JP4726045B2 - 血液透析装置 - Google Patents
血液透析装置 Download PDFInfo
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- JP4726045B2 JP4726045B2 JP2005112552A JP2005112552A JP4726045B2 JP 4726045 B2 JP4726045 B2 JP 4726045B2 JP 2005112552 A JP2005112552 A JP 2005112552A JP 2005112552 A JP2005112552 A JP 2005112552A JP 4726045 B2 JP4726045 B2 JP 4726045B2
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- 238000001631 haemodialysis Methods 0.000 title claims description 38
- 230000000322 hemodialysis Effects 0.000 title claims description 38
- 239000008280 blood Substances 0.000 claims description 106
- 210000004369 blood Anatomy 0.000 claims description 105
- 238000000502 dialysis Methods 0.000 claims description 89
- 238000011282 treatment Methods 0.000 claims description 87
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 69
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- 102100029361 Aromatase Human genes 0.000 description 3
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- 238000010586 diagram Methods 0.000 description 3
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
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- 239000000385 dialysis solution Substances 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 230000007937 eating Effects 0.000 description 2
- 230000029142 excretion Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000002637 fluid replacement therapy Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 241001227124 Dialytes Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
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- 238000007485 conventional hemodialysis Methods 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
- A61M1/1611—Weight of the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1613—Profiling or modelling of patient or predicted treatment evolution or outcome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
- A61M1/341—Regulation parameters by measuring the filtrate rate or volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/207—Blood composition characteristics hematocrit
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- External Artificial Organs (AREA)
Description
本実施形態に係る血液透析装置は、患者の血液を体外循環させつつ血液透析処理及び除水を行うためのもので、図1に示すように、患者の血液を体外循環させるための血液回路1と、該血液回路1に接続されて血液透析処理を行うためのダイアライザ2と、該ダイアライザ2に接続されて透析液を供給しつつ除水する透析装置本体6とから主に構成されている。血液回路1は、同図に示すように、可撓性チューブから成る動脈側血液回路1a及び静脈側血液回路1bから主に構成されており、これら動脈側血液回路1aと静脈側血液回路1bの間にダイアライザ2が接続されている。
=(−UFV)/BW1×100(%)…(式1)
但し、BW2は、測定時点での患者の体重であるとともに、飲食又は***などによる患者の体重の増減は考慮していない。
={BV2(1−Ht2/100)−BV1(1−Ht1/100)}/{
BV1(1−Ht1/100)}×100
=(BV2−BV1−BV2×Ht2/100+BV1×Ht1/100)
/{BV1(1−Ht1/100)}×100
=(BV2/BV1−1)/(1−Ht1/100)×100
=(Ht1/Ht2−1)/(1−Ht1/100)×100(%)…(式2)
1a 動脈側血液回路
1b 静脈側血液回路
2 ダイアライザ(透析処理手段)
3 血液ポンプ
4 静脈側ドリップチャンバ
5 ヘマトクリットセンサ
6 透析装置本体
7 透析液供給装置
8 除水ポンプ
9 入力手段
10 測定手段
11 算出手段
12 表示手段
13 報知手段
14 記憶手段
15 制御手段
16 除水量計測手段
Claims (9)
- 体外循環する患者の血液に対して血液透析処理及び除水ポンプの駆動により除水して透析治療を行う透析処理手段と、
前記除水ポンプの駆動量に基づき除水量を計測可能な除水量計測手段と、
該透析処理手段による透析治療中の患者の体重変化率、及び所定の血液指標の変化率を測定する測定手段と、
患者のドライウェイトと相関するとともに、前記測定手段で得られた体重変化率と血液指標の変化率とを関連付けするパラメータを透析治療中に算出する算出手段と、
を具備し、前記体重変化率は、前記除水量計測手段で計測された除水量と透析治療前の患者の体重とから得られることを特徴とする血液透析装置。 - 前記パラメータは、前記体重変化率と、体外循環する血液の濃度に基づいて得られる血液指標の変化率とから算出されることを特徴とする請求項1記載の血液透析装置。
- 前記血液の濃度から体外循環する血液の循環血漿量変化率を算出し、該循環血漿量変化率を前記血液指標の変化率とすることを特徴とする請求項2記載の血液透析装置。
- 前記算出手段で算出されたパラメータを表示する表示手段を具備したことを特徴とする請求項1〜請求項3の何れか1つに記載の血液透析装置。
- 前記表示手段は、前記算出手段で算出されたパラメータの経時的変化をグラフとして表示することを特徴とする請求項4記載の血液透析装置。
- 前記パラメータの適正範囲を設定するとともに、前記算出手段にて算出されたパラメータが適正範囲を逸脱した場合、報知する報知手段を具備したことを特徴とする請求項1〜請求項5の何れか1つに記載の血液透析装置。
- 前記パラメータの適正範囲を設定するとともに、前記算出手段にて算出されたパラメータが適正範囲を逸脱した場合、当該適正範囲内となるよう前記透析処理手段を制御するための制御手段を具備したことを特徴とする請求項1〜請求項6の何れか1つに記載の血液透析装置。
- 前記算出手段にて算出されたパラメータを記憶する記憶手段を具備するとともに、該記憶手段で記憶されたパラメータ又はその経時的変化を他の透析治療中又はその透析治療前後に表示させ得ることを特徴とする請求項1〜請求項7の何れか1つに記載の血液透析装置。
- 前記記憶手段は、外部端末と接続されて成り、前記算出手段にて算出されたパラメータを当該外部端末に送信し得ることを特徴とする請求項8記載の血液透析装置。
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005112552A JP4726045B2 (ja) | 2005-04-08 | 2005-04-08 | 血液透析装置 |
DE602006021163T DE602006021163D1 (de) | 2005-04-08 | 2006-02-28 | Hämodialysator |
CN2006800113179A CN101193667B (zh) | 2005-04-08 | 2006-02-28 | 血液透析装置和血液透析方法 |
EP06714866A EP1872811B1 (en) | 2005-04-08 | 2006-02-28 | Hemodialyzer |
PCT/JP2006/303729 WO2006112154A1 (ja) | 2005-04-08 | 2006-02-28 | 血液透析装置及び血液透析方法 |
TW095111714A TWI372637B (en) | 2005-04-08 | 2006-04-03 | Dialyzer |
US11/278,745 US20060226079A1 (en) | 2005-04-08 | 2006-04-05 | Hemodialysis apparatus and method for hemodialysis |
US12/973,008 US20110089111A1 (en) | 2005-04-08 | 2010-12-20 | Hemodialysis apparatus and method for hemodialysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005112552A JP4726045B2 (ja) | 2005-04-08 | 2005-04-08 | 血液透析装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006288625A JP2006288625A (ja) | 2006-10-26 |
JP4726045B2 true JP4726045B2 (ja) | 2011-07-20 |
Family
ID=37082178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005112552A Active JP4726045B2 (ja) | 2005-04-08 | 2005-04-08 | 血液透析装置 |
Country Status (7)
Country | Link |
---|---|
US (2) | US20060226079A1 (ja) |
EP (1) | EP1872811B1 (ja) |
JP (1) | JP4726045B2 (ja) |
CN (1) | CN101193667B (ja) |
DE (1) | DE602006021163D1 (ja) |
TW (1) | TWI372637B (ja) |
WO (1) | WO2006112154A1 (ja) |
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- 2006-02-28 WO PCT/JP2006/303729 patent/WO2006112154A1/ja active Application Filing
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Also Published As
Publication number | Publication date |
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DE602006021163D1 (de) | 2011-05-19 |
TW200642703A (en) | 2006-12-16 |
CN101193667A (zh) | 2008-06-04 |
WO2006112154A1 (ja) | 2006-10-26 |
CN101193667B (zh) | 2010-04-21 |
US20110089111A1 (en) | 2011-04-21 |
EP1872811B1 (en) | 2011-04-06 |
EP1872811A1 (en) | 2008-01-02 |
JP2006288625A (ja) | 2006-10-26 |
EP1872811A4 (en) | 2009-11-25 |
TWI372637B (en) | 2012-09-21 |
US20060226079A1 (en) | 2006-10-12 |
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