JP5087167B2 - ビフィズス菌大腸デリバリーカプセル及びその製造方法 - Google Patents

ビフィズス菌大腸デリバリーカプセル及びその製造方法 Download PDF

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Publication number
JP5087167B2
JP5087167B2 JP2011250418A JP2011250418A JP5087167B2 JP 5087167 B2 JP5087167 B2 JP 5087167B2 JP 2011250418 A JP2011250418 A JP 2011250418A JP 2011250418 A JP2011250418 A JP 2011250418A JP 5087167 B2 JP5087167 B2 JP 5087167B2
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JP
Japan
Prior art keywords
capsule
chitosan
mass
bifidobacteria
containing layer
Prior art date
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Active
Application number
JP2011250418A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012149032A (ja
Inventor
奈津子 今村
邦昭 山中
峯村　　剛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Pharma Inc
Freund Corp
Original Assignee
Nisshin Pharma Inc
Freund Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Pharma Inc, Freund Corp filed Critical Nisshin Pharma Inc
Priority to JP2011250418A priority Critical patent/JP5087167B2/ja
Priority to PCT/JP2011/076952 priority patent/WO2012090623A1/ja
Priority to KR1020137018429A priority patent/KR20130133809A/ko
Priority to CN2011800630072A priority patent/CN103327990A/zh
Priority to TW100143797A priority patent/TWI543780B/zh
Publication of JP2012149032A publication Critical patent/JP2012149032A/ja
Application granted granted Critical
Publication of JP5087167B2 publication Critical patent/JP5087167B2/ja
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2011250418A 2010-12-28 2011-11-16 ビフィズス菌大腸デリバリーカプセル及びその製造方法 Active JP5087167B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2011250418A JP5087167B2 (ja) 2010-12-28 2011-11-16 ビフィズス菌大腸デリバリーカプセル及びその製造方法
PCT/JP2011/076952 WO2012090623A1 (ja) 2010-12-28 2011-11-22 ビフィズス菌大腸デリバリーカプセル及びその製造方法
KR1020137018429A KR20130133809A (ko) 2010-12-28 2011-11-22 비피더스균 대장 딜리버리 캡슐 및 그 제조 방법
CN2011800630072A CN103327990A (zh) 2010-12-28 2011-11-22 双歧杆菌大肠递送胶囊及其制造方法
TW100143797A TWI543780B (zh) 2010-12-28 2011-11-29 雙叉乳酸桿菌大腸遞送膠囊及其製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010293842 2010-12-28
JP2010293842 2010-12-28
JP2011250418A JP5087167B2 (ja) 2010-12-28 2011-11-16 ビフィズス菌大腸デリバリーカプセル及びその製造方法

Publications (2)

Publication Number Publication Date
JP2012149032A JP2012149032A (ja) 2012-08-09
JP5087167B2 true JP5087167B2 (ja) 2012-11-28

Family

ID=46382743

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011250418A Active JP5087167B2 (ja) 2010-12-28 2011-11-16 ビフィズス菌大腸デリバリーカプセル及びその製造方法

Country Status (5)

Country Link
JP (1) JP5087167B2 (zh)
KR (1) KR20130133809A (zh)
CN (1) CN103327990A (zh)
TW (1) TWI543780B (zh)
WO (1) WO2012090623A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5102401B1 (ja) * 2012-03-30 2012-12-19 森下仁丹株式会社 大腸特異崩壊性カプセル
JP5496432B1 (ja) * 2012-12-21 2014-05-21 日清ファルマ株式会社 大腸送達カプセル及びその製造方法
KR20150100682A (ko) * 2012-12-21 2015-09-02 닛신 파마 가부시키가이샤 대장 송달 캡슐 및 그 제조방법
JP6243276B2 (ja) * 2014-03-31 2017-12-06 株式会社ファンケル 原薬の耐酸性を向上させたハードカプセル製剤
JP6457963B2 (ja) * 2016-02-25 2019-01-23 日清ファルマ株式会社 大腸デリバリーカプセル製剤
CN108066296B (zh) * 2016-11-11 2020-11-17 南京益恒寿生命科技有限公司 一种生物学活性组分结肠靶向组合物及其应用
CN109464425B (zh) * 2018-12-29 2021-02-05 上海交大昂立股份有限公司 一种益生菌包埋颗粒及其制备方法
JP6578459B1 (ja) * 2019-02-28 2019-09-18 アピ株式会社 ハードカプセル及びその製造方法
JP2021014422A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 便性改善剤
JP2021014421A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 Ｑｏｌ改善剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0669476B2 (ja) * 1986-11-07 1994-09-07 新次郎 辻 ゼラチン硬カプセルのフイルムコ−テイング方法
EP1203590B1 (en) * 1999-08-09 2007-07-04 Dainippon Sumitomo Pharma Co., Ltd. Solid preparations containing chitosan powder and process for producing the same
JP2003012526A (ja) * 2001-06-27 2003-01-15 Sunstar Inc 有用生菌内包製剤
JP5386176B2 (ja) * 2006-12-21 2014-01-15 フロイント産業株式会社 キトサン溶液及び該溶液から形成されたキトサンコーティング製剤
JP5487379B2 (ja) * 2008-03-19 2014-05-07 森下仁丹株式会社 血中リン濃度上昇抑制剤

Also Published As

Publication number Publication date
CN103327990A (zh) 2013-09-25
TW201249481A (en) 2012-12-16
WO2012090623A1 (ja) 2012-07-05
TWI543780B (zh) 2016-08-01
KR20130133809A (ko) 2013-12-09
JP2012149032A (ja) 2012-08-09

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