、該プランジャは上記供与チャンバの上記内側面に対して流体的にシールされ、該プランジャは基端および末端を有し、該基端は第1の機械的リンク機構インタフェースを有するプランジャと、
上記物質が上記供与チャンバから供与された後で飛ばされることにより当該システムを作動不能とするヒューズと、
殺菌操作に耐えるメモリ・デバイスであって、複数の対のヒューズ及び抵抗器を備え、各ヒューズと抵抗器とが直列に接続され、前記複数の対のヒューズ及び抵抗器は並列に接続される、メモリ・デバイスと、
上記供与チャンバおよび上記プランジャを少なくとも部分的に取り囲む第1ハウジングとを備え、
上記再使用制限アセンブリは、
電源と、
当該システムの動作を制御するコントローラと、
シャフトを有するアクチュエータと、
上記シャフトの端部上に配置された第2の機械的リンク機構インタフェースと、
上記コントローラおよび上記アクチュエータを少なくとも部分的に取り囲む第2ハウジングとを備え、
上記コントローラは上記メモリ・デバイスから回分量データを読み取り且つ当該注入デバイスを操作することで上記回分量データに対応する回分量を供与する、
眼科用注入システム。 - 前記メモリ・デバイスを前記コントローラに対して連結するインタフェースを更に備えて成る、請求項10記載のシステム。
- 前記コントローラは、前記シャフトが算出された距離だけ移動されることにより、前記プランジャを変位させ、且つ、前記回分量データに対応する量の前記物質を前記供与チャンバから出射させる如く、前記アクチュエータを操作する、請求項10記載のシステム。
- 前記供与チャンバに対して流体的に連結された針を更に備えて成る、請求項10記載のシステム。
- 前記供与チャンバに熱接触して前記物質を加熱するヒータを更に備えて成る、請求項10記載のシステム。
- 前記物質は眼球の疾患を治療する薬剤である、請求項10記載のシステム。
- 前記先端セグメントは、当該システムを作動不能とする前記ヒューズと直列なライトを更に備えて成る、請求項10記載のシステム。
- 前記電源はバッテリである、請求項10記載のシステム。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92149706P | 2006-10-16 | 2006-10-16 | |
US60/921,497 | 2006-10-16 | ||
US11/688,573 US7811252B2 (en) | 2006-05-17 | 2007-03-20 | Dosage control device |
US11/688,573 | 2007-03-20 | ||
PCT/US2007/080376 WO2008112011A2 (en) | 2006-10-16 | 2007-10-04 | Dosage control device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010506675A JP2010506675A (ja) | 2010-03-04 |
JP5155326B2 true JP5155326B2 (ja) | 2013-03-06 |
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ID=39721776
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009533434A Expired - Fee Related JP5155326B2 (ja) | 2006-10-16 | 2007-10-04 | 回分量制御デバイス |
JP2009533442A Expired - Fee Related JP5260532B2 (ja) | 2006-10-16 | 2007-10-09 | 使い捨て電池駆動眼科用ハンドピース |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009533442A Expired - Fee Related JP5260532B2 (ja) | 2006-10-16 | 2007-10-09 | 使い捨て電池駆動眼科用ハンドピース |
Country Status (14)
Country | Link |
---|---|
US (2) | US7811252B2 (ja) |
EP (2) | EP2077809A2 (ja) |
JP (2) | JP5155326B2 (ja) |
KR (1) | KR20090091133A (ja) |
CN (3) | CN101534758A (ja) |
AR (9) | AR063290A1 (ja) |
AU (2) | AU2007348948A1 (ja) |
BR (1) | BRPI0717303B8 (ja) |
CA (2) | CA2664635A1 (ja) |
ES (1) | ES2614646T3 (ja) |
MX (1) | MX2009003395A (ja) |
RU (1) | RU2009118434A (ja) |
TW (2) | TW200826986A (ja) |
WO (2) | WO2008112011A2 (ja) |
Families Citing this family (50)
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US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
DE10224750A1 (de) | 2002-06-04 | 2003-12-24 | Fresenius Medical Care De Gmbh | Vorrichtung zur Behandlung einer medizinischen Flüssigkeit |
US8197231B2 (en) | 2005-07-13 | 2012-06-12 | Purity Solutions Llc | Diaphragm pump and related methods |
US20080114423A1 (en) | 2006-05-15 | 2008-05-15 | Grenon Stephen M | Apparatus for inner eyelid treatment of meibomian gland dysfunction |
US7981145B2 (en) | 2005-07-18 | 2011-07-19 | Tearscience Inc. | Treatment of meibomian glands |
US20070060988A1 (en) | 2005-07-18 | 2007-03-15 | Grenon Stephen M | Melting meibomian gland obstructions |
US20070016256A1 (en) | 2005-07-18 | 2007-01-18 | Korb Donald R | Method and apparatus for treating gland dysfunction |
WO2013003594A2 (en) | 2011-06-28 | 2013-01-03 | Tearscience, Inc. | Methods and systems for treating meibomian gland dysfunction using radio-frequency energy |
US20090043365A1 (en) | 2005-07-18 | 2009-02-12 | Kolis Scientific, Inc. | Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma |
US7981095B2 (en) | 2005-07-18 | 2011-07-19 | Tearscience, Inc. | Methods for treating meibomian gland dysfunction employing fluid jet |
US8950405B2 (en) * | 2006-05-15 | 2015-02-10 | Tearscience, Inc. | Treatment of obstructive disorders of the eye or eyelid |
US8128674B2 (en) | 2006-05-15 | 2012-03-06 | Tearscience, Inc. | System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction |
US9314369B2 (en) * | 2006-05-15 | 2016-04-19 | Tearscience, Inc. | System for inner eyelid treatment of meibomian gland dysfunction |
US8137390B2 (en) | 2006-05-15 | 2012-03-20 | Tearscience, Inc. | System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction |
US8128673B2 (en) | 2006-05-15 | 2012-03-06 | Tearscience, Inc. | System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction |
US20080281292A1 (en) * | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
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- 2007-10-09 MX MX2009003395A patent/MX2009003395A/es not_active Application Discontinuation
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