WO2008065753A1 - Dispositif de purification du sang - Google Patents

Dispositif de purification du sang Download PDF

Info

Publication number
WO2008065753A1
WO2008065753A1 PCT/JP2007/001316 JP2007001316W WO2008065753A1 WO 2008065753 A1 WO2008065753 A1 WO 2008065753A1 JP 2007001316 W JP2007001316 W JP 2007001316W WO 2008065753 A1 WO2008065753 A1 WO 2008065753A1
Authority
WO
WIPO (PCT)
Prior art keywords
blood
circuit
introduction part
pressure
opening
Prior art date
Application number
PCT/JP2007/001316
Other languages
English (en)
Japanese (ja)
Inventor
Hiroshi Nimura
Yoshiro Ueda
Original Assignee
Nikkiso Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikkiso Company Limited filed Critical Nikkiso Company Limited
Publication of WO2008065753A1 publication Critical patent/WO2008065753A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor

Definitions

  • the present invention relates to a blood purification apparatus in which a pressure measuring chain is connected in the middle of a blood circuit for circulating a patient's blood extracorporeally.
  • a hemodialysis apparatus having a blood circuit composed of a flexible tube that circulates the blood of a patient extracorporeally is used.
  • the blood circuit in this hemodialysis apparatus includes an arterial blood circuit in which an arterial puncture needle for collecting blood from a patient is attached to the tip, and a venous blood circuit in which a venous puncture needle for returning blood to the patient is attached to the tip.
  • the dialyzer is interposed between the arterial blood circuit and the venous blood circuit to purify the blood circulating outside the body.
  • the blood circuit (at least one of the arterial blood circuit and the venous blood circuit) is formed of a resin molded product having a large inner diameter accommodating space inside the blood circuit.
  • a drip chamber is connected.
  • a pressure monitor line is extended from the air layer side formed in the accommodating space, and a pressure measuring means is connected to the extended end. ing.
  • the blood pressure of the patient who is undergoing dialysis treatment can be monitored by the pressure monitor line together with the defoaming.
  • the drip chamber monitors the pressure of the blood while defoaming the blood circulating outside the body. Therefore, the liquid level in the accommodation space (the blood liquid level) by the air supplemented by the defoaming action The position of the surface has changed, making it difficult to accurately measure the pressure of blood circulating outside the body. Therefore, a separate level adjustment line is usually connected to the dripping chamber.
  • the level adjustment line is extended from the air layer side of the drip chamber, and a syringe or the like is connected to the front end, and air is sent to the air layer by the syringe.
  • a syringe or the like is connected to the front end, and air is sent to the air layer by the syringe.
  • Patent Document 1 Japanese Patent Laid-Open No. 2 0 06 _ 1 0 2 2 3 7
  • the drip chamber in the conventional blood purification apparatus requires a level adjustment line for adjusting the liquid level in addition to the pressure monitor line, a plurality of lines are extended from one chamber. As a result, handling was inconvenient and caused a connection error in each line.
  • the drip chamber is exclusively used for defoaming, and a chamber for measuring blood pressure (pressure measuring chamber) is provided separately from the drip chamber, but in this case, the pressure measuring chamber is circulated. When air bubbles are generated from the blood, the air level changes due to the air, making it difficult to accurately measure the blood pressure.
  • the present invention has been made in view of such circumstances, and a blood purification apparatus including a pressure measurement chamber capable of measuring a blood pressure more accurately while suppressing a change in liquid level. Is to provide.
  • the invention according to claim 1 includes a blood circuit including an arterial blood circuit and a venous blood circuit for extracorporeally circulating a patient's blood, a blood pump disposed in the arterial blood circuit, and the arterial side.
  • a blood purification unit that is connected between the blood circuit and the venous blood circuit and purifies blood flowing through the blood circuit; and a storage space that is connected in the middle of the blood circuit and has a predetermined capacity;
  • a pressure measuring chamber in which a pressure monitor line for measuring the pressure of blood flowing through the blood circuit is extended, and connected downstream of the connecting portion of the blood measuring circuit in the blood circuit
  • a blood purification apparatus comprising a dripping chamber for removing the blood of a patient flowing through the blood circuit.
  • a blood deriving unit for deriving the blood introduced from the blood introduction unit which covers the entire area of the opening of the blood introduction unit and opens.
  • the invention according to claim 2 is the blood purification apparatus according to claim 1, wherein the arterial blood circuit, the blood purification means, and the venous blood circuit are prefilled with a priming solution, and the pressure measurement
  • the working chamber is characterized in that, by driving the blood pump, a liquid layer is formed in which the upper part is composed of a priming liquid and the lower part is composed of blood.
  • the invention described in claim 3 is the blood purification apparatus according to claim 1 or 2, wherein the opening of the blood introduction part in the pressure measuring chamber enters into the opening of the blood guiding part. It is characterized by overlapping.
  • the invention according to claim 4 is the blood purification apparatus according to claim 1 or 2, wherein the clearance of a minute dimension between the blood introduction part and the blood lead-out part in the pressure measurement chamber is used. A mesh is formed.
  • the pressure measuring chamber is formed in the lower part of the accommodation space, and introduces blood while opening near the bottom surface of the accommodation space, and the blood introduction part.
  • the openings are extended to a position where the openings are opposed to each other through a clearance of a minute dimension, and open over substantially the entire area of the opening of the blood introduction section, and the blood introduced from the blood introduction section is derived. Since it has a blood outlet, the bubbles in the blood introduced from the blood inlet are reliably led out from the blood outlet. Therefore, it is possible to more accurately measure the blood pressure by suppressing the accumulation of bubbles in the storage space and suppressing the change in the liquid level.
  • the pressure measuring chamber is driven by the blood pump.
  • a liquid layer consisting of priming liquid at the upper part and blood at the lower part is formed. Can be avoided.
  • blood is only slightly accumulated in the lower part of the liquid layer in the accommodation space, the extracorporeal blood volume can be reduced and the burden on the patient can be reduced.
  • the blood introduction part in the pressure measuring chamber overlaps when the opening enters the opening of the blood outlet part, so that the blood introduction part is introduced from the blood introduction part. Air bubbles in the blood can be more reliably guided to the blood outlet, and the change in the liquid level can be more reliably suppressed to accurately measure the blood pressure.
  • the mesh is formed in the minute dimension clearance between the blood introduction part and the blood lead-out part in the pressure measurement chamber, the mesh is mixed in the accommodation space. Foreign matter or the like can be captured with a mesh, and it can be avoided that the foreign matter or the like is derived from the blood outlet and flows into the blood circuit.
  • the blood purification apparatus is for purifying a patient's blood while circulating it extracorporeally, and is applied to a dialysis apparatus used in dialysis treatment.
  • a dialyzer is mainly composed of a blood circuit 1 connected to a dialer 2 as a blood purification means, and a dialyzer body 6 for removing water while supplying dialysate to the dialyzer 2.
  • the blood circuit 1 is mainly composed of an arterial blood circuit 1 a and a venous blood circuit 1 b made of a flexible tube.
  • the arterial blood circuit 1 a and the venous blood Dialer 2 is connected between circuit 1 b.
  • the arterial blood circuit 1 a has an arterial puncture needle a connected to the tip thereof, and an iron-type blood pump 3, a pressure measuring chamber 4, and a defoaming drip chamber along the way 5 (arterial drip chamber) is installed and connected.
  • a physiological saline line 10 having a physiological saline drip chamber 9 is extended in the middle, and a saline bag 8 containing a physiological saline at the tip 8 Is connected.
  • a venous puncture needle b is connected to the distal end of the venous blood circuit 1b, and a drip chamber 12 (venous drip chamber) for removing bubbles and a bubble detector 11 are connected to the venous blood circuit 1b.
  • a drip chamber 12 venous drip chamber
  • the pressure measuring chamber 4 is connected between the site of connection with the physiological saline line 10 in the arterial blood circuit 1a and the site of the blood pump 3, and the drip chamber 5 Is connected downstream of the connection part of the pressure measuring chamber 4 and between the connection part of the blood pump 3 and the connection part of the dialyzer 2.
  • the bubble detector 11 is mainly composed of a sensor 1 1a for detecting bubbles and a clamp 1 1b for cutting off the venous blood circuit 1b when bubbles are detected.
  • reference numeral 1 2 denotes a syringe pump for administering a drug or the like to the blood flowing through the blood circuit 1.
  • physiological saline for example, saline / Kug 8
  • saline / Kug 8 is used as a priming solution in advance in the arterial blood circuit 1a, the blood flow path of the dialyzer 2 and the venous side blood circuit 1b.
  • the blood pump 3 is driven, the physiological saline flows into the arterial blood circuit. 1a The blood is gradually replaced from the tip.
  • the dialyzer 2 is formed with a blood introduction port 2a, a blood outlet port 2b, a dialysate inlet port 2c, and a dialysate outlet port 2d in its casing, Of these, the proximal end of the arterial blood circuit 1a is connected to the blood introduction port 2a, and the proximal end of the venous blood circuit 1b is connected to the blood outlet port 2b.
  • the dialysate introduction port 2 c and the dialysate outlet port 2 d are connected to a dialysate introduction line L 1 and a dialysate discharge line L 2 extending from the dialyzer body 6, respectively.
  • a plurality of hollow fibers are accommodated in the dialyzer 2, the inside of the hollow fibers is used as a blood flow path, and dialysis is performed between the outer peripheral surface of the hollow fibers and the inner peripheral surface of the casing. It is a liquid flow path.
  • a hollow fiber membrane is formed in the hollow fiber by forming a number of minute holes (pores) penetrating the outer peripheral surface and the inner peripheral surface, and impurities in the blood and the like are passed through the membrane in the dialysate. It is comprised so that it can permeate
  • a dual pump, a dewatering pump, etc. (not shown) are arranged, and in addition to the action of the dialyzer 2, the blood circuit 1 is circulated outside the body. Dialysis treatment can be performed. Further, a pressure gauge 7 is formed in the dialyzer body 6, and the pressure gauge 7 is connected to a pressure monitor line L 3 extending from the pressure measurement chamber 4 via a filter (not shown). Yes.
  • the pressure measuring chamber 4 is connected in the middle of the arterial blood circuit 1 a (blood circuit 1) and has a predetermined capacity of the accommodating space 4 a, and the arterial side from the accommodating space 4 a
  • the pressure monitor line L 3 for measuring the pressure of the blood flowing through the blood circuit 1 a is extended.
  • the pressure measuring chamber 4 has a housing space 4a formed in the case C, and a blood introduction part 4b formed in the lower part thereof, and a side surface. And a blood lead-out portion 4 c extending from the head.
  • the blood introduction part 4b is a part where blood flowing through the arterial blood circuit 1a can be introduced upward from below while opening upward in the vicinity of the bottom surface of the accommodation space 4a.
  • the blood outlet 4c extends to the position where the openings (4ba, 4be) face each other through the clearance of the minute dimension t with respect to the blood inlet 4b.
  • the blood introduction part 4 b opening 4 b Covers the entire area of a (see Fig. 3), and guides the blood introduced from the blood introduction part 4b out of the accommodation space 4a (that is, downstream of the arterial blood circuit 1a). .
  • the opening 4 ca of the blood outlet 4 c is set to be larger than the opening 4 ba of the blood introduction part 4 b, and the opening 4 ca passes above the opening 4 ba through a minute clearance. Covering (a state where the projected area of the opening 4 ba is entirely within the opening of the opening 4 ca), the blood led from the blood introduction part 4 b or physiological saline as a priming solution is not cleared. Most of the space is filled from the blood outlet 4c while being filled into the accommodation space 4a.
  • the arterial blood circuit 1 a, the blood flow path of the dialyzer 2 and the venous blood circuit 1 b are filled with physiological saline as a brimming solution, and then the arterial puncture needle a and the venous side are filled.
  • the patient is punctured with the puncture needle b and the blood pump 3 is driven.
  • the physiological saline is guided from the blood introduction part 4 b in the pressure measurement chamber 4, and as shown in FIG. 4, a single layer of physiological saline (a physiological saline layer) is contained in the accommodation space 4 a. ) Will be formed.
  • the extracorporeal blood volume can be reduced and the burden on the patient can be reduced.
  • the blood layer in the accommodation space 4a; S is the lower part of the physiological saline layer, so it is in direct contact with the air layer. It will not be. Therefore, it is possible to prevent blood in the blood layer; S from coming into contact with the air in the air layer, thereby preventing thrombus from being promoted or foaming.
  • the pressure measuring chamber 4 includes a blood introduction part 4b that introduces blood while opening in the vicinity of the bottom surface of the accommodation space 4a, and a clearance of a minute dimension t with respect to the blood introduction part 4b.
  • a blood introduction part 4b that introduces blood while opening in the vicinity of the bottom surface of the accommodation space 4a, and a clearance of a minute dimension t with respect to the blood introduction part 4b.
  • the bubbles contained in the blood introduced from the blood introduction part 4b have a property of flowing upward because the specific gravity is lighter than that of the blood, and move along the blood flow, so that the clearance It is avoided that the blood reaches the S side through the blood and is smoothly led out from the blood outlet 4c. Therefore, it is possible to suppress the accumulation of bubbles in the storage space 4a, and to suppress the change in the liquid level in the storage space 4a.
  • the air layer 4 a side and the pressure gauge 7 communicate with each other via the pressure monitor line L 3, and the value measured by the pressure gauge 7 is the arterial blood circuit 1 a ( This indicates the pressure of blood flowing through the upstream side of blood pump 3).
  • the blood pressure can be measured more accurately.
  • the pressure measuring chamber 4 exclusively measures the blood pressure on the artery side, and bubbles contained in the flowing blood are removed by the downstream drip chamber 5. Therefore, bubbles will reach the dialyzer 2 Can be avoided.
  • the blood purification apparatus is for purifying a patient's blood while circulating externally, and is applied to a dialysis apparatus used in dialysis treatment.
  • a dialysis apparatus is substantially the same as that shown in FIG. 1, and only the pressure measuring chamber connected to the arterial blood circuit 1a is different.
  • the same components as those in the previous embodiment are denoted by the same reference numerals, and detailed description thereof is omitted.
  • the pressure measuring chamber 4 ′ has an accommodation space 4 a formed in the case C, and the blood introduction part 4 formed in the lower part thereof. b 'and a blood outlet 4c' extending downward from the upper surface.
  • the blood introduction part 4 b ′ is a part where blood flowing through the arterial blood circuit 1 a can be introduced upward from below while opening upward near the bottom surface of the accommodation space 4 a.
  • the blood outlet 4c ' extends to a position where the openings of the blood inlet 4c' face each other through a clearance of a minute dimension t with respect to the blood inlet 4b '(the suspension of the present embodiment is drooping)
  • the blood introduction part 4 b ′ covers the entire opening (the diameter of the blood introduction part 4 b ′ is larger than the opening of the blood introduction part 4 c ′), and the blood introduction part 4
  • the blood introduced from b ′ is led out of the accommodation space 4a (that is, downstream of the arterial blood circuit 1a).
  • the opening of the blood introduction part 4 b ′ is configured to enter into the opening of the blood outlet part 4 c ′, and overlaps.
  • the pressure measuring chamber 4 ' is driven by the blood pump 3, so that the upper part is physiological saline (saline layer) and the lower part is blood (blood layer; S).
  • the bubbles contained in the blood derived from the blood deriving portion 4 c ′ reach the downstream drip chamber 5 (see FIG. 1), where the bubbles are removed.
  • the openings of the blood introduction part 4b 'and the blood lead-out part 4c' in the pressure measurement chamber 4 ' are overlapped, so that they are introduced from the blood introduction part 4b'.
  • the air bubbles in the blood can be more reliably guided to the blood outlet 4 c ′, and the change in the liquid level can be more reliably suppressed to accurately measure the blood pressure.
  • the blood purification apparatus is for purifying a patient's blood while circulating externally, and is applied to a dialysis apparatus used in dialysis treatment.
  • a dialysis apparatus is substantially the same as that shown in FIG. 1, and only the pressure measuring chamber connected to the arterial blood circuit 1a is different.
  • the same components as those in the previous embodiment are denoted by the same reference numerals, and detailed description thereof is omitted.
  • the pressure measuring chamber 4 As shown in Fig. 7, the pressure measuring chamber 4 "according to the present embodiment has an accommodation space 4a formed in the case C, and the blood introduction part 4 formed in the lower part thereof. b "and a blood outlet 4c" extending downward from the upper surface.
  • the blood inlet 4b opens upward near the bottom surface of the accommodating space 4a and In the site where blood flowing through the side blood circuit 1a can be introduced from below to above
  • the blood outlet 4c extends to a position where the openings of the blood inlet 4c" face each other through a clearance of a minute dimension t with respect to the blood inlet 4b "(in this embodiment, it is drooping)
  • the blood introduced from the blood introduction part 4 b" is stored outside the accommodation space 4 a.
  • a mesh 4 d is formed in the clearance between the opening of the blood introduction part 4 b ′′ and the opening of the blood outlet part 4 c ′′.
  • the pressure measuring chamber 4 is driven by the blood pump 3, so that the upper part is physiological saline (saline layer) and the lower part is blood (blood layer; S).
  • a double liquid layer consisting of the blood layer; the blood of S It only accumulates slightly in the lower part of 4a.
  • the bubbles contained in the blood derived from the blood deriving section 4 c ′′ reach the drip chamber 5 on the downstream side (see FIG. 1), where the bubbles are removed.
  • the mesh 4d is formed in the clearance of the minute dimension t between the blood introduction part 4b "and the blood outlet part 4c" in the pressure measurement chamber 4 ". Therefore, foreign matter mixed in the accommodation space 4a can be captured by the mesh 4d, and the foreign matter is prevented from being led out from the blood outlet 4c "and flowing into the blood circuit 1. can do.
  • the present invention is not limited to the above, and for example, the pressure measuring chamber to be connected to the blood circuit is shown in FIG. Is not extended into the storage space 4a, but only the blood outlet 4c is extended in the storage space 4a and the openings are opposed to each other, or as shown in FIG.
  • the clearance between 4 b and blood outlet 4 c may be formed by slit 4 e.
  • a single hole (such as a round hole) may be formed instead of the slit 4a.
  • the blood introduction part 4b and the blood lead-out part 4c are not limited to those in which the respective axes coincide with each other as in the above embodiment.
  • the axis of 4b and the axis of blood outlet 4c may be displaced substantially in parallel, or as shown in FIG. 11, either one (in this figure, blood introduction part 4b) is the other ( It may be extended with a predetermined angle with respect to the axis of the blood outlet 4c).
  • the blood outlet 4c is opened so as to cover substantially the entire opening of the blood inlet 4b (the projected area of the opening of the blood inlet 4b is equal to that of the blood outlet 4c). It is necessary to form so that the blood introduced from the blood introduction part 4 b is led out.
  • both the blood introduction part 4 b and the blood lead-out part 4 c may be configured to extend at a predetermined angle from the axis of the case C.
  • the blood outlet 4 c is extended in an inverted U shape in the accommodation space 4 a so that the opening faces the opening of the blood introduction part 4 b. Good.
  • the openings of each other face each other with a minute dimension clearance, the position of the clearance is set near the bottom surface of the accommodation space, and the blood outlet 4c It is necessary to cover almost the entire opening of part 4b.
  • the dialysis machine body 6 is applied to either a dialysis monitoring device that does not include a dialysate supply mechanism, or a personal dialyzer that includes a dialysate supply mechanism. You may do it.
  • the present invention can be applied to other blood purification apparatuses such as hemofiltration therapy and hemofiltration dialysis therapy in addition to hemodialysis therapy as in the embodiment.
  • a blood introduction part that is formed in the lower part of the accommodation space and introduces blood while opening in the vicinity of the bottom surface of the accommodation space, and the openings face each other with a minute dimension clearance with respect to the blood introduction part
  • a pressure measuring chamber having a blood lead-out part that extends to a position where the blood is introduced, covers substantially the entire opening of the blood introduction part, and leads out the blood introduced from the blood introduction part.
  • FIG. 1 is an overall schematic diagram showing a blood purification apparatus according to a first embodiment of the present invention.
  • FIG. 2 is a schematic cross-sectional view showing a pressure measurement chamber connected to a blood circuit in the blood purification apparatus.
  • FIG. 4 is a schematic diagram showing a state in which physiological saline (priming solution) is accommodated in the same pressure measurement chamber.
  • FIG. 5 is a schematic diagram showing a state in which blood is stored in addition to physiological saline (priming solution) in the same pressure measurement chamber.
  • FIG. 6 is a schematic cross-sectional view showing a pressure measuring chamber connected to the blood purification apparatus of the second embodiment of the present invention.
  • FIG. 7 is a schematic cross-sectional view showing a pressure measurement chamber connected to the blood purification apparatus of the third embodiment of the present invention.
  • FIG. 8 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.
  • FIG. 9 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.
  • FIG. 10 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.
  • FIG. 11 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.
  • FIG. 12 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.
  • FIG. 13 is a schematic cross-sectional view showing a pressure measurement chamber in still another embodiment of the present invention.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

L'objet de la présente invention est la mise au point d'un dispositif de purification du sang comprenant une chambre de mesure de pression qui peut supprimer un changement d'un niveau de liquide pour mesurer la pression du sang avec une meilleure précision. A cet effet, ledit dispositif de purification du sang comprend un circuit sanguin (1), une pompe à sang (3), un dialyseur (2) pour purifier le sang qui s'écoule dans le circuit sanguin (1), une chambre de mesure de pression (4) pour mesurer la pression du sang qui s'écoule dans le circuit sanguin (1), et une chambre de goutte à goutte (5) pour retirer les bulles du sang qui s'écoule dans le circuit sanguin (1). La chambre de mesure de pression (4) est formée sur la partie inférieure d'un espace de stockage (4a) et comprend une partie d'introduction de sang (4b), qui est ouverte au niveau d'une partie proche du fond de l'espace de stockage (4a), pour introduire le sang, ainsi qu'une partie de sortie de sang (4c) pour faire sortir le sang introduit par la partie d'introduction de sang (4b). La partie de sortie de sang (4c) s'étend vers la partie d'introduction de sang (4b) jusqu'à une position où l'ouverture de la partie de sortie de sang (4c) fait face à l'ouverture de la partie d'introduction de sang (4b), tout en offrant un espacement d'une très petite dimension t, et l'ouverture de la partie de sortie de sang (4c) recouvre sensiblement la totalité de la surface de l'ouverture de la partie d'introduction de sang (4b).
PCT/JP2007/001316 2006-11-29 2007-11-29 Dispositif de purification du sang WO2008065753A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006-321006 2006-11-29
JP2006321006A JP5078122B2 (ja) 2006-11-29 2006-11-29 血液浄化装置

Publications (1)

Publication Number Publication Date
WO2008065753A1 true WO2008065753A1 (fr) 2008-06-05

Family

ID=39467553

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/001316 WO2008065753A1 (fr) 2006-11-29 2007-11-29 Dispositif de purification du sang

Country Status (2)

Country Link
JP (1) JP5078122B2 (fr)
WO (1) WO2008065753A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282881A (en) * 1979-05-10 1981-08-11 Sorenson Research Co., Inc. Manometer for infusion apparatus
JP2005065888A (ja) * 2003-08-22 2005-03-17 Nikkiso Co Ltd 血管アクセス監視方法および医療装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH041948Y2 (fr) * 1986-06-20 1992-01-23
ES2106420T3 (es) * 1993-09-01 1997-11-01 Fresenius Ag Separador de aire.
US5591344A (en) * 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
US5951870A (en) * 1997-10-21 1999-09-14 Dsu Medical Corporation Automatic priming of blood sets
JP4088918B2 (ja) * 2002-09-13 2008-05-21 東レ・メディカル株式会社 血液透析装置
JP4094600B2 (ja) * 2004-10-06 2008-06-04 日機装株式会社 血液浄化装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282881A (en) * 1979-05-10 1981-08-11 Sorenson Research Co., Inc. Manometer for infusion apparatus
JP2005065888A (ja) * 2003-08-22 2005-03-17 Nikkiso Co Ltd 血管アクセス監視方法および医療装置

Also Published As

Publication number Publication date
JP5078122B2 (ja) 2012-11-21
JP2008132196A (ja) 2008-06-12

Similar Documents

Publication Publication Date Title
JP3958733B2 (ja) 血液浄化装置
JP4726045B2 (ja) 血液透析装置
JP5914106B2 (ja) 血液浄化装置
US9872951B2 (en) Blood purification apparatus and priming method for the same
JP4798653B2 (ja) 血液浄化装置
JP6517023B2 (ja) 血液浄化装置
JP4716409B2 (ja) 血液浄化装置
WO2006038396A1 (fr) Dispositif de purification du sang
JP4290106B2 (ja) 血液浄化装置
WO2006040882A1 (fr) Appareil de dialyse du sang
JPH04253868A (ja) 血液浄化装置
JP6437349B2 (ja) 血液浄化装置
WO2016143841A1 (fr) Dispositif de purification du sang
JP5222706B2 (ja) 血液浄化装置及びその血液流量演算方法
ES2361560T3 (es) Máquina y unidad de tratamiento de sangre.
JP2010136745A (ja) 血液浄化装置
JP5078122B2 (ja) 血液浄化装置
JPWO2017171064A1 (ja) 血液浄化システム、及びそのプライミング方法
JP2010004905A (ja) 血液浄化装置
JP2019170856A (ja) 液面調整機構及び該液面調整機構を備える血液浄化装置
JP6017713B2 (ja) 血液浄化装置
JP6017712B2 (ja) 血液浄化装置
JP6017711B2 (ja) 血液浄化装置
JP6062580B2 (ja) 血液浄化装置
WO2023032960A1 (fr) Dispositif de purification du sang

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07828093

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07828093

Country of ref document: EP

Kind code of ref document: A1