JP5009898B2 - 心臓弁及びその製造方法 - Google Patents
心臓弁及びその製造方法 Download PDFInfo
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- JP5009898B2 JP5009898B2 JP2008506777A JP2008506777A JP5009898B2 JP 5009898 B2 JP5009898 B2 JP 5009898B2 JP 2008506777 A JP2008506777 A JP 2008506777A JP 2008506777 A JP2008506777 A JP 2008506777A JP 5009898 B2 JP5009898 B2 JP 5009898B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/243—Deployment by mechanical expansion
- A61F2/2433—Deployment by mechanical expansion using balloon catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2439—Expansion controlled by filaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/005—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0058—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
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- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Prostheses (AREA)
- External Artificial Organs (AREA)
Description
Claims (12)
- 第一のアンカーフレームを通る開口を形成する表面を有し、共通軸を中心としてリング状に形成されている第一のアンカーフレームと、
前記第一のアンカーフレームと結合した二つ以上の小葉であって、心臓弁の開口を通る液体の一方向の流れのために開いた状態と閉じた状態の間を反復して動く二つ以上の小葉と、
前記心臓弁が完全に展開した形態で前記第一のアンカーフレームを通る開口を形成する前記表面上で上下に延びるアンカー部材と、該アンカー部材は、それぞれがかえしを有する第一の端及び第二の端を有することと、
該アンカー部材の第一の端及び第二の端の間に位置され、該アンカー部材の該第一の端及び該第二の端を同第一の端及び第二の端が相互に離間するように拘束する展開部材とを備え、同展開部材を該アンカー部材の該第一の端及び該第二の端から引っ込めることにより、拘束が取り払われ、該アンカー部材の該第一の端と該第二の端のうち少なくともいずれか一方は、相互に対して移動することを特徴とする、心臓弁。 - 前記心臓弁を予め定められた場所にアンカー固定した後に前記開口の外側での液体の漏れを防ぐために前記第一のアンカーフレームに封止物質を含むことを特徴とする、請求項1に記載の心臓弁。
- 前記第一のアンカーフレームと前記展開部材との間に配置された封止物質を含み、前記展開部材を除去して前記心臓弁を前記予め定められた場所にアンカー固定し、前記封止物質が前記心臓弁の開口の外側での液体の漏れを防止することを特徴とする、請求項2に記載の心臓弁。
- 第二のアンカーフレームであって、前記第二のアンカーフレームを通る開口を形成する表面を有する第二のアンカーフレームと、
前記第一のアンカーフレームと第二のアンカーフレームとの間で延びる支柱であって、前記二つ以上の小葉が前記第一のアンカーフレーム及び前記支柱に結合される支柱と、
前記第二のアンカーフレームの表面から延びる二つ以上のアンカー部材とを含むことを特徴とする、請求項1から3のいずれか一項に記載の心臓弁。 - 基端と先端とを含む送達カテーテルを更に含み、前記心臓弁が前記送達カテーテルの前記基端と前記先端との間に配置されることを特徴とする、請求項1から4のいずれか一項に記載の心臓弁。
- 前記送達カテーテルは、前記送達カテーテルの前記基端から前記先端の方へ延びる第一の送達管腔、第二の送達管腔、及び第三の送達管腔と、
第一の配置ガイド、第二の配置ガイド、及び第三の配置ガイドであって、その各々は管腔を有する細長体を含み、各々が前記第一の送達管腔、前記第二の送達管腔、及び前記第三の送達管腔内の長手方向にそれぞれ移動して前記第一、前記第二、及び前記第三の配置ガイドの一部が前記送達カテーテルの前記先端を超えて延びることができるように配置される、第一、第二、第三の配置ガイドとを含み、
前記展開部材の別々の部分は、前記第一、前記第二、及び前記第三の配置ガイドの管腔を通って延びて前記アンカー部材の前記第一の端と前記第二の端を拘束された状態に保持し、前記展開部材の前記別々の部分を前記管腔を通して引っ込めて前記心臓弁を前記第一、前記第二、及び前記第三の配置ガイド及び前記送達カテーテルから解放することができることを特徴とする、請求項5に記載の心臓弁。 - 前記第一、前記第二、及び前記第三の配置ガイドが前記送達カテーテルの先端を超えて延びると、前記第一のアンカーフレームが拘束された形態から完全に展開した形態に広がることを特徴とする、請求項6に記載の心臓弁。
- 前記送達カテーテルが前記先端に隣接して配置された第一の膨張可能なバルーンと、前記カテーテルの細長体の中で前記第一の膨張可能なバルーンから前記先端まで長手方向に延びる第一の膨張管腔とを含み、前記第一の膨張可能なバルーンは少なくとも部分的に前記第一のアンカーフレームの前記開口内に配置され、前記第一の膨張可能なバルーンが膨張して心臓弁を完全に展開した形態に広げることを特徴とする、請求項6または7に記載の心臓弁。
- 第二のアンカーフレームであって、前記第二のアンカーフレームを通る開口を形成する表面を有する第二のアンカーフレームと、
前記第一のアンカーフレームと前記第二のアンカーフレームとの間に延びる支柱であって、前記二つ以上の小葉が前記第一のアンカーフレームと前記支柱に結合される支柱と、
前記第二のアンカーフレームの前記表面から延びる二つ以上のアンカー部材とを含み、
前記送達カテーテルが前記先端に隣接して配置された第二の膨張可能なバルーンと、前記カテーテルの細長体の中で前記第二の膨張可能なバルーンから前記先端まで長手方向に延びる第二の膨張管腔とを含み、前記第二の膨張可能なバルーンは、前記第一の膨張可能なバルーンから離れて少なくとも部分的に前記第二のアンカーフレームの前記開口内に配置され、前記第二の膨張可能なバルーンが膨張して前記心臓弁を完全に展開した形態に広げることを特徴とする、請求項8に記載の心臓弁。 - 心臓弁の第一のアンカーフレームであって、前記第一のアンカーフレームを通る開口を形成する表面を有し、共通軸を中心としてリング状に形成されている第一のアンカーフレームを形成する工程と、
前記第一のアンカーフレーム上に、アンカー部材であって前記心臓弁の完全に展開した形態で前記第一のアンカーフレームを通る開口を形成する表面上で上下に延びるアンカー部材を形成する工程と、
一対のアンカー部材の間を通過する展開部材により該アンカー部材を張力の下で第1の予め定められた形に拘束し、展開部材を一対のアンカー部材の間から除去すると、アンカー部材は第2の予め定められた形に移動する工程と、
二つ以上の小葉を前記第一のアンカーフレームに結合する工程とを含むことを特徴とする、心臓弁の製造方法。 - 第一の膨張可能なバルーンを少なくとも部分的に前記第一のアンカーフレームを通る開口内に配置する工程を含むことを特徴とする、請求項10に記載の心臓弁の製造方法。
- 前記心臓弁の第二のアンカーフレームであって、前記第二のアンカーフレームを通る開口を形成する表面を有する第二のアンカーフレームを形成する工程と、
前記第二のアンカーフレーム上に二つ以上のアンカー部材を形成する工程と、
前記第一のアンカーフレーム及び前記第二のアンカーフレームを支柱で結合する工程と、
前記二つ以上の小葉を前記第一のアンカーフレーム及び前記支柱に結合する工程とを含むことを特徴とする、請求項10または11に記載の心臓弁の製造方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/107,162 US7722666B2 (en) | 2005-04-15 | 2005-04-15 | Valve apparatus, system and method |
US11/107,162 | 2005-04-15 | ||
PCT/US2006/014192 WO2006113496A2 (en) | 2005-04-15 | 2006-04-17 | Valve apparatus, system and method |
Publications (3)
Publication Number | Publication Date |
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JP2008536581A JP2008536581A (ja) | 2008-09-11 |
JP2008536581A5 JP2008536581A5 (ja) | 2009-03-19 |
JP5009898B2 true JP5009898B2 (ja) | 2012-08-22 |
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Application Number | Title | Priority Date | Filing Date |
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JP2008506777A Expired - Fee Related JP5009898B2 (ja) | 2005-04-15 | 2006-04-17 | 心臓弁及びその製造方法 |
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Country | Link |
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US (3) | US7722666B2 (ja) |
EP (1) | EP1887979B1 (ja) |
JP (1) | JP5009898B2 (ja) |
CA (1) | CA2604941C (ja) |
WO (1) | WO2006113496A2 (ja) |
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2005
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2006
- 2006-04-17 CA CA2604941A patent/CA2604941C/en not_active Expired - Fee Related
- 2006-04-17 EP EP06750271.6A patent/EP1887979B1/en not_active Not-in-force
- 2006-04-17 WO PCT/US2006/014192 patent/WO2006113496A2/en active Application Filing
- 2006-04-17 JP JP2008506777A patent/JP5009898B2/ja not_active Expired - Fee Related
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US20100100173A1 (en) | 2010-04-22 |
US20060235509A1 (en) | 2006-10-19 |
CA2604941A1 (en) | 2006-10-26 |
WO2006113496A3 (en) | 2007-01-04 |
EP1887979A2 (en) | 2008-02-20 |
WO2006113496A2 (en) | 2006-10-26 |
JP2008536581A (ja) | 2008-09-11 |
CA2604941C (en) | 2014-03-25 |
US7722666B2 (en) | 2010-05-25 |
EP1887979B1 (en) | 2015-08-05 |
US8512399B2 (en) | 2013-08-20 |
US9861473B2 (en) | 2018-01-09 |
US20130345799A1 (en) | 2013-12-26 |
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